Motif ID: AAAGUGC

Z-value: 1.746


Mature miRNA associated with seed AAAGUGC:

NamemiRBase Accession
hsa-miR-106a MIMAT0000103
hsa-miR-106b MIMAT0000680
hsa-miR-17 MIMAT0000070
hsa-miR-20a MIMAT0000075
hsa-miR-20b MIMAT0001413
hsa-miR-519d MIMAT0002853
hsa-miR-93 MIMAT0000093



Activity profile for motif AAAGUGC.

activity profile for motif AAAGUGC


Sorted Z-values histogram for motif AAAGUGC

Sorted Z-values for motif AAAGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAAGUGC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_204380903 49.622 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr18_+_21594349 49.615 NM_001135993
NM_001243425
 TTC39C

tetratricopeptide repeat domain 39C

chr14_+_92790151 38.170 NM_153646
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_-_61469322 36.749 NM_194298
 LOC100129721
SLC16A9
uncharacterized LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr14_+_92789536 33.744 NM_153647
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr18_+_21572736 33.601 NM_153211
 TTC39C
tetratricopeptide repeat domain 39C
chr11_-_113746205 31.267 NM_020886
 USP28
ubiquitin specific peptidase 28
chr18_-_13726582 27.767 NM_001098801
NM_152352
 FAM210A

family with sequence similarity 210, member A

chr14_+_92788924 26.548 NM_153648
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chrX_-_54384436 25.623 NM_001002838
NM_020922
 WNK3

WNK lysine deficient protein kinase 3

chr8_+_26435339 23.881 NM_001386
 DPYSL2
dihydropyrimidinase-like 2
chr2_+_10183630 23.851 NM_003597
NM_001177716
 KLF11

Kruppel-like factor 11

chr2_+_203499819 22.221 NM_173511
 FAM117B
family with sequence similarity 117, member B
chr19_-_49944613 21.537 NM_020309
 SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr12_-_16760935 21.043 NM_001001395
NM_001243609
 LMO3

LIM domain only 3 (rhombotin-like 2)

chr13_+_113623496 20.890 NM_001112732
 MCF2L
MCF.2 cell line derived transforming sequence-like
chr4_+_7045142 20.797 NM_152293
 TADA2B
transcriptional adaptor 2B
chr10_-_120514669 20.150 NM_153810
 C10orf46
chromosome 10 open reading frame 46
chr14_-_45431121 19.818 NM_017658
 KLHL28
kelch-like 28 (Drosophila)
chr16_-_2264776 19.774 NM_001042371
 PGP
phosphoglycolate phosphatase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 105 entries
enrichment   p-value GO term description
13.69 3.09e-02 GO:0043550 regulation of lipid kinase activity
12.64 4.90e-02 GO:0045022 early endosome to late endosome transport
5.77 1.39e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
5.02 1.96e-02 GO:0046777 protein autophosphorylation
3.83 4.82e-06 GO:0046578 regulation of Ras protein signal transduction
3.55 4.96e-08 GO:0051056 regulation of small GTPase mediated signal transduction
3.48 2.83e-02 GO:0048511 rhythmic process
3.03 1.40e-04 GO:0006917 induction of apoptosis
3.03 1.50e-04 GO:0012502 induction of programmed cell death
2.98 1.71e-02 GO:0000165 MAPKKK cascade
2.83 1.62e-04 GO:0007243 intracellular protein kinase cascade
2.83 1.62e-04 GO:0023014 signal transduction via phosphorylation event
2.80 1.01e-07 GO:0007167 enzyme linked receptor protein signaling pathway
2.71 3.64e-08 GO:0006468 protein phosphorylation
2.65 1.91e-02 GO:0009894 regulation of catabolic process
2.63 6.87e-06 GO:0045893 positive regulation of transcription, DNA-dependent
2.59 8.33e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.57 5.98e-08 GO:0016310 phosphorylation
2.57 1.02e-02 GO:0007264 small GTPase mediated signal transduction
2.56 2.38e-02 GO:0007420 brain development

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
4.32 2.60e-02 GO:0033267 axon part
1.71 4.69e-03 GO:0005654 nucleoplasm
1.70 9.51e-03 GO:0031226 intrinsic to plasma membrane
1.70 1.04e-02 GO:0005887 integral to plasma membrane
1.53 3.98e-03 GO:0044459 plasma membrane part
1.53 2.38e-02 GO:0031981 nuclear lumen
1.36 2.07e-05 GO:0005634 nucleus
1.16 4.55e-05 GO:0005622 intracellular
1.16 1.46e-04 GO:0044424 intracellular part
1.07 1.16e-02 GO:0044464 cell part
1.07 1.18e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
14.94 4.00e-03 GO:0070411 I-SMAD binding
14.60 3.71e-02 GO:0051019 mitogen-activated protein kinase binding
13.84 1.57e-05 GO:0004709 MAP kinase kinase kinase activity
7.38 7.70e-05 GO:0004702 receptor signaling protein serine/threonine kinase activity
6.57 2.79e-03 GO:0046332 SMAD binding
6.44 1.04e-03 GO:0003707 steroid hormone receptor activity
6.09 1.80e-03 GO:0004879 ligand-dependent nuclear receptor activity
5.78 5.62e-06 GO:0005088 Ras guanyl-nucleotide exchange factor activity
5.59 3.38e-06 GO:0005057 receptor signaling protein activity
5.40 7.63e-04 GO:0005089 Rho guanyl-nucleotide exchange factor activity
4.58 1.04e-02 GO:0031625 ubiquitin protein ligase binding
4.55 1.26e-06 GO:0005085 guanyl-nucleotide exchange factor activity
4.46 1.33e-02 GO:0019199 transmembrane receptor protein kinase activity
3.92 4.38e-09 GO:0005083 small GTPase regulator activity
2.96 4.00e-07 GO:0030695 GTPase regulator activity
2.90 2.96e-06 GO:0004674 protein serine/threonine kinase activity
2.88 8.68e-07 GO:0060589 nucleoside-triphosphatase regulator activity
2.77 4.88e-08 GO:0004672 protein kinase activity
2.76 3.18e-03 GO:0008134 transcription factor binding
2.62 3.04e-08 GO:0016773 phosphotransferase activity, alcohol group as acceptor