Motif ID: AUGGCUU

Z-value: 1.272


Mature miRNA associated with seed AUGGCUU:

NamemiRBase Accession
hsa-miR-135a MIMAT0000428
hsa-miR-135b MIMAT0000758



Activity profile for motif AUGGCUU.

activity profile for motif AUGGCUU


Sorted Z-values histogram for motif AUGGCUU

Sorted Z-values for motif AUGGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCUU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_24771268 37.941 NM_005382
 NEFM
neurofilament, medium polypeptide
chr8_+_24772454 36.375 NM_001105541
 NEFM
neurofilament, medium polypeptide
chr16_+_58498725 31.169 NM_022910
 NDRG4
NDRG family member 4
chr16_+_58534045 30.678 NM_001242833
NM_001242834
NM_001242835
NM_001242836
 NDRG4



NDRG family member 4



chr16_+_58497993 28.213 NM_001130487
 NDRG4
NDRG family member 4
chr16_+_58497548 26.816 NM_020465
 NDRG4
NDRG family member 4
chr1_+_171810611 22.040 NM_001136127
NM_015569
 DNM3

dynamin 3

chr12_+_79257772 21.931 NM_001135805
 SYT1
synaptotagmin I
chr2_+_131674223 20.939 NM_015320
NM_032995
 ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr12_+_79439432 19.725 NM_001135806
 SYT1
synaptotagmin I
chr16_+_8768403 19.261 NM_020686
 ABAT
4-aminobutyrate aminotransferase
chr5_-_88179278 19.249 NM_001193350
NM_002397
 MEF2C

myocyte enhancer factor 2C

chr12_+_79258448 19.236 NM_005639
 SYT1
synaptotagmin I
chr9_-_93405066 18.958 NM_017594
 DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr3_+_49591897 18.394 NM_003458
 BSN
bassoon (presynaptic cytomatrix protein)
chr15_+_91643429 18.177 NM_014848
 SV2B
synaptic vesicle glycoprotein 2B
chr11_-_117186918 17.220 NM_012104
NM_138971
NM_138972
NM_138973
 BACE1



beta-site APP-cleaving enzyme 1



chr9_-_79520878 17.115 NM_015225
 PRUNE2
prune homolog 2 (Drosophila)
chr15_+_91643181 17.040 NM_001167580
 SV2B
synaptic vesicle glycoprotein 2B
chr8_-_27115897 16.854 NM_030795
 STMN4
stathmin-like 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
4.20 4.65e-05 GO:0048011 nerve growth factor receptor signaling pathway
2.90 1.18e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
2.88 3.09e-06 GO:0007167 enzyme linked receptor protein signaling pathway
2.83 1.15e-02 GO:0051056 regulation of small GTPase mediated signal transduction
2.79 1.26e-06 GO:0006468 protein phosphorylation
2.75 5.00e-03 GO:0007268 synaptic transmission
2.64 4.71e-03 GO:0019226 transmission of nerve impulse
2.64 4.71e-03 GO:0035637 multicellular organismal signaling
2.57 6.65e-06 GO:0016310 phosphorylation
2.57 1.74e-02 GO:0045859 regulation of protein kinase activity
2.53 1.94e-10 GO:0035556 intracellular signal transduction
2.46 3.55e-02 GO:0043549 regulation of kinase activity
2.41 5.21e-06 GO:0006793 phosphorus metabolic process
2.41 5.21e-06 GO:0006796 phosphate metabolic process
2.07 2.14e-05 GO:0007399 nervous system development
1.83 1.45e-02 GO:0009966 regulation of signal transduction
1.82 7.22e-04 GO:0006464 protein modification process
1.82 3.37e-03 GO:0023051 regulation of signaling
1.78 5.31e-10 GO:0023052 signaling
1.78 3.09e-03 GO:0007166 cell surface receptor linked signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
31.67 1.27e-02 GO:0042583 chromaffin granule
31.67 1.27e-02 GO:0042584 chromaffin granule membrane
14.08 3.25e-02 GO:0005942 phosphatidylinositol 3-kinase complex
4.75 1.20e-02 GO:0001726 ruffle
3.37 1.05e-04 GO:0044456 synapse part
3.36 2.02e-02 GO:0030424 axon
3.27 3.74e-06 GO:0045202 synapse
3.05 3.43e-02 GO:0034702 ion channel complex
2.76 1.33e-03 GO:0043005 neuron projection
2.53 1.90e-04 GO:0030054 cell junction
2.02 7.13e-03 GO:0042995 cell projection
1.66 8.97e-04 GO:0044459 plasma membrane part
1.23 5.19e-03 GO:0005737 cytoplasm
1.15 3.93e-03 GO:0005622 intracellular
1.15 1.57e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
3.45 3.47e-02 GO:0005085 guanyl-nucleotide exchange factor activity
3.26 4.23e-04 GO:0005083 small GTPase regulator activity
3.03 2.65e-05 GO:0004674 protein serine/threonine kinase activity
2.66 9.01e-04 GO:0030695 GTPase regulator activity
2.59 1.50e-03 GO:0060589 nucleoside-triphosphatase regulator activity
2.47 4.18e-04 GO:0004672 protein kinase activity
2.45 6.18e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.34 1.47e-04 GO:0016301 kinase activity
2.07 2.40e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.75 4.99e-03 GO:0032559 adenyl ribonucleotide binding
1.74 5.88e-03 GO:0030554 adenyl nucleotide binding
1.72 1.20e-02 GO:0005524 ATP binding
1.71 1.33e-03 GO:0032553 ribonucleotide binding
1.71 1.33e-03 GO:0032555 purine ribonucleotide binding
1.70 1.62e-03 GO:0017076 purine nucleotide binding
1.69 2.78e-03 GO:0035639 purine ribonucleoside triphosphate binding