Motif ID: AUGGCUU

Z-value: 1.272


Mature miRNA associated with seed AUGGCUU:

NamemiRBase Accession
hsa-miR-135a MIMAT0000428
hsa-miR-135b MIMAT0000758



Activity profile for motif AUGGCUU.

activity profile for motif AUGGCUU


Sorted Z-values histogram for motif AUGGCUU

Sorted Z-values for motif AUGGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AUGGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_24771268 37.941 NM_005382
NEFM
neurofilament, medium polypeptide
chr8_+_24772454 36.375 NM_001105541
NEFM
neurofilament, medium polypeptide
chr16_+_58498725 31.169 NM_022910
NDRG4
NDRG family member 4
chr16_+_58534045 30.678 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr16_+_58497993 28.213 NM_001130487
NDRG4
NDRG family member 4
chr16_+_58497548 26.816 NM_020465
NDRG4
NDRG family member 4
chr1_+_171810611 22.040 NM_001136127
NM_015569
DNM3

dynamin 3

chr12_+_79257772 21.931 NM_001135805
SYT1
synaptotagmin I
chr2_+_131674223 20.939 NM_015320
NM_032995
ARHGEF4

Rho guanine nucleotide exchange factor (GEF) 4

chr12_+_79439432 19.725 NM_001135806
SYT1
synaptotagmin I
chr16_+_8768403 19.261 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr5_-_88179278 19.249 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr12_+_79258448 19.236 NM_005639
SYT1
synaptotagmin I
chr9_-_93405066 18.958 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr3_+_49591897 18.394 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr15_+_91643429 18.177 NM_014848
SV2B
synaptic vesicle glycoprotein 2B
chr11_-_117186918 17.220 NM_012104
NM_138971
NM_138972
NM_138973
BACE1



beta-site APP-cleaving enzyme 1



chr9_-_79520878 17.115 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr15_+_91643181 17.040 NM_001167580
SV2B
synaptic vesicle glycoprotein 2B
chr8_-_27115897 16.854 NM_030795
STMN4
stathmin-like 4
chr17_+_40834571 16.310 NM_003632
CNTNAP1
contactin associated protein 1
chr17_-_10101854 16.197 NM_201433
GAS7
growth arrest-specific 7
chr5_-_136834887 15.952 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_+_121322848 15.642 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_-_38720312 15.550 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr17_-_9862765 15.059 NM_003644
GAS7
growth arrest-specific 7
chr11_-_117166247 14.447 NM_001207048
NM_001207049
BACE1

beta-site APP-cleaving enzyme 1

chr16_+_8806825 14.248 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr17_-_8066254 14.195 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr4_-_87028805 13.257 NM_138981
MAPK10
mitogen-activated protein kinase 10
chr17_-_78450247 13.182 NM_002522
NPTX1
neuronal pentraxin I
chr16_+_8814567 12.068 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr17_-_9929567 11.974 NM_001130831
GAS7
growth arrest-specific 7
chr7_+_45614081 11.851 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr19_-_17799005 11.762 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr5_-_88199868 11.320 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr20_-_32031425 11.195 NM_003098
SNTA1
syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
chr8_+_38034066 11.162 NM_001204878
NM_004874
BAG4

BCL2-associated athanogene 4

chr1_-_155948317 11.087 NM_001162383
NM_001162384
ARHGEF2

Rho/Rac guanine nucleotide exchange factor (GEF) 2

chr1_+_183605207 10.997 NM_015149
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr10_-_62149487 10.940 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_87374282 10.876 NM_002753
MAPK10
mitogen-activated protein kinase 10
chr18_+_32558207 10.768 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_-_155947898 10.735 NM_004723
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr10_-_62493282 10.413 NM_001204403
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr17_-_9940004 10.382 NM_201432
GAS7
growth arrest-specific 7
chr2_+_166150340 10.223 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr14_+_69865380 9.919 NM_001252148
NM_001252150
NM_018375
SLC39A9


solute carrier family 39 (zinc transporter), member 9


chr10_-_81205091 9.909 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr8_-_18871163 9.624 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr19_+_18263998 9.573 NM_005027
PIK3R2
phosphoinositide-3-kinase, regulatory subunit 2 (beta)
chr4_-_87281374 9.256 NM_138980
NM_138982
MAPK10

mitogen-activated protein kinase 10

chr6_+_138483024 9.178 NM_020340
KIAA1244
KIAA1244
chr3_-_10547267 9.138 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr1_-_202612580 9.089 NM_001136504
SYT2
synaptotagmin II
chr19_+_10541334 8.969 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_38714781 8.635 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr7_+_149535508 8.605 NM_001099220
ZNF862
zinc finger protein 862
chr1_-_202679415 8.415 NM_177402
SYT2
synaptotagmin II
chr17_-_66287256 8.248 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr18_+_32556891 8.235 NM_001143826
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr2_+_166152282 8.167 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_-_240322620 8.155 NM_006037
HDAC4
histone deacetylase 4
chr8_-_18666295 8.104 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr4_+_154074269 8.086 NM_001130067
TRIM2
tripartite motif containing 2
chr8_+_28747885 8.067 NM_001135726
HMBOX1
homeobox containing 1
chr4_+_154125589 8.038 NM_015271
TRIM2
tripartite motif containing 2
chr15_-_50978983 8.029 NM_017672
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr8_-_125740650 8.000 NM_014751
MTSS1
metastasis suppressor 1
chr2_+_74273449 7.905 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr5_+_112043188 7.825 NM_001127511
APC
adenomatous polyposis coli
chr10_-_91403630 7.794 NM_138316
NM_148978
PANK1

pantothenate kinase 1

chr4_+_4387982 7.786 NM_001040101
NM_014392
D4S234E

DNA segment on chromosome 4 (unique) 234 expressed sequence

chr9_-_10612722 7.672 NM_002839
PTPRD
protein tyrosine phosphatase, receptor type, D
chr14_-_45431121 7.663 NM_017658
KLHL28
kelch-like 28 (Drosophila)
chr10_-_62332666 7.638 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr19_+_40973049 7.618 NM_020971
SPTBN4
spectrin, beta, non-erythrocytic 4
chr11_-_1593149 7.527 NM_004420
DUSP8
dual specificity phosphatase 8
chr2_-_213403280 7.477 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr19_-_40324747 7.300 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr5_+_149380168 7.287 NM_014983
HMGXB3
HMG box domain containing 3
chr8_+_28748030 7.118 NM_024567
HMBOX1
homeobox containing 1
chr1_+_24882565 6.886 NM_001010980
C1orf130
chromosome 1 open reading frame 130
chr8_+_58906968 6.855 NM_147189
FAM110B
family with sequence similarity 110, member B
chr9_-_123476578 6.842 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr16_+_1664640 6.791 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr22_+_50247480 6.716 NM_014838
ZBED4
zinc finger, BED-type containing 4
chr3_+_138067444 6.629 NM_001085049
NM_001252093
MRAS

muscle RAS oncogene homolog

chr2_-_2334887 6.538 NM_015025
MYT1L
myelin transcription factor 1-like
chr14_+_56584854 6.468 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr6_-_150185370 6.453 NM_032832
LRP11
low density lipoprotein receptor-related protein 11
chr3_+_138066489 6.424 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr4_-_42658883 6.381 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr15_+_31619043 6.372 NM_015995
KLF13
Kruppel-like factor 13
chr13_+_35516390 6.251 NM_015678
NBEA
neurobeachin
chr5_+_112073555 6.139 NM_000038
NM_001127510
APC

adenomatous polyposis coli

chr7_+_152456820 6.126 NM_001040135
NM_020445
ACTR3B

ARP3 actin-related protein 3 homolog B (yeast)

chr1_+_209757044 6.059 NM_020439
CAMK1G
calcium/calmodulin-dependent protein kinase IG
chr1_+_159141376 5.951 NM_021189
NM_001127173
CADM3

cell adhesion molecule 3

chr6_+_72922513 5.925 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr10_-_61900659 5.911 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr8_+_94929082 5.858 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr2_-_11484699 5.850 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr1_+_169075869 5.830 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_+_53529030 5.817 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr19_-_12833461 5.804 NM_001136196
TNPO2
transportin 2
chr8_-_20112691 5.795 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr19_-_12832923 5.767 NM_013433
TNPO2
transportin 2
chr20_-_48532067 5.737 NM_006038
SPATA2
spermatogenesis associated 2
chr1_-_46598250 5.720 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr11_+_62475113 5.710 NM_012202
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chrX_-_47509993 5.703 NM_001114123
NM_005229
ELK1

ELK1, member of ETS oncogene family

chr10_+_112836784 5.583 NM_000681
ADRA2A
adrenergic, alpha-2A-, receptor
chr22_+_38004454 5.574 NM_001001560
NM_001001561
NM_001172687
NM_013365
GGA1



golgi-associated, gamma adaptin ear containing, ARF binding protein 1



chr5_-_114598547 5.574 NM_005023
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr14_+_99947732 5.545 NM_001099402
CCNK
cyclin K
chr17_-_7197866 5.491 NM_015982
YBX2
Y box binding protein 2
chr15_+_27111865 5.452 NM_000810
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr15_+_27112106 5.436 NM_001165037
GABRA5
gamma-aminobutyric acid (GABA) A receptor, alpha 5
chr3_+_123813527 5.424 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr4_+_140374960 5.347 NM_031296
RAB33B
RAB33B, member RAS oncogene family
chr19_+_10531128 5.271 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr13_+_98086315 5.243 NM_021033
RAP2A
RAP2A, member of RAS oncogene family
chr3_-_56502364 5.227 NM_015576
ERC2
ELKS/RAB6-interacting/CAST family member 2
chr7_+_4721722 5.214 NM_001037165
FOXK1
forkhead box K1
chr2_-_175547471 5.212 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr5_-_160975124 5.134 NM_000813
NM_021911
GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

chr5_+_76506705 5.089 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr15_-_33360084 4.956 NM_001103184
FMN1
formin 1
chr18_+_48556483 4.942 NM_005359
SMAD4
SMAD family member 4
chrX_-_107019001 4.904 NM_198057
TSC22D3
TSC22 domain family, member 3
chr10_+_116853118 4.798 NM_207303
ATRNL1
attractin-like 1
chr15_+_42066631 4.766 NM_001128608
NM_014994
MAPKBP1

mitogen-activated protein kinase binding protein 1

chr10_+_101419169 4.731 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr3_+_9691116 4.691 NM_001077525
NM_001077526
NM_022485
MTMR14


myotubularin related protein 14


chrX_-_106960268 4.652 NM_004089
TSC22D3
TSC22 domain family, member 3
chr1_+_53192021 4.610 NM_024646
ZYG11B
zyg-11 homolog B (C. elegans)
chr8_-_66753968 4.566 NM_001242318
PDE7A
phosphodiesterase 7A
chr20_+_42875905 4.561 NM_024034
GDAP1L1
ganglioside-induced differentiation-associated protein 1-like 1
chr17_-_28562953 4.547 NM_001045
SLC6A4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr12_-_58026846 4.512 NM_001478
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr22_-_42017032 4.434 NM_015704
PPPDE2
PPPDE peptidase domain containing 2
chr5_-_147162251 4.409 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr19_-_344778 4.350 NM_017550
MIER2
mesoderm induction early response 1, family member 2
chr11_+_13299260 4.318 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr13_-_41240607 4.239 NM_002015
FOXO1
forkhead box O1
chr11_-_85338313 4.223 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chr19_-_12834628 4.190 NM_001136195
TNPO2
transportin 2
chr12_+_58138663 4.155 NM_005981
TSPAN31
tetraspanin 31
chr2_+_7057471 4.085 NM_014746
RNF144A
ring finger protein 144A
chr6_+_17393610 4.080 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chrX_-_53310748 4.069 NM_001243197
NM_015075
IQSEC2

