Motif ID: AAGGCAC

Z-value: 2.639


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_116166346 45.913 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116164838 45.687 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116165043 45.010 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr10_-_33246786 43.579 NM_133376
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chrX_+_49028183 37.095 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr6_+_138725314 36.678 NM_014320
HEBP2
heme binding protein 2
chr10_-_33247178 35.638 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr10_+_17270257 35.281 NM_003380
VIM
vimentin
chr1_+_182992329 35.086 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr2_-_161350304 34.150 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_50143350 32.748 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr2_+_109204904 32.080 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr22_-_50746000 29.468 NM_012401
PLXNB2
plexin B2
chr2_+_109204745 28.824 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_120169493 28.805 NM_007085
FSTL1
follistatin-like 1
chr16_-_11680146 28.625 NM_004862
LITAF
lipopolysaccharide-induced TNF factor
chr2_-_64881040 28.622 NM_014755
SERTAD2
SERTA domain containing 2
chr5_+_172410762 28.491 NM_003945
ATP6V0E1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr7_+_98972281 28.180 NM_005720
ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr1_+_223900061 27.587 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr2_+_109223600 27.523 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109271267 26.704 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr6_-_13814546 26.676 NM_001031713
CCDC90A
coiled-coil domain containing 90A
chr7_-_137686814 26.308 NM_001253775
NM_194071
CREB3L2

cAMP responsive element binding protein 3-like 2

chr1_+_64088886 26.054 NM_001172818
PGM1
phosphoglucomutase 1
chr15_-_55562483 25.632 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr1_-_154943001 25.411 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr21_-_46293609 24.873 NM_004339
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr16_-_11680756 24.866 NM_001136472
NM_001136473
LITAF

lipopolysaccharide-induced TNF factor

chr2_+_109237679 24.836 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr4_-_122618140 24.502 NM_001154
ANXA5
annexin A5
chr3_-_195808958 24.162 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr21_-_44846927 24.143 NM_173354
SIK1
salt-inducible kinase 1
chr1_+_165796652 23.965 NM_012474
UCK2
uridine-cytidine kinase 2
chr3_+_187943192 23.921 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_-_195808997 23.842 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr2_-_37899227 23.683 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr12_-_65153189 23.306 NM_002076
GNS
glucosamine (N-acetyl)-6-sulfatase
chr12_-_15942350 23.278 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr1_+_223889253 23.190 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr6_-_7910716 23.167 NM_030810
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr2_+_178257371 22.936 NM_003659
AGPS
alkylglycerone phosphate synthase
chr11_+_832909 22.572 NM_001039490
NM_004357
NM_139029
NM_139030
CD151



CD151 molecule (Raph blood group)



chr6_-_52441815 22.442 NM_012288
TRAM2
translocation associated membrane protein 2
chr16_-_84651639 22.350 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr2_+_109150807 22.341 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr13_-_110959441 22.193 NM_001845
COL4A1
collagen, type IV, alpha 1
chr3_+_69812620 22.112 NM_001184967
MITF
microphthalmia-associated transcription factor
chr11_+_57529233 22.055 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chrX_-_109683457 21.988 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr8_+_110346549 21.851 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr12_-_58146118 21.845 NM_000075
CDK4
cyclin-dependent kinase 4
chr7_+_101460881 21.686 NM_181552
CUX1
cut-like homeobox 1
chr20_+_361272 21.467 NM_021158
TRIB3
tribbles homolog 3 (Drosophila)
chr2_-_153573858 21.359 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr7_+_77167351 21.227 NM_001131008
NM_001131009
PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr6_-_86351156 21.107 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr1_+_64058891 21.094 NM_002633
PGM1
phosphoglucomutase 1
chr10_-_74856656 20.917 NM_000917
NM_001017962
NM_001142595
NM_001142596
P4HA1



