Motif ID: ALX1.p2

Z-value: 1.644


Transcription factors associated with ALX1.p2:

Gene SymbolEntrez IDGene Name
ALX1 8092 ALX homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ALX1chr12_+_85673884-0.045.9e-01Click!


Activity profile for motif ALX1.p2.

activity profile for motif ALX1.p2


Sorted Z-values histogram for motif ALX1.p2

Sorted Z-values for motif ALX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_13835313 63.756 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr20_+_34556528 40.369 NM_001207076
NM_080834
C20orf152

chromosome 20 open reading frame 152

chr19_-_21646685 34.645


chr9_-_4742042 31.399 NM_001199853
AK3
adenylate kinase 3
chr19_+_21264952 30.040 NM_182515
ZNF714
zinc finger protein 714
chr1_+_155853546 29.845 SYT11
synaptotagmin XI
chr11_-_117748200 29.731 NM_001164831
FXYD6
FXYD domain containing ion transport regulator 6
chr5_+_36608430 25.916 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_111717585 25.678 NM_001008272
NM_013259
TAGLN3

transgelin 3

chr19_+_12203077 25.398 ZNF788
zinc finger family member 788
chr17_-_29641068 24.417 EVI2B
ecotropic viral integration site 2B
chr3_-_194072004 23.817 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr8_-_33457491 23.362 DUSP26
dual specificity phosphatase 26 (putative)
chr12_+_101988746 23.272 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr6_-_41254392 22.849 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr10_-_28571014 22.767 NM_173496
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_151739130 22.488 NM_016178
OAZ3
ornithine decarboxylase antizyme 3
chr5_+_36606667 21.923 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr18_+_21572736 21.289 NM_153211
TTC39C
tetratricopeptide repeat domain 39C
chr10_+_49609641 21.286 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
7.37 4.79e-02 GO:0060338 regulation of type I interferon-mediated signaling pathway
2.41 5.04e-06 GO:0006955 immune response
2.38 1.11e-02 GO:0050776 regulation of immune response
1.99 3.31e-05 GO:0002376 immune system process
1.98 2.19e-02 GO:0007267 cell-cell signaling
1.97 1.31e-02 GO:0006952 defense response
1.94 1.87e-03 GO:0007154 cell communication
1.39 7.34e-03 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
3.51 5.23e-03 GO:0034703 cation channel complex
2.73 2.41e-02 GO:0034702 ion channel complex
2.32 3.44e-11 GO:0005887 integral to plasma membrane
2.30 3.59e-11 GO:0031226 intrinsic to plasma membrane
2.25 5.84e-06 GO:0005615 extracellular space
2.22 8.64e-08 GO:0044421 extracellular region part
1.90 7.04e-10 GO:0005576 extracellular region
1.83 4.93e-09 GO:0044459 plasma membrane part
1.47 1.02e-06 GO:0005886 plasma membrane
1.46 1.81e-06 GO:0071944 cell periphery
1.25 1.45e-02 GO:0031224 intrinsic to membrane
1.25 1.89e-02 GO:0016021 integral to membrane
1.22 2.41e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
15.78 2.40e-02 GO:0005132 interferon-alpha/beta receptor binding
5.49 3.26e-02 GO:0008009 chemokine activity
3.74 1.97e-05 GO:0005125 cytokine activity
3.51 4.16e-04 GO:0005126 cytokine receptor binding
2.63 1.34e-02 GO:0005261 cation channel activity
2.24 3.14e-02 GO:0005216 ion channel activity
2.22 2.76e-02 GO:0015267 channel activity
2.21 2.88e-02 GO:0022803 passive transmembrane transporter activity
2.20 4.07e-02 GO:0022838 substrate-specific channel activity
1.56 1.59e-02 GO:0004872 receptor activity
1.49 2.03e-02 GO:0004871 signal transducer activity
1.49 2.03e-02 GO:0060089 molecular transducer activity