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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: BACH2.p2

Z-value: 2.053

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_223889253	129.570	NM_001146068	CAPN2	calpain 2, (m/II) large subunit
chr17_+_30771520	96.747		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_31704070	78.399		CLIC1	chloride intracellular channel 1
chr1_-_152009440	76.015		S100A11	S100 calcium binding protein A11
chr1_-_152009406	73.956		S100A11	S100 calcium binding protein A11
chr6_-_31704318	73.616	NM_001288	CLIC1	chloride intracellular channel 1
chr6_-_31704304	73.044		CLIC1	chloride intracellular channel 1
chr6_-_31704272	72.090		CLIC1	chloride intracellular channel 1
chr6_-_31704281	72.001		CLIC1	chloride intracellular channel 1
chr6_-_31704287	71.843		CLIC1	chloride intracellular channel 1
chr6_-_31704093	71.027		CLIC1	chloride intracellular channel 1
chr11_-_2950593	63.965	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr1_+_156084541	63.865		LMNA	lamin A/C
chr7_-_96339074	56.889		SHFM1	split hand/foot malformation (ectrodactyly) type 1
chr17_+_30771532	56.419		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr7_-_7758237	55.551	NM_002947	RPA3	replication protein A3, 14kDa
chr17_+_30771494	55.160	NM_002815	PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_30771485	54.503		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_30771522	51.242		PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_+_26606621	49.586		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr11_-_65667858	49.447		FOSL1	FOS-like antigen 1
chr1_+_156084565	49.162		LMNA	lamin A/C
chr3_+_183894736	48.266		AP2M1	adaptor-related protein complex 2, mu 1 subunit
chr1_+_223900226	48.123		CAPN2	calpain 2, (m/II) large subunit
chr15_+_22892683	47.425	NM_014608	CYFIP1	cytoplasmic FMR1 interacting protein 1
chr17_-_73150769	47.069	NM_001002032 NM_001002033 NM_016185	HN1	hematological and neurological expressed 1
chr1_+_26606586	46.629		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr11_-_65667809	46.415		FOSL1	FOS-like antigen 1
chr1_-_152009490	45.059	NM_005620	S100A11	S100 calcium binding protein A11
chr15_+_22892714	44.335		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr15_+_22892723	44.083		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr12_-_53343607	44.000		KRT8	keratin 8
chr1_-_109969058	42.957	NM_001199772 NM_002790 NM_001199773 NM_001199774	PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr20_-_52199635	42.837	NM_006526	ZNF217	zinc finger protein 217
chr1_+_223900061	42.796	NM_001748	CAPN2	calpain 2, (m/II) large subunit
chr2_-_85641128	42.203		CAPG	capping protein (actin filament), gelsolin-like
chr1_+_156084579	41.610		LMNA	lamin A/C
chr1_+_156084458	41.153	NM_005572 NM_170707 NM_170708	LMNA	lamin A/C
chr16_+_30077120	40.566		ALDOA	aldolase A, fructose-bisphosphate
chr16_+_30076993	40.440	NM_001243177 NM_184041	ALDOA	aldolase A, fructose-bisphosphate
chr15_+_22892517	40.199		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr15_-_60690115	40.096	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr8_+_26150731	39.603	NM_001177591	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr16_+_30077146	39.227		ALDOA	aldolase A, fructose-bisphosphate
chr1_-_225616556	38.681	NM_194442	LBR	lamin B receptor
chr19_+_36630846	38.203	NM_001003962 NM_001749	CAPNS1	calpain, small subunit 1
chr19_+_36630999	37.633		CAPNS1	calpain, small subunit 1
chr1_-_246580710	36.713	NM_022743	SMYD3	SET and MYND domain containing 3
chr19_+_36631001	35.698		CAPNS1	calpain, small subunit 1
chr1_-_109969044	35.579		PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr6_-_38670904	34.909		GLO1	glyoxalase I
chr6_-_38670915	34.895		GLO1	glyoxalase I
chr6_-_38670871	34.126		GLO1	glyoxalase I
chr6_-_38670922	33.873	NM_006708	GLO1	glyoxalase I
chr6_-_38670882	33.747		GLO1	glyoxalase I
chr6_-_38670829	32.575		GLO1	glyoxalase I
chr22_-_43343046	32.565	NM_007229	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr14_+_103801160	32.451	NM_183004	EIF5	eukaryotic translation initiation factor 5
chr5_+_73981055	32.019		HEXB	hexosaminidase B (beta polypeptide)
chr7_-_96339171	31.691	NM_006304	SHFM1	split hand/foot malformation (ectrodactyly) type 1
chr1_-_84972259	31.624	NM_005274	GNG5	guanine nucleotide binding protein (G protein), gamma 5
chr5_+_159436143	31.112		TTC1	tetratricopeptide repeat domain 1
chr11_+_67351065	31.110	NM_000852	GSTP1	glutathione S-transferase pi 1
chr6_+_44195008	30.921		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr15_+_22892699	29.446		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr5_+_138089073	29.309	NM_001903	CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr1_-_24126031	29.301	NM_001127621	GALE	UDP-galactose-4-epimerase
chr6_-_159239254	29.215		EZR	ezrin
chr12_-_76478347	29.160		NAP1L1	nucleosome assembly protein 1-like 1
chr17_+_30677178	28.835		ZNF207	zinc finger protein 207
chr5_+_72143993	28.807		TNPO1	transportin 1
chr14_-_23426356	28.745		HAUS4	HAUS augmin-like complex, subunit 4
chr3_-_49395697	28.120		GPX1	glutathione peroxidase 1
chr1_-_109968951	28.005		PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5
chr1_+_223900212	27.477		CAPN2	calpain 2, (m/II) large subunit
chr7_-_99006215	27.399		PDAP1	PDGFA associated protein 1
chr17_+_30677138	27.381	NM_001032293 NM_001098507 NM_003457	ZNF207	zinc finger protein 207
chr6_-_159239198	27.309		EZR	ezrin
chr6_-_159239269	27.134	NM_003379	EZR	ezrin
chr7_-_99006170	27.125		PDAP1	PDGFA associated protein 1
chr11_-_65667860	27.022	NM_005438	FOSL1	FOS-like antigen 1
chr1_-_209824641	26.942	NM_001017402	LAMB3	laminin, beta 3
chr17_+_18625335	26.903	NM_001037330	TRIM16L	tripartite motif containing 16-like
chr1_-_27816676	26.769	NM_001201404 NM_006990	WASF2	WAS protein family, member 2
chr5_+_138089118	26.759		CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chrX_-_15511710	26.404	NM_001018109 NM_003662	PIR	pirin (iron-binding nuclear protein)
chr5_+_72143929	26.348	NM_153188	TNPO1	transportin 1
chrX_-_15511358	26.287		PIR	pirin (iron-binding nuclear protein)
chr16_-_12010518	26.157	NM_001130007	GSPT1	G1 to S phase transition 1
chr5_+_73980968	26.121	NM_000521	HEXB	hexosaminidase B (beta polypeptide)
chr1_-_154943001	25.999	NM_001130040 NM_183001	SHC1	SHC (Src homology 2 domain containing) transforming protein 1
chr10_+_121410751	25.464	NM_004281	BAG3	BCL2-associated athanogene 3
chr3_+_184016985	25.377	NM_002808	PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr11_+_101983170	25.356	NM_001195045	YAP1	Yes-associated protein 1
chr17_+_30677187	25.314		ZNF207	zinc finger protein 207
chr4_-_74088773	25.226		ANKRD17	ankyrin repeat domain 17
chr1_-_84971848	25.140		GNG5	guanine nucleotide binding protein (G protein), gamma 5
chr10_+_121411042	25.040		BAG3	BCL2-associated athanogene 3
chr22_+_39378404	24.758	NM_004900	APOBEC3D APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
chr13_+_28196004	24.689		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr19_+_49376488	24.477		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr11_+_18415917	24.258	NM_001135239 NM_001165415 NM_001165416 NM_005566	LDHA	lactate dehydrogenase A
chr2_-_85641153	24.239		CAPG	capping protein (actin filament), gelsolin-like
chr2_+_47596286	24.054	NM_002354	EPCAM	epithelial cell adhesion molecule
chr12_-_76478410	23.997		NAP1L1	nucleosome assembly protein 1-like 1
chr7_+_116312412	23.687	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chrX_-_129244471	23.660	NM_001421	ELF4	E74-like factor 4 (ets domain transcription factor)
chr9_+_71819926	23.499	NM_001170415 NM_001170416	TJP2	tight junction protein 2 (zona occludens 2)
chr17_-_76921453	23.460	NM_003255	TIMP2	TIMP metallopeptidase inhibitor 2
chr3_+_169940223	23.370		PRKCI	protein kinase C, iota
chr3_+_184017038	23.237		PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr14_-_75643309	22.910		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr2_+_47596447	22.905		EPCAM	epithelial cell adhesion molecule
chr10_+_17270257	22.874	NM_003380	VIM	vimentin
chr10_+_17270469	22.718		VIM	vimentin
chr3_-_49395751	22.682	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr6_+_106959729	22.561	NM_001624	AIM1	absent in melanoma 1
chr14_-_23426265	22.544	NM_001166269 NM_001166270 NM_017815	HAUS4	HAUS augmin-like complex, subunit 4
chrX_-_129272014	22.505	NM_001130846	AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1
chr12_-_76478737	22.480	NM_004537 NM_139207	NAP1L1	nucleosome assembly protein 1-like 1
chr17_+_80193649	22.419	NM_001206952	SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr13_+_28195913	22.216	NM_015972 NM_152705	POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr21_-_46237978	22.111		SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr16_+_89988416	22.110	NM_001197181	TUBB3	tubulin, beta 3 class III
chr3_+_187930720	22.021	NM_005578	LPP	LIM domain containing preferred translocation partner in lipoma
chr1_-_152009467	22.014		S100A11	S100 calcium binding protein A11
chr17_-_65362635	21.889		PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr10_+_85899184	21.680	NM_014394	GHITM	growth hormone inducible transmembrane protein
chr17_-_65362667	21.435	NM_002816 NM_174871	PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr5_+_70944968	21.417		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr2_+_27851514	21.213	NM_001145047 NM_001145048 NM_001145049	GPN1	GPN-loop GTPase 1
chr10_+_121411086	21.201		BAG3	BCL2-associated athanogene 3
chr17_+_79651035	21.138		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr3_+_184038050	20.863	NM_004953	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr17_+_79650961	20.852	NM_004712	HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr5_-_137911039	20.791		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr11_-_33744497	20.729	NM_001127227	CD59	CD59 molecule, complement regulatory protein
chr10_-_13342036	20.720		PHYH	phytanoyl-CoA 2-hydroxylase
chr10_+_88854900	20.711	NM_019054	FAM35A	family with sequence similarity 35, member A
chr17_-_18161869	20.669		FLII	flightless I homolog (Drosophila)
chr14_-_75643286	20.645		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr12_-_56122840	20.419	NM_001040034 NM_001780	CD63	CD63 molecule
chr7_+_48128225	20.200	NM_181597	UPP1	uridine phosphorylase 1
chr17_+_7123246	20.156		ACADVL	acyl-CoA dehydrogenase, very long chain
chr7_+_143078358	19.937	NM_001010972 NM_003461	ZYX	zyxin
chr17_+_79651072	19.815		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr8_-_59572385	19.716		NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr20_+_35807430	19.466	NM_001135771 NM_002951	RPN2	ribophorin II
chr11_+_2924504	19.328		SLC22A18	solute carrier family 22, member 18
chr1_-_153935190	19.282		SLC39A1	solute carrier family 39 (zinc transporter), member 1
chr6_+_138725314	19.190	NM_014320	HEBP2	heme binding protein 2
chr17_+_79651042	19.088		HGS	hepatocyte growth factor-regulated tyrosine kinase substrate
chr2_+_207630310	18.946		FASTKD2	FAST kinase domains 2
chr1_+_154947147	18.925		CKS1B	CDC28 protein kinase regulatory subunit 1B
chr4_+_74606222	18.709	NM_000584	IL8	interleukin 8
chr8_-_59571920	18.575	NM_001144772	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr12_-_56122800	18.417		CD63	CD63 molecule
chr6_-_84140758	18.221		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr10_+_121411071	18.097		BAG3	BCL2-associated athanogene 3
chr3_+_69134057	18.097	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_36621751	18.089	NM_018067	MAP7D1	MAP7 domain containing 1
chr7_+_143078457	18.086		ZYX	zyxin
chr12_-_56122792	18.056		CD63	CD63 molecule
chr2_-_65593866	17.900	NM_001128210	SPRED2	sprouty-related, EVH1 domain containing 2
chr9_+_140135698	17.777	NM_006088	TUBB4B	tubulin, beta 4B class IVb
chr6_-_138428477	17.747	NM_022121	PERP	PERP, TP53 apoptosis effector
chr3_+_169940246	17.718		PRKCI	protein kinase C, iota
chr8_-_59572403	17.697	NM_003580	NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor
chr5_+_179247911	17.627		SQSTM1	sequestosome 1
chr17_-_18162018	17.454		FLII	flightless I homolog (Drosophila)
chr5_-_137911005	17.358		HSPA9	heat shock 70kDa protein 9 (mortalin)
chr1_-_45987548	17.348	NM_002574 NM_181696 NM_181697	PRDX1	peroxiredoxin 1
chr7_+_143078395	17.293		ZYX	zyxin
chr10_+_121410891	17.282		BAG3	BCL2-associated athanogene 3
chr1_+_36621457	17.266		MAP7D1	MAP7 domain containing 1
chr14_-_75643333	17.212		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr16_+_74330660	17.194	NM_002811	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr17_+_28707495	17.162	NM_001199775	CPD	carboxypeptidase D
chr21_+_33031932	17.047	NM_000454	SOD1	superoxide dismutase 1, soluble
chr14_+_103800678	16.971		EIF5	eukaryotic translation initiation factor 5
chr7_+_143078447	16.787		ZYX	zyxin
chr14_-_75643335	16.710	NM_006827	TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chrX_-_129244652	16.669	NM_001127197	ELF4	E74-like factor 4 (ets domain transcription factor)
chr6_-_84140744	16.562		ME1	malic enzyme 1, NADP(+)-dependent, cytosolic
chr18_+_55888799	16.386		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr18_+_55888838	16.328		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr17_-_7590731	16.312	NM_000546 NM_001126112 NM_001126113 NM_001126114	TP53	tumor protein p53
chr15_+_89631380	16.243	NM_007011 NM_152924	ABHD2	abhydrolase domain containing 2
chr13_+_28196024	16.241		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr1_-_108231122	16.073	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr13_+_28196029	16.008		POLR1D	polymerase (RNA) I polypeptide D, 16kDa
chr16_+_57662301	15.998	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr6_+_64231626	15.937		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr2_+_201997687	15.833	NM_001202518	CFLAR	CASP8 and FADD-like apoptosis regulator
chr15_+_44829300	15.789		EIF3J	eukaryotic translation initiation factor 3, subunit J
chr5_-_175843531	15.642	NM_001834 NM_007097	CLTB	clathrin, light chain B
chr17_+_7123149	15.618	NM_000018 NM_001033859	ACADVL	acyl-CoA dehydrogenase, very long chain
chr17_+_49230929	15.558		NME1	non-metastatic cells 1, protein (NM23A) expressed in
chr7_+_143078444	15.495		ZYX	zyxin
chr14_-_94855120	15.440	NM_000295	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.29	7.68e-14	GO:0009987	cellular process
2.63	1.24e-09	GO:0043067	regulation of programmed cell death
2.59	2.52e-09	GO:0010941	regulation of cell death
2.61	2.60e-09	GO:0042981	regulation of apoptosis
1.46	1.86e-08	GO:0044237	cellular metabolic process
1.39	1.68e-07	GO:0008152	metabolic process
2.72	8.69e-07	GO:0012501	programmed cell death
1.38	1.59e-06	GO:0050794	regulation of cellular process
1.40	1.60e-06	GO:0044238	primary metabolic process
2.70	1.65e-06	GO:0006915	apoptosis
2.30	3.21e-06	GO:0051246	regulation of protein metabolic process
1.33	3.89e-06	GO:0065007	biological regulation
2.88	5.99e-06	GO:0050878	regulation of body fluid levels
2.43	1.09e-05	GO:0008219	cell death
1.34	1.12e-05	GO:0050789	regulation of biological process
1.76	1.14e-05	GO:0048522	positive regulation of cellular process
2.42	1.28e-05	GO:0016265	death
1.63	1.61e-05	GO:0034641	cellular nitrogen compound metabolic process
8.61	1.68e-05	GO:0006521	regulation of cellular amino acid metabolic process
1.62	1.70e-05	GO:0006807	nitrogen compound metabolic process
1.69	2.16e-05	GO:0048518	positive regulation of biological process
2.29	3.95e-05	GO:0042127	regulation of cell proliferation
4.93	4.52e-05	GO:0000082	G1/S transition of mitotic cell cycle
1.73	7.20e-05	GO:0048519	negative regulation of biological process
3.46	7.32e-05	GO:0031401	positive regulation of protein modification process
2.12	8.60e-05	GO:0044248	cellular catabolic process
7.48	9.05e-05	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
7.48	9.05e-05	GO:0072395	signal transduction involved in cell cycle checkpoint
7.48	9.05e-05	GO:0072401	signal transduction involved in DNA integrity checkpoint
