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Illumina Body Map 2
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Results for ZBTB6
Z-value: 1.88
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Transcription factors associated with ZBTB6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZBTB6 | hg19_v2_chr9_-_125675576_125675612 | 0.41 | 2.1e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZBTB6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 16.7 | GO:1990262 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 1.2 | 15.4 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.2 | 14.7 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.3 | 11.7 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.2 | 11.7 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.2 | 10.3 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.2 | 8.8 | GO:0048713 | regulation of oligodendrocyte differentiation(GO:0048713) |
| 0.3 | 8.3 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 7.8 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.8 | 7.4 | GO:0007506 | gonadal mesoderm development(GO:0007506) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 35.3 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.1 | 19.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 14.2 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.1 | 12.3 | GO:0044306 | neuron projection terminus(GO:0044306) |
| 0.1 | 11.7 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 10.2 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.3 | 9.8 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.2 | 7.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.1 | 7.5 | GO:0034705 | potassium channel complex(GO:0034705) |
| 0.0 | 7.5 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 14.7 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 12.3 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 11.4 | GO:0015144 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.2 | 8.5 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.0 | 8.3 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.7 | 7.9 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 7.4 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 7.1 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 6.4 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.3 | 6.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 15.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 5.7 | PID SYNDECAN 1 PATHWAY | Syndecan-1-mediated signaling events |
| 0.1 | 5.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 4.7 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 4.7 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.1 | 4.3 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 3.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 0.0 | 3.6 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 3.5 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 3.2 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 14.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 11.2 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.3 | 6.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.1 | 6.2 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.1 | 5.9 | REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE | Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline |
| 0.2 | 5.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 0.1 | 4.9 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 4.6 | REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors |
| 0.3 | 4.4 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.1 | 4.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |