Motif ID: AAUGCCC

Z-value: 0.648


Mature miRNA associated with seed AAUGCCC:

NamemiRBase Accession
hsa-miR-365 MIMAT0000710



Activity profile for motif AAUGCCC.

activity profile for motif AAUGCCC


Sorted Z-values histogram for motif AAUGCCC

Sorted Z-values for motif AAUGCCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAUGCCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_158731622 8.868 NM_001105
ACVR1
activin A receptor, type I
chr2_-_158732341 7.677 NM_001111067
ACVR1
activin A receptor, type I
chr6_-_134498973 7.645 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr6_-_134639195 7.357 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr11_+_69455837 7.308 NM_053056
CCND1
cyclin D1
chr3_-_123339423 7.128 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr6_-_134496006 6.417 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr9_-_14398981 6.266 NM_001190738
NFIB
nuclear factor I/B
chr3_-_123603144 5.782 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr9_-_14314036 5.672 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr6_-_134497069 5.636 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr3_+_171757413 5.502 NM_022763
FNDC3B
fibronectin type III domain containing 3B
chr2_-_153573858 5.483 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr12_-_15942350 5.137 NM_004447
EPS8
epidermal growth factor receptor pathway substrate 8
chr11_-_27742224 5.043 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr11_-_27741192 4.763 NM_001143807
BDNF
brain-derived neurotrophic factor
chr11_-_27721179 4.759 NM_170734
BDNF
brain-derived neurotrophic factor
chr11_-_27743604 4.686 NM_170731
BDNF
brain-derived neurotrophic factor
chr11_+_35160385 4.653 NM_000610
NM_001001389
NM_001001390
NM_001001391
NM_001001392
NM_001202555
NM_001202556
NM_001202557
CD44







CD44 molecule (Indian blood group)







chr11_-_27681195 4.324 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 95 entries
enrichment   p-value GO term description
11.16 3.62e-03 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
9.44 2.55e-03 GO:0030336 negative regulation of cell migration
9.44 2.55e-03 GO:2000146 negative regulation of cell motility
9.08 8.02e-04 GO:0040013 negative regulation of locomotion
8.82 2.50e-04 GO:0061138 morphogenesis of a branching epithelium
8.76 4.52e-03 GO:0051271 negative regulation of cellular component movement
7.45 1.22e-03 GO:0001763 morphogenesis of a branching structure
5.94 1.36e-04 GO:0002009 morphogenesis of an epithelium
5.84 3.10e-02 GO:0001655 urogenital system development
5.56 1.13e-04 GO:0045596 negative regulation of cell differentiation
5.52 6.65e-03 GO:0048732 gland development
5.26 6.14e-04 GO:0030334 regulation of cell migration
5.23 9.78e-05 GO:0048729 tissue morphogenesis
5.22 2.91e-02 GO:0035239 tube morphogenesis
5.19 7.12e-04 GO:2000145 regulation of cell motility
4.91 8.26e-03 GO:0003002 regionalization
4.89 1.01e-04 GO:0007389 pattern specification process
4.85 2.77e-04 GO:0051093 negative regulation of developmental process
4.75 2.07e-03 GO:0040012 regulation of locomotion
4.73 2.17e-03 GO:0051270 regulation of cellular component movement

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
2.37 6.56e-04 GO:0005654 nucleoplasm
2.04 2.50e-03 GO:0031981 nuclear lumen
1.96 1.69e-03 GO:0044428 nuclear part
1.75 4.26e-02 GO:0070013 intracellular organelle lumen
1.57 8.88e-05 GO:0005634 nucleus
1.35 2.66e-04 GO:0043231 intracellular membrane-bounded organelle
1.35 2.86e-04 GO:0043227 membrane-bounded organelle
1.30 9.66e-04 GO:0043229 intracellular organelle
1.29 1.09e-03 GO:0043226 organelle
1.25 2.40e-04 GO:0044424 intracellular part
1.22 1.97e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
8.91 4.72e-02 GO:0003707 steroid hormone receptor activity
6.35 2.91e-05 GO:0003682 chromatin binding
4.50 1.64e-02 GO:0000975 regulatory region DNA binding
4.50 1.64e-02 GO:0001067 regulatory region nucleic acid binding
4.50 1.64e-02 GO:0044212 transcription regulatory region DNA binding
4.43 3.34e-04 GO:0016563 transcription activator activity
3.64 2.51e-02 GO:0016564 transcription repressor activity
3.39 3.45e-05 GO:0043565 sequence-specific DNA binding
2.74 2.35e-04 GO:0001071 nucleic acid binding transcription factor activity
2.74 2.35e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.68 3.79e-04 GO:0030528 transcription regulator activity
1.50 6.58e-06 GO:0005515 protein binding
1.24 7.06e-05 GO:0005488 binding