• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 3.162

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_58146108	302.760		CDK4	cyclin-dependent kinase 4
chr12_-_58146110	299.674		CDK4	cyclin-dependent kinase 4
chr12_-_58146025	299.008		CDK4	cyclin-dependent kinase 4
chr12_-_58146118	271.636	NM_000075	CDK4	cyclin-dependent kinase 4
chr2_-_10588451	157.598	NM_002539	ODC1	ornithine decarboxylase 1
chr14_+_20923341	135.218		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr8_+_98656428	112.966		MTDH	metadherin
chr2_+_216176818	104.570		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr14_+_20923289	102.646	NM_001244249 NM_001641 NM_080648 NM_080649	APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr19_+_10765106	101.532		ILF3	interleukin enhancer binding factor 3, 90kDa
chr2_+_216176808	101.483		ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr8_+_98656329	101.007	NM_178812	MTDH	metadherin
chr1_-_26232890	99.249	NM_001145454 NM_005563	STMN1	stathmin 1
chr8_+_98656494	95.044		MTDH	metadherin
chr3_+_158519911	92.531		MFSD1	major facilitator superfamily domain containing 1
chr14_+_20923705	90.389		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr4_-_100871431	89.802		H2AFZ	H2A histone family, member Z
chr3_+_158519888	88.588		MFSD1	major facilitator superfamily domain containing 1
chr6_-_43197178	82.437	NM_006443 NM_199184	C6orf108	chromosome 6 open reading frame 108
chr17_+_49337882	81.503		UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr17_+_49337892	80.759	NM_016001	UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr14_+_20923364	78.719		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chrX_+_100663205	78.387		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_+_113403433	77.558	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr17_+_49337909	76.232		UTP18	UTP18 small subunit (SSU) processome component homolog (yeast)
chr6_+_160390128	75.632	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr1_+_44440642	75.591		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr4_-_100871482	75.078	NM_002106	H2AFZ	H2A histone family, member Z
chr11_-_64014381	73.952		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr6_-_109703661	71.100		CD164	CD164 molecule, sialomucin
chr3_-_112280764	71.043		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr17_+_49230954	70.476		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr3_+_127317271	70.199		MCM2	minichromosome maintenance complex component 2
chrX_-_100662905	69.660	NM_000169	GLA	galactosidase, alpha
chr7_-_99698993	69.204		MCM7	minichromosome maintenance complex component 7
chr11_-_64014264	69.109		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr11_-_64014407	68.466	NM_138689	PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr3_+_127317274	68.300		MCM2	minichromosome maintenance complex component 2
chr7_-_99699030	67.218		MCM7	minichromosome maintenance complex component 7
chr1_+_44440623	66.928		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr10_+_124913884	66.616		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr1_+_44440673	66.191		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr19_+_49458151	65.819		BAX	BCL2-associated X protein
chrX_+_100663229	65.605		HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr6_+_36562135	65.365		SRSF3	serine/arginine-rich splicing factor 3
chr4_-_99850280	64.969		EIF4E	eukaryotic translation initiation factor 4E
chrX_-_100662788	64.504		GLA	galactosidase, alpha
