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Illumina Body Map 2

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Results for ZBTB4

Z-value: 0.96

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Transcription factors associated with ZBTB4

Gene Symbol Gene ID Gene Info
ENSG00000174282.7 zinc finger and BTB domain containing 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZBTB4hg19_v2_chr17_-_7387524_7387597-0.232.1e-01Click!

Activity profile of ZBTB4 motif

Sorted Z-values of ZBTB4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_11370330 2.63 ENST00000241808.4
ENST00000435245.2
protamine 2
chr2_+_192109911 2.57 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
myosin IB
chr8_-_105479270 2.53 ENST00000521573.2
ENST00000351513.2
dihydropyrimidinase
chr1_+_196912902 2.49 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr2_+_192110199 2.45 ENST00000304164.4
myosin IB
chr20_+_3052264 2.41 ENST00000217386.2
oxytocin/neurophysin I prepropeptide
chr1_+_196788887 2.32 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr19_+_35596873 2.31 ENST00000313865.6
Uncharacterized protein
chr11_-_1016149 2.27 ENST00000532016.1
mucin 6, oligomeric mucus/gel-forming
chr11_-_72385437 2.24 ENST00000418754.2
ENST00000542969.2
ENST00000334456.5
phosphodiesterase 2A, cGMP-stimulated
chr3_-_128185811 2.04 ENST00000469083.1
DnaJ (Hsp40) homolog, subfamily B, member 8
chr14_+_85996471 1.91 ENST00000330753.4
fibronectin leucine rich transmembrane protein 2
chr17_+_34058639 1.89 ENST00000268864.3
RAS-like, family 10, member B
chr17_-_19265855 1.87 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9 protein domain 1
chr6_+_41606176 1.85 ENST00000441667.1
ENST00000230321.6
ENST00000373050.4
ENST00000446650.1
ENST00000435476.1
MyoD family inhibitor
chr7_+_87257701 1.85 ENST00000338056.3
ENST00000493037.1
RUN domain containing 3B
chr3_+_159943362 1.84 ENST00000326474.3
chromosome 3 open reading frame 80
chr5_-_146889619 1.72 ENST00000343218.5
dihydropyrimidinase-like 3
chr11_+_705193 1.40 ENST00000527199.1
EPS8-like 2
chr16_+_30996502 1.36 ENST00000353250.5
ENST00000262520.6
ENST00000297679.5
ENST00000562932.1
ENST00000574447.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr1_+_65886326 1.35 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
leptin receptor
chr12_+_5541267 1.33 ENST00000423158.3
neurotrophin 3
chr14_+_21569245 1.33 ENST00000556585.2
transmembrane protein 253
chr6_-_49430886 1.31 ENST00000274813.3
methylmalonyl CoA mutase
chr8_-_27468945 1.30 ENST00000405140.3
clusterin
chr8_-_27469196 1.27 ENST00000546343.1
ENST00000560566.1
clusterin
chr10_+_17851362 1.22 ENST00000331429.2
ENST00000457317.1
cDNA FLJ56855, highly similar to Macrophage mannose receptor 1
chr14_+_85996507 1.20 ENST00000554746.1
fibronectin leucine rich transmembrane protein 2
chr8_-_27468842 1.19 ENST00000523500.1
clusterin
chr15_-_40212363 1.18 ENST00000299092.3
G protein-coupled receptor 176
chr19_+_50433476 1.17 ENST00000596658.1
activating transcription factor 5
chr1_+_65886244 1.17 ENST00000344610.8
leptin receptor
chr15_+_90792760 1.15 ENST00000339615.5
ENST00000438251.1
tubulin tyrosine ligase-like family, member 13
chr22_+_29279552 1.12 ENST00000544604.2
zinc and ring finger 3
chr22_+_21987005 1.12 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr16_-_75301886 1.09 ENST00000393422.2
breast cancer anti-estrogen resistance 1
chr7_+_87257854 1.07 ENST00000394654.3
RUN domain containing 3B
chr8_-_27468717 1.05 ENST00000520796.1
ENST00000520491.1
clusterin
chrX_-_99665262 1.04 ENST00000373034.4
ENST00000255531.7
protocadherin 19
chr17_-_30186328 1.04 ENST00000302362.6
coordinator of PRMT5, differentiation stimulator
chr17_-_30185971 1.03 ENST00000378634.2
coordinator of PRMT5, differentiation stimulator
chr2_-_179343226 1.02 ENST00000434643.2
FK506 binding protein 7
chr13_-_21348050 1.00 ENST00000382754.4
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr16_+_66413128 0.99 ENST00000563425.2
cadherin 5, type 2 (vascular endothelium)
chr13_-_21348066 0.98 ENST00000382758.1
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr8_-_27469383 0.97 ENST00000519742.1
clusterin
chr16_-_30042580 0.96 ENST00000380495.4
family with sequence similarity 57, member B
chr19_+_6135646 0.96 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
acyl-CoA synthetase bubblegum family member 2
chr6_-_136847610 0.96 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr8_-_143851203 0.95 ENST00000521396.1
ENST00000317543.7
Ly6/neurotoxin 1
chr9_-_93405352 0.95 ENST00000375765.3
DIRAS family, GTP-binding RAS-like 2
chr3_-_128186091 0.93 ENST00000319153.3
DnaJ (Hsp40) homolog, subfamily B, member 8
chr9_-_80263220 0.91 ENST00000341700.6
guanine nucleotide binding protein (G protein), alpha 14
chr19_-_17356697 0.91 ENST00000291442.3
nuclear receptor subfamily 2, group F, member 6
chr22_+_32439019 0.89 ENST00000266088.4
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr9_+_70971815 0.89 ENST00000396392.1
ENST00000396396.1
phosphoglucomutase 5
chr9_-_71629010 0.89 ENST00000377276.2
protein kinase, cAMP-dependent, catalytic, gamma
chr8_-_71581377 0.89 ENST00000276590.4
ENST00000522447.1
lactamase, beta 2
chr7_-_18067478 0.89 ENST00000506618.2
phosphoribosyl pyrophosphate synthetase 1-like 1
chr2_+_74685413 0.89 ENST00000233615.2
WW domain binding protein 1
chr5_-_150948414 0.88 ENST00000261800.5
FAT atypical cadherin 2
chr14_+_23305760 0.88 ENST00000311852.6
matrix metallopeptidase 14 (membrane-inserted)
chr2_+_74685527 0.87 ENST00000393972.3
ENST00000409737.1
ENST00000428943.1
WW domain binding protein 1
chr3_-_57583130 0.86 ENST00000303436.6
ADP-ribosylation factor 4
chr1_+_169075554 0.86 ENST00000367815.4
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr20_-_36793774 0.85 ENST00000361475.2
transglutaminase 2
chrX_-_129519511 0.84 ENST00000276218.2
G protein-coupled receptor 119
chr8_-_74205851 0.84 ENST00000396467.1
ribosomal protein L7
chr3_+_188889737 0.80 ENST00000345063.3
tumor protein p63 regulated 1
chr13_-_33780133 0.80 ENST00000399365.3
StAR-related lipid transfer (START) domain containing 13
chr14_-_23446900 0.79 ENST00000556731.1
ajuba LIM protein
chr3_-_57583052 0.78 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr19_+_19144384 0.78 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr12_-_120805872 0.77 ENST00000546985.1
musashi RNA-binding protein 1
chr3_+_148583043 0.77 ENST00000296046.3
carboxypeptidase A3 (mast cell)
chr19_-_19144243 0.77 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr17_-_15165854 0.75 ENST00000395936.1
ENST00000395938.2
peripheral myelin protein 22
chr15_-_40213080 0.74 ENST00000561100.1
G protein-coupled receptor 176
chr20_-_36793663 0.74 ENST00000536701.1
ENST00000536724.1
transglutaminase 2
chr14_-_69446034 0.73 ENST00000193403.6
actinin, alpha 1
chr19_+_36024310 0.72 ENST00000222286.4
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr22_+_50312316 0.71 ENST00000328268.4
cysteine-rich with EGF-like domains 2
chr10_+_37414785 0.69 ENST00000374660.1
ENST00000602533.1
ENST00000361713.1
ankyrin repeat domain 30A
chr22_+_50312379 0.69 ENST00000407217.3
ENST00000403427.3
cysteine-rich with EGF-like domains 2
chrX_-_71526813 0.68 ENST00000246139.5
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr14_-_69445968 0.67 ENST00000438964.2
actinin, alpha 1
chr11_+_1093318 0.67 ENST00000333592.6
mucin 2, oligomeric mucus/gel-forming
chr14_-_23822080 0.67 ENST00000397267.1
ENST00000354772.3
solute carrier family 22, member 17
chr7_+_30811004 0.67 ENST00000265299.6
family with sequence similarity 188, member B
chr10_+_123922941 0.66 ENST00000360561.3
transforming, acidic coiled-coil containing protein 2
