Motif ID: AAUCUCU

Z-value: 0.531


Mature miRNA associated with seed AAUCUCU:

NamemiRBase Accession
hsa-miR-216b MIMAT0004959



Activity profile for motif AAUCUCU.

activity profile for motif AAUCUCU


Sorted Z-values histogram for motif AAUCUCU

Sorted Z-values for motif AAUCUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUCUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_57752051 8.575 NM_001023563
NM_001145078
ZNF805

zinc finger protein 805

chr11_+_92085261 7.550 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr14_+_92790151 6.065 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 5.745 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_-_52831817 5.638 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr18_-_13726582 5.236 NM_001098801
NM_152352
FAM210A

family with sequence similarity 210, member A

chr4_+_187112635 4.972 NM_207352
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr14_+_92788924 4.967 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr5_+_79783799 4.693 NM_205548
FAM151B
family with sequence similarity 151, member B
chr11_-_102962903 4.425 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chr16_-_4292052 4.229 NM_001098814
SRL
sarcalumenin
chr6_+_7590405 3.938 NM_152551
SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr3_-_42917632 3.880 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr6_+_11538486 3.591 NM_001100829
TMEM170B
transmembrane protein 170B
chr4_+_76439653 3.295 NM_144721
THAP6
THAP domain containing 6
chr7_-_129845216 3.201 NM_032842
TMEM209
transmembrane protein 209
chr18_-_21017816 3.165 NM_032933
TMEM241
transmembrane protein 241
chr19_+_52901101 2.877 NM_032423
ZNF528
zinc finger protein 528
chr7_-_44924946 2.562 NM_033224
PURB
purine-rich element binding protein B
chr15_+_42867708 2.466 NM_020759
STARD9
StAR-related lipid transfer (START) domain containing 9
chr22_+_24891114 2.444 NM_016327
UPB1
ureidopropionase, beta
chr18_+_11851388 2.436 NM_020412
CHMP1B
charged multivesicular body protein 1B
chr3_-_113233952 2.414 NM_144718
SPICE1
spindle and centriole associated protein 1
chr7_-_91509979 2.265 NM_006980
MTERF
mitochondrial transcription termination factor
chr4_-_88141614 2.261 NM_020803
KLHL8
kelch-like 8 (Drosophila)
chr4_-_13629270 2.145 NM_148894
BOD1L
biorientation of chromosomes in cell division 1-like
chr1_-_220263150 2.097 NM_006085
BPNT1
3'(2'), 5'-bisphosphate nucleotidase 1
chr19_+_44645708 2.023 NM_001144824
NM_006630
ZNF234

zinc finger protein 234

chr1_+_60280462 1.993 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr20_+_54933982 1.865 NM_080821
FAM210B
family with sequence similarity 210, member B
chr9_+_4985243 1.817 NM_004972
JAK2
Janus kinase 2
chr10_-_104473957 1.785 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr6_+_42018250 1.768 NM_138572
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr19_+_54024176 1.672 NM_018555
ZNF331
zinc finger protein 331
chr4_+_40058507 1.658 NM_018177
N4BP2
NEDD4 binding protein 2
chr11_+_60739114 1.644 NM_006725
CD6
CD6 molecule
chr5_+_130506635 1.620 NM_181705
LYRM7
Lyrm7 homolog (mouse)
chr11_-_59383616 1.606 NM_002556
OSBP
oxysterol binding protein
chr17_+_40834571 1.571 NM_003632
CNTNAP1
contactin associated protein 1
chr12_+_72233486 1.549 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr19_+_54041332 1.539 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr3_+_14989076 1.538 NM_003298
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr1_-_154155698 1.525 NM_001043351
NM_001043352
NM_001043353
NM_153649
TPM3



tropomyosin 3



chr14_+_71108373 1.497 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr7_-_79082870 1.476 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_+_94890777 1.473 NM_198150
ARSK
arylsulfatase family, member K
chr12_-_50236868 1.472 NM_181708
BCDIN3D
BCDIN3 domain containing
chr2_+_176957448 1.453 NM_000523
HOXD13
homeobox D13
chr19_-_36980336 1.434 NM_032838
NM_001145343
NM_001145344
NM_001145345
ZNF566



zinc finger protein 566



chr2_+_113875469 1.432 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr7_+_21467572 1.428 NM_003112
SP4
Sp4 transcription factor
chr1_-_151882360 1.419 NM_053055
THEM4
thioesterase superfamily member 4
chr7_+_43966007 1.404 NM_015983
UBE2D4
ubiquitin-conjugating enzyme E2D 4 (putative)
chr2_+_113885137 1.400 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr2_+_175260455 1.395 NM_001193528
NM_024583
SCRN3

secernin 3

chr1_-_114354906 1.389 NM_018364
RSBN1
round spermatid basic protein 1
chr15_-_45815001 1.388 NM_013309
SLC30A4
solute carrier family 30 (zinc transporter), member 4
chr11_-_18655962 1.382 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr7_-_92157748 1.381 NM_000466
PEX1
peroxisomal biogenesis factor 1
chr9_-_136857285 1.364 NM_001134398
NM_003371
VAV2

vav 2 guanine nucleotide exchange factor

chr7_+_35840595 1.358 NM_001011553
NM_001242956
NM_001788
SEPT7


septin 7


chr14_-_61748510 1.327 NM_001017970
TMEM30B
transmembrane protein 30B
chr14_-_80677839 1.323 NM_001007023
NM_001242502
NM_001242503
NM_013989
DIO2



deiodinase, iodothyronine, type II



chr12_+_133757994 1.316 NM_001165883
NM_001165884
NM_001165885
NM_001165886
NM_001165887
NM_003415
NM_152943
NM_001165881
NM_001165882
ZNF268








zinc finger protein 268








chr6_+_28317687 1.291 NM_001242894
NM_001242895
NM_024493
ZKSCAN3


zinc finger with KRAB and SCAN domains 3


chr11_-_133402227 1.283 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr9_+_17134974 1.271 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr7_+_138916230 1.268 NM_173569
UBN2
ubinuclein 2
chr16_+_29674282 1.267 NM_001030288
SPN
sialophorin
chr15_-_75743776 1.220 NM_015477
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr2_-_176866925 1.205 NM_030650
KIAA1715
KIAA1715
chr12_+_5019048 1.203 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr7_+_108210188 1.184 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr11_-_132812870 1.183 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr3_-_88108047 1.159 NM_001008390
NM_003663
CGGBP1

CGG triplet repeat binding protein 1

chr3_+_15469052 1.158 NM_033083
EAF1
ELL associated factor 1
chr16_-_57520326 1.153 NM_018110
DOK4
docking protein 4
chr16_-_10276610 1.152 NM_000833
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr20_+_32951054 1.144 NM_031483
ITCH
itchy E3 ubiquitin protein ligase homolog (mouse)
chr13_-_21476895 1.139 NM_022459
XPO4
exportin 4
chr9_-_124132503 1.138 NM_004099
NM_198194
STOM

stomatin

chr4_-_90759446 1.130 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_+_94536926 1.129 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory subunit 9A

chr15_-_75748123 1.128 NM_001145357
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr5_-_160975124 1.119 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr3_-_48700317 1.118 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr16_+_19125243 1.099 NM_001034841
ITPRIPL2
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr16_+_29674568 1.098 NM_003123
SPN
sialophorin
chr17_+_53342320 1.096 NM_002126
HLF
hepatic leukemia factor
chr12_+_69864065 1.089 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr8_-_133493003 1.083 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr4_+_54243810 1.083 NM_001134937
NM_001134938
NM_030917
FIP1L1


