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Illumina Body Map 2
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Results for ZNF263
Z-value: 1.43
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Transcription factors associated with ZNF263
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF263 | hg19_v2_chr16_+_3333443_3333545 | -0.08 | 6.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF263
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 9.0 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.2 | 7.7 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.3 | 7.2 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 6.5 | GO:0032291 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 0.5 | 6.3 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.6 | 5.0 | GO:0031444 | slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 1.2 | 4.9 | GO:0060254 | regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060) |
| 0.6 | 4.9 | GO:2000860 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
| 1.1 | 4.6 | GO:0072134 | nephrogenic mesenchyme morphogenesis(GO:0072134) allantois development(GO:1905069) |
| 0.3 | 4.2 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 12.5 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 10.6 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.1 | 10.0 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 9.6 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 8.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 8.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 7.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 7.2 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 6.8 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.1 | 6.6 | GO:0031941 | filamentous actin(GO:0031941) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 13.1 | GO:0005518 | collagen binding(GO:0005518) |
| 0.5 | 8.2 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.5 | 7.4 | GO:0035374 | chondroitin sulfate binding(GO:0035374) |
| 0.3 | 6.8 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 6.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.7 | 6.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.3 | 5.4 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.4 | 5.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.0 | 5.2 | GO:0005539 | glycosaminoglycan binding(GO:0005539) |
| 0.0 | 5.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 16.5 | NABA CORE MATRISOME | Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans |
| 0.0 | 10.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 10.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 8.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 8.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 5.2 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.2 | 3.7 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 3.4 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.1 | 3.3 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 3.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.1 | 7.6 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.2 | 7.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 7.1 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 6.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 5.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.2 | 4.8 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 4.5 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.1 | 4.1 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.1 | 3.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |