Motif ID: ACAGUAU

Z-value: 1.121


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
hsa-miR-144 MIMAT0000436



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_195808958 34.292 NM_003234
 TFRC
transferrin receptor (p90, CD71)
chr3_-_195808997 33.766 NM_001128148
 TFRC
transferrin receptor (p90, CD71)
chr17_-_38574042 24.541 NM_001067
 TOP2A
topoisomerase (DNA) II alpha 170kDa
chr12_-_31479120 23.252 NM_001135811
NM_021238
NM_001135812
 FAM60A


family with sequence similarity 60, member A


chr20_-_32899607 17.845 NM_001161766
 AHCY
adenosylhomocysteinase
chr11_+_16760147 17.167 NM_014267
 C11orf58
chromosome 11 open reading frame 58
chr20_-_32891075 16.666 NM_000687
 AHCY
adenosylhomocysteinase
chr3_+_151985828 16.413 NM_021038
NM_207292
 MBNL1

muscleblind-like (Drosophila)

chr1_-_225616556 16.404 NM_194442
 LBR
lamin B receptor
chr1_-_95392501 16.018 NM_001839
 CNN3
calponin 3, acidic
chr4_-_139163222 15.884 NM_014331
 SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr3_+_150321065 15.812 NM_016275
 SELT
selenoprotein T
chr9_+_112542496 15.179 NM_053016
NM_007203
NM_147150
 PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr2_-_227663454 14.717 NM_005544
 IRS1
insulin receptor substrate 1
chr3_+_152017193 14.318 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
 MBNL1




muscleblind-like (Drosophila)




chr18_+_3453771 14.234 NM_173211
 TGIF1
TGFB-induced factor homeobox 1
chr1_+_167298280 14.135 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr18_+_3449972 14.069 NM_173209
NM_173208
NM_003244
 TGIF1


TGFB-induced factor homeobox 1


chr1_-_225615787 13.948 NM_002296
 LBR
lamin B receptor
chr18_+_3447607 13.873 NM_173207
 TGIF1
TGFB-induced factor homeobox 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 64 entries
enrichment   p-value GO term description
4.15 5.37e-03 GO:0030900 forebrain development
3.21 3.86e-02 GO:0030334 regulation of cell migration
3.17 2.60e-02 GO:0010608 posttranscriptional regulation of gene expression
3.17 4.52e-02 GO:2000145 regulation of cell motility
2.89 8.90e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.86 1.62e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.76 1.45e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.65 2.54e-04 GO:0051254 positive regulation of RNA metabolic process
2.64 5.03e-03 GO:0045892 negative regulation of transcription, DNA-dependent
2.63 3.22e-04 GO:0010628 positive regulation of gene expression
2.58 7.41e-03 GO:0051253 negative regulation of RNA metabolic process
2.52 4.14e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.51 4.14e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.49 8.08e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.44 2.15e-04 GO:0009891 positive regulation of biosynthetic process
2.43 1.62e-02 GO:0010629 negative regulation of gene expression
2.42 3.76e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.40 1.32e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.40 1.75e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.40 1.03e-02 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
4.52 4.44e-02 GO:0016585 chromatin remodeling complex
1.97 4.39e-04 GO:0005654 nucleoplasm
1.74 2.78e-04 GO:0044428 nuclear part
1.72 2.95e-03 GO:0031981 nuclear lumen
1.62 4.56e-03 GO:0043233 organelle lumen
1.61 4.40e-03 GO:0031974 membrane-enclosed lumen
1.58 1.38e-02 GO:0070013 intracellular organelle lumen
1.46 2.61e-06 GO:0005634 nucleus
1.32 1.02e-02 GO:0044446 intracellular organelle part
1.31 1.44e-02 GO:0044422 organelle part
1.24 1.69e-03 GO:0043231 intracellular membrane-bounded organelle
1.24 1.86e-03 GO:0043227 membrane-bounded organelle
1.21 6.48e-06 GO:0044424 intracellular part
1.20 1.64e-05 GO:0005622 intracellular
1.19 1.12e-02 GO:0043229 intracellular organelle
1.19 1.30e-02 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
4.41 1.24e-03 GO:0003714 transcription corepressor activity
3.26 4.33e-04 GO:0016563 transcription activator activity
2.74 3.89e-02 GO:0016564 transcription repressor activity
2.64 1.90e-02 GO:0003712 transcription cofactor activity
2.63 1.98e-02 GO:0000988 protein binding transcription factor activity
2.63 1.98e-02 GO:0000989 transcription factor binding transcription factor activity
2.35 1.88e-03 GO:0043565 sequence-specific DNA binding
2.26 6.79e-05 GO:0001071 nucleic acid binding transcription factor activity
2.26 6.79e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.26 2.21e-03 GO:0019899 enzyme binding
2.16 3.36e-04 GO:0030528 transcription regulator activity
1.76 3.05e-08 GO:0003676 nucleic acid binding
1.76 4.13e-05 GO:0003677 DNA binding
1.73 1.87e-02 GO:0005524 ATP binding
1.70 2.80e-02 GO:0032559 adenyl ribonucleotide binding
1.69 4.65e-04 GO:0000166 nucleotide binding
1.69 3.23e-02 GO:0030554 adenyl nucleotide binding
1.65 1.82e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.62 2.94e-02 GO:0032553 ribonucleotide binding
1.62 2.94e-02 GO:0032555 purine ribonucleotide binding