prolyl 4-hydroxylase, alpha polypeptide I



chr15_+_90931470 20.685 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr1_+_64059479 20.605 NM_001172819
PGM1
phosphoglucomutase 1
chr17_-_41174431 20.499 NM_006373
VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr22_-_36784055 20.314 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr10_-_3827418 20.297 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr6_-_109703703 20.258 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr19_+_797390 20.233 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr3_+_69812961 20.128 NM_006722
MITF
microphthalmia-associated transcription factor
chr15_-_55563091 20.104 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr6_-_7910278 19.976 NM_001145549
TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr5_-_10761344 19.930 NM_004394
DAP
death-associated protein
chr18_+_29078026 19.684 NM_001943
DSG2
desmoglein 2
chr3_+_187871473 19.656 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_167298280 19.652 NM_001198783
POU2F1
POU class 2 homeobox 1
chr7_+_17338182 19.592 NM_001621
AHR
aryl hydrocarbon receptor
chr17_+_28707495 19.555 NM_001199775
CPD
carboxypeptidase D
chr11_-_93276513 19.254 NM_020179
C11orf75
chromosome 11 open reading frame 75
chr2_-_3523345 19.239 NM_018269
ADI1
acireductone dioxygenase 1
chr5_-_98262217 19.152 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr9_+_114423849 18.821 NM_001017998
NM_001198664
GNG10

guanine nucleotide binding protein (G protein), gamma 10

chr1_-_225840660 18.758 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr7_+_66386129 18.718 NM_017994
C7orf42
chromosome 7 open reading frame 42
chr8_-_49833823 18.332 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr5_+_149340287 18.309 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr16_+_69220940 18.254 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr5_+_82767492 18.224 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr1_-_95392501 18.216 NM_001839
CNN3
calponin 3, acidic
chr19_+_39138265 17.831 NM_004924
ACTN4
actinin, alpha 4
chr15_-_55581969 17.714 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr17_+_28705922 17.696 NM_001304
CPD
carboxypeptidase D
chr10_+_81107219 17.639 NM_005729
PPIF
peptidylprolyl isomerase F
chr6_-_7313352 17.636 NM_003144
SSR1
signal sequence receptor, alpha
chr3_+_180630054 17.586 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr6_-_36515245 17.559 NM_007271
STK38
serine/threonine kinase 38
chrX_-_77150907 17.226 NM_032121
MAGT1
magnesium transporter 1
chrX_-_109561314 17.187 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr3_+_187930720 17.112 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_69915374 17.004 NM_198177
MITF
microphthalmia-associated transcription factor
chr2_-_174828775 16.977 NM_001017371
SP3
Sp3 transcription factor
chr8_-_102217868 16.956 NM_001042511
ZNF706
zinc finger protein 706
chr7_+_128379345 16.739 NM_001130674
NM_001199671
NM_001199672
NM_001199673
NM_001199674
NM_001219
CALU





calumenin





chr20_+_48552902 16.623 NM_018683
RNF114
ring finger protein 114
chr14_-_75643335 16.427 NM_006827
TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr8_-_102217907 16.421 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr4_+_169418167 16.407 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr3_+_152880024 16.394 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chr1_+_40723730 16.293 NM_005857
ZMPSTE24
zinc metallopeptidase (STE24 homolog, S. cerevisiae)
chr2_-_43453737 16.231 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr5_+_65440004 16.206 NM_001077199
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr3_+_69788562 16.199 NM_198159
MITF
microphthalmia-associated transcription factor
chr3_-_141747434 16.112 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr8_+_98656329 15.998 NM_178812
MTDH
metadherin
chr5_+_65440662 15.994 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chrX_-_10544852 15.950 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr6_+_7107986 15.732 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr1_-_154946859 15.594 NM_001130041
NM_001202859
NM_003029
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chr10_-_30024594 15.593 NM_003174
SVIL
supervillin
chr10_-_27443309 15.581 NM_001253866
NM_014263
NM_139312
YME1L1


YME1-like 1 (S. cerevisiae)


chrX_-_106243442 15.425 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr1_-_27816676 15.351 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr5_+_102201526 15.348 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr5_-_133968463 15.225 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr15_-_101792125 15.119 NM_014918
CHSY1
chondroitin sulfate synthase 1
chr8_-_37756971 15.080 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr7_+_142960502 15.053 NM_001143679
NM_001143680
NM_001143681
NM_015917
GSTK1



glutathione S-transferase kappa 1



chr3_+_37903643 15.027 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr5_-_137878915 15.021 NM_004730
ETF1
eukaryotic translation termination factor 1
chr17_-_47439326 14.996 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chr4_-_185747183 14.996 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr20_-_43977023 14.859 NM_002999
SDC4
syndecan 4
chr10_+_51576284 14.835 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr1_+_180123906 14.624 NM_001004128
NM_002826
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr2_+_69969105 14.579 NM_001153
ANXA4
annexin A4
chr1_+_7831326 14.511 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr1_+_116184573 14.445 NM_001172411
NM_138959
VANGL1