FIP1 like 1 (S. cerevisiae)


chr11_+_45868956 1.082 NM_021117
CRY2
cryptochrome 2 (photolyase-like)
chr4_+_81952118 1.072 NM_001201
BMP3
bone morphogenetic protein 3
chr15_-_75744029 1.071 NM_001145358
SIN3A
SIN3 transcription regulator homolog A (yeast)
chr19_-_36523540 1.052 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr16_+_8768403 1.040 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr17_-_16472463 1.023 NM_020653
ZNF287
zinc finger protein 287
chr9_+_87283453 1.019 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr16_-_10276115 0.997 NM_001134407
GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
chr4_+_96761238 0.985 NM_005390
PDHA2
pyruvate dehydrogenase (lipoamide) alpha 2
chr12_+_111051831 0.978 NM_001082537
NM_001082538
NM_001173976
NM_024549
NM_001173975
TCTN1




tectonic family member 1




chr8_-_22550708 0.970 NM_004430
EGR3
early growth response 3
chr7_-_115670828 0.967 NM_001018058
NM_012252
TFEC

transcription factor EC

chr3_+_39093480 0.957 NM_020839
WDR48
WD repeat domain 48
chr8_+_25042254 0.956 NM_024940
DOCK5
dedicator of cytokinesis 5
chr19_+_54058493 0.953 NM_001079907
ZNF331
zinc finger protein 331
chr2_+_192542860 0.948 NM_001031716
OBFC2A
oligonucleotide/oligosaccharide-binding fold containing 2A
chr1_-_146644045 0.939 NM_005399
PRKAB2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr14_-_57735614 0.933 NM_006544
EXOC5
exocyst complex component 5
chr21_-_19191643 0.926 NM_001100420
NM_001100421
NM_017447
C21orf91


chromosome 21 open reading frame 91


chr11_+_45868668 0.922 NM_001127457
CRY2
cryptochrome 2 (photolyase-like)
chr20_-_45280059 0.920 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr6_+_160769365 0.918 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr2_-_242255114 0.896 NM_005336
HDLBP
high density lipoprotein binding protein
chr4_-_90758126 0.884 NM_001146054
NM_007308
NM_000345
SNCA


synuclein, alpha (non A4 component of amyloid precursor)


chr7_-_99756275 0.879 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr3_-_171528227 0.865 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific

chrX_-_7895764 0.860 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr19_-_37407079 0.859 NM_001037232
ZNF829
zinc finger protein 829
chr22_-_38966066 0.857 NM_007068
DMC1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr7_-_143059696 0.845 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr19_-_36523770 0.843 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr7_+_154862545 0.842 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr7_-_135194823 0.839 NM_001008225
NM_001190847
NM_001190848
NM_001190849
NM_001190850
NM_013316
CNOT4





CCR4-NOT transcription complex, subunit 4





chr12_-_3982394 0.829 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr16_-_67840464 0.818 NM_020850
RANBP10
RAN binding protein 10
chr10_+_124134093 0.817 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr4_+_44680408 0.816 NM_021927
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr1_-_114430168 0.810 NM_001010922
BCL2L15
BCL2-like 15
chr9_+_35161950 0.807 NM_006377
UNC13B
unc-13 homolog B (C. elegans)
chr4_-_113437327 0.804 NM_024019
NEUROG2
neurogenin 2
chr20_-_45313122 0.803 NM_001011554
NM_001193340
SLC13A3

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3

chr1_-_28415071 0.800 NM_001990
EYA3
eyes absent homolog 3 (Drosophila)
chr11_+_119076974 0.790 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr6_-_33048554 0.785 NM_001242524
NM_001242525
HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

chr10_+_38383218 0.777 NM_001007094
NM_001178101
NM_003421
ZNF37A


zinc finger protein 37A


chr7_-_143059144 0.771 NM_014690
FAM131B
family with sequence similarity 131, member B
chr11_+_96123120 0.766 NM_003772
JRKL
jerky homolog-like (mouse)
chr22_-_19109912 0.765 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chrX_-_7895424 0.764 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr7_-_113559048 0.762 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr19_-_52531517 0.761 NM_025040
ZNF614
zinc finger protein 614
chr12_+_133613877 0.761 NM_003428
NM_001127372
ZNF84

zinc finger protein 84

chr1_+_44584521 0.753 NM_173484
KLF17
Kruppel-like factor 17
chr7_-_138665853 0.751 NM_001164665
NM_020910
KIAA1549

