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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 1.217

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_5136556	37.019	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5136589	33.584		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5136613	33.233		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr2_-_10942642	30.126		PDIA6	protein disulfide isomerase family A, member 6
chr5_+_115898218	21.633
chr12_-_102512277	20.577	NM_024057	NUP37	nucleoporin 37kDa
chr8_-_86290333	17.994	NM_001128829 NM_001128830 NM_001128831 NM_001738	CA1	carbonic anhydrase I
chr14_-_55650348	17.271		DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr3_-_141747434	16.114	NM_001178141 NM_001178142 NM_006286	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr13_+_53035227	14.944		CKAP2	cytoskeleton associated protein 2
chr19_+_13134782	14.356		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr18_+_33234532	14.009	NM_020474	GALNT1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr10_+_5005685	13.699		AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr1_+_167298280	13.582	NM_001198783	POU2F1	POU class 2 homeobox 1
chr4_-_72649734	13.171	NM_000583	GC	group-specific component (vitamin D binding protein)
chr11_-_118900078	11.907	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr4_+_146031528	11.854		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr6_+_21593963	11.688	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr20_-_34243118	11.633		RBM12	RNA binding motif protein 12
chr9_-_14086901	11.325		NFIB	nuclear factor I/B
chr12_+_20963637	10.639	NM_019844	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr15_-_56209305	10.452	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr6_+_64356430	10.390	NM_015153	PHF3	PHD finger protein 3
chr10_+_5005601	10.341		AKR1C1 AKR1C3	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chrX_+_118714297	10.209	NM_181777	UBE2A	ubiquitin-conjugating enzyme E2A
chr3_-_57234279	9.627	NM_003865	HESX1	HESX homeobox 1
chr7_-_25268057	9.485	NM_022150	NPVF	neuropeptide VF precursor
chr10_-_5045967	9.466	NM_001135241	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr16_+_56817367	9.251	NM_001242796	NUP93	nucleoporin 93kDa
chr2_+_204055404	9.046		RPL12	ribosomal protein L12
chr7_-_26232148	8.449		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr11_+_114167197	8.402		NNMT	nicotinamide N-methyltransferase
chr12_+_50869531	8.208		LARP4	La ribonucleoprotein domain family, member 4
chr11_+_114167168	8.077		NNMT	nicotinamide N-methyltransferase
chr6_+_34206567	7.988	NM_145905	HMGA1	high mobility group AT-hook 1
chr10_+_89267589	7.969	NM_001178118	MINPP1	multiple inositol-polyphosphate phosphatase 1
chr11_+_114166534	7.633	NM_006169	NNMT	nicotinamide N-methyltransferase
chr1_+_68150858	7.502	NM_001199741 NM_001199742 NM_001924	GADD45A	growth arrest and DNA-damage-inducible, alpha
chr3_-_113897849	7.418	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr12_+_54410893	7.396		HOXC5 HOXC6	homeobox C5 homeobox C6
chr4_+_140587086	7.314		MGST2	microsomal glutathione S-transferase 2
chr1_+_74701070	7.289	NM_015978	TNNI3K	TNNI3 interacting kinase
chr10_-_75006963	7.279	NM_015190	DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr6_-_86351156	7.241	NM_001159675 NM_001159676	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_5005453	7.220	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr11_+_101983170	7.220	NM_001195045	YAP1	Yes-associated protein 1
chr6_+_34204928	7.108		HMGA1	high mobility group AT-hook 1
chr1_+_167298382	7.023		POU2F1	POU class 2 homeobox 1
chr4_+_74269971	6.928	NM_000477	ALB	albumin
chr8_-_86253863	6.924	NM_001164830	CA1	carbonic anhydrase I
chr5_-_98262217	6.894	NM_001270	CHD1	chromodomain helicase DNA binding protein 1
chr5_+_102465256	6.831	NM_015216	PPIP5K2	diphosphoinositol pentakisphosphate kinase 2
chrX_+_99839789	6.817	NM_022144	TNMD	tenomodulin
chr9_+_97521930	6.735	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr1_+_236557643	6.662	NM_145861	EDARADD	EDAR-associated death domain
chr4_-_7069801	6.580		GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chrX_+_70765479	6.518		OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr14_+_102276279	6.480		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chrX_+_123234462	6.459		STAG2	stromal antigen 2
chr6_+_64286348	6.368		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr2_-_100046262	6.347		REV1	REV1 homolog (S. cerevisiae)
chr1_+_64088886	6.342	NM_001172818	PGM1	phosphoglucomutase 1
chr17_-_64225496	6.235	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr22_-_36236421	6.187	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr8_-_72268720	6.043	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr4_-_70518964	5.934	NM_001252274 NM_001252275 NM_006798	UGT2A1	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr2_+_234580504	5.905	NM_021027	UGT1A9	UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_+_49467670	5.883	NM_001010904	GLYATL3	glycine-N-acyltransferase-like 3
chr17_-_46622274	5.818	NM_002145	HOXB2	homeobox B2
chr8_+_9953061	5.715	NM_001135671 NM_001199729	MSRA	methionine sulfoxide reductase A
chr17_-_15554809	5.625		TRIM16	tripartite motif containing 16
chr14_-_69354900	5.599		ACTN1	actinin, alpha 1
chr2_+_234637772	5.591	NM_019093	UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3
chr2_-_190927321	5.566	NM_005259	MSTN	myostatin
chr13_+_53216564	5.514		HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2
chr6_-_138820580	5.475
chr9_-_104198045	5.447	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr9_-_86584079	5.442		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr7_+_115863004	5.362	NM_152829	TES	testis derived transcript (3 LIM domains)
chr19_-_40331153	5.285		FBL	fibrillarin
chr3_-_25683825	5.229		TOP2B	topoisomerase (DNA) II beta 180kDa
chr2_+_171784947	5.209	NM_001201428 NM_015530	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr7_-_27205148	5.196	NM_152739	HOXA9	homeobox A9
chr6_+_136172802	5.175	NM_018945	PDE7B	phosphodiesterase 7B
chr14_+_58711457	5.159	NM_002788 NM_152132	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr11_-_27742224	5.098	NM_001143805 NM_001143806 NM_170732	BDNF	brain-derived neurotrophic factor
chr14_+_58711599	5.088		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr3_+_63884074	5.069	NM_001177387	ATXN7	ataxin 7
chr7_-_72936538	4.990		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr5_+_138211084	4.863		CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr20_+_30326903	4.857	NM_012112	TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)
chr2_+_172821874	4.857		HAT1	histone acetyltransferase 1
chr14_+_58711555	4.854		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr11_+_87032428	4.797		TMEM135	transmembrane protein 135
chr2_-_74382352	4.778
chr2_-_136634002	4.765	NM_005915	MCM6	minichromosome maintenance complex component 6
chr15_+_57511616	4.711	NM_207040	TCF12	transcription factor 12
chr3_+_136649316	4.690	NM_001190796	NCK1	NCK adaptor protein 1
chr14_+_67831484	4.654		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_109204745	4.651	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_-_158656487	4.625	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr8_-_82395401	4.613	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr14_+_74035762	4.559	NM_006821	ACOT2	acyl-CoA thioesterase 2
chr13_-_103719195	4.535	NM_000452	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr7_-_27205123	4.527		HOXA9	homeobox A9
chr4_+_1902352	4.519	NM_133334	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr4_-_74088773	4.465		ANKRD17	ankyrin repeat domain 17
chr17_-_38821286	4.457	NM_152349	KRT222	keratin 222
chr2_-_133429069	4.438	NM_001077427	LYPD1	LY6/PLAUR domain containing 1
chr5_+_65372744	4.429		ERBB2IP	erbb2 interacting protein
chr5_+_44808967	4.428	NM_016640	MRPS30	mitochondrial ribosomal protein S30
chr15_+_49715374	4.390	NM_002009	FGF7	fibroblast growth factor 7
chr3_+_151985828	4.365	NM_021038 NM_207292	MBNL1	muscleblind-like (Drosophila)
chr8_+_66582107	4.349	NM_001145838	MTFR1	mitochondrial fission regulator 1
chr12_-_54653369	4.340	NM_001127321	CBX5	chromobox homolog 5
chr17_-_39191100	4.327	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr12_-_102874340	4.289		IGF1	insulin-like growth factor 1 (somatomedin C)
chr5_+_162930230	4.284	NM_182796	MAT2B	methionine adenosyltransferase II, beta
chr10_+_75673346	4.277		PLAU	plasminogen activator, urokinase
chr11_+_113775517	4.276	NM_006028	HTR3B	5-hydroxytryptamine (serotonin) receptor 3B
chr2_+_228356287	4.262		AGFG1	ArfGAP with FG repeats 1
chr21_-_33074101	4.241		SCAF4	SR-related CTD-associated factor 4
chr12_-_14132920	4.238	NM_000834	GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr17_-_49124128	4.234	NM_001251971	SPAG9	sperm associated antigen 9
chr2_-_61764661	4.194		XPO1	exportin 1 (CRM1 homolog, yeast)
chr2_+_109204904	4.139	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chr11_+_99426872	4.114	NM_175566	CNTN5	contactin 5
chr5_+_6746100	4.086	NM_001171806	PAPD7	PAP associated domain containing 7
chr15_+_94899163	4.073	NM_001159644	MCTP2	multiple C2 domains, transmembrane 2
chr12_+_16064105	4.037	NM_015954	DERA	deoxyribose-phosphate aldolase (putative)
chr5_-_111091947	4.032	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr5_-_179044835	4.023		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr6_-_36515245	4.001	NM_007271	STK38	serine/threonine kinase 38
chr20_+_32150139	3.987	NM_001039709 NM_005093	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr12_-_91398757	3.981	NM_004950	EPYC	epiphycan
chr3_-_196911001	3.965	NM_001204387 NM_001204388	DLG1	discs, large homolog 1 (Drosophila)
chr9_+_135854097	3.964	NM_001135031 NM_004188	GFI1B	growth factor independent 1B transcription repressor
chr5_-_140895407	3.962		DIAPH1	diaphanous homolog 1 (Drosophila)
chr6_+_167525294	3.948	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr15_+_52201590	3.946		TMOD3	tropomodulin 3 (ubiquitous)
chr18_-_51690988	3.924		MBD2	methyl-CpG binding domain protein 2
chr3_+_149192367	3.921	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr21_-_36421586	3.918	NM_001754	RUNX1	runt-related transcription factor 1
chr2_+_234545099	3.903	NM_019075	UGT1A10	UDP glucuronosyltransferase 1 family, polypeptide A10
chr16_+_56815703	3.896	NM_001242795	NUP93	nucleoporin 93kDa
chr2_+_216986817	3.877		XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chrX_-_55057408	3.851	NM_000032 NM_001037967 NM_001037968	ALAS2	aminolevulinate, delta-, synthase 2
chr4_-_7069755	3.840	NM_025196	GRPEL1	GrpE-like 1, mitochondrial (E. coli)
chr10_+_94352960	3.822		KIF11	kinesin family member 11
chr14_+_102276125	3.804	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chrX_-_18690187	3.755	NM_000330	RS1	retinoschisin 1
chr1_+_78470593	3.735	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_-_93257950	3.730	NM_005665	EVI5	ecotropic viral integration site 5
chr14_-_23504353	3.650	NM_001144932 NM_002797 NM_001130725	PSMB5	proteasome (prosome, macropain) subunit, beta type, 5
chr12_-_54653317	3.625	NM_001127322	CBX5	chromobox homolog 5
chr22_-_37098620	3.569	NM_006078	CACNG2	calcium channel, voltage-dependent, gamma subunit 2
