Motif ID: AUGACAC

Z-value: 0.483


Mature miRNA associated with seed AUGACAC:

NamemiRBase Accession
hsa-miR-425 MIMAT0003393



Activity profile for motif AUGACAC.

activity profile for motif AUGACAC


Sorted Z-values histogram for motif AUGACAC

Sorted Z-values for motif AUGACAC



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGACAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_141521365 4.490 NM_017444
CHRAC1
chromatin accessibility complex 1
chr1_+_151254740 3.751 NM_020832
ZNF687
zinc finger protein 687
chr4_+_187112635 3.494 NM_207352
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr2_+_203499819 3.317 NM_173511
FAM117B
family with sequence similarity 117, member B
chr11_-_102962903 3.033 NM_032299
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5 (S. cerevisiae)
chrX_-_103401607 2.819 NM_001012755
MCART6
mitochondrial carrier triple repeat 6
chr14_+_92790151 2.796 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr20_+_10199455 2.708 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr2_+_17935379 2.686 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr2_+_17935124 2.640 NM_182625
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr5_-_79286793 2.496 NM_001010891
NM_001167741
MTX3

metaxin 3

chr14_+_92789536 2.483 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr1_-_11866079 2.468 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_+_38420690 2.398 NM_004615
TSPAN7
tetraspanin 7
chr7_+_45614081 2.342 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr19_+_32896515 2.081 NM_001172774
DPY19L3
dpy-19-like 3 (C. elegans)
chr14_+_92788924 2.064 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_42917632 1.931 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr10_+_105036783 1.869 NM_032727
INA
internexin neuronal intermediate filament protein, alpha
chr11_-_12030882 1.806 NM_013253
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_163038395 1.798 NM_001102445
RGS4
regulator of G-protein signaling 4
chr11_-_12030622 1.694 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr1_+_163041694 1.628 NM_001113380
RGS4
regulator of G-protein signaling 4
chr1_+_163038934 1.623 NM_001113381
RGS4
regulator of G-protein signaling 4
chr1_-_85725315 1.595 NM_198077
C1orf52
chromosome 1 open reading frame 52
chr8_-_26371387 1.578 NM_007257
PNMA2
paraneoplastic antigen MA2
chr1_+_163038564 1.544 NM_005613
RGS4
regulator of G-protein signaling 4
chr8_+_104152876 1.512 NM_001024372
NM_024812
BAALC

brain and acute leukemia, cytoplasmic

chr5_-_74162614 1.493 NM_015566
FAM169A
family with sequence similarity 169, member A
chr11_-_12030128 1.467 NM_001018057
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr22_-_44708730 1.453 NM_001099294
KIAA1644
KIAA1644
chrX_-_140271293 1.450 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr2_-_176866925 1.386 NM_030650
KIAA1715
KIAA1715
chr1_+_44412418 1.382 NM_014652
IPO13
importin 13
chr16_+_29674568 1.377 NM_003123
SPN
sialophorin
chr12_-_6798619 1.353 NM_001039920
NM_001135734
ZNF384

zinc finger protein 384

chr14_-_53620032 1.313 NM_001160147
NM_001160148
NM_030637
DDHD1


DDHD domain containing 1


chr12_-_6798528 1.278 NM_133476
ZNF384
zinc finger protein 384
chr16_+_1664640 1.264 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr10_-_79789290 1.263 NM_007055
POLR3A
polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr5_-_146889618 1.262 NM_001197294
DPYSL3
dihydropyrimidinase-like 3
chr13_-_46626845 1.257 NM_015070
ZC3H13
zinc finger CCCH-type containing 13
chr11_-_18655962 1.232 NM_194285
SPTY2D1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr17_-_18585571 1.232 NM_001145045
ZNF286B
zinc finger protein 286B
chr1_+_153388999 1.230 NM_176823
S100A7A
S100 calcium binding protein A7A
chr12_-_104234968 1.221 NM_001031701
NT5DC3
5'-nucleotidase domain containing 3
chr1_+_226736500 1.180 NM_001003665
C1orf95
chromosome 1 open reading frame 95
chr12_-_112450914 1.173 NM_001193453
NM_001193531
NM_138341
LOC728543
TMEM116


uncharacterized LOC728543
transmembrane protein 116


chr3_+_150264514 1.171 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr3_+_15469052 1.149 NM_033083
EAF1
ELL associated factor 1
chr16_+_29674282 1.141 NM_001030288
SPN
sialophorin
chrX_-_67653169 1.115 NM_002547
OPHN1
oligophrenin 1
chr4_-_39640461 1.113 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr12_+_32654976 1.110 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_+_15573767 1.080 NM_052929
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr8_-_27630096 1.071 NM_018246
CCDC25
coiled-coil domain containing 25
chr11_-_133402227 1.070 NM_001012393
OPCML
opioid binding protein/cell adhesion molecule-like
chr17_+_27055797 1.022 NM_178170
NEK8
NIMA (never in mitosis gene a)- related kinase 8
chr14_-_53258329 1.017 NM_198066
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr3_+_36421944 1.014 NM_003149
STAC
SH3 and cysteine rich domain
chr11_-_123525300 0.989 NM_001040151
NM_018400
SCN3B

sodium channel, voltage-gated, type III, beta

chr4_-_7941092 0.988 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr22_-_28197469 0.986 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr3_+_122283139 0.981 NM_138287
DTX3L
deltex 3-like (Drosophila)
chr1_-_54665670 0.978 NM_001031672
CYB5RL
cytochrome b5 reductase-like
chr9_+_100263461 0.972 NM_001166116
TMOD1
tropomodulin 1
chr9_+_100263818 0.969 NM_003275
TMOD1
tropomodulin 1
chr22_+_26565424 0.959 NM_001184773
NM_001184774
NM_001184775
NM_001184776
NM_001184777
NM_021115
SEZ6L





seizure related 6 homolog (mouse)-like





chr7_-_135194823 0.956 NM_001008225
NM_001190847
NM_001190848
NM_001190849
NM_001190850
NM_013316
CNOT4





CCR4-NOT transcription complex, subunit 4





chr13_-_95364248 0.953 NM_007084
SOX21
SRY (sex determining region Y)-box 21
chr6_-_36355342 0.951 NM_001207038
NM_001207035
NM_001207036
NM_001207037
NM_001207039
NM_001207040
NM_001207041
NM_016135
ETV7







ets variant 7







chr11_-_118661898 0.941 NM_004397
DDX6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
chr11_+_74699939 0.937 NM_006656
NEU3
sialidase 3 (membrane sialidase)
chr16_+_8768403 0.929 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr11_+_120894756 0.927 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr11_-_207403 0.916 NM_001098787
NM_016526
BET1L

blocked early in transport 1 homolog (S. cerevisiae)-like

chr11_-_132812870 0.911 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr13_-_22033505 0.910 NM_153251
ZDHHC20
zinc finger, DHHC-type containing 20
chr6_-_91006460 0.901 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr4_-_120548329 0.891 NM_033430
PDE5A
phosphodiesterase 5A, cGMP-specific
chr1_-_202896368 0.890 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr5_-_172756505 0.889 NM_003714
STC2
stanniocalcin 2
chr10_-_50970321 0.885 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr19_+_18794391 0.877 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr15_-_51630735 0.877 NM_000103
NM_031226
CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

chr12_-_3982394 0.871 NM_020367
PARP11
poly (ADP-ribose) polymerase family, member 11
chr3_-_179169330 0.869 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr14_-_45431121 0.867 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr10_-_105614952 0.866 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr20_+_34042908 0.865 NM_007186
CEP250
centrosomal protein 250kDa
chr1_+_35225341 0.851 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr22_+_50247480 0.841 NM_014838
ZBED4
zinc finger, BED-type containing 4
chr19_-_46974789 0.836 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr15_-_64648359 0.832 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr8_-_41166931 0.832 NM_003012
SFRP1
secreted frizzled-related protein 1
chr19_+_7953380 0.831 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr6_-_91006580 0.831 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr11_+_12695851 0.830 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr7_+_87257704 0.826 NM_001134405
NM_001134406
NM_138290
RUNDC3B