KIAA1549

chr17_-_29641094 0.742 NM_006495
EVI2B
ecotropic viral integration site 2B
chr4_-_110650965 0.738 NM_030821
PLA2G12A
phospholipase A2, group XIIA
chr16_-_19729417 0.736 NM_001012991
C16orf88
chromosome 16 open reading frame 88
chr1_-_115632047 0.734 NM_005725
TSPAN2
tetraspanin 2
chr19_+_54466289 0.729 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr17_+_32597239 0.726 NM_006273
CCL7
chemokine (C-C motif) ligand 7
chr11_-_128894008 0.724 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr10_+_86088156 0.720 NM_018999
FAM190B
family with sequence similarity 190, member B
chr8_-_22550057 0.719 NM_001199881
EGR3
early growth response 3
chr10_+_92980322 0.707 NM_032373
PCGF5
polycomb group ring finger 5
chr1_-_109940497 0.698 NM_002959
SORT1
sortilin 1
chr17_-_63052884 0.696 NM_006572
GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr7_+_134671244 0.695 NM_178563
AGBL3
ATP/GTP binding protein-like 3
chr8_-_22549901 0.694 NM_001199880
EGR3
early growth response 3
chr3_-_14583587 0.693 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr9_+_34989637 0.690 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr11_-_129062092 0.685 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr5_-_93447237 0.681 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr10_+_72163860 0.679 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr1_+_53192021 0.677 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr9_-_37465384 0.673 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr12_-_10022457 0.673 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr3_-_116164363 0.669 NM_002338
LSAMP
limbic system-associated membrane protein
chr14_-_53620032 0.668 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr5_-_87564615 0.657 NM_153354
TMEM161B
transmembrane protein 161B
chr5_+_68788387 0.656 NM_001205254
OCLN
occludin
chr16_+_8806825 0.652 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr15_-_42840992 0.652 NM_153260
LRRC57
leucine rich repeat containing 57
chr1_+_162039469 0.651 NM_001164757
NM_014697
NOS1AP

nitric oxide synthase 1 (neuronal) adaptor protein

chr10_-_1779669 0.637 NM_018702
ADARB2
adenosine deaminase, RNA-specific, B2
chr3_-_52479042 0.631 NM_020163
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr1_+_160085519 0.631 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr8_+_17354562 0.597 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr10_-_97321094 0.595 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr19_+_16830786 0.594 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr22_+_29999544 0.587 NM_000268
NM_016418
NM_181825
NM_181828
NM_181829
NM_181830
NM_181831
NM_181832
NM_181833
NF2








neurofibromin 2 (merlin)








chr21_+_35736322 0.582 NM_172201
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr22_+_26565424 0.570 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr6_+_13574649 0.567 NM_001193267
NM_001242827
NM_031244
NM_012241
SIRT5



sirtuin 5



chr3_+_49507470 0.557 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr17_-_62340652 0.548 NM_018469
TEX2
testis expressed 2
chr4_+_39046198 0.543 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr15_-_71055745 0.533 NM_018003
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr9_-_84303595 0.530 NM_005077
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr8_+_28351694 0.527 NM_017412
NM_145866
FZD3

frizzled family receptor 3

chr4_+_153700932 0.518 NM_001025593
NM_001025595
NM_014447
ARFIP1


ADP-ribosylation factor interacting protein 1


chr1_-_236030219 0.514 NM_000081
LYST
lysosomal trafficking regulator
chr10_+_17794250 0.509 NM_001098844
TMEM236
transmembrane protein 236
chr8_+_1922030 0.508 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr3_+_51428698 0.508 NM_013286
RBM15B
RNA binding motif protein 15B
chr7_+_155250705 0.505 NM_001427
EN2
engrailed homeobox 2
chr2_+_128848752 0.501 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr6_-_70992754 0.498 NM_078485
COL9A1
collagen, type IX, alpha 1
chr1_-_23521221 0.498 NM_000864
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 1.73e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.13 4.09e-02 GO:0043197 dendritic spine

Nothing significant found in function category.