Motif ID: ACAUUCA

Z-value: 1.290


Mature miRNA associated with seed ACAUUCA:

NamemiRBase Accession
hsa-miR-181a MIMAT0000256
hsa-miR-181b MIMAT0000257
hsa-miR-181c MIMAT0000258
hsa-miR-181d MIMAT0002821
hsa-miR-4262 MIMAT0016894



Activity profile for motif ACAUUCA.

activity profile for motif ACAUUCA


Sorted Z-values histogram for motif ACAUUCA

Sorted Z-values for motif ACAUUCA



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAUUCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_44650260 18.448 NM_001134771
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr4_+_158141735 18.071 NM_000826
NM_001083619
NM_001083620
 GRIA2


glutamate receptor, ionotropic, AMPA 2


chr20_+_44657812 17.641 NM_020708
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr22_-_39548448 17.532 NM_175709
 CBX7
chromobox homolog 7
chr20_-_4795768 14.221 NM_170774
 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr20_-_4804067 13.939 NM_014737
 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr3_-_57113292 13.304 NM_001128615
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr8_-_103136486 13.162 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
 NCALD





neurocalcin delta





chr10_+_129845806 12.932 NM_130435
 PTPRE
protein tyrosine phosphatase, receptor type, E
chr7_+_153584383 12.931 NM_001039350
 DPP6
dipeptidyl-peptidase 6
chr15_+_80696569 12.879 NM_014862
 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_+_129705299 12.752 NM_006504
 PTPRE
protein tyrosine phosphatase, receptor type, E
chr8_-_103137134 12.750 NM_001040630
 NCALD
neurocalcin delta
chr14_+_90863302 12.512 NM_006888
 CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr22_-_39240016 12.388 NM_014293
 NPTXR
neuronal pentraxin receptor
chr1_+_50513685 12.261 NM_001144777
 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_-_108745569 12.238 NM_014819
 PJA2
praja ring finger 2
chr14_+_75745480 11.949 NM_005252
 FOS
FBJ murine osteosarcoma viral oncogene homolog
chr16_+_11762235 11.827 NM_003498
 SNN
stannin
chr9_-_4726226 11.739 NM_001199856
 AK3
adenylate kinase 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
2.89 1.60e-02 GO:0000165 MAPKKK cascade
2.89 4.07e-02 GO:0048011 nerve growth factor receptor signaling pathway
2.74 2.95e-03 GO:0043434 response to peptide hormone stimulus
2.70 7.79e-09 GO:0006468 protein phosphorylation
2.55 2.47e-02 GO:0070647 protein modification by small protein conjugation or removal
2.50 5.34e-08 GO:0016310 phosphorylation
2.45 2.25e-09 GO:0006793 phosphorus metabolic process
2.45 2.25e-09 GO:0006796 phosphate metabolic process
2.37 1.67e-02 GO:0007268 synaptic transmission
2.25 2.61e-02 GO:0019226 transmission of nerve impulse
2.25 2.61e-02 GO:0035637 multicellular organismal signaling
2.18 3.76e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.15 1.23e-02 GO:0009725 response to hormone stimulus
2.07 3.14e-02 GO:0030030 cell projection organization
2.06 2.02e-02 GO:0009719 response to endogenous stimulus
2.04 5.31e-10 GO:0006464 protein modification process
2.00 4.31e-02 GO:0019220 regulation of phosphate metabolic process
2.00 4.31e-02 GO:0051174 regulation of phosphorus metabolic process
1.97 2.98e-09 GO:0043412 macromolecule modification
1.93 1.65e-02 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.29 1.48e-03 GO:0005634 nucleus
1.17 4.49e-06 GO:0005622 intracellular
1.15 2.31e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
5.67 2.62e-02 GO:0042826 histone deacetylase binding
5.42 3.68e-02 GO:0046332 SMAD binding
2.91 6.38e-07 GO:0004674 protein serine/threonine kinase activity
2.57 1.01e-02 GO:0005083 small GTPase regulator activity
2.36 3.76e-05 GO:0004672 protein kinase activity
2.30 9.35e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.24 1.13e-02 GO:0019904 protein domain specific binding
2.22 1.53e-05 GO:0016301 kinase activity
2.10 2.69e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.90 1.60e-02 GO:0019899 enzyme binding
1.74 2.64e-02 GO:0001071 nucleic acid binding transcription factor activity
1.74 2.64e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.69 1.81e-05 GO:0008270 zinc ion binding
1.62 7.10e-03 GO:0032559 adenyl ribonucleotide binding
1.62 7.50e-03 GO:0005524 ATP binding
1.61 8.58e-03 GO:0030554 adenyl nucleotide binding
1.57 3.20e-04 GO:0046914 transition metal ion binding
1.46 9.39e-06 GO:0046872 metal ion binding
1.45 2.14e-05 GO:0043169 cation binding
1.44 2.55e-05 GO:0043167 ion binding