vang-like 1 (van gogh, Drosophila)

chr7_-_6523689 14.340 NM_001100603
NM_006854
KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr9_+_71819926 14.300 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr1_+_110091185 14.198 NM_006496
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr22_+_21996541 14.157 NM_022044
SDF2L1
stromal cell-derived factor 2-like 1
chr20_+_61569358 14.108 NM_017896
C20orf11
chromosome 20 open reading frame 11
chr11_+_19734821 14.107 NM_001244963
NM_145117
NM_182964
NAV2


neuron navigator 2


chr1_-_55352920 14.005 NM_014762
DHCR24
24-dehydrocholesterol reductase
chr12_-_58240746 13.953 NM_005730
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr17_+_52978022 13.905 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr10_+_72575623 13.816 NM_003901
SGPL1
sphingosine-1-phosphate lyase 1
chr14_+_70078309 13.794 NM_014734
KIAA0247
KIAA0247
chr7_-_105752974 13.695 NM_006754
SYPL1
synaptophysin-like 1
chr4_-_54930771 13.667 NM_012110
CHIC2
cysteine-rich hydrophobic domain 2
chr10_+_51565107 13.632 NM_001145260
NM_001145261
NM_001145263
NCOA4


nuclear receptor coactivator 4


chr10_+_89419352 13.577 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr11_-_17191287 13.566 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chrX_-_10588458 13.562 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr6_-_134639195 13.544 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_40540491 13.478 NM_003150
NM_139276
STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

chrX_-_73834460 13.386 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr3_-_10362837 13.362 NM_183352
SEC13
SEC13 homolog (S. cerevisiae)
chr14_-_35099296 13.287 NM_021249
NM_152233
SNX6

sorting nexin 6

chr7_+_2394428 13.261 NM_001037283
NM_003751
EIF3B

eukaryotic translation initiation factor 3, subunit B

chr7_-_105752718 13.223 NM_182715
SYPL1
synaptophysin-like 1
chr1_-_86174088 13.165 NM_001170670
NM_017953
ZNHIT6

zinc finger, HIT-type containing 6

chr4_+_169753105 13.153 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr10_-_33224485 13.103 NM_033668
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr6_+_35995453 13.087 NM_001315
NM_139012
NM_139013
NM_139014
MAPK14



mitogen-activated protein kinase 14



chrX_-_10645726 13.086 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr1_+_16767166 13.068 NM_001145277
NM_001145278
NM_018090
NECAP2


NECAP endocytosis associated 2


chr6_+_143929316 13.068 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr7_-_105162551 12.913 NM_019042
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr8_-_145018904 12.854 NM_201381
PLEC
plectin
chr6_-_134498973 12.848 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr16_-_85832900 12.841 NM_001142288
NM_006067
COX4NB

COX4 neighbor

chr17_+_7123149 12.825 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr11_+_60681370 12.700 NM_024092
TMEM109
transmembrane protein 109
chr1_-_150947456 12.695 NM_022075
NM_181746
CERS2

ceramide synthase 2

chr10_-_14372807 12.688 NM_018027
FRMD4A
FERM domain containing 4A
chr3_-_10362724 12.643 NM_001136232
SEC13
SEC13 homolog (S. cerevisiae)
chr17_-_80376436 12.636 NM_024648
NM_175902
C17orf101

chromosome 17 open reading frame 101

chr7_+_77166750 12.494 NM_002835
PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr1_+_116185249 12.481 NM_001172412
VANGL1
vang-like 1 (van gogh, Drosophila)
chr2_-_174830429 12.471 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr15_+_45315301 12.424 NM_003104
SORD
sorbitol dehydrogenase
chr17_-_40540359 12.298 NM_213662
STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chrX_+_131157635 12.233 NM_001042452
MST4
serine/threonine protein kinase MST4
chr4_+_169552752 12.231 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr4_+_77870864 12.228 NM_018243
SEPT11
septin 11
chr20_+_62496580 12.192 NM_001243891
NM_001243892
NM_001243894
NM_001243895
NM_003288
NM_199359
NM_199360
NM_199361
NM_199362
NM_199363
TPD52L2