chr2_+_109204745	64.180	NM_004987	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_+_44440595	63.654	NM_001039457 NM_004047	ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_+_158519877	63.042		MFSD1	major facilitator superfamily domain containing 1
chr20_+_44519965	62.977		CTSA	cathepsin A
chr17_+_49230929	62.832		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr3_+_158519714	62.508	NM_001167903 NM_022736	MFSD1	major facilitator superfamily domain containing 1
chr20_+_44520021	62.296		CTSA	cathepsin A
chr19_+_50180408	62.090	NM_001207042 NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr3_+_127317212	61.663	NM_004526	MCM2	minichromosome maintenance complex component 2
chr1_-_154531083	60.731	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr2_+_27440342	60.204		CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr1_-_115259381	60.193		NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog
chr1_-_26233367	59.878	NM_203399	STMN1	stathmin 1
chr11_-_64014140	59.732		PPP1R14B	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_10588273	59.661		ODC1	ornithine decarboxylase 1
chr4_-_100871418	59.539		H2AFZ	H2A histone family, member Z
chr17_+_49244082	59.283	NM_001018138	NME2	non-metastatic cells 2, protein (NM23B) expressed in
chr17_+_46970128	58.691	NM_001002027 NM_005175	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)
chr19_+_47634118	58.542		SAE1	SUMO1 activating enzyme subunit 1
chr7_-_99698916	58.318		MCM7	minichromosome maintenance complex component 7
chr11_+_61560108	58.141	NM_004111	FEN1	flap structure-specific endonuclease 1
chr20_+_44519924	57.885		CTSA	cathepsin A
chr10_+_75936524	57.681		ADK	adenosine kinase
chr4_+_57301898	57.605	NM_006452	PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_47634133	57.553		SAE1	SUMO1 activating enzyme subunit 1
chr21_-_46237978	56.375		SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr10_+_75936546	56.238		ADK	adenosine kinase
chr19_+_8509869	55.934		HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr4_+_57302448	55.869		PAICS	phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr19_+_49458031	55.708	NM_004324 NM_138761 NM_138763 NM_138764	BAX	BCL2-associated X protein
chr9_-_34048887	55.706	NM_018449	UBAP2	ubiquitin associated protein 2
chr3_+_158519925	55.331		MFSD1	major facilitator superfamily domain containing 1
chr11_-_47664014	55.318	NM_014342	MTCH2	mitochondrial carrier 2
chr6_-_7313352	55.063	NM_003144	SSR1	signal sequence receptor, alpha
chr2_-_198364560	55.036		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr10_+_75936220	54.952	NM_001123 NM_001202449	ADK	adenosine kinase
chr19_+_49458129	54.401		BAX	BCL2-associated X protein
chr16_+_88923490	53.961	NM_016209	TRAPPC2L	trafficking protein particle complex 2-like
chr8_+_55047780	53.590	NM_014175	MRPL15	mitochondrial ribosomal protein L15
chr2_-_198364522	52.295		HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr15_+_44084517	52.289	NM_001199878	SERF2-C15ORF63 SERF2	SERF2-C15orf63 readthrough small EDRK-rich factor 2
chr6_-_109703703	51.680	NM_001142401 NM_001142402 NM_001142403 NM_001142404 NM_006016	CD164	CD164 molecule, sialomucin
chr6_-_33385814	51.059
chr2_-_198364623	51.031	NM_002156	HSPD1	heat shock 60kDa protein 1 (chaperonin)
chr2_+_216176678	50.841	NM_004044	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr19_+_47634148	50.625		SAE1	SUMO1 activating enzyme subunit 1
chr12_-_2986299	50.278	NM_001243088 NM_001243089 NM_021953 NM_202002 NM_202003	FOXM1	forkhead box M1
chr1_-_27226928	50.132		GPATCH3	G patch domain containing 3
chr4_-_47465719	49.897		COMMD8	COMM domain containing 8
chr21_-_46237974	49.727		SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr10_-_120840311	49.296	NM_003750	EIF3A	eukaryotic translation initiation factor 3, subunit A
chr6_+_36562139	48.625		SRSF3	serine/arginine-rich splicing factor 3
chr19_+_8509802	48.593	NM_005968 NM_031203	HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr4_-_47465646	47.263	NM_017845	COMMD8	COMM domain containing 8
chr12_+_104359557	46.627	NM_003211	TDG	thymine-DNA glycosylase
chr10_+_124913759	46.572	NM_001007793 NM_004725	BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr12_-_76953561	46.531	NM_001003712 NM_020841	OSBPL8	oxysterol binding protein-like 8
chr10_-_120840296	46.487		EIF3A	eukaryotic translation initiation factor 3, subunit A
chr19_+_797390	45.881	NM_002819 NM_031990 NM_031991 NM_175847	PTBP1	polypyrimidine tract binding protein 1
chr6_-_8102753	45.762	NM_001135650 NM_004280	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1
chr17_+_49230896	45.718	NM_000269 NM_198175 NM_001018136	NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr12_-_2986095	45.653		FOXM1	forkhead box M1
chr18_+_77866914	45.448	NM_014913	ADNP2	ADNP homeobox 2
chr1_+_214776494	44.989	NM_016343	CENPF	centromere protein F, 350/400kDa (mitosin)
chr1_-_154600446	44.984	NM_001025107	ADAR	adenosine deaminase, RNA-specific
chr1_-_11120081	44.540	NM_003132	SRM	spermidine synthase
chr1_-_183604885	44.270	NM_005717	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr6_-_33386064	44.253	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr1_-_183604850	43.936		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr10_+_75936443	43.875		ADK	adenosine kinase
chr17_+_49230938	43.163		NME1 NME1-NME2	non-metastatic cells 1, protein (NM23A) expressed in NME1-NME2 readthrough
chr5_+_133707105	43.079		UBE2B	ubiquitin-conjugating enzyme E2B
chr1_-_154600383	43.037		ADAR	adenosine deaminase, RNA-specific
chr1_+_43148359	42.717		YBX1	Y box binding protein 1
chr8_-_104427373	42.648	NM_030780	SLC25A32	solute carrier family 25, member 32
chr11_+_61560352	42.614		FEN1	flap structure-specific endonuclease 1
chr3_-_49066760	41.621		IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2
chr10_+_124913921	41.544		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr4_-_99850242	41.168	NM_001130678	EIF4E	eukaryotic translation initiation factor 4E
chr1_+_154193757	40.875		UBAP2L	ubiquitin associated protein 2-like
chr19_-_5720155	40.780		LONP1	lon peptidase 1, mitochondrial
chr1_-_26232643	40.282	NM_203401	STMN1	stathmin 1
chr1_-_115259433	40.246	NM_002524	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_+_34204647	39.770	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chrX_+_23685613	39.561		PRDX4	peroxiredoxin 4
chr19_+_47634044	39.470	NM_001145713 NM_001145714 NM_005500	SAE1	SUMO1 activating enzyme subunit 1
chr6_-_109703617	39.291		CD164	CD164 molecule, sialomucin
chr19_+_50180492	39.091		PRMT1	protein arginine methyltransferase 1
chr6_-_109703553	38.957		CD164	CD164 molecule, sialomucin
chr5_+_68530621	38.891	NM_001799	CDK7	cyclin-dependent kinase 7
chr9_-_116172658	38.855		POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr3_-_113465101	38.786	NM_025146	NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr21_-_46237966	38.776		SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr19_+_13049413	38.549	NM_004343	CALR	calreticulin
chr2_-_44223039	38.448		LRPPRC	leucine-rich PPR-motif containing
chr17_-_5342380	38.332		C1QBP	complement component 1, q subcomponent binding protein
