Motif ID: AGUGCAA

Z-value: 1.127


Mature miRNA associated with seed AGUGCAA:

NamemiRBase Accession
hsa-miR-130a MIMAT0000425
hsa-miR-130b MIMAT0000691
hsa-miR-301a MIMAT0000688
hsa-miR-301b MIMAT0004958
hsa-miR-3666 MIMAT0018088
hsa-miR-4295 MIMAT0016844
hsa-miR-454 MIMAT0003885



Activity profile for motif AGUGCAA.

activity profile for motif AGUGCAA


Sorted Z-values histogram for motif AGUGCAA

Sorted Z-values for motif AGUGCAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCAA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_60337350 31.661 NM_021136
 RTN1
reticulon 1
chr20_+_10199455 29.206 NM_003081
NM_130811
 SNAP25

synaptosomal-associated protein, 25kDa

chr14_-_60097531 29.028 NM_206852
 RTN1
reticulon 1
chr8_+_26435339 19.639 NM_001386
 DPYSL2
dihydropyrimidinase-like 2
chr20_+_44650260 19.201 NM_001134771
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr8_+_26371461 18.494 NM_001197293
 DPYSL2
dihydropyrimidinase-like 2
chr20_+_44657812 17.898 NM_020708
 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr14_-_21493910 17.774 NM_016250
NM_201535
NM_201536
NM_201537
 NDRG2



NDRG family member 2



chr3_+_115342150 16.757 NM_001130064
NM_002045
 GAP43

growth associated protein 43

chr14_-_21493122 16.254 NM_201538
NM_201539
NM_201540
NM_201541
 NDRG2



NDRG family member 2



chr1_-_204380903 15.944 NM_032833
 PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr2_+_131674223 15.874 NM_015320
NM_032995
 ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr8_-_110657025 14.181 NM_001099753
NM_001099754
NM_001099755
 SYBU


syntabulin (syntaxin-interacting)


chr8_-_110704019 14.019 NM_001099743
NM_001099744
 SYBU

syntabulin (syntaxin-interacting)

chr17_-_78450247 13.809 NM_002522
 NPTX1
neuronal pentraxin I
chr1_+_160085519 13.766 NM_000702
 ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr15_-_83316621 13.664 NM_030594
 CPEB1
cytoplasmic polyadenylation element binding protein 1
chr16_-_57318574 13.644 NM_015993
 PLLP
plasmolipin
chr11_-_45687135 13.559 NM_003654
 CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr8_-_110693233 13.281 NM_001099745
NM_001099746
 SYBU

syntabulin (syntaxin-interacting)


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 71 entries
enrichment   p-value GO term description
16.08 1.60e-03 GO:0021846 cell proliferation in forebrain
3.21 5.34e-04 GO:0007420 brain development
3.03 2.76e-05 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.94 2.97e-02 GO:0033674 positive regulation of kinase activity
2.92 2.23e-06 GO:0007167 enzyme linked receptor protein signaling pathway
2.90 2.29e-02 GO:0070647 protein modification by small protein conjugation or removal
2.85 4.59e-02 GO:0051347 positive regulation of transferase activity
2.79 7.41e-04 GO:0007417 central nervous system development
2.78 1.29e-03 GO:0019226 transmission of nerve impulse
2.78 1.29e-03 GO:0035637 multicellular organismal signaling
2.71 7.63e-03 GO:0008283 cell proliferation
2.59 3.07e-12 GO:0007399 nervous system development
2.55 9.61e-06 GO:0048699 generation of neurons
2.53 4.03e-04 GO:0030182 neuron differentiation
2.46 2.09e-05 GO:0022008 neurogenesis
2.42 3.86e-02 GO:0010647 positive regulation of cell communication
2.40 4.30e-02 GO:0023056 positive regulation of signaling
2.38 1.73e-03 GO:0006468 protein phosphorylation
2.34 1.76e-05 GO:0010646 regulation of cell communication
2.31 3.36e-03 GO:0007267 cell-cell signaling

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
6.35 7.83e-03 GO:0031901 early endosome membrane
4.50 3.08e-04 GO:0005769 early endosome
3.48 4.40e-02 GO:0045121 membrane raft
2.39 1.89e-02 GO:0005768 endosome
1.14 1.39e-02 GO:0005622 intracellular
1.14 3.36e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
7.35 4.39e-02 GO:0004843 ubiquitin-specific protease activity
2.66 2.04e-03 GO:0004674 protein serine/threonine kinase activity
2.61 4.85e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.43 3.56e-05 GO:0016301 kinase activity
2.36 2.17e-03 GO:0004672 protein kinase activity
2.22 6.58e-05 GO:0001071 nucleic acid binding transcription factor activity
2.22 6.58e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
2.20 6.64e-03 GO:0043565 sequence-specific DNA binding
2.15 6.79e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.03 1.75e-03 GO:0030528 transcription regulator activity
1.77 3.61e-03 GO:0030554 adenyl nucleotide binding
1.75 6.03e-03 GO:0032559 adenyl ribonucleotide binding
1.74 7.54e-03 GO:0005524 ATP binding
1.66 6.34e-03 GO:0017076 purine nucleotide binding
1.64 9.80e-03 GO:0032553 ribonucleotide binding
1.64 9.80e-03 GO:0032555 purine ribonucleotide binding
1.62 1.97e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.36 1.54e-06 GO:0005515 protein binding
1.19 3.93e-06 GO:0005488 binding