chr17_-_30185946 0.64 ENST00000579741.1
coordinator of PRMT5, differentiation stimulator
chr4_-_113437328 0.64 ENST00000313341.3
neurogenin 2
chr11_+_1092184 0.64 ENST00000361558.6
mucin 2, oligomeric mucus/gel-forming
chr14_+_23305783 0.63 ENST00000547279.1
matrix metallopeptidase 14 (membrane-inserted)
chr11_-_64546202 0.61 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
splicing factor 1
chr19_-_12476443 0.61 ENST00000242804.4
ENST00000438182.1
zinc finger protein 442
chr4_+_183370146 0.61 ENST00000510504.1
teneurin transmembrane protein 3
chr10_+_18098352 0.60 ENST00000239761.3
mannose receptor, C type 1
chr14_-_74551096 0.59 ENST00000350259.4
aldehyde dehydrogenase 6 family, member A1
chr1_+_154947126 0.58 ENST00000368439.1
CDC28 protein kinase regulatory subunit 1B
chr6_+_159290917 0.58 ENST00000367072.1
chromosome 6 open reading frame 99
chr9_-_131709858 0.57 ENST00000372586.3
dolichol kinase
chr12_+_57388230 0.57 ENST00000300098.1
G protein-coupled receptor 182
chr5_+_173416162 0.57 ENST00000340147.6
chromosome 5 open reading frame 47
chr14_+_74416989 0.57 ENST00000334571.2
ENST00000554920.1
coenzyme Q6 monooxygenase
chr1_+_33219592 0.56 ENST00000373481.3
KIAA1522
chr4_-_156297949 0.56 ENST00000515654.1
microtubule-associated protein 9
chr19_-_49865639 0.54 ENST00000593945.1
ENST00000601519.1
ENST00000539846.1
ENST00000596757.1
ENST00000311227.2
TEA domain family member 2
chr1_+_154947148 0.54 ENST00000368436.1
ENST00000308987.5
CDC28 protein kinase regulatory subunit 1B
chr12_-_91348949 0.53 ENST00000358859.2
coiled-coil glutamate-rich protein 1
chr11_-_46940074 0.52 ENST00000378623.1
ENST00000534404.1
low density lipoprotein receptor-related protein 4
chr15_+_42696992 0.52 ENST00000561817.1
calpain 3, (p94)
chr17_-_56595196 0.50 ENST00000579921.1
ENST00000579925.1
ENST00000323456.5
myotubularin related protein 4
chr16_+_85391069 0.49 ENST00000568080.1
Uncharacterized protein
chr3_+_187957646 0.49 ENST00000457242.1
LIM domain containing preferred translocation partner in lipoma
chr12_-_80084594 0.48 ENST00000548426.1
PRKC, apoptosis, WT1, regulator
chr10_-_35104185 0.48 ENST00000374789.3
ENST00000374788.3
ENST00000346874.4
ENST00000374794.3
ENST00000350537.4
ENST00000374790.3
ENST00000374776.1
ENST00000374773.1
ENST00000545693.1
ENST00000545260.1
ENST00000340077.5
par-3 family cell polarity regulator
chr19_-_18902106 0.47 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
cartilage oligomeric matrix protein
chr5_-_137090028 0.47 ENST00000314940.4
heterogeneous nuclear ribonucleoprotein A0
chr7_+_100136811 0.46 ENST00000300176.4
ENST00000262935.4
ArfGAP with FG repeats 2
chr9_-_16215897 0.45 ENST00000433347.1
chromosome 9 open reading frame 92
chr1_-_203055129 0.45 ENST00000241651.4
myogenin (myogenic factor 4)
chr3_-_19988462 0.44 ENST00000344838.4
EF-hand domain family, member B
chr19_+_1275917 0.44 ENST00000469144.1
chromosome 19 open reading frame 24
chr19_+_15121532 0.44 ENST00000292574.3
coiled-coil domain containing 105
chr14_-_69445793 0.44 ENST00000538545.2
ENST00000394419.4
actinin, alpha 1
chr17_+_7487146 0.43 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr12_+_112204691 0.43 ENST00000416293.3
ENST00000261733.2
aldehyde dehydrogenase 2 family (mitochondrial)
chr18_+_12658185 0.43 ENST00000400514.2
Uncharacterized protein
chr2_+_131331904 0.42 ENST00000440359.1
Uncharacterized protein
chr18_+_12658209 0.41 ENST00000400512.1
Uncharacterized protein
chr17_-_9479128 0.41 ENST00000574431.1
syntaxin 8
chr20_-_43438912 0.40 ENST00000541604.2
ENST00000372851.3
regulating synaptic membrane exocytosis 4
chr4_+_128554081 0.39 ENST00000335251.6
ENST00000296461.5
inturned planar cell polarity protein
chr2_-_10952922 0.39 ENST00000272227.3
protein disulfide isomerase family A, member 6
chr17_-_15165825 0.39 ENST00000426385.3
peripheral myelin protein 22
