Motif ID: ATF6.p2

Z-value: 2.012


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF6chr1_+_1617361090.309.2e-06Click!


Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_94024201 40.223 COL1A2
collagen, type I, alpha 2
chr7_+_94023872 28.277 NM_000089
 COL1A2
collagen, type I, alpha 2
chrX_+_47441802 24.019 TIMP1
TIMP metallopeptidase inhibitor 1
chr17_-_46688279 23.157 HOXB7
homeobox B7
chrX_+_47441650 21.055 NM_003254
 TIMP1
TIMP metallopeptidase inhibitor 1
chr7_+_64498643 20.937 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr13_+_113951537 20.458 LAMP1
lysosomal-associated membrane protein 1
chr5_-_172198160 20.134 NM_004417
 DUSP1
dual specificity phosphatase 1
chr3_+_100211554 19.667 TMEM45A
transmembrane protein 45A
chr3_+_100211408 19.651 NM_018004
 TMEM45A
transmembrane protein 45A
chr2_+_28615695 19.592 FOSL2
FOS-like antigen 2
chr6_+_7590405 19.549 NM_152551
 SNRNP48
small nuclear ribonucleoprotein 48kDa (U11/U12)
chr20_-_39766522 19.535


chr9_+_74526527 18.630 C9orf85
chromosome 9 open reading frame 85
chr6_-_108145507 18.009 NM_198081
 SCML4
sex comb on midleg-like 4 (Drosophila)
chr7_-_6523689 17.887 NM_001100603
NM_006854
 KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr16_+_69796237 17.700 NM_007014
NM_199423
 WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr13_+_45915479 17.245 LOC100190939
uncharacterized LOC100190939
chr5_-_133706717 16.635 CDKL3
cyclin-dependent kinase-like 3
chr2_-_216300770 16.162 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1






Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 109 entries
enrichment   p-value GO term description
6.64 2.81e-02 GO:0048199 vesicle targeting, to, from or within Golgi
4.37 2.36e-03 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
3.95 9.30e-03 GO:0034138 toll-like receptor 3 signaling pathway
3.87 2.97e-03 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
3.85 6.46e-03 GO:0034130 toll-like receptor 1 signaling pathway
3.85 6.46e-03 GO:0034134 toll-like receptor 2 signaling pathway
3.83 1.41e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
3.50 2.45e-02 GO:0008063 Toll signaling pathway
3.50 2.45e-02 GO:0034142 toll-like receptor 4 signaling pathway
3.32 2.70e-02 GO:0002224 toll-like receptor signaling pathway
3.02 2.77e-03 GO:0016055 Wnt receptor signaling pathway
2.91 1.29e-03 GO:0009952 anterior/posterior pattern formation
2.68 2.48e-02 GO:0048562 embryonic organ morphogenesis
2.53 2.19e-05 GO:0001501 skeletal system development
2.36 1.00e-02 GO:0000165 MAPKKK cascade
2.36 3.82e-02 GO:0048514 blood vessel morphogenesis
2.29 5.49e-03 GO:0001944 vasculature development
2.27 1.51e-12 GO:0006351 transcription, DNA-dependent
2.27 1.79e-02 GO:0001568 blood vessel development
2.18 4.18e-02 GO:0035295 tube development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
3.76 2.11e-02 GO:0005793 ER-Golgi intermediate compartment
3.02 8.51e-03 GO:0005788 endoplasmic reticulum lumen
2.99 2.74e-02 GO:0042470 melanosome
2.99 2.74e-02 GO:0048770 pigment granule
1.83 1.06e-02 GO:0000139 Golgi membrane
1.80 2.91e-03 GO:0044431 Golgi apparatus part
1.68 6.86e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.67 6.91e-03 GO:0031988 membrane-bounded vesicle
1.65 5.02e-04 GO:0005794 Golgi apparatus
1.62 1.50e-02 GO:0031410 cytoplasmic vesicle
1.61 2.55e-02 GO:0044432 endoplasmic reticulum part
1.60 9.93e-04 GO:0005783 endoplasmic reticulum
1.59 2.40e-02 GO:0031982 vesicle
1.46 1.59e-02 GO:0005654 nucleoplasm
1.45 3.67e-03 GO:0012505 endomembrane system
1.39 1.13e-02 GO:0031981 nuclear lumen
1.37 2.78e-03 GO:0043233 organelle lumen
1.36 3.29e-03 GO:0031974 membrane-enclosed lumen
1.35 9.53e-03 GO:0070013 intracellular organelle lumen
1.34 2.42e-02 GO:0031090 organelle membrane

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
4.23 4.13e-03 GO:0003707 steroid hormone receptor activity
4.00 8.12e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.38 7.12e-03 GO:0000975 regulatory region DNA binding
2.38 7.12e-03 GO:0001067 regulatory region nucleic acid binding
2.38 7.12e-03 GO:0044212 transcription regulatory region DNA binding
2.35 1.01e-11 GO:0043565 sequence-specific DNA binding
2.25 1.81e-15 GO:0001071 nucleic acid binding transcription factor activity
2.25 1.81e-15 GO:0003700 sequence-specific DNA binding transcription factor activity
2.23 7.02e-05 GO:0000988 protein binding transcription factor activity
2.23 7.02e-05 GO:0000989 transcription factor binding transcription factor activity
2.19 1.62e-04 GO:0003712 transcription cofactor activity
2.03 3.16e-02 GO:0008134 transcription factor binding
1.90 3.01e-08 GO:0030528 transcription regulator activity
1.46 1.25e-05 GO:0003677 DNA binding
1.28 1.26e-10 GO:0005515 protein binding
1.26 4.92e-02 GO:0003676 nucleic acid binding
1.13 6.31e-07 GO:0005488 binding