tumor protein D52-like 2









chr9_-_33167355 12.154 NM_001497
B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr5_-_142783975 12.120 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr16_-_85045119 12.106 NM_001145548
NM_017740
ZDHHC7

zinc finger, DHHC-type containing 7

chr8_+_98881277 12.063 NM_002380
NM_030583
MATN2

matrilin 2

chr17_-_882905 11.908 NM_022463
NXN
nucleoredoxin
chr10_+_51572363 11.906 NM_005437
NCOA4
nuclear receptor coactivator 4
chr11_+_46403205 11.891 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr17_-_79828691 11.887 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr1_+_32645322 11.857 NM_175852
TXLNA
taxilin alpha
chr13_-_50367027 11.854 NM_002267
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr6_+_20402040 11.849 NM_001949
E2F3
E2F transcription factor 3
chr6_-_86352982 11.822 NM_001159677
NM_006372
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr11_+_46403302 11.802 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr1_+_236958539 11.684 NM_000254
MTR
5-methyltetrahydrofolate-homocysteine methyltransferase
chr17_+_57970442 11.569 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr10_-_75173807 11.515 NM_001156
NM_004034
ANXA7

annexin A7


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 8.63e-17 GO:0009987 cellular process
1.37 4.02e-09 GO:0044237 cellular metabolic process
2.93 4.76e-09 GO:0061024 membrane organization
2.89 1.34e-08 GO:0016044 cellular membrane organization
1.63 5.97e-08 GO:0048518 positive regulation of biological process
1.65 2.19e-07 GO:0048522 positive regulation of cellular process
1.42 7.73e-07 GO:0044260 cellular macromolecule metabolic process
1.29 1.68e-06 GO:0008152 metabolic process
1.29 1.74e-06 GO:0050794 regulation of cellular process
1.31 1.79e-06 GO:0044238 primary metabolic process
1.26 2.40e-06 GO:0065007 biological regulation
1.87 3.69e-06 GO:0033036 macromolecule localization
2.15 7.58e-06 GO:0046907 intracellular transport
1.36 1.04e-05 GO:0043170 macromolecule metabolic process
1.61 2.97e-05 GO:0048523 negative regulation of cellular process
1.26 2.97e-05 GO:0050789 regulation of biological process
1.41 3.99e-05 GO:0019222 regulation of metabolic process
2.11 4.60e-05 GO:0016192 vesicle-mediated transport
1.44 5.09e-05 GO:0051179 localization
1.45 5.24e-05 GO:0016043 cellular component organization
1.45 7.06e-05 GO:0060255 regulation of macromolecule metabolic process
1.47 1.37e-04 GO:0006810 transport
1.42 1.40e-04 GO:0031323 regulation of cellular metabolic process
1.43 1.42e-04 GO:0071840 cellular component organization or biogenesis
1.42 2.05e-04 GO:0080090 regulation of primary metabolic process
1.46 2.33e-04 GO:0051234 establishment of localization
2.29 2.53e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.53 2.80e-04 GO:0048519 negative regulation of biological process
1.82 3.27e-04 GO:0051649 establishment of localization in cell
1.94 3.55e-04 GO:0045184 establishment of protein localization
1.95 3.96e-04 GO:0015031 protein transport
2.10 5.58e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.82 6.09e-04 GO:0008104 protein localization
1.74 7.06e-04 GO:0051641 cellular localization
1.40 9.12e-04 GO:0007275 multicellular organismal development
1.37 9.88e-04 GO:0032502 developmental process
1.84 1.22e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.40 1.67e-03 GO:0006807 nitrogen compound metabolic process
1.71 1.92e-03 GO:0009893 positive regulation of metabolic process
10.64 3.18e-03 GO:0032365 intracellular lipid transport
1.42 3.96e-03 GO:0048731 system development
2.81 4.68e-03 GO:0048011 nerve growth factor receptor signaling pathway
1.46 6.63e-03 GO:0044249 cellular biosynthetic process
1.38 7.89e-03 GO:0048856 anatomical structure development
1.60 8.31e-03 GO:0009653 anatomical structure morphogenesis