chr1_-_165738085 0.39 ENST00000464650.1
ENST00000392129.6
transmembrane and coiled-coil domains 1
chr2_-_10952832 0.38 ENST00000540494.1
protein disulfide isomerase family A, member 6
chr12_+_6561190 0.37 ENST00000544021.1
ENST00000266556.7
TAP binding protein-like
chr9_-_136242956 0.37 ENST00000371989.3
ENST00000485435.2
surfeit 4
chr4_-_156297919 0.37 ENST00000450097.1
microtubule-associated protein 9
chr20_+_61147651 0.36 ENST00000370527.3
ENST00000370524.2
chromosome 20 open reading frame 166
chr18_-_47340297 0.36 ENST00000586485.1
ENST00000587994.1
ENST00000586100.1
ENST00000285093.10
acetyl-CoA acyltransferase 2
chr11_+_125462690 0.35 ENST00000392708.4
ENST00000529196.1
ENST00000531491.1
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
chr1_-_165738072 0.35 ENST00000481278.1
transmembrane and coiled-coil domains 1
chr1_+_10534944 0.34 ENST00000356607.4
ENST00000538836.1
ENST00000491661.2
peroxisomal biogenesis factor 14
chrM_+_3299 0.34 ENST00000361390.2
mitochondrially encoded NADH dehydrogenase 1
chr17_-_40264321 0.33 ENST00000430773.1
ENST00000413196.2
DEXH (Asp-Glu-X-His) box polypeptide 58
chr9_+_131181798 0.33 ENST00000420512.1
cerebral endothelial cell adhesion molecule
chr15_+_91498089 0.33 ENST00000394258.2
ENST00000555155.1
RCC1 domain containing 1
chr8_-_145691031 0.32 ENST00000424149.2
ENST00000530637.1
ENST00000306145.5
cysteine/histidine-rich 1
chr17_-_40264692 0.31 ENST00000591220.1
ENST00000251642.3
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_+_86511569 0.31 ENST00000441050.1
protease, serine, 23
chr6_+_158244223 0.31 ENST00000392185.3
sorting nexin 9
chr14_+_74417192 0.30 ENST00000554320.1
coenzyme Q6 monooxygenase
chr13_-_50018140 0.29 ENST00000410043.1
ENST00000347776.5
calcium binding protein 39-like
chr3_+_113666748 0.29 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr1_-_36615051 0.28 ENST00000373163.1
trafficking protein particle complex 3
chr15_+_42696954 0.28 ENST00000337571.4
ENST00000569136.1
calpain 3, (p94)
chr19_+_47759716 0.28 ENST00000221922.6
coiled-coil domain containing 9
chr16_-_79634595 0.28 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr11_+_86511549 0.27 ENST00000533902.2
protease, serine, 23
chr10_+_105036909 0.26 ENST00000369849.4
internexin neuronal intermediate filament protein, alpha
chr1_-_67896009 0.25 ENST00000370990.5
SERPINE1 mRNA binding protein 1
chr16_-_30538079 0.25 ENST00000562803.1
zinc finger protein 768
chr6_+_49431073 0.25 ENST00000335783.3
centromere protein Q
chr19_-_39421377 0.25 ENST00000430193.3
ENST00000600042.1
ENST00000221431.6
seryl-tRNA synthetase 2, mitochondrial
chr1_+_110754094 0.24 ENST00000369787.3
ENST00000413138.3
ENST00000438661.2
potassium voltage-gated channel, Shaw-related subfamily, member 4
chr8_-_94928861 0.23 ENST00000607097.1
microRNA 378d-2
chr21_-_38445470 0.23 ENST00000399098.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_+_4046964 0.22 ENST00000573984.1
cytochrome b5 domain containing 2
chr7_+_102937869 0.22 ENST00000249269.4
ENST00000428154.1
ENST00000420236.2
peptidase (mitochondrial processing) beta
chr14_-_25479811 0.22 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr1_-_67896069 0.20 ENST00000370995.2
ENST00000361219.6
SERPINE1 mRNA binding protein 1
chr5_-_115177247 0.20 ENST00000500945.2
autophagy related 12
chr1_-_36615065 0.20 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
trafficking protein particle complex 3
chrX_+_153237740 0.19 ENST00000369982.4
transmembrane protein 187
chr15_+_42697018 0.18 ENST00000397204.4
calpain 3, (p94)
chr3_+_46742823 0.18 ENST00000326431.3
transmembrane inner ear
chr21_-_38445011 0.17 ENST00000464265.1
ENST00000399102.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr19_-_39881669 0.17 ENST00000221266.7
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr19_+_50354430 0.17 ENST00000599732.1
prostate tumor overexpressed 1
chr15_-_77363513 0.17 ENST00000267970.4
tetraspanin 3
chr11_-_63439013 0.17 ENST00000398868.3
atlastin GTPase 3
chrX_-_74145273 0.17 ENST00000055682.6
KIAA2022
chrX_+_47867194 0.16 ENST00000376940.3
sperm acrosome associated 5
chr10_+_76586348 0.16 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
K(lysine) acetyltransferase 6B
chr19_-_5791215 0.16 ENST00000320699.8
ENST00000309061.7
dihydrouridine synthase 3-like (S. cerevisiae)
chr4_-_83295103 0.16 ENST00000313899.7
ENST00000352301.4
ENST00000509107.1
ENST00000353341.4
ENST00000541060.1
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
chr9_-_111696340 0.15 ENST00000374647.5
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr1_+_43148059 0.14 ENST00000321358.7
ENST00000332220.6
Y box binding protein 1
chr12_+_52281744 0.14 ENST00000301190.6
ENST00000538991.1
ankyrin repeat domain 33
chrX_-_68385274 0.14 ENST00000374584.3
ENST00000590146.1
praja ring finger 1, E3 ubiquitin protein ligase
chr18_-_12657988 0.13 ENST00000410092.3
ENST00000409402.4
spire-type actin nucleation factor 1
chr1_+_43148625 0.13 ENST00000436427.1
Y box binding protein 1
chr10_+_35416223 0.13 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
cAMP responsive element modulator
chr2_+_74361599 0.13 ENST00000401851.1
MGC10955
chr9_+_111696664 0.13 ENST00000374624.3
ENST00000445175.1
family with sequence similarity 206, member A
chr22_-_19929321 0.13 ENST00000400519.1
ENST00000535882.1
ENST00000334363.9
ENST00000400521.1
thioredoxin reductase 2
chr4_+_71570430 0.12 ENST00000417478.2
RUN and FYVE domain containing 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZBTB4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002125 maternal aggressive behavior(GO:0002125) positive regulation of female receptivity(GO:0045925)
0.8 3.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.7 5.8 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.6 1.9 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.5 3.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 4.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.3 2.2 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.3 1.6 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 1.1 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 2.7 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 2.5 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.2 0.9 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.2 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 1.5 GO:1990834 response to odorant(GO:1990834)
0.1 1.0 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.1 0.7 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.8 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.6 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.4 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 3.6 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.9 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 1.4 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 1.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.1 0.9 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 3.6 GO:0051764 actin crosslink formation(GO:0051764)
0.1 2.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 0.4 GO:0014735 regulation of muscle atrophy(GO:0014735) response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.7 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.1 1.0 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.8 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 1.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.6 GO:0046465 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.9 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:1904585 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.8 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 1.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.6 GO:0097264 self proteolysis(GO:0097264)
