Motif ID: AAGGCAC

Z-value: 2.639


Mature miRNA associated with seed AAGGCAC:

NamemiRBase Accession
hsa-miR-124 MIMAT0000422
hsa-miR-506 MIMAT0002878



Activity profile for motif AAGGCAC.

activity profile for motif AAGGCAC


Sorted Z-values histogram for motif AAGGCAC

Sorted Z-values for motif AAGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGCAC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_116166346 45.913 NM_001172896
NM_001172897
 CAV1

caveolin 1, caveolae protein, 22kDa

chr7_+_116164838 45.687 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_116165043 45.010 NM_001172895
 CAV1
caveolin 1, caveolae protein, 22kDa
chr10_-_33246786 43.579 NM_133376
 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chrX_+_49028183 37.095 NM_002668
 PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr6_+_138725314 36.678 NM_014320
 HEBP2
heme binding protein 2
chr10_-_33247178 35.638 NM_002211
 ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr10_+_17270257 35.281 NM_003380
 VIM
vimentin
chr1_+_182992329 35.086 NM_002293
 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr2_-_161350304 34.150 NM_002897
NM_016836
 RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_-_50143350 32.748 NM_006270
 RRAS
related RAS viral (r-ras) oncogene homolog
chr2_+_109204904 32.080 NM_001193488
 LIMS1
LIM and senescent cell antigen-like domains 1
chr22_-_50746000 29.468 NM_012401
 PLXNB2
plexin B2
chr2_+_109204745 28.824 NM_004987
 LIMS1
LIM and senescent cell antigen-like domains 1
chr3_-_120169493 28.805 NM_007085
 FSTL1
follistatin-like 1
chr16_-_11680146 28.625 NM_004862
 LITAF
lipopolysaccharide-induced TNF factor
chr2_-_64881040 28.622 NM_014755
 SERTAD2
SERTA domain containing 2
chr5_+_172410762 28.491 NM_003945
 ATP6V0E1
ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
chr7_+_98972281 28.180 NM_005720
 ARPC1B
actin related protein 2/3 complex, subunit 1B, 41kDa
chr1_+_223900061 27.587 NM_001748
 CAPN2
calpain 2, (m/II) large subunit

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 71 entries
enrichment   p-value GO term description
10.64 3.18e-03 GO:0032365 intracellular lipid transport
3.59 1.03e-02 GO:0016197 endosome transport
3.40 2.18e-02 GO:0007265 Ras protein signal transduction
3.18 3.09e-02 GO:0006790 sulfur compound metabolic process
2.93 4.76e-09 GO:0061024 membrane organization
2.89 1.34e-08 GO:0016044 cellular membrane organization
2.81 4.68e-03 GO:0048011 nerve growth factor receptor signaling pathway
2.68 1.11e-02 GO:0006897 endocytosis
2.68 1.11e-02 GO:0010324 membrane invagination
2.29 2.53e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.15 7.58e-06 GO:0046907 intracellular transport
2.11 4.60e-05 GO:0016192 vesicle-mediated transport
2.10 5.58e-04 GO:0007167 enzyme linked receptor protein signaling pathway
2.06 3.83e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.95 3.96e-04 GO:0015031 protein transport
1.94 3.55e-04 GO:0045184 establishment of protein localization
1.91 4.29e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.87 3.69e-06 GO:0033036 macromolecule localization
1.87 3.83e-02 GO:0010628 positive regulation of gene expression
1.84 1.22e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
7.20 3.86e-02 GO:0005811 lipid particle
3.33 4.42e-02 GO:0042470 melanosome
3.33 4.42e-02 GO:0048770 pigment granule
3.19 3.95e-02 GO:0030133 transport vesicle
2.87 1.90e-02 GO:0005769 early endosome
2.63 4.05e-02 GO:0070161 anchoring junction
2.31 3.20e-02 GO:0010008 endosome membrane
2.29 3.64e-02 GO:0044440 endosomal part
2.12 2.36e-03 GO:0005768 endosome
2.04 1.43e-05 GO:0031410 cytoplasmic vesicle
2.00 2.15e-05 GO:0031982 vesicle
2.00 8.01e-05 GO:0031988 membrane-bounded vesicle
1.97 2.06e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.82 1.21e-03 GO:0005626 insoluble fraction
1.76 6.72e-03 GO:0005624 membrane fraction
1.76 2.96e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.73 2.44e-02 GO:0044432 endoplasmic reticulum part
1.70 8.01e-06 GO:0012505 endomembrane system
1.70 4.02e-03 GO:0005794 Golgi apparatus
1.69 4.82e-08 GO:0005829 cytosol

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
15.19 2.51e-02 GO:0001085 RNA polymerase II transcription factor binding
2.55 2.89e-02 GO:0005543 phospholipid binding
2.08 9.38e-03 GO:0008289 lipid binding
1.95 1.06e-02 GO:0008092 cytoskeletal protein binding
1.80 7.97e-03 GO:0019899 enzyme binding
1.78 7.95e-03 GO:0016301 kinase activity
1.49 5.60e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.48 5.88e-04 GO:0000166 nucleotide binding
1.47 7.22e-03 GO:0032553 ribonucleotide binding
1.47 7.22e-03 GO:0032555 purine ribonucleotide binding
1.47 9.27e-03 GO:0017076 purine nucleotide binding
1.41 1.62e-17 GO:0005515 protein binding
1.20 4.64e-13 GO:0005488 binding