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Illumina Body Map 2

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Results for ZNF35

Z-value: 0.68

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Transcription factors associated with ZNF35

Gene Symbol Gene ID Gene Info
ZNF35
ENSG00000169981.6 zinc finger protein 35

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZNF35hg19_v2_chr3_+_44690211_446902670.125.3e-01Click!

Activity profile of ZNF35 motif

Sorted Z-values of ZNF35 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_148939598 1.49 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr3_-_148939835 1.44 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr16_-_77465450 1.03 ENST00000562345.1
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr10_+_74653330 0.98 ENST00000334011.5
OIT3
oncoprotein induced transcript 3
chr6_-_135271219 0.87 ENST00000367847.2
ENST00000367845.2
ALDH8A1
aldehyde dehydrogenase 8 family, member A1
chr7_-_83824449 0.85 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr7_-_83824169 0.80 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_+_70796784 0.73 ENST00000246891.4
ENST00000444405.3
CSN1S1
casein alpha s1
chr8_-_95274536 0.71 ENST00000297596.2
ENST00000396194.2
GEM
GTP binding protein overexpressed in skeletal muscle
chr10_-_52645416 0.71 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr13_-_36429763 0.68 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr10_-_131762105 0.65 ENST00000368648.3
ENST00000355311.5
EBF3
early B-cell factor 3
chr2_+_177015122 0.64 ENST00000468418.3
HOXD3
homeobox D3
chr4_+_68424434 0.64 ENST00000265404.2
ENST00000396225.1
STAP1
signal transducing adaptor family member 1
chr12_-_22487618 0.61 ENST00000404299.3
ENST00000396037.4
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr9_-_13432977 0.57 ENST00000605459.1
RP11-536O18.2
RP11-536O18.2
chr2_-_151395525 0.57 ENST00000439275.1
RND3
Rho family GTPase 3
chr1_+_84630574 0.53 ENST00000413538.1
ENST00000417530.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_79258444 0.50 ENST00000261205.4
SYT1
synaptotagmin I
chr12_+_25205446 0.49 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP
lymphoid-restricted membrane protein
chr12_+_54891495 0.49 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr1_+_214161272 0.46 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chr15_+_69857515 0.46 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr9_+_42671887 0.45 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr1_-_12677714 0.44 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr7_-_87342564 0.44 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr6_-_66417107 0.40 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr9_-_16705069 0.39 ENST00000471301.2
BNC2
basonuclin 2
chr10_-_52645379 0.38 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr12_-_22487588 0.38 ENST00000381424.3
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr4_-_186696561 0.38 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr12_+_25205666 0.36 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr4_-_89744365 0.36 ENST00000513837.1
ENST00000503556.1
FAM13A
family with sequence similarity 13, member A
chr7_+_80231466 0.35 ENST00000309881.7
ENST00000534394.1
CD36
CD36 molecule (thrombospondin receptor)
chr12_-_102872317 0.35 ENST00000424202.2
IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_-_58523010 0.33 ENST00000459701.2
ENST00000302819.5
ACOX2
acyl-CoA oxidase 2, branched chain
chr15_+_96876340 0.32 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_80531399 0.31 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr1_+_61869748 0.30 ENST00000357977.5
NFIA
nuclear factor I/A
chr9_-_5084580 0.29 ENST00000601793.1
AL161450.1
Uncharacterized protein
chrX_-_19905577 0.29 ENST00000379697.3
SH3KBP1
SH3-domain kinase binding protein 1
chr7_-_78400598 0.27 ENST00000536571.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_109248500 0.27 ENST00000356711.2
MYO16
myosin XVI
chr3_-_49967292 0.26 ENST00000455683.2
MON1A
MON1 secretory trafficking family member A
chr4_+_78804393 0.25 ENST00000502384.1
MRPL1
mitochondrial ribosomal protein L1
chr5_+_139027877 0.24 ENST00000302517.3
CXXC5
CXXC finger protein 5
chr12_+_51318513 0.24 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr6_+_32812568 0.24 ENST00000414474.1
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr17_+_75369400 0.24 ENST00000590059.1
SEPT9
septin 9
chrM_+_4431 0.24 ENST00000361453.3
MT-ND2
mitochondrially encoded NADH dehydrogenase 2
chr13_-_47471155 0.23 ENST00000543956.1
ENST00000542664.1
HTR2A