RUN domain containing 3B


chr17_+_61554420 0.825 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr1_-_62785067 0.825 NM_181712
KANK4
KN motif and ankyrin repeat domains 4
chr5_-_138775213 0.819 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr4_-_156298094 0.818 NM_001039580
MAP9
microtubule-associated protein 9
chr12_-_53207843 0.817 NM_002272
KRT4
keratin 4
chr8_-_17658385 0.817 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr9_+_132934685 0.814 NM_014286
NCS1
neuronal calcium sensor 1
chr1_-_155532322 0.807 NM_018489
ASH1L
ash1 (absent, small, or homeotic)-like (Drosophila)
chr4_+_74702272 0.797 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr8_+_42010463 0.796 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr6_+_72922513 0.787 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr15_+_51200864 0.780 NM_001252127
NM_007347
AP4E1

adaptor-related protein complex 4, epsilon 1 subunit

chr5_+_177540465 0.774 NM_015111
N4BP3
NEDD4 binding protein 3
chr4_-_170947428 0.774 NM_021647
MFAP3L
microfibrillar-associated protein 3-like
chr13_+_24734788 0.770 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr17_-_28257017 0.770 NM_033389
SSH2
slingshot homolog 2 (Drosophila)
chr15_-_73661604 0.765 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr16_-_68002455 0.763 NM_001145961
NM_001145962
NM_005072
SLC12A4


solute carrier family 12 (potassium/chloride transporters), member 4


chr18_+_55102777 0.757 NM_004852
ONECUT2
one cut homeobox 2
chr7_-_44924946 0.757 NM_033224
PURB
purine-rich element binding protein B
chr21_-_40685697 0.757 NM_001007246
NM_018963
NM_033656
BRWD1


bromodomain and WD repeat domain containing 1


chr6_-_24645955 0.752 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr3_-_184971815 0.751 NM_001166415
NM_001966
EHHADH

enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase

chr17_+_45772629 0.746 NM_014726
TBKBP1
TBK1 binding protein 1
chr22_-_39240016 0.746 NM_014293
NPTXR
neuronal pentraxin receptor
chr8_+_26371461 0.743 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr4_+_123844210 0.742 NM_145207
SPATA5
spermatogenesis associated 5
chr12_+_53817638 0.737 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr13_-_37494370 0.733 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr1_-_184006828 0.731 NM_015101
GLT25D2
glycosyltransferase 25 domain containing 2
chr11_-_35547144 0.728 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr16_+_18995255 0.727 NM_024847
TMC7
transmembrane channel-like 7
chr3_+_38388222 0.726 NM_005108
XYLB
xylulokinase homolog (H. influenzae)
chrX_-_8700170 0.719 NM_000216
KAL1
Kallmann syndrome 1 sequence
chr1_+_118472364 0.712 NM_006784
WDR3
WD repeat domain 3
chr4_+_88742549 0.709 NM_001184694
MEPE
matrix extracellular phosphoglycoprotein
chr16_+_5008317 0.702 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr7_+_154862545 0.701 NM_024012
HTR5A
5-hydroxytryptamine (serotonin) receptor 5A
chr16_+_58549382 0.700 NM_001160305
NM_024860
SETD6