0.0 2.1 GO:0030261 chromosome condensation(GO:0030261)
0.0 0.9 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.8 GO:0002003 angiotensin maturation(GO:0002003)
0.0 0.9 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.9 GO:0030818 negative regulation of cAMP biosynthetic process(GO:0030818)
0.0 0.9 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.5 GO:0014877 response to stimulus involved in regulation of muscle adaptation(GO:0014874) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 4.2 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 1.1 GO:0048011 cellular response to hepatocyte growth factor stimulus(GO:0035729) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.0 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.7 GO:0045821 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.0 0.5 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.5 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 1.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 1.0 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.0 0.1 GO:0040038 polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 1.9 GO:0060563 neuroepithelial cell differentiation(GO:0060563)
0.0 1.0 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.3 5.8 GO:0097418 neurofibrillary tangle(GO:0097418)
0.1 1.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.5 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.8 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 2.8 GO:0000786 nucleosome(GO:0000786)
0.0 5.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.9 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.3 GO:0005883 neurofilament(GO:0005883)
0.0 0.9 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 2.0 GO:0043195 terminal bouton(GO:0043195)
0.0 1.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 2.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.5 GO:0002054 nucleobase binding(GO:0002054) dihydropyrimidinase activity(GO:0004157)
0.3 2.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 5.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.2 1.9 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 0.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 5.8 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 2.6 GO:0046870 cadmium ion binding(GO:0046870)
0.2 1.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.6 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.9 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 3.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.3 GO:0031419 cobalamin binding(GO:0031419)
0.1 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 1.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 2.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.9 GO:0031402 sodium ion binding(GO:0031402)
0.1 1.0 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.9 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 1.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.8 GO:0017166 vinculin binding(GO:0017166)
0.0 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.0 1.0 GO:0047617 very long-chain fatty acid-CoA ligase activity(GO:0031957) acyl-CoA hydrolase activity(GO:0047617)
0.0 1.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 1.1 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.9 GO:0071949 FAD binding(GO:0071949)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.9 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.0 0.7 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 5.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 3.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.3 PID SHP2 PATHWAY SHP2 signaling
0.0 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 4.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression