Motif ID: AAUCUCA

Z-value: 0.295


Mature miRNA associated with seed AAUCUCA:

NamemiRBase Accession
hsa-miR-216a MIMAT0000273



Activity profile for motif AAUCUCA.

activity profile for motif AAUCUCA


Sorted Z-values histogram for motif AAUCUCA

Sorted Z-values for motif AAUCUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_138428477 2.027 NM_022121
PERP
PERP, TP53 apoptosis effector
chr3_+_142342265 1.958 NM_002670
PLS1
plastin 1
chr3_+_142315205 1.874 NM_001145319
PLS1
plastin 1
chr3_+_142375738 1.854 NM_001172312
PLS1
plastin 1
chrX_-_20284708 1.269 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr2_+_178257371 1.239 NM_003659
AGPS
alkylglycerone phosphate synthase
chr4_+_175204827 1.093 NM_001040157
CEP44
centrosomal protein 44kDa
chr11_+_92085261 1.088 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chrX_-_109683457 0.959 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr1_-_53793743 0.956 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr3_-_42917632 0.859 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr3_+_172472246 0.857 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr12_-_2986299 0.856 NM_001243088
NM_001243089
NM_021953
NM_202002
NM_202003
FOXM1




forkhead box M1




chrX_-_109561314 0.828 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr4_+_99916787 0.824 NM_015143
METAP1
methionyl aminopeptidase 1
chrX_+_119738542 0.821 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr3_-_176915012 0.809 NM_024665
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr2_+_109204904 0.787 NM_001193488
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109204745 0.765 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_203776948 0.754 NM_018256
WDR12
WD repeat domain 12
chr13_-_31040035 0.749 NM_002128
HMGB1
high mobility group box 1
chr7_-_139876718 0.748 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_-_137549029 0.746 NM_004661
CDC23
cell division cycle 23 homolog (S. cerevisiae)
chr2_+_109223600 0.736 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_109150807 0.731 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_151344145 0.722 NM_005168
RND3
Rho family GTPase 3
chr2_+_109271267 0.703 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_119737743 0.682 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr5_+_112312392 0.679 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr5_-_148442606 0.676 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr1_-_67896098 0.675 NM_001018067
NM_001018068
NM_001018069
NM_015640
SERBP1



SERPINE1 mRNA binding protein 1



chr2_+_109237679 0.669 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_-_37544165 0.659 NM_005813
PRKD3
protein kinase D3
chr9_-_36258383 0.621 NM_001190383
NM_001190384
NM_005476
GNE


glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase


chr12_+_123237302 0.609 NM_003677
DENR
density-regulated protein
chr9_-_36276930 0.595 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr15_-_55562483 0.594 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr10_+_97803064 0.581 NM_001134375
NM_001134376
NM_019084
CCNJ


cyclin J


chr12_-_57030083 0.577 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr12_+_50344523 0.563 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr11_+_111944967 0.562 NM_001082969
NM_001082970
NM_018195
C11orf57


chromosome 11 open reading frame 57


chr3_+_170075449 0.558 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr8_+_48872762 0.536 NM_005914
NM_182746
MCM4

minichromosome maintenance complex component 4

chr9_+_71650478 0.518 NM_000144
NM_001161706
NM_181425
FXN


frataxin


chr15_+_48623616 0.514 NM_001025248
NM_001025249
DUT

deoxyuridine triphosphatase

chr15_-_55563091 0.511 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr15_-_55581969 0.509 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr16_-_4292052 0.501 NM_001098814
SRL
sarcalumenin
chr1_+_167298280 0.492 NM_001198783
POU2F1
POU class 2 homeobox 1
chr17_+_57970442 0.492 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr10_-_14372807 0.469 NM_018027
FRMD4A
FERM domain containing 4A
chr15_+_48624354 0.465 NM_001948
DUT
deoxyuridine triphosphatase
chr7_+_12250818 0.454 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr2_-_242212244 0.441 NM_001243900
NM_203346
HDLBP

high density lipoprotein binding protein

chr14_+_71374111 0.430 NM_014982
PCNX
pecanex homolog (Drosophila)
chr1_-_67520028 0.418 NM_015139
SLC35D1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr8_-_87520981 0.414 NM_016033
FAM82B
family with sequence similarity 82, member B
chr7_+_116502529 0.409 NM_006136
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr16_-_12010518 0.409 NM_001130007
GSPT1
G1 to S phase transition 1
chr1_+_166808721 0.405 NM_017542
POGK
pogo transposable element with KRAB domain
chr20_-_524335 0.396 NM_001895
NM_177559
NM_177560
CSNK2A1


casein kinase 2, alpha 1 polypeptide


chrX_-_111326003 0.385 NM_012471
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr1_-_109506016 0.379 NM_001048210
NM_015127
CLCC1

AKNAD1
chloride channel CLIC-like 1

AKNA domain containing 1
chr4_+_52709165 0.379 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chrX_-_10544852 0.378 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_203241044 0.377 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr3_-_64673330 0.370 NM_182920
ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr6_-_24666818 0.367 NM_016614
TDP2
tyrosyl-DNA phosphodiesterase 2
chr19_+_13105970 0.366 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr5_-_133968463 0.359 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr3_-_125094003 0.353 NM_021964
ZNF148
zinc finger protein 148
chrX_-_10588458 0.343 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr2_+_111878450 0.334 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr10_+_43277953 0.332 NM_014753
BMS1
BMS1 homolog, ribosome assembly protein (yeast)
chr12_+_27863705 0.332 NM_001190864
NM_021821
MRPS35

mitochondrial ribosomal protein S35

chr1_+_236686738 0.331 NM_006499
NM_201543
LGALS8

lectin, galactoside-binding, soluble, 8

chr20_+_56884749 0.330 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr5_+_68788118 0.328 NM_002538
OCLN
occludin
chr1_-_207205996 0.322 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr4_+_89299874 0.319 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr16_-_67840464 0.319 NM_020850
RANBP10
RAN binding protein 10
chr1_+_236681513 0.316 NM_201545
LGALS8
lectin, galactoside-binding, soluble, 8
chr7_-_122839999 0.313 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chrX_-_10645726 0.312 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr5_+_68788387 0.310 NM_001205254
OCLN
occludin
chr16_+_23568833 0.307 NM_019116
UBFD1
ubiquitin family domain containing 1
chr4_+_3076236 0.306 NM_002111
HTT
huntingtin
chr10_+_11206928 0.304 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr17_+_30677138 0.303 NM_001032293
NM_001098507
NM_003457
ZNF207


zinc finger protein 207


chr3_-_69129502 0.297 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr22_-_46933066 0.296 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chrX_+_67718623 0.295 NM_001195214
NM_173834
YIPF6

Yip1 domain family, member 6

chr8_+_67341244 0.293 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr14_+_32798478 0.293 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr1_-_68915631 0.291 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr16_-_12009804 0.280 NM_001130006
NM_002094
GSPT1

G1 to S phase transition 1

chr4_-_139163222 0.278 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_+_190105660 0.277 NM_006580
CLDN16
claudin 16
chr3_-_121264780 0.272 NM_199420
POLQ
polymerase (DNA directed), theta
chr13_-_76055872 0.271 NM_014832
TBC1D4
TBC1 domain family, member 4
chr1_-_6296034 0.271 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr1_+_167189948 0.266 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr22_-_24303317 0.260 NM_000854
NM_001080843
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr9_-_15510209 0.260 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr2_+_178077421 0.259 NM_194247
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3
chr18_+_55019720 0.259 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr10_-_61666236 0.258 NM_005436
CCDC6
coiled-coil domain containing 6
chr15_+_22833394 0.256 NM_001102610
NM_052903
TUBGCP5

tubulin, gamma complex associated protein 5

chr2_+_135676387 0.254 NM_001241
NM_058241
CCNT2

cyclin T2

chr2_-_128100673 0.253 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr17_+_46018888 0.249 NM_018129
PNPO
pyridoxamine 5'-phosphate oxidase
chr17_-_26941178 0.249 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr10_-_1095059 0.248 NM_004508
IDI1
isopentenyl-diphosphate delta isomerase 1
chr3_-_195270004 0.248 NM_006241
PPP1R2
protein phosphatase 1, regulatory (inhibitor) subunit 2
chrX_-_10851808 0.248 NM_033290
MID1
midline 1 (Opitz/BBB syndrome)
chr2_+_101436491 0.241 NM_002518
NPAS2
neuronal PAS domain protein 2
chr20_+_51588945 0.240 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr14_+_102228134 0.237 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr6_-_107780682 0.235 NM_020381
PDSS2
prenyl (decaprenyl) diphosphate synthase, subunit 2
chr11_-_63536112 0.227 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr12_-_31743822 0.226 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr15_-_35087748 0.220 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chrX_+_122993536 0.220 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr5_-_58571916 0.215 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr16_+_69599868 0.214 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr10_-_116286661 0.213 NM_006720
ABLIM1
actin binding LIM protein 1
chr18_-_28622624 0.211 NM_001941
NM_024423
DSC3

desmocollin 3

chr5_+_68800003 0.210 NM_001205255
OCLN
occludin
chr4_-_113437327 0.206 NM_024019
NEUROG2
neurogenin 2
chr5_-_64064483 0.204 NM_173829
SREK1IP1
SREK1-interacting protein 1
chr7_-_115670828 0.203 NM_001018058
NM_012252
TFEC

