Motif ID: AR.p2

Z-value: 1.533


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARchrX_+_66763868,
chrX_+_66788682
0.337.3e-07Click!


Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_107131217 110.930 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_106926393 66.565 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106573348 48.266 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106691698 45.055


chr14_-_106725620 40.870 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr1_+_22979681 40.772 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr3_-_58563070 39.358 FAM107A
family with sequence similarity 107, member A
chr1_-_150738232 34.975 CTSS
cathepsin S
chr14_-_107113943 33.223 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106994001 32.419 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr3_-_58563490 28.958 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr14_-_106518424 27.900 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr14_-_106692107 26.945 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_107048697 25.907 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106552313 21.536 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_21493858 20.625 NDRG2
NDRG family member 2
chr8_+_100025534 19.762 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr1_-_150738255 19.696 CTSS
cathepsin S
chr14_-_65346554 16.184 SPTB
spectrin, beta, erythrocytic
chr19_+_39899749 13.631


chr14_-_107218786 12.462 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_107099379 12.034 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr8_+_100025493 10.483 NM_015243
NM_017890
NM_152564
NM_181661
VPS13B



vacuolar protein sorting 13 homolog B (yeast)



chr1_-_150738292 10.249 NM_001199739
NM_004079
CTSS

cathepsin S

chr14_-_106725232 10.037 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr5_-_149792276 9.024 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr14_-_21493910 8.444 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr14_-_107199126 8.055 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr19_+_35630391 7.473 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr8_+_100025501 7.428 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr6_-_6320897 7.409 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr14_-_106610338 7.000 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_20250051 6.803 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr21_-_35884503 6.802 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr11_+_117070039 6.511 NM_001001522
NM_003186
TAGLN

transgelin

chr6_-_6320875 5.920 F13A1
coagulation factor XIII, A1 polypeptide
chr1_+_104292278 5.889 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr19_-_54876671 5.694 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr14_-_23623493 5.672 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chrX_+_150345055 5.505 NM_004224
GPR50
G protein-coupled receptor 50
chr14_-_106586333 5.475 IGHV4-31
immunoglobulin heavy variable 4-31
chr12_+_51318515 5.398 NM_014033
METTL7A
methyltransferase like 7A
chr11_-_64528186 5.283 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr1_-_104239071 4.934 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr4_+_154178525 4.695 TRIM2
tripartite motif containing 2
chr1_+_104198140 4.618 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr10_-_116444112 4.612 ABLIM1
actin binding LIM protein 1
chr9_-_77502635 4.543 NM_001177310
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr10_+_70847817 4.343 NM_002727
SRGN
serglycin
chr1_-_156786500 4.167 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr6_-_26235160 4.039 NM_005320
HIST1H1D
histone cluster 1, H1d
chr16_-_20338808 3.958 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr11_+_74862031 3.799 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr4_+_159593233 3.721 NM_004453
ETFDH
electron-transferring-flavoprotein dehydrogenase
chrX_-_6453158 3.708 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr1_+_13716087 3.651 NM_001099851
PRAMEF17
PRAME family member 17
chr1_+_13495253 3.448 NM_001045480
PRAMEF17
PRAMEF16
PRAME family member 17
PRAME family member 16
chr1_-_202129705 3.284 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_27953046 3.252 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr7_-_150946031 3.180 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_-_7245048 3.137 C1R
complement component 1, r subcomponent
chr15_-_90349819 3.135 ANPEP
alanyl (membrane) aminopeptidase
chr11_-_72433379 3.071 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chrX_+_152082985 2.776 NM_001178106
NM_001178107
NM_001178108
NM_001178109
NM_001178110
NM_007150
ZNF185





zinc finger protein 185 (LIM domain)





chrX_+_8432870 2.705 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr7_+_87563432 2.622 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr3_-_120401401 2.337 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr12_-_91505541 2.181 NM_002345
LUM
lumican
chr1_-_149982528 2.158 NM_020205
OTUD7B
OTU domain containing 7B
chr1_-_153588789 2.140 NM_020672
S100A14
S100 calcium binding protein A14
chr13_+_113777112 2.122 NM_000504
F10
coagulation factor X
chr16_-_787888 2.108 NARFL
nuclear prelamin A recognition factor-like
chrY_-_26194115 2.090 NM_001003894
NM_001003895
NM_004680
NM_170723
CDY1B

CDY1

chromodomain protein, Y-linked, 1B

chromodomain protein, Y-linked, 1

chr1_-_156460390 2.058 MEF2D
myocyte enhancer factor 2D
chr18_+_12991329 1.984 NM_032142
CEP192
centrosomal protein 192kDa
chr11_-_113577023 1.972 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr1_-_173174611 1.961 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr19_-_15391261 1.933 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr5_-_149324282 1.853 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr14_+_85999464 1.848


chr2_-_109605668 1.741 NM_022336
EDAR
ectodysplasin A receptor
chr14_+_21467413 1.682 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr9_-_130617009 1.634 NM_000118
NM_001114753
ENG

endoglin

chr9_+_21440452 1.575 NM_024013
IFNA1
interferon, alpha 1
chr2_+_88472657 1.503 NM_018271
THNSL2
threonine synthase-like 2 (S. cerevisiae)
chr14_-_106791054 1.468 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr15_+_85291802 1.465 NM_014630
ZNF592
zinc finger protein 592
chr12_+_113416267 1.400 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chrY_+_20137666 1.371 NM_001001722
NM_004825
CDY2B
CDY2A
chromodomain protein, Y-linked, 2B
chromodomain protein, Y-linked, 2A
chr17_+_37824506 1.349 NM_002686
PNMT
phenylethanolamine N-methyltransferase
chrY_-_19992072 1.335 NM_001001722
NM_004825
CDY2B
CDY2A
chromodomain protein, Y-linked, 2B
chromodomain protein, Y-linked, 2A
chr1_+_153388999 1.335 NM_176823
S100A7A
S100 calcium binding protein A7A
chr4_-_10686314 1.243 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chrY_+_27768241 1.196 NM_001003894
NM_001003895
NM_004680
NM_170723
CDY1B

CDY1

chromodomain protein, Y-linked, 1B

chromodomain protein, Y-linked, 1

chr11_+_45115563 1.151 NM_020229
PRDM11
PR domain containing 11
chr5_-_58571916 1.067 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_156785938 1.042 NM_001161443
SH2D2A
SH2 domain containing 2A
chr20_-_23731558 1.001 NM_001898
CST1
cystatin SN
chr3_-_50608421 0.983 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr7_+_65420507 0.914 VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr8_-_7417233 0.901 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr14_+_21156922 0.844 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr2_+_242576975 0.756 NM_013325
NM_178326
ATG4B

ATG4 autophagy related 4 homolog B (S. cerevisiae)

chr15_+_59908908 0.748 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_+_242577098 0.690 ATG4B
ATG4 autophagy related 4 homolog B (S. cerevisiae)
chr10_-_62332666 0.638 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_+_94139331 0.601 CASD1
CAS1 domain containing 1
chr7_+_20655244 0.520 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr8_+_7626498 0.511 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr8_+_7152535 0.489 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr17_-_48264039 0.471 COL1A1
collagen, type I, alpha 1
chr1_-_1149495 0.440 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr18_+_72166568 0.429 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr20_-_42816217 0.404 NM_020433
NM_175913
JPH2

junctophilin 2

chr19_+_55417507 0.400 NM_001145457
NM_001145458
NM_001242356
NM_001242357
NM_004829
NCR1




natural cytotoxicity triggering receptor 1




chr9_-_75568232 0.322 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr17_-_3496122 0.318 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr19_+_50472856 0.286 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr8_+_7144913 0.284 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr8_-_7440174 0.279 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr8_+_7114425 0.265 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr5_+_67588395 0.222 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_155312448 0.172 NM_017639
DCHS2
dachsous 2 (Drosophila)
chr8_+_7137291 0.126 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr20_-_42815732 0.101 JPH2
junctophilin 2
chr6_+_29079586 0.086 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr3_+_46448678 0.070 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr8_+_7572964 0.043 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.34 1.61e-04 GO:0002376 immune system process
3.98 9.61e-04 GO:0006955 immune response
46.07 1.70e-02 GO:0050710 negative regulation of cytokine secretion
4.09 3.59e-02 GO:0001775 cell activation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
33.78 8.14e-09 GO:0003823 antigen binding