SET domain containing 6

chrX_-_6145887 0.700 NM_020742
NLGN4X
neuroligin 4, X-linked
chr5_-_146833150 0.693 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr12_+_122459791 0.693 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr5_-_154230212 0.689 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr13_+_32889594 0.689 NM_000059
BRCA2
breast cancer 2, early onset
chr4_+_88754120 0.686 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr11_-_9025531 0.683 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr1_-_171711093 0.682 NM_001185127
NM_003762
VAMP4

vesicle-associated membrane protein 4

chrX_+_77166178 0.682 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr14_+_103995473 0.682 NM_152307
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr4_-_56412968 0.681 NM_004898
CLOCK
clock homolog (mouse)
chr4_-_120549115 0.677 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr6_-_89927495 0.676 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr11_+_33563772 0.672 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr16_-_67997948 0.670 NM_001145963
SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr4_-_76439582 0.669 NM_001008925
NM_001009922
NM_015436
RCHY1


ring finger and CHY zinc finger domain containing 1


chr2_-_232395108 0.666 NM_006056
NMUR1
neuromedin U receptor 1
chr21_-_47648715 0.666 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr3_-_145968958 0.662 NM_001128306
NM_001177304
NM_020353
PLSCR4


phospholipid scramblase 4


chr21_-_33765149 0.661 NM_014825
URB1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr3_+_139654001 0.657 NM_022131
CLSTN2
calsyntenin 2
chr1_+_28099682 0.654 NM_177424
STX12
syntaxin 12
chr19_-_3606801 0.653 NM_001060
NM_201636
TBXA2R

thromboxane A2 receptor

chr15_-_50978983 0.652 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr4_-_90759446 0.646 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_3500620 0.643 NM_031304
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr17_+_47653176 0.639 NM_007225
NXPH3
neurexophilin 3
chr15_+_41952572 0.630 NM_001080541
NM_001164273
MGA

MAX gene associated

chr11_+_71709951 0.628 NM_001039659
NM_001039660
NM_173044
NM_005699
NM_173042
IL18BP




interleukin 18 binding protein




chr12_+_133613877 0.627 NM_003428
NM_001127372
ZNF84

zinc finger protein 84

chr1_-_26232643 0.626 NM_203401
STMN1
stathmin 1
chr10_+_121652084 0.626 NM_007190
SEC23IP
SEC23 interacting protein
chr5_-_34043234 0.624 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr17_+_53342320 0.622 NM_002126
HLF
hepatic leukemia factor
chr13_+_43148182 0.618 NM_003701
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr19_+_3506264 0.615 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr12_+_49372235 0.614 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chrX_+_43515406 0.613 NM_000240
MAOA
monoamine oxidase A
chr16_+_23765947 0.611 NM_022097
CHP2
calcineurin B homologous protein 2
chr7_+_79764087 0.608 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr16_-_53737713 0.605 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr8_+_79578258 0.602 NM_016010
FAM164A
family with sequence similarity 164, member A
chr16_+_8806825 0.600 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr3_-_160822625 0.598 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr1_-_11907741 0.597 NM_006172
NPPA
natriuretic peptide A
chr15_+_59063389 0.595 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr3_+_39851028 0.592 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr2_-_206950895 0.592 NM_017759
INO80D
INO80 complex subunit D
chr9_-_80646150 0.589 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr3_-_185826748 0.583 NM_004454
ETV5
ets variant 5
chr8_+_26435339 0.582 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr7_+_128828712 0.579 NM_005631
SMO
smoothened, frizzled family receptor
chr20_+_8112762 0.579 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr10_-_13342063 0.577 NM_006214
PHYH
phytanoyl-CoA 2-hydroxylase
chr19_-_3500937 0.576 NM_001145165
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr4_-_53525316 0.573 NM_022832
USP46
ubiquitin specific peptidase 46
chr6_+_72596648 0.572 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr2_-_213403280 0.569 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr12_-_51477299 0.567 NM_030809
CSRNP2
cysteine-serine-rich nuclear protein 2
chr16_+_50186809 0.567 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr4_+_37455551 0.566 NM_001104629
C4orf19
chromosome 4 open reading frame 19
chr1_-_160990971 0.565 NM_016946
F11R
F11 receptor

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 9.20e-04 GO:0016020 membrane
1.27 9.74e-03 GO:0044425 membrane part
1.50 3.34e-02 GO:0044459 plasma membrane part
2.48 3.43e-02 GO:0005815 microtubule organizing center

Gene overrepresentation in function category:

enrichment   p-value GO term description
13.93 4.88e-02 GO:0048185 activin binding