transcription factor EC

chr20_+_11898536 0.202 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr8_+_101162838 0.202 NM_005034
POLR2K
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
chr3_-_160283361 0.202 NM_002268
KPNA4
karyopherin alpha 4 (importin alpha 3)
chr17_-_47755340 0.201 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr4_+_76649826 0.200 NM_003715
USO1
USO1 vesicle docking protein homolog (yeast)
chr1_+_236687026 0.200 NM_201544
LGALS8
lectin, galactoside-binding, soluble, 8
chr2_-_214015053 0.200 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_+_10555948 0.196 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr6_-_94129059 0.194 NM_004440
EPHA7
EPH receptor A7
chr5_-_59783885 0.190 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_40566341 0.187 NM_001098414
NM_198484
ZNF621

zinc finger protein 621

chr15_+_40733302 0.186 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr3_-_121553907 0.180 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr1_-_220445831 0.176 NM_012414
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr22_+_24322248 0.175 NM_000854
GSTT2
GSTT2B
glutathione S-transferase theta 2
glutathione S-transferase theta 2B (gene/pseudogene)
chr1_-_160990971 0.175 NM_016946
F11R
F11 receptor
chr15_+_63481713 0.173 NM_016530
RAB8B
RAB8B, member RAS oncogene family
chr15_+_65914269 0.172 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr2_+_26987122 0.171 NM_017877
CENPA
C2orf18
centromere protein A
chromosome 2 open reading frame 18
chr5_-_59189620 0.169 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_+_10585978 0.166 NM_145655
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr17_+_59477169 0.162 NM_005994
TBX2
T-box 2
chr12_-_10022457 0.161 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr1_-_204329043 0.158 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr6_-_135271206 0.155 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr12_-_25055966 0.154 NM_001178093
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr3_+_126707380 0.147 NM_032242
PLXNA1
plexin A1
chr12_+_5019048 0.147 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr10_-_116444374 0.145 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr8_-_89339716 0.143 NM_005941
MMP16
matrix metallopeptidase 16 (membrane-inserted)
chr6_+_42788793 0.143 NM_015349
KIAA0240
KIAA0240
chr5_-_58882274 0.139 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_57261729 0.135 NM_012096
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr16_-_18937722 0.130 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr7_-_113559048 0.126 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr12_-_25055228 0.115 NM_001178094
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr4_-_66535652 0.107 NM_004439
NM_182472
EPHA5

EPH receptor A5

chr12_-_25102281 0.106 NM_001178091
NM_001178092
NM_005504
BCAT1


branched chain amino-acid transaminase 1, cytosolic


chr20_-_32307889 0.106 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr4_-_52904424 0.104 NM_000232
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr4_+_81952118 0.101 NM_001201
BMP3
bone morphogenetic protein 3
chr10_+_46222647 0.099 NM_001169106
NM_001169107
NM_015262
FAM21C


family with sequence similarity 21, member C


chr5_-_58295758 0.095 NM_001197223
PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_+_42642105 0.091 NM_005385
NKTR
natural killer-tumor recognition sequence
chr11_+_68228182 0.091 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr6_-_32163299 0.090 NM_022107
GPSM3
G-protein signaling modulator 3
chr14_-_57735614 0.090 NM_006544
EXOC5
exocyst complex component 5
chr5_+_40680021 0.088 NM_000958
PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr18_-_61034350 0.088 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr15_+_85291802 0.085 NM_014630
ZNF592
zinc finger protein 592
chr16_-_19729417 0.085 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr11_+_96123120 0.082 NM_003772
JRKL
jerky homolog-like (mouse)
chr1_-_151882360 0.082 NM_053055
THEM4
thioesterase superfamily member 4
chr13_-_21476895 0.078 NM_022459
XPO4
exportin 4
chr1_+_181452685 0.078 NM_000721
NM_001205293
NM_001205294
CACNA1E


calcium channel, voltage-dependent, R type, alpha 1E subunit


chr6_+_10521564 0.076 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_-_59064437 0.076 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_24882565 0.074 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr15_-_77712436 0.066 NM_024776
PEAK1
NKF3 kinase family member
chr17_-_73975507 0.065 NM_001185039
NM_004035
NM_007292
ACOX1


acyl-CoA oxidase 1, palmitoyl


chr2_+_73441344 0.065 NM_006062
SMYD5
SMYD family member 5
chr3_+_45927995 0.065 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr10_+_225932 0.060 NM_001202467
NM_001202468
ZMYND11

zinc finger, MYND-type containing 11

chr9_+_125133228 0.056 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr12_-_51420097 0.055 NM_000617
NM_001174126
NM_001174127
NM_001174128
SLC11A2



solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2



chr3_+_101498285 0.055 NM_001134456
FAM55C
family with sequence similarity 55, member C
chr10_-_116418056 0.049 NM_002313
ABLIM1
actin binding LIM protein 1
chr6_-_82462374 0.047 NM_017633
FAM46A
family with sequence similarity 46, member A
chr3_+_101498028 0.046 NM_145037
FAM55C
family with sequence similarity 55, member C

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
13.55 8.28e-04 GO:0017053 transcriptional repressor complex

Nothing significant found in function category.