Motif ID: AGCUUAU

Z-value: 0.818


Mature miRNA associated with seed AGCUUAU:

NamemiRBase Accession
hsa-miR-21 MIMAT0000076
hsa-miR-590-5p MIMAT0003258



Activity profile for motif AGCUUAU.

activity profile for motif AGCUUAU


Sorted Z-values histogram for motif AGCUUAU

Sorted Z-values for motif AGCUUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_18466759 10.406 NM_001195470
NM_002971
 SATB1

SATB homeobox 1

chr7_-_139876718 9.884 NM_030647
 JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr5_+_67586466 9.402 NM_181504
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_18480203 8.995 NM_001131010
 SATB1
SATB homeobox 1
chr10_+_112631552 8.462 NM_001199492
NM_014456
NM_145341
 PDCD4


programmed cell death 4 (neoplastic transformation inhibitor)


chr22_+_33196801 8.019 NM_000362
 TIMP3
TIMP metallopeptidase inhibitor 3
chr5_+_67584251 7.174 NM_181524
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_67511578 7.019 NM_181523
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr5_+_67588395 6.553 NM_001242466
 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr22_+_40573879 6.434 NM_001162501
NM_015088
 TNRC6B

trinucleotide repeat containing 6B

chr2_-_64371444 5.539 NM_020651
 PELI1
pellino homolog 1 (Drosophila)
chr22_+_40440664 5.182 NM_001024843
 TNRC6B
trinucleotide repeat containing 6B
chr10_-_3827418 5.120 NM_001160124
NM_001160125
NM_001300
 KLF6


Kruppel-like factor 6


chr15_-_38856830 5.040 NM_001128602
NM_005739
 RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr18_-_29523087 4.815 NM_014939
 TRAPPC8
trafficking protein particle complex 8
chr4_-_89744154 4.697 NM_001015045
 FAM13A
family with sequence similarity 13, member A
chr1_+_203274646 4.692 NM_006763
 BTG2
BTG family, member 2
chr3_+_152017193 4.564 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
 MBNL1




muscleblind-like (Drosophila)




chr3_+_30647901 4.481 NM_001024847
NM_003242
 TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr8_+_98881277 4.359 NM_002380
NM_030583
 MATN2

matrilin 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 72 entries
enrichment   p-value GO term description
29.20 7.90e-03 GO:0032925 regulation of activin receptor signaling pathway
15.82 1.89e-03 GO:0045768 positive regulation of anti-apoptosis
14.14 5.66e-04 GO:0030510 regulation of BMP signaling pathway
12.94 6.38e-03 GO:0045767 regulation of anti-apoptosis
12.94 6.38e-03 GO:0060021 palate development
8.08 6.70e-03 GO:0030278 regulation of ossification
6.61 2.95e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
4.91 6.64e-03 GO:0051241 negative regulation of multicellular organismal process
4.71 1.02e-02 GO:0030334 regulation of cell migration
4.65 1.15e-02 GO:2000145 regulation of cell motility
4.58 1.35e-02 GO:0001568 blood vessel development
4.25 2.81e-02 GO:0001944 vasculature development
4.25 2.81e-02 GO:0040012 regulation of locomotion
4.24 2.91e-02 GO:0051270 regulation of cellular component movement
4.12 1.83e-02 GO:0051093 negative regulation of developmental process
4.01 2.41e-02 GO:0045597 positive regulation of cell differentiation
3.72 7.12e-03 GO:0051094 positive regulation of developmental process
3.53 1.37e-02 GO:0072358 cardiovascular system development
3.53 1.37e-02 GO:0072359 circulatory system development
3.41 5.33e-04 GO:0045595 regulation of cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.58 8.03e-05 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
12.66 1.37e-03 GO:0046332 SMAD binding
7.10 3.28e-03 GO:0019838 growth factor binding
3.10 8.18e-04 GO:0043565 sequence-specific DNA binding
3.07 7.22e-06 GO:0001071 nucleic acid binding transcription factor activity
3.07 7.22e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
2.01 4.17e-04 GO:0003677 DNA binding
1.81 2.79e-04 GO:0003676 nucleic acid binding
1.48 3.16e-05 GO:0005515 protein binding
1.21 4.59e-03 GO:0005488 binding