3.59 1.03e-02 GO:0016197 endosome transport
1.44 1.04e-02 GO:0009058 biosynthetic process
1.43 1.06e-02 GO:0010468 regulation of gene expression
2.68 1.11e-02 GO:0006897 endocytosis
2.68 1.11e-02 GO:0010324 membrane invagination
1.37 1.60e-02 GO:0034641 cellular nitrogen compound metabolic process
1.66 1.62e-02 GO:0031325 positive regulation of cellular metabolic process
1.67 1.96e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.40 2.16e-02 GO:0009889 regulation of biosynthetic process
3.40 2.18e-02 GO:0007265 Ras protein signal transduction
1.40 2.43e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 2.56e-02 GO:0023052 signaling
1.40 2.84e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.18 3.09e-02 GO:0006790 sulfur compound metabolic process
1.34 3.24e-02 GO:0007165 signal transduction
1.83 3.25e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.41 3.41e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.42 3.47e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.06 3.83e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.87 3.83e-02 GO:0010628 positive regulation of gene expression
1.45 3.83e-02 GO:0048869 cellular developmental process
1.67 4.23e-02 GO:0010941 regulation of cell death
1.91 4.29e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.39 4.38e-02 GO:0031326 regulation of cellular biosynthetic process
1.46 4.51e-02 GO:0030154 cell differentiation
1.29 4.98e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.74e-16 GO:0044424 intracellular part
1.35 2.89e-16 GO:0005737 cytoplasm
1.22 2.72e-15 GO:0005622 intracellular
1.42 3.86e-13 GO:0044444 cytoplasmic part
1.26 1.35e-12 GO:0043226 organelle
1.26 3.07e-12 GO:0043229 intracellular organelle
1.27 1.48e-10 GO:0043227 membrane-bounded organelle
1.27 2.08e-10 GO:0043231 intracellular membrane-bounded organelle
1.69 4.82e-08 GO:0005829 cytosol
1.34 3.83e-07 GO:0044422 organelle part
1.33 7.60e-07 GO:0044446 intracellular organelle part
1.62 1.45e-06 GO:0031090 organelle membrane
1.70 8.01e-06 GO:0012505 endomembrane system
2.04 1.43e-05 GO:0031410 cytoplasmic vesicle
2.00 2.15e-05 GO:0031982 vesicle
2.00 8.01e-05 GO:0031988 membrane-bounded vesicle
1.97 2.06e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.07 5.26e-04 GO:0044464 cell part
1.07 5.37e-04 GO:0005623 cell
1.82 1.21e-03 GO:0005626 insoluble fraction
2.12 2.36e-03 GO:0005768 endosome
1.70 4.02e-03 GO:0005794 Golgi apparatus
1.76 6.72e-03 GO:0005624 membrane fraction
1.63 8.75e-03 GO:0000267 cell fraction
1.43 9.55e-03 GO:0044428 nuclear part
2.87 1.90e-02 GO:0005769 early endosome
1.22 2.41e-02 GO:0005634 nucleus
1.73 2.44e-02 GO:0044432 endoplasmic reticulum part
1.59 2.71e-02 GO:0005783 endoplasmic reticulum
1.76 2.96e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
2.31 3.20e-02 GO:0010008 endosome membrane
1.17 3.26e-02 GO:0016020 membrane
2.29 3.64e-02 GO:0044440 endosomal part
7.20 3.86e-02 GO:0005811 lipid particle
3.19 3.95e-02 GO:0030133 transport vesicle
2.63 4.05e-02 GO:0070161 anchoring junction
3.33 4.42e-02 GO:0042470 melanosome
3.33 4.42e-02 GO:0048770 pigment granule

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.41 1.62e-17 GO:0005515 protein binding
1.20 4.64e-13 GO:0005488 binding
1.48 5.88e-04 GO:0000166 nucleotide binding
1.49 5.60e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.47 7.22e-03 GO:0032553 ribonucleotide binding
1.47 7.22e-03 GO:0032555 purine ribonucleotide binding
1.78 7.95e-03 GO:0016301 kinase activity
1.80 7.97e-03 GO:0019899 enzyme binding
1.47 9.27e-03 GO:0017076 purine nucleotide binding
2.08 9.38e-03 GO:0008289 lipid binding
1.95 1.06e-02 GO:0008092 cytoskeletal protein binding
15.19 2.51e-02 GO:0001085 RNA polymerase II transcription factor binding
2.55 2.89e-02 GO:0005543 phospholipid binding