IQ motif and Sec7 domain 2

chr6_-_150039391 4.061 NM_004690
LATS1
LATS, large tumor suppressor, homolog 1 (Drosophila)
chr6_+_72926144 3.994 NM_001168409
RIMS1
regulating synaptic membrane exocytosis 1
chr18_+_32621299 3.985 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr18_-_29523087 3.968 NM_014939
TRAPPC8
trafficking protein particle complex 8
chr4_-_16900348 3.937 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr2_-_211341374 3.822 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr17_-_7832752 3.796 NM_004732
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr1_+_203595897 3.768 NM_001001396
NM_001684
ATP2B4

ATPase, Ca++ transporting, plasma membrane 4

chr10_+_86088156 3.753 NM_018999
FAM190B
family with sequence similarity 190, member B
chr12_+_4382882 3.751 NM_001759
CCND2
cyclin D2
chr8_+_104512975 3.718 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr19_+_10543110 3.717 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_27719151 3.715 NM_005281
GPR3
G protein-coupled receptor 3
chr2_-_201936389 3.708 NM_173822
FAM126B
family with sequence similarity 126, member B
chr17_-_62340652 3.697 NM_018469
TEX2
testis expressed 2
chr2_+_128848752 3.691 NM_020120
UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr2_+_166095911 3.687 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_+_142443214 3.663 NM_001251845
NM_003304
TRPC1

transient receptor potential cation channel, subfamily C, member 1

chrX_-_106959597 3.644 NM_001015881
TSC22D3
TSC22 domain family, member 3
chr1_-_184724021 3.614 NM_025191
EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr2_-_175351755 3.538 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chr16_+_639668 3.446 NM_001172664
RAB40C
RAB40C, member RAS oncogene family
chr19_-_2702738 3.444 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr6_+_73076431 3.391 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr12_+_64845839 3.387 NM_013254
TBK1
TANK-binding kinase 1
chr9_-_80646150 3.361 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr20_-_41818464 3.334 NM_007050
NM_133170
PTPRT

protein tyrosine phosphatase, receptor type, T

chr19_-_46295785 3.324 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr7_-_139876718 3.323 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr13_+_111806038 3.320 NM_003899
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr8_-_143695812 3.290 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr3_+_124303505 3.270 NM_007064
KALRN
kalirin, RhoGEF kinase
chr20_-_48099178 3.224 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr8_-_17658385 3.165 NM_001001924
NM_001001925
MTUS1

microtubule associated tumor suppressor 1

chr8_-_17579729 3.149 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr19_+_10563581 3.078 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_+_61699786 3.064 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr13_-_77460432 3.053 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr9_-_100395961 3.051 NM_139246
TSTD2
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr15_-_64648359 3.049 NM_022048
CSNK1G1
casein kinase 1, gamma 1
chr3_-_15106806 3.034 NM_022497
MRPS25
mitochondrial ribosomal protein S25
chr14_-_50698090 2.961 NM_006939
SOS2
son of sevenless homolog 2 (Drosophila)
chr9_-_139922705 2.916 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_205012329 2.912 NM_005076
CNTN2
contactin 2 (axonal)
chr3_+_43328001 2.895 NM_001100594
NM_017719
SNRK