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr10_-_4285923 0.23 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr12_-_11091862 0.21 ENST00000537503.1
TAS2R14
taste receptor, type 2, member 14
chr6_+_76599809 0.21 ENST00000430435.1
MYO6
myosin VI
chr4_+_129730947 0.21 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr12_+_25205155 0.20 ENST00000550945.1
LRMP
lymphoid-restricted membrane protein
chr9_+_130853715 0.20 ENST00000373066.5
ENST00000432073.2
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_+_35553045 0.20 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr7_+_27282319 0.19 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr5_+_139028510 0.19 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC5
CXXC finger protein 5
chr19_-_13617247 0.19 ENST00000573710.2
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr5_-_39203093 0.18 ENST00000515010.1
FYB
FYN binding protein
chr16_-_8622226 0.18 ENST00000568335.1
TMEM114
transmembrane protein 114
chr21_-_42219065 0.18 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr15_-_76352069 0.16 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr1_-_169599353 0.16 ENST00000367793.2
ENST00000367794.2
ENST00000367792.2
ENST00000367791.2
ENST00000367788.2
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr8_-_145754428 0.15 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
C8orf82
chromosome 8 open reading frame 82
chr1_+_220701456 0.15 ENST00000366918.4
ENST00000402574.1
MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_+_72509751 0.14 ENST00000515556.1
ENST00000513379.1
ENST00000427584.2
RP11-60A8.1
RP11-60A8.1
chr8_+_85095769 0.13 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr3_-_49066811 0.12 ENST00000442157.1
ENST00000326739.4
IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr7_-_78400364 0.12 ENST00000535697.1
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_68339648 0.11 ENST00000479830.2
CTC-498J12.1
CTC-498J12.1
chr1_-_161008697 0.08 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr6_-_133084580 0.07 ENST00000525270.1
ENST00000530536.1
ENST00000524919.1
VNN2
vanin 2
chr17_-_42295870 0.06 ENST00000526094.1
ENST00000529383.1
ENST00000530828.1
UBTF
upstream binding transcription factor, RNA polymerase I
chr17_-_295730 0.05 ENST00000329099.4
FAM101B
family with sequence similarity 101, member B
chr19_-_56343353 0.04 ENST00000592953.1
ENST00000589093.1
NLRP11
NLR family, pyrin domain containing 11
chr4_+_88754113 0.04 ENST00000560249.1
ENST00000540395.1
ENST00000511670.1
ENST00000361056.3
MEPE
matrix extracellular phosphoglycoprotein
chr3_+_10157276 0.03 ENST00000530758.1
ENST00000256463.6
BRK1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr10_-_4285835 0.03 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr3_+_29323043 0.03 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr19_-_12833164 0.02 ENST00000356861.5
TNPO2
transportin 2
chr18_+_39535152 0.02 ENST00000262039.4
ENST00000398870.3
ENST00000586545.1
PIK3C3
phosphatidylinositol 3-kinase, catalytic subunit type 3
chr4_+_88754069 0.02 ENST00000395102.4
ENST00000497649.2
MEPE
matrix extracellular phosphoglycoprotein
chr15_+_35270552 0.01 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr20_+_56964169 0.01 ENST00000475243.1
VAPB
VAMP (vesicle-associated membrane protein)-associated protein B and C

Network of associatons between targets according to the STRING database.

First level regulatory network of ZNF35

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.6 GO:1903980 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) positive regulation of microglial cell activation(GO:1903980)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 2.9 GO:0006825 copper ion transport(GO:0006825)
0.1 1.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.4 GO:0001834 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.6 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.4 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.5 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 1.0 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.4 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.4 GO:2000332 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 1.0 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0072189 ureter development(GO:0072189)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.5 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.4 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.7 GO:0051233 spindle midzone(GO:0051233)
0.0 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.9 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.5 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.4 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol