Motif ID: AGCUGCC

Z-value: 1.018


Mature miRNA associated with seed AGCUGCC:

NamemiRBase Accession
hsa-miR-22 MIMAT0000077



Activity profile for motif AGCUGCC.

activity profile for motif AGCUGCC


Sorted Z-values histogram for motif AGCUGCC

Sorted Z-values for motif AGCUGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUGCC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_204380903 21.729 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr14_+_92790151 16.371 NM_153646
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92789536 16.072 NM_153647
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr14_+_92788924 14.626 NM_153648
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_+_24882565 14.184 NM_001010980
 C1orf130
chromosome 1 open reading frame 130
chr1_-_35325335 13.587 NM_001164825
NM_138428
 C1orf212

chromosome 1 open reading frame 212

chr18_-_74729049 13.442 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein



chr1_-_35324645 12.410 NM_001164824
 C1orf212
chromosome 1 open reading frame 212
chr22_+_31031672 12.039 NM_001001479
 SLC35E4
solute carrier family 35, member E4
chr1_+_192778168 9.887 NM_002923
 RGS2
regulator of G-protein signaling 2, 24kDa
chr10_-_120514669 8.972 NM_153810
 C10orf46
chromosome 10 open reading frame 46
chr16_-_4292052 8.514 NM_001098814
 SRL
sarcalumenin
chr19_-_5680910 8.430 NM_205767
 C19orf70
chromosome 19 open reading frame 70
chr2_+_226265601 8.319 NM_020864
 NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr15_+_42867708 7.985 NM_020759
 STARD9
StAR-related lipid transfer (START) domain containing 9
chr1_+_12227050 7.439 NM_001066
 TNFRSF1B
tumor necrosis factor receptor superfamily, member 1B
chr6_+_41040687 7.081 NM_002505
NM_021705
 NFYA

nuclear transcription factor Y, alpha

chr2_+_17721806 6.805 NM_003385
 VSNL1
visinin-like 1
chr20_+_37434294 6.523 NM_001172735
NM_015568
 PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr5_-_175964223 6.385 NM_014901
 RNF44
ring finger protein 44

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.28 1.17e-02 GO:0006468 protein phosphorylation
2.28 3.05e-02 GO:0010628 positive regulation of gene expression
2.08 1.19e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.86 4.09e-02 GO:0051239 regulation of multicellular organismal process
1.79 3.52e-03 GO:0006464 protein modification process
1.75 4.02e-02 GO:0023051 regulation of signaling
1.73 1.04e-02 GO:0043412 macromolecule modification
1.70 2.72e-02 GO:0048583 regulation of response to stimulus
1.65 4.78e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.65 6.12e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.64 4.35e-03 GO:0010468 regulation of gene expression
1.63 2.36e-02 GO:0051252 regulation of RNA metabolic process
1.63 4.07e-02 GO:0006355 regulation of transcription, DNA-dependent
1.62 3.86e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59 1.88e-04 GO:0031323 regulation of cellular metabolic process
1.59 1.12e-02 GO:0009889 regulation of biosynthetic process
1.59 1.31e-02 GO:0031326 regulation of cellular biosynthetic process
1.58 1.29e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.57 2.14e-02 GO:0048518 positive regulation of biological process
1.55 3.00e-03 GO:0060255 regulation of macromolecule metabolic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
33.51 1.42e-02 GO:0000900 translation repressor activity, nucleic acid binding
22.34 5.24e-03 GO:0030371 translation repressor activity
10.16 3.44e-02 GO:0015491 cation:cation antiporter activity
6.38 3.34e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
6.26 1.62e-05 GO:0005057 receptor signaling protein activity
2.67 3.13e-03 GO:0004674 protein serine/threonine kinase activity
2.52 4.02e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.46 9.66e-04 GO:0004672 protein kinase activity
2.35 2.46e-04 GO:0016301 kinase activity
2.23 7.55e-03 GO:0043565 sequence-specific DNA binding
2.12 7.64e-04 GO:0001071 nucleic acid binding transcription factor activity
2.12 7.64e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.08 3.39e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.69 3.08e-02 GO:0030554 adenyl nucleotide binding
1.67 4.99e-02 GO:0032559 adenyl ribonucleotide binding
1.27 6.03e-03 GO:0005515 protein binding