Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.047


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARNT2chr15_+_80696569-0.483.2e-14Click!
AHRchr7_+_173381820.314.2e-06Click!
ARNTchr1_-_150849211-0.045.9e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_151151514 34.815 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151516 29.043 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151151462 27.757 NM_005754
NM_198395
 G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr5_+_151151511 25.340 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr21_-_40720938 22.053 HMGN1
high mobility group nucleosome binding domain 1
chr6_-_86352650 20.457 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr19_+_17666457 19.256 GLT25D1
glycosyltransferase 25 domain containing 1
chr15_-_69113213 18.968 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr15_-_69113089 18.244 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr6_-_86352656 18.229 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr20_-_33872505 18.170 NM_181468
 EIF6
eukaryotic translation initiation factor 6
chr12_-_46662533 18.100 SLC38A1
solute carrier family 38, member 1
chr20_-_33872289 17.102 EIF6
eukaryotic translation initiation factor 6
chr3_+_52719935 16.852 NM_014366
NM_206825
NM_206826
 GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr5_+_170814707 16.796 NM_001037738
NM_002520
NM_199185
 NPM1


nucleophosmin (nucleolar phosphoprotein B23, numatrin)


chr4_-_103748649 15.875 NM_181887
NM_181891
 UBE2D3

ubiquitin-conjugating enzyme E2D 3

chr6_-_86352635 15.863 NM_001159673
 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_64798050 15.847 NM_007235
 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_86352982 15.744 NM_001159677
NM_006372
 SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr6_-_86352564 15.714 NM_001159674
NM_001253771
 SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 169 entries
enrichment   p-value GO term description
4.44 5.20e-05 GO:0006413 translational initiation
3.83 1.74e-02 GO:0042278 purine nucleoside metabolic process
3.83 1.74e-02 GO:0046128 purine ribonucleoside metabolic process
3.56 6.95e-07 GO:0019080 viral genome expression
3.56 6.95e-07 GO:0019083 viral transcription
3.51 1.08e-11 GO:0019058 viral infectious cycle
3.48 4.28e-03 GO:0051701 interaction with host
3.46 2.04e-13 GO:0022415 viral reproductive process
3.32 7.68e-07 GO:0006414 translational elongation
3.32 9.02e-06 GO:0006415 translational termination
3.23 7.98e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
3.13 2.39e-06 GO:0032984 macromolecular complex disassembly
3.13 2.39e-06 GO:0034623 cellular macromolecular complex disassembly
3.13 7.60e-03 GO:0031124 mRNA 3'-end processing
3.11 2.79e-05 GO:0043241 protein complex disassembly
3.11 2.79e-05 GO:0043624 cellular protein complex disassembly
3.02 1.15e-18 GO:0006412 translation
3.01 1.02e-03 GO:0051168 nuclear export
2.99 1.70e-02 GO:0006405 RNA export from nucleus
2.92 3.14e-03 GO:0022618 ribonucleoprotein complex assembly

Gene overrepresentation in compartment category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
6.57 6.00e-06 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.67 2.00e-02 GO:0031519 PcG protein complex
3.87 2.38e-02 GO:0001725 stress fiber
3.73 3.77e-03 GO:0022625 cytosolic large ribosomal subunit
3.46 3.29e-06 GO:0022626 cytosolic ribosome
3.07 2.76e-03 GO:0015934 large ribosomal subunit
2.87 3.42e-10 GO:0005840 ribosome
2.87 1.09e-03 GO:0071013 catalytic step 2 spliceosome
2.72 1.04e-25 GO:0030529 ribonucleoprotein complex
2.58 5.60e-05 GO:0005681 spliceosomal complex
2.47 5.69e-05 GO:0044445 cytosolic part
2.01 5.49e-26 GO:0005654 nucleoplasm
2.01 4.66e-04 GO:0005759 mitochondrial matrix
1.98 3.83e-03 GO:0016604 nuclear body
1.92 1.27e-31 GO:0031981 nuclear lumen
1.91 5.51e-03 GO:0005667 transcription factor complex
1.90 6.86e-39 GO:0070013 intracellular organelle lumen
1.90 5.33e-07 GO:0005730 nucleolus
1.89 1.60e-39 GO:0031974 membrane-enclosed lumen
1.89 1.24e-38 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
3.90 6.48e-05 GO:0003743 translation initiation factor activity
3.87 3.95e-02 GO:0003727 single-stranded RNA binding
3.85 8.62e-04 GO:0043021 ribonucleoprotein binding
2.92 7.72e-04 GO:0008135 translation factor activity, nucleic acid binding
2.88 7.08e-08 GO:0003735 structural constituent of ribosome
2.62 2.30e-02 GO:0031625 ubiquitin protein ligase binding
2.44 5.07e-03 GO:0051082 unfolded protein binding
2.29 9.18e-25 GO:0003723 RNA binding
1.83 9.35e-03 GO:0008134 transcription factor binding
1.58 6.01e-03 GO:0005198 structural molecule activity
1.53 1.31e-02 GO:0046983 protein dimerization activity
1.51 4.48e-13 GO:0000166 nucleotide binding
1.46 1.91e-03 GO:0030528 transcription regulator activity
1.42 2.17e-46 GO:0005515 protein binding
1.41 4.13e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.39 3.35e-12 GO:0003676 nucleic acid binding
1.38 3.99e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.37 1.80e-03 GO:0005524 ATP binding
1.36 1.16e-04 GO:0017076 purine nucleotide binding
1.36 1.62e-04 GO:0032553 ribonucleotide binding