SNF related kinase

chrX_+_122318095 2.895 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chrX_-_135863502 2.893 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_+_2328628 2.865 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.53 1.94e-10 GO:0035556 intracellular signal transduction
1.78 5.31e-10 GO:0023052 signaling
1.45 7.08e-09 GO:0050794 regulation of cellular process
1.74 1.12e-07 GO:0007165 signal transduction
1.38 1.41e-07 GO:0065007 biological regulation
1.38 9.88e-07 GO:0050789 regulation of biological process
2.79 1.26e-06 GO:0006468 protein phosphorylation
2.88 3.09e-06 GO:0007167 enzyme linked receptor protein signaling pathway
2.41 5.21e-06 GO:0006793 phosphorus metabolic process
2.41 5.21e-06 GO:0006796 phosphate metabolic process
2.57 6.65e-06 GO:0016310 phosphorylation
2.07 2.14e-05 GO:0007399 nervous system development
4.20 4.65e-05 GO:0048011 nerve growth factor receptor signaling pathway
2.90 1.18e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.51 2.11e-04 GO:0051716 cellular response to stimulus
1.20 3.15e-04 GO:0009987 cellular process
1.82 7.22e-04 GO:0006464 protein modification process
1.75 2.48e-03 GO:0043412 macromolecule modification
1.78 3.09e-03 GO:0007166 cell surface receptor linked signaling pathway
1.82 3.37e-03 GO:0023051 regulation of signaling
2.64 4.71e-03 GO:0019226 transmission of nerve impulse
2.64 4.71e-03 GO:0035637 multicellular organismal signaling
2.75 5.00e-03 GO:0007268 synaptic transmission
1.56 7.69e-03 GO:0048731 system development
1.52 8.29e-03 GO:0048856 anatomical structure development
2.83 1.15e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.83 1.45e-02 GO:0009966 regulation of signal transduction
2.57 1.74e-02 GO:0045859 regulation of protein kinase activity
1.64 2.19e-02 GO:0048869 cellular developmental process
1.64 2.97e-02 GO:0030154 cell differentiation
1.43 3.31e-02 GO:0032502 developmental process
2.46 3.55e-02 GO:0043549 regulation of kinase activity
1.45 4.72e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.27 3.74e-06 GO:0045202 synapse
3.37 1.05e-04 GO:0044456 synapse part
2.53 1.90e-04 GO:0030054 cell junction
1.66 8.97e-04 GO:0044459 plasma membrane part
2.76 1.33e-03 GO:0043005 neuron projection
1.15 3.93e-03 GO:0005622 intracellular
1.23 5.19e-03 GO:0005737 cytoplasm
2.02 7.13e-03 GO:0042995 cell projection
4.75 1.20e-02 GO:0001726 ruffle
31.67 1.27e-02 GO:0042583 chromaffin granule
31.67 1.27e-02 GO:0042584 chromaffin granule membrane
1.15 1.57e-02 GO:0044424 intracellular part
3.36 2.02e-02 GO:0030424 axon
14.08 3.25e-02 GO:0005942 phosphatidylinositol 3-kinase complex
3.05 3.43e-02 GO:0034702 ion channel complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.03 2.65e-05 GO:0004674 protein serine/threonine kinase activity
2.45 6.18e-05 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.34 1.47e-04 GO:0016301 kinase activity
2.47 4.18e-04 GO:0004672 protein kinase activity
3.26 4.23e-04 GO:0005083 small GTPase regulator activity
2.66 9.01e-04 GO:0030695 GTPase regulator activity
1.71 1.33e-03 GO:0032553 ribonucleotide binding
1.71 1.33e-03 GO:0032555 purine ribonucleotide binding
2.59 1.50e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.70 1.62e-03 GO:0017076 purine nucleotide binding
2.07 2.40e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.69 2.78e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.75 4.99e-03 GO:0032559 adenyl ribonucleotide binding
1.74 5.88e-03 GO:0030554 adenyl nucleotide binding
1.72 1.20e-02 GO:0005524 ATP binding
3.45 3.47e-02 GO:0005085 guanyl-nucleotide exchange factor activity