chr10_-_98325100	3.545		TM9SF3	transmembrane 9 superfamily member 3
chr3_-_27498244	3.536	NM_003615	SLC4A7	solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr1_-_159684274	3.528	NM_000567	CRP	C-reactive protein, pentraxin-related
chr6_-_155777036	3.526	NM_015718	NOX3	NADPH oxidase 3
chr2_-_200329810	3.518	NM_001172517	SATB2	SATB homeobox 2
chr1_+_32661018	3.508		TXLNA	taxilin alpha
chr7_+_107110501	3.506	NM_005295	GPR22	G protein-coupled receptor 22
chr2_+_211458078	3.471	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr5_+_132432880	3.447		HSPA4	heat shock 70kDa protein 4
chr4_+_155484131	3.446	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr20_-_7921068	3.441	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr6_-_25874439	3.419	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr6_+_34204576	3.388	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr3_+_149192479	3.368		TM4SF4	transmembrane 4 L six family member 4
chr17_-_46682333	3.348	NM_018952	HOXB6	homeobox B6
chr4_-_111563278	3.343	NM_001204397 NM_001204398 NM_001204399 NM_153426 NM_153427	PITX2	paired-like homeodomain 2
chr17_-_79876024	3.337		SIRT7	sirtuin 7
chr3_-_194188967	3.335	NM_024524	ATP13A3	ATPase type 13A3
chr2_+_109223600	3.331	NM_001193482	LIMS1	LIM and senescent cell antigen-like domains 1
chr4_+_41614725	3.322		LIMCH1	LIM and calponin homology domains 1
chr1_+_168250277	3.318	NM_005149	TBX19	T-box 19
chr11_-_83393436	3.315	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chr13_+_98605928	3.283	NM_002271	IPO5	importin 5
chr2_+_86333304	3.265	NM_017952	PTCD3	Pentatricopeptide repeat domain 3
chr17_-_48785016	3.265	NM_052855	ANKRD40	ankyrin repeat domain 40
chr9_+_36572844	3.225	NM_014791	MELK	maternal embryonic leucine zipper kinase
chr8_-_6420454	3.201	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr7_+_28452143	3.199	NM_182898	CREB5	cAMP responsive element binding protein 5
chr14_-_65409445	3.190	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr4_+_54292035	3.187		FIP1L1	FIP1 like 1 (S. cerevisiae)
chr10_-_94257470	3.180	NM_001165946	IDE	insulin-degrading enzyme
chr5_-_95158465	3.173	NM_001118890 NM_001243658 NM_001243659 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr9_+_79968344	3.171		VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr22_-_36236264	3.162		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_155538096	3.148	NM_001010927	TIAM2	T-cell lymphoma invasion and metastasis 2
chr7_+_80275634	3.143	NM_001127443 NM_001127444	CD36	CD36 molecule (thrombospondin receptor)
chr15_+_66797632	3.132		ZWILCH	Zwilch, kinetochore associated, homolog (Drosophila)
chr6_-_75965845	3.127		TMEM30A	transmembrane protein 30A
chr2_-_192711923	3.125	NM_004657	SDPR	serum deprivation response
chr5_+_126859157	3.108		PRRC1	proline-rich coiled-coil 1
chr2_+_234627423	3.064	NM_007120	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr7_+_134212343	3.047	NM_020299	AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)
chr5_-_95158365	3.041		GLRX	glutaredoxin (thioltransferase)
chr17_+_28268622	3.018	NM_198529	EFCAB5	EF-hand calcium binding domain 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.87e-13	GO:0009987	cellular process
1.26	1.19e-10	GO:0065007	biological regulation
1.27	1.31e-09	GO:0050789	regulation of biological process
1.30	2.01e-09	GO:0044237	cellular metabolic process
1.66	1.21e-08	GO:0048513	organ development
1.96	2.29e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.42	2.55e-08	GO:0032502	developmental process
1.25	5.01e-08	GO:0008152	metabolic process
1.28	1.13e-07	GO:0050896	response to stimulus
1.45	1.22e-07	GO:0034641	cellular nitrogen compound metabolic process
1.55	1.98e-07	GO:0042221	response to chemical stimulus
1.44	2.06e-07	GO:0006807	nitrogen compound metabolic process
2.12	2.31e-07	GO:0010628	positive regulation of gene expression
1.53	3.44e-07	GO:0048519	negative regulation of biological process
2.16	4.16e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.27	4.34e-07	GO:0044238	primary metabolic process
2.04	4.36e-07	GO:0010557	positive regulation of macromolecule biosynthetic process
1.41	5.56e-07	GO:0007275	multicellular organismal development
1.24	1.10e-06	GO:0050794	regulation of cellular process
1.94	1.42e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.54	1.76e-06	GO:0048523	negative regulation of cellular process
1.39	1.77e-06	GO:0080090	regulation of primary metabolic process
1.41	2.18e-06	GO:0060255	regulation of macromolecule metabolic process
1.42	2.52e-06	GO:0048856	anatomical structure development
1.91	3.44e-06	GO:0009891	positive regulation of biosynthetic process
1.29	4.60e-06	GO:0032501	multicellular organismal process
1.44	7.15e-06	GO:0048731	system development
1.93	1.06e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
2.01	1.06e-05	GO:0051254	positive regulation of RNA metabolic process
1.35	1.17e-05	GO:0019222	regulation of metabolic process
1.44	1.37e-05	GO:0048518	positive regulation of biological process
1.32	1.45e-05	GO:0044260	cellular macromolecule metabolic process
1.69	1.75e-05	GO:0009893	positive regulation of metabolic process
1.49	2.10e-05	GO:0090304	nucleic acid metabolic process
1.43	2.20e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.91	2.62e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.55	2.67e-05	GO:0010467	gene expression
1.36	2.82e-05	GO:0031323	regulation of cellular metabolic process
1.49	3.03e-05	GO:0065008	regulation of biological quality
1.70	3.14e-05	GO:0031325	positive regulation of cellular metabolic process
1.29	3.52e-05	GO:0043170	macromolecule metabolic process
1.70	4.54e-05	GO:0010604	positive regulation of macromolecule metabolic process
1.45	4.61e-05	GO:0048522	positive regulation of cellular process
2.15	7.92e-05	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.45	1.51e-04	GO:0051252	regulation of RNA metabolic process
1.42	1.71e-04	GO:0010468	regulation of gene expression
1.43	1.81e-04	GO:0010556	regulation of macromolecule biosynthetic process
2.38	2.01e-04	GO:0001501	skeletal system development
1.40	2.31e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.78	2.35e-04	GO:0006351	transcription, DNA-dependent
1.89	2.38e-04	GO:0009790	embryo development
1.53	2.55e-04	GO:0009059	macromolecule biosynthetic process
1.43	2.59e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.52	2.61e-04	GO:0016070	RNA metabolic process
1.94	4.31e-04	GO:0009887	organ morphogenesis
2.13	4.45e-04	GO:0032583	regulation of gene-specific transcription
1.45	4.79e-04	GO:0006355	regulation of transcription, DNA-dependent
1.71	4.85e-04	GO:0032774	RNA biosynthetic process
1.39	5.03e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52	6.04e-04	GO:0034645	cellular macromolecule biosynthetic process
1.39	7.80e-04	GO:0031326	regulation of cellular biosynthetic process
2.07	1.07e-03	GO:0051094	positive regulation of developmental process
1.38	1.17e-03	GO:0009889	regulation of biosynthetic process
1.32	1.21e-03	GO:0071840	cellular component organization or biogenesis
9.12	1.40e-03	GO:0060416	response to growth hormone stimulus
2.23	1.83e-03	GO:0045597	positive regulation of cell differentiation
1.68	2.47e-03	GO:0070887	cellular response to chemical stimulus
2.65	2.59e-03	GO:0048732	gland development
1.38	2.60e-03	GO:0009058	biosynthetic process
1.32	2.73e-03	GO:0016043	cellular component organization
1.66	2.97e-03	GO:0009892	negative regulation of metabolic process
1.39	3.07e-03	GO:0006950	response to stress
2.14	3.26e-03	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.27	3.33e-03	GO:0051716	cellular response to stimulus
1.38	4.15e-03	GO:0044249	cellular biosynthetic process
1.50	5.35e-03	GO:0009653	anatomical structure morphogenesis
1.69	5.99e-03	GO:0009888	tissue development
4.91	7.87e-03	GO:0030193	regulation of blood coagulation
1.67	7.93e-03	GO:0042592	homeostatic process
1.65	9.90e-03	GO:0031324	negative regulation of cellular metabolic process
1.63	1.52e-02	GO:0050793	regulation of developmental process
3.44	1.75e-02	GO:0048706	embryonic skeletal system development
4.56	1.87e-02	GO:0045639	positive regulation of myeloid cell differentiation
4.56	1.87e-02	GO:0050818	regulation of coagulation
1.70	2.05e-02	GO:2000026	regulation of multicellular organismal development
1.72	2.12e-02	GO:0006082	organic acid metabolic process
2.76	2.30e-02	GO:0006805	xenobiotic metabolic process
2.76	2.30e-02	GO:0071466	cellular response to xenobiotic stimulus
2.38	2.34e-02	GO:0043193	positive regulation of gene-specific transcription
2.21	2.42e-02	GO:0007346	regulation of mitotic cell cycle
2.02	2.48e-02	GO:0043009	chordate embryonic development
2.74	2.61e-02	GO:0009410	response to xenobiotic stimulus
1.51	2.66e-02	GO:0051239	regulation of multicellular organismal process
1.61	2.72e-02	GO:0010605	negative regulation of macromolecule metabolic process
2.19	2.89e-02	GO:0048545	response to steroid hormone stimulus
3.31	2.97e-02	GO:0045637	regulation of myeloid cell differentiation
2.00	3.33e-02	GO:0009792	embryo development ending in birth or egg hatching
1.50	3.94e-02	GO:0010033	response to organic substance
2.06	4.98e-02	GO:0032787	monocarboxylic acid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.51	1.71e-07	GO:0043233	organelle lumen
1.49	6.87e-07	GO:0031974	membrane-enclosed lumen
1.49	2.36e-06	GO:0044428	nuclear part
1.54	2.43e-06	GO:0031981	nuclear lumen
1.75	3.43e-06	GO:0044421	extracellular region part
1.47	3.70e-06	GO:0070013	intracellular organelle lumen
1.86	4.30e-06	GO:0005615	extracellular space
1.59	6.64e-05	GO:0005654	nucleoplasm
1.10	4.92e-04	GO:0044424	intracellular part
1.21	6.53e-04	GO:0005634	nucleus
1.74	7.61e-04	GO:0044451	nucleoplasm part
1.12	1.74e-03	GO:0043226	organelle
1.12	2.36e-03	GO:0043229	intracellular organelle
1.14	2.69e-03	GO:0005737	cytoplasm
1.13	2.96e-03	GO:0043227	membrane-bounded organelle
1.13	3.36e-03	GO:0043231	intracellular membrane-bounded organelle
2.23	3.43e-03	GO:0005667	transcription factor complex
1.36	6.78e-03	GO:0005576	extracellular region
1.09	1.01e-02	GO:0005622	intracellular
1.25	1.31e-02	GO:0032991	macromolecular complex
1.26	3.89e-02	GO:0043234	protein complex
3.74	4.59e-02	GO:0031093	platelet alpha granule lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.30	5.80e-14	GO:0005515	protein binding
1.14	8.39e-10	GO:0005488	binding
2.01	7.30e-07	GO:0043565	sequence-specific DNA binding
1.75	9.67e-06	GO:0001071	nucleic acid binding transcription factor activity
1.75	9.67e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.66	2.23e-04	GO:0030528	transcription regulator activity
1.64	4.50e-04	GO:0005102	receptor binding
5.70	2.64e-03	GO:0015020	glucuronosyltransferase activity
1.28	6.38e-03	GO:0003676	nucleic acid binding
2.29	1.56e-02	GO:0000975	regulatory region DNA binding
2.29	1.56e-02	GO:0001067	regulatory region nucleic acid binding
2.29	1.56e-02	GO:0044212	transcription regulatory region DNA binding
2.30	1.94e-02	GO:0010843	promoter binding
1.62	1.97e-02	GO:0019899	enzyme binding
1.32	2.63e-02	GO:0003677	DNA binding
1.89	2.93e-02	GO:0003712	transcription cofactor activity
1.88	3.13e-02	GO:0000988	protein binding transcription factor activity
1.88	3.13e-02	GO:0000989	transcription factor binding transcription factor activity
2.01	3.23e-02	GO:0008134	transcription factor binding
1.56	4.78e-02	GO:0003723	RNA binding