chr18_+_158480	38.208	NM_001037334 NM_005151	USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chrX_+_23685658	37.928		PRDX4	peroxiredoxin 4
chr2_-_61764661	37.658		XPO1	exportin 1 (CRM1 homolog, yeast)
chr12_+_132413776	37.567	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr21_-_38445389	37.537	NM_153682	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr1_-_11120047	37.480		SRM	spermidine synthase
chr19_-_2427874	37.408	NM_012458	TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr8_+_98788014	37.365		LAPTM4B	lysosomal protein transmembrane 4 beta
chrX_+_23685637	37.297	NM_006406	PRDX4	peroxiredoxin 4
chr19_+_12848281	37.047	NM_004317	ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr11_+_18344113	37.004		GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr22_+_20105145	36.922		RANBP1	RAN binding protein 1
chr6_+_36562089	36.741	NM_003017	SRSF3	serine/arginine-rich splicing factor 3
chr2_-_44223131	36.704	NM_133259	LRPPRC	leucine-rich PPR-motif containing
chr1_-_78148326	36.659	NM_015534	ZZZ3	zinc finger, ZZ-type containing 3
chr1_+_33116748	36.441	NM_001135255 NM_005610 NM_001135256	RBBP4	retinoblastoma binding protein 4
chr5_+_68530713	36.297		CDK7	cyclin-dependent kinase 7
chr2_-_44223112	35.861		LRPPRC	leucine-rich PPR-motif containing
chr19_-_5720136	35.688		LONP1	lon peptidase 1, mitochondrial
chr16_+_31044414	35.513		STX4	syntaxin 4
chr1_+_111992105	35.268		ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1
chr6_-_28891409	35.237		TRIM27	tripartite motif containing 27
chrX_+_100663120	35.164	NM_001032393 NM_019597	HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')
chr2_-_26101301	34.818	NM_018263	ASXL2	additional sex combs like 2 (Drosophila)
chr10_+_22605300	34.791	NM_001204062 NM_012071	COMMD3-BMI1 COMMD3	COMMD3-BMI1 readthrough COMM domain containing 3
chr1_+_214776582	34.781		CENPF	centromere protein F, 350/400kDa (mitosin)
chr7_-_132766834	34.712		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_-_137911039	34.697		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr12_+_49658862	34.534	NM_032704	TUBA1C	tubulin, alpha 1c
chr19_-_13227212	34.502	NM_001142554 NM_017722 NM_001136035	TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)
chr12_-_65153189	34.500	NM_002076	GNS	glucosamine (N-acetyl)-6-sulfatase
chr10_+_124913862	34.354		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr19_+_8509594	34.184		HNRNPM	heterogeneous nuclear ribonucleoprotein M
chr12_-_76953259	34.129		OSBPL8	oxysterol binding protein-like 8
chr1_+_45477888	34.128		UROD	uroporphyrinogen decarboxylase
chr8_+_22224758	34.107	NM_001128431 NM_001135154 NM_015359	SLC39A14	solute carrier family 39 (zinc transporter), member 14
chr12_+_49658865	34.061		TUBA1C	tubulin, alpha 1c
chr20_+_44520203	33.979		CTSA	cathepsin A
chr1_-_183604793	33.942		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr7_-_132766697	33.879	NM_017812	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr2_+_109204777	33.789		LIMS1	LIM and senescent cell antigen-like domains 1
chr9_-_116172635	33.664		POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)
chr7_+_150759633	33.644	NM_001199693 NM_001199694	SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr12_-_49318663	33.450	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr13_+_76123885	33.444	NM_006002	UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr21_-_45196200	33.344	NM_000100	CSTB	cystatin B (stefin B)
chr3_-_112280359	33.301	NM_022488	ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr19_-_42806928	33.202	NM_001145939 NM_001145940	PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr1_-_155232091	33.040	NM_005698 NM_052837	SCAMP3	secretory carrier membrane protein 3
chr6_-_114292312	33.029	NM_001527	HDAC2	histone deacetylase 2
chr8_-_126103873	33.001		KIAA0196	KIAA0196
chr11_+_8008866	32.836	NM_003754	EIF3F	eukaryotic translation initiation factor 3, subunit F
chr2_+_178077421	32.836	NM_194247	HNRNPA3	heterogeneous nuclear ribonucleoprotein A3
chr19_+_41256758	32.794	NM_004596	SNRPA	small nuclear ribonucleoprotein polypeptide A
chr8_-_104427268	32.706		SLC25A32	solute carrier family 25, member 32
chr7_-_99699426	32.660	NM_005916	MCM7	minichromosome maintenance complex component 7
chr18_+_158586	32.587		USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.88	4.33e-31	GO:0034641	cellular nitrogen compound metabolic process
1.52	1.67e-30	GO:0044237	cellular metabolic process
1.84	1.22e-29	GO:0006807	nitrogen compound metabolic process
1.94	1.75e-29	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47	1.58e-25	GO:0044238	primary metabolic process
1.42	5.58e-25	GO:0008152	metabolic process
1.23	1.60e-22	GO:0009987	cellular process
1.59	4.79e-22	GO:0044260	cellular macromolecule metabolic process
1.87	3.88e-19	GO:0090304	nucleic acid metabolic process
1.48	1.20e-17	GO:0043170	macromolecule metabolic process
1.71	5.66e-14	GO:0044249	cellular biosynthetic process
1.81	2.88e-13	GO:0010467	gene expression
1.66	1.28e-12	GO:0009058	biosynthetic process
1.81	4.25e-12	GO:0016070	RNA metabolic process
1.69	4.87e-09	GO:0044281	small molecule metabolic process
1.45	7.99e-09	GO:0071840	cellular component organization or biogenesis
2.89	8.14e-09	GO:0006412	translation
2.25	8.26e-09	GO:0006396	RNA processing
1.56	9.93e-09	GO:0044267	cellular protein metabolic process
1.52	2.09e-08	GO:0071841	cellular component organization or biogenesis at cellular level
2.08	2.22e-08	GO:0046907	intracellular transport
2.29	5.25e-08	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.67	1.71e-07	GO:0034645	cellular macromolecule biosynthetic process
1.65	4.21e-07	GO:0009059	macromolecule biosynthetic process
1.81	4.31e-07	GO:0044248	cellular catabolic process
2.28	5.82e-07	GO:0006753	nucleoside phosphate metabolic process
2.28	5.82e-07	GO:0009117	nucleotide metabolic process
1.75	9.38e-07	GO:0051641	cellular localization
2.52	9.79e-07	GO:0044419	interspecies interaction between organisms
1.69	1.12e-06	GO:0009056	catabolic process
2.07	1.56e-06	GO:0046483	heterocycle metabolic process
2.14	1.60e-06	GO:0006259	DNA metabolic process
1.41	1.84e-06	GO:0016043	cellular component organization
1.79	2.53e-06	GO:0051649	establishment of localization in cell
2.18	4.17e-06	GO:0044265	cellular macromolecule catabolic process
1.70	4.93e-06	GO:0033036	macromolecule localization
2.16	6.39e-06	GO:0016071	mRNA metabolic process
2.98	7.88e-06	GO:0000375	RNA splicing, via transesterification reactions
1.45	9.63e-06	GO:0071842	cellular component organization at cellular level
1.60	1.08e-05	GO:0006996	organelle organization
2.05	1.09e-05	GO:0009057	macromolecule catabolic process
2.31	1.27e-05	GO:0016032	viral reproduction
3.21	1.48e-05	GO:0022415	viral reproductive process
1.71	2.16e-05	GO:0044085	cellular component biogenesis
2.17	2.18e-05	GO:0034621	cellular macromolecular complex subunit organization
3.38	2.38e-05	GO:0019058	viral infectious cycle
1.40	3.06e-05	GO:0019538	protein metabolic process
2.02	5.47e-05	GO:0071822	protein complex subunit organization
2.92	5.50e-05	GO:0022411	cellular component disassembly
2.92	5.50e-05	GO:0071845	cellular component disassembly at cellular level
3.74	6.70e-05	GO:0006414	translational elongation
2.27	7.78e-05	GO:0006397	mRNA processing
1.82	9.39e-05	GO:0033554	cellular response to stress
2.20	9.77e-05	GO:0072521	purine-containing compound metabolic process
2.27	1.45e-04	GO:0044271	cellular nitrogen compound biosynthetic process
2.80	1.64e-04	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.80	1.64e-04	GO:0000398	nuclear mRNA splicing, via spliceosome
2.06	2.41e-04	GO:0044283	small molecule biosynthetic process
1.79	2.56e-04	GO:0043933	macromolecular complex subunit organization
1.69	2.74e-04	GO:0008104	protein localization
2.77	3.22e-04	GO:0034404	nucleobase, nucleoside and nucleotide biosynthetic process
2.77	3.22e-04	GO:0034654	nucleobase, nucleoside, nucleotide and nucleic acid biosynthetic process
3.43	3.79e-04	GO:0032984	macromolecular complex disassembly
3.43	3.79e-04	GO:0034623	cellular macromolecular complex disassembly
2.36	4.50e-04	GO:0008380	RNA splicing
2.27	5.06e-04	GO:0006520	cellular amino acid metabolic process
2.58	5.11e-04	GO:0051186	cofactor metabolic process
1.76	6.00e-04	GO:0015031	protein transport
2.28	6.30e-04	GO:0009259	ribonucleotide metabolic process
1.75	6.67e-04	GO:0045184	establishment of protein localization
3.16	1.00e-03	GO:0042254	ribosome biogenesis
2.48	1.40e-03	GO:0018130	heterocycle biosynthetic process
2.75	1.45e-03	GO:0006732	coenzyme metabolic process
2.08	1.63e-03	GO:0044106	cellular amine metabolic process
1.35	1.91e-03	GO:0006810	transport
3.11	2.39e-03	GO:0050657	nucleic acid transport
3.11	2.39e-03	GO:0050658	RNA transport
3.11	2.39e-03	GO:0051236	establishment of RNA localization
2.69	2.40e-03	GO:0051169	nuclear transport
2.59	2.41e-03	GO:0006457	protein folding
5.85	2.46e-03	GO:0015682	ferric iron transport
5.85	2.46e-03	GO:0033572	transferrin transport
1.34	2.66e-03	GO:0051234	establishment of localization
2.91	2.98e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
3.25	3.27e-03	GO:0009260	ribonucleotide biosynthetic process
3.36	3.42e-03	GO:0043241	protein complex disassembly
3.36	3.42e-03	GO:0043624	cellular protein complex disassembly
2.31	3.82e-03	GO:0034660	ncRNA metabolic process
3.01	4.39e-03	GO:0006403	RNA localization
6.13	4.60e-03	GO:0009156	ribonucleoside monophosphate biosynthetic process
2.28	5.56e-03	GO:0010608	posttranscriptional regulation of gene expression
2.63	5.91e-03	GO:0006913	nucleocytoplasmic transport
1.29	6.94e-03	GO:0051179	localization
1.90	7.19e-03	GO:0006974	response to DNA damage stimulus
3.10	7.29e-03	GO:0051028	mRNA transport
2.08	7.54e-03	GO:0030163	protein catabolic process
2.04	7.59e-03	GO:0006163	purine nucleotide metabolic process
1.65	7.63e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.66	7.80e-03	GO:0051704	multi-organism process
2.81	8.92e-03	GO:0072522	purine-containing compound biosynthetic process
2.68	9.47e-03	GO:0043623	cellular protein complex assembly
4.14	9.90e-03	GO:0009112	nucleobase metabolic process
5.16	1.02e-02	GO:0006144	purine base metabolic process
1.59	1.32e-02	GO:0007049	cell cycle
1.88	1.38e-02	GO:0009308	amine metabolic process
5.50	1.46e-02	GO:0009161	ribonucleoside monophosphate metabolic process
2.08	1.75e-02	GO:0044257	cellular protein catabolic process
5.32	2.07e-02	GO:0015988	energy coupled proton transport, against electrochemical gradient
5.32	2.07e-02	GO:0015991	ATP hydrolysis coupled proton transport
2.09	2.36e-02	GO:0009150	purine ribonucleotide metabolic process
2.07	2.38e-02	GO:0071495	cellular response to endogenous stimulus
2.54	2.43e-02	GO:0009165	nucleotide biosynthetic process
2.07	2.57e-02	GO:0051603	proteolysis involved in cellular protein catabolic process
3.31	2.58e-02	GO:0009116	nucleoside metabolic process
2.46	3.09e-02	GO:0006260	DNA replication
2.52	4.12e-02	GO:0006417	regulation of translation
3.31	4.51e-02	GO:0006839	mitochondrial transport
1.55	4.53e-02	GO:0022607	cellular component assembly
1.56	4.79e-02	GO:0009892	negative regulation of metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.29	2.14e-39	GO:0044424	intracellular part
1.26	3.53e-36	GO:0005622	intracellular
1.39	2.02e-31	GO:0005737	cytoplasm
1.57	2.16e-31	GO:0044446	intracellular organelle part
2.04	3.46e-31	GO:0031974	membrane-enclosed lumen
1.55	1.24e-30	GO:0044422	organelle part
2.02	4.11e-29	GO:0043233	organelle lumen
2.03	6.06e-29	GO:0070013	intracellular organelle lumen
2.01	8.17e-27	GO:0044428	nuclear part
1.34	3.00e-26	GO:0043227	membrane-bounded organelle
1.33	4.17e-26	GO:0043231	intracellular membrane-bounded organelle
1.29	6.06e-25	GO:0043226	organelle
1.29	6.33e-25	GO:0043229	intracellular organelle
2.03	6.65e-23	GO:0031981	nuclear lumen
1.43	1.47e-20	GO:0044444	cytoplasmic part
1.43	2.91e-18	GO:0005634	nucleus
2.84	4.64e-16	GO:0005730	nucleolus
1.56	5.93e-16	GO:0032991	macromolecular complex
2.03	1.59e-15	GO:0005654	nucleoplasm
1.76	1.31e-14	GO:0005829	cytosol
2.61	7.11e-13	GO:0030529	ribonucleoprotein complex
2.22	8.97e-11	GO:0031967	organelle envelope
2.18	2.58e-10	GO:0031975	envelope
1.48	4.45e-08	GO:0043228	non-membrane-bounded organelle
1.48	4.45e-08	GO:0043232	intracellular non-membrane-bounded organelle
1.45	5.06e-08	GO:0043234	protein complex
9.75	4.76e-07	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.68	6.60e-07	GO:0005739	mitochondrion
2.01	6.79e-07	GO:0044429	mitochondrial part
1.07	8.09e-07	GO:0044464	cell part
1.07	8.36e-07	GO:0005623	cell
2.21	1.65e-06	GO:0005740	mitochondrial envelope
2.20	5.05e-06	GO:0031966	mitochondrial membrane
1.91	5.77e-06	GO:0044451	nucleoplasm part
2.36	1.04e-05	GO:0019866	organelle inner membrane
2.30	1.07e-04	GO:0005743	mitochondrial inner membrane
2.55	1.19e-04	GO:0016604	nuclear body
7.18	5.19e-04	GO:0033176	proton-transporting V-type ATPase complex
1.40	7.52e-04	GO:0031090	organelle membrane
3.41	8.25e-04	GO:0042470	melanosome
3.41	8.25e-04	GO:0048770	pigment granule
4.45	3.48e-03	GO:0016469	proton-transporting two-sector ATPase complex
8.70	8.41e-03	GO:0005744	mitochondrial inner membrane presequence translocase complex
2.17	1.16e-02	GO:0005635	nuclear envelope
2.62	1.20e-02	GO:0005681	spliceosomal complex
1.71	2.63e-02	GO:0005694	chromosome
8.86	3.90e-02	GO:0016281	eukaryotic translation initiation factor 4F complex
8.86	3.90e-02	GO:0033180	proton-transporting V-type ATPase, V1 domain

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.47	1.49e-34	GO:0005515	protein binding
2.36	1.70e-15	GO:0003723	RNA binding
1.17	2.80e-15	GO:0005488	binding
3.74	2.68e-04	GO:0008135	translation factor activity, nucleic acid binding
1.40	2.87e-04	GO:0000166	nucleotide binding
1.31	5.43e-04	GO:0003676	nucleic acid binding
1.92	2.24e-03	GO:0016874	ligase activity
5.70	2.52e-03	GO:0003727	single-stranded RNA binding
7.09	3.48e-03	GO:0046961	proton-transporting ATPase activity, rotational mechanism
1.20	5.28e-03	GO:0003824	catalytic activity
2.09	7.98e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
6.38	8.95e-03	GO:0003746	translation elongation factor activity
4.78	3.76e-02	GO:0019829	cation-transporting ATPase activity
3.11	4.47e-02	GO:0003729	mRNA binding