Motif ID: AGCACCA

Z-value: 1.885


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a MIMAT0000086
hsa-miR-29b MIMAT0000100
hsa-miR-29c MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_94023872 45.283 NM_000089
 COL1A2
collagen, type I, alpha 2
chr2_+_189839078 41.032 NM_000090
 COL3A1
collagen, type III, alpha 1
chr13_-_110959441 27.733 NM_001845
 COL4A1
collagen, type IV, alpha 1
chr2_-_190044330 27.648 NM_000393
 COL5A2
collagen, type V, alpha 2
chr3_-_120169493 25.937 NM_007085
 FSTL1
follistatin-like 1
chr9_+_137533643 25.618 NM_000093
 COL5A1
collagen, type V, alpha 1
chr5_-_151066492 25.323 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr16_+_55515468 24.098 NM_001127891
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_238322840 23.937 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr15_-_48937795 22.419 NM_000138
 FBN1
fibrillin 1
chr2_-_1748285 22.152 NM_012293
 PXDN
peroxidasin homolog (Drosophila)
chr16_+_55512801 21.935 NM_004530
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr14_+_92790151 21.581 NM_153646
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr13_+_110959592 21.401 NM_001846
 COL4A2
collagen, type IV, alpha 2
chr14_+_92788924 21.314 NM_153648
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 21.097 NM_153647
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr11_+_75273100 18.911 NM_001207014
NM_001235
 SERPINH1

serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)

chr5_-_121412805 16.590 NM_001178102
 LOX
lysyl oxidase
chr1_-_204380903 15.883 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr17_-_48278987 15.603 NM_000088
 COL1A1
collagen, type I, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 66 entries
enrichment   p-value GO term description
32.17 1.70e-03 GO:0032964 collagen biosynthetic process
14.30 1.56e-08 GO:0030199 collagen fibril organization
10.72 4.00e-03 GO:0045646 regulation of erythrocyte differentiation
9.19 2.78e-03 GO:0043588 skin development
6.58 1.28e-02 GO:0060041 retina development in camera-type eye
6.16 1.09e-06 GO:0030198 extracellular matrix organization
4.25 2.13e-04 GO:0043062 extracellular structure organization
2.93 3.58e-02 GO:0030168 platelet activation
2.76 2.24e-02 GO:0001944 vasculature development
2.46 3.85e-03 GO:0072358 cardiovascular system development
2.46 3.85e-03 GO:0072359 circulatory system development
2.46 1.70e-02 GO:0016477 cell migration
2.44 9.66e-03 GO:0051094 positive regulation of developmental process
2.28 1.96e-04 GO:2000026 regulation of multicellular organismal development
2.24 3.80e-03 GO:0030030 cell projection organization
2.24 1.53e-02 GO:0006928 cellular component movement
2.23 1.01e-02 GO:0042060 wound healing
2.23 1.27e-02 GO:0048666 neuron development
2.20 5.74e-05 GO:0050793 regulation of developmental process
2.15 7.20e-03 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
32.17 8.07e-03 GO:0005588 collagen type V
23.40 3.48e-08 GO:0005583 fibrillar collagen
21.45 3.58e-03 GO:0005587 collagen type IV
18.38 8.14e-03 GO:0030935 sheet-forming collagen
16.98 2.55e-17 GO:0005581 collagen
12.87 4.53e-02 GO:0030934 anchoring collagen
8.04 4.97e-03 GO:0001725 stress fiber
7.69 2.18e-14 GO:0044420 extracellular matrix part
7.51 8.10e-03 GO:0032432 actin filament bundle
6.89 8.53e-07 GO:0005604 basement membrane
6.82 1.57e-02 GO:0042641 actomyosin
5.15 3.87e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
4.98 5.11e-04 GO:0030027 lamellipodium
4.31 7.92e-13 GO:0005578 proteinaceous extracellular matrix
3.92 2.44e-12 GO:0031012 extracellular matrix
3.06 1.26e-02 GO:0031252 cell leading edge
2.03 3.42e-05 GO:0044421 extracellular region part
1.48 1.63e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
26.32 4.72e-10 GO:0048407 platelet-derived growth factor binding
7.64 1.23e-09 GO:0005201 extracellular matrix structural constituent
4.21 2.06e-03 GO:0019838 growth factor binding
4.10 5.88e-03 GO:0004222 metalloendopeptidase activity
3.55 4.23e-03 GO:0003714 transcription corepressor activity
2.08 2.39e-05 GO:0001071 nucleic acid binding transcription factor activity
2.08 2.39e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.79 1.09e-02 GO:0030528 transcription regulator activity
1.46 2.22e-02 GO:0003677 DNA binding
1.29 1.08e-05 GO:0005515 protein binding
1.15 7.34e-05 GO:0005488 binding