7.48	9.05e-05	GO:0072404	signal transduction involved in G1/S transition checkpoint
7.48	9.05e-05	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
7.48	9.05e-05	GO:0072422	signal transduction involved in DNA damage checkpoint
7.48	9.05e-05	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
7.48	9.05e-05	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
2.29	9.67e-05	GO:0009611	response to wounding
1.97	1.03e-04	GO:0009056	catabolic process
2.20	1.08e-04	GO:0032268	regulation of cellular protein metabolic process
1.70	1.42e-04	GO:0006950	response to stress
7.13	1.59e-04	GO:0033238	regulation of cellular amine metabolic process
7.13	1.59e-04	GO:0071158	positive regulation of cell cycle arrest
2.20	1.75e-04	GO:0032879	regulation of localization
2.80	1.96e-04	GO:0007596	blood coagulation
2.80	1.96e-04	GO:0050817	coagulation
1.64	1.99e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.34	1.99e-04	GO:0000216	M/G1 transition of mitotic cell cycle
2.78	2.29e-04	GO:0007599	hemostasis
5.28	2.60e-04	GO:0000084	S phase of mitotic cell cycle
6.71	3.20e-04	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
5.19	3.33e-04	GO:0051320	S phase
3.00	4.43e-04	GO:0032270	positive regulation of cellular protein metabolic process
2.56	4.57e-04	GO:0042060	wound healing
6.43	5.24e-04	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.46	6.10e-04	GO:0051716	cellular response to stimulus
3.38	6.79e-04	GO:0010035	response to inorganic substance
2.00	9.38e-04	GO:0050790	regulation of catalytic activity
1.70	9.63e-04	GO:0048523	negative regulation of cellular process
2.87	1.14e-03	GO:0051247	positive regulation of protein metabolic process
5.93	1.30e-03	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.34	1.41e-03	GO:0043085	positive regulation of catalytic activity
5.85	1.51e-03	GO:0031575	mitotic cell cycle G1/S transition checkpoint
5.85	1.51e-03	GO:0051443	positive regulation of ubiquitin-protein ligase activity
5.85	1.51e-03	GO:0071779	G1/S transition checkpoint
4.93	1.60e-03	GO:0031398	positive regulation of protein ubiquitination
2.21	1.72e-03	GO:0044093	positive regulation of molecular function
5.71	1.99e-03	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.42	2.17e-03	GO:0044260	cellular macromolecule metabolic process
6.25	2.22e-03	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.38	2.27e-03	GO:0043170	macromolecule metabolic process
3.62	2.57e-03	GO:0006916	anti-apoptosis
5.57	2.61e-03	GO:0051351	positive regulation of ligase activity
5.57	2.61e-03	GO:2000045	regulation of G1/S transition of mitotic cell cycle
4.14	2.94e-03	GO:0046039	GTP metabolic process
2.12	3.10e-03	GO:0051704	multi-organism process
5.98	3.48e-03	GO:0051352	negative regulation of ligase activity
5.98	3.48e-03	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.49	3.93e-03	GO:0007165	signal transduction
4.29	3.96e-03	GO:0010565	regulation of cellular ketone metabolic process
5.31	4.38e-03	GO:0030330	DNA damage response, signal transduction by p53 class mediator
2.17	4.99e-03	GO:0031399	regulation of protein modification process
1.71	6.22e-03	GO:0044281	small molecule metabolic process
4.14	6.30e-03	GO:0006184	GTP catabolic process
5.07	7.14e-03	GO:0051438	regulation of ubiquitin-protein ligase activity
2.65	8.04e-03	GO:0008285	negative regulation of cell proliferation
4.62	8.19e-03	GO:0042770	signal transduction in response to DNA damage
1.44	8.81e-03	GO:0023052	signaling
2.98	9.78e-03	GO:0051329	interphase of mitotic cell cycle
4.86	1.13e-02	GO:0051340	regulation of ligase activity
1.50	1.15e-02	GO:0019538	protein metabolic process
3.94	1.16e-02	GO:0030335	positive regulation of cell migration
3.94	1.16e-02	GO:2000147	positive regulation of cell motility
3.15	1.17e-02	GO:0030334	regulation of cell migration
2.93	1.30e-02	GO:0051325	interphase
3.11	1.40e-02	GO:2000145	regulation of cell motility
1.77	1.61e-02	GO:0065009	regulation of molecular function
3.81	1.76e-02	GO:0040017	positive regulation of locomotion
1.29	1.80e-02	GO:0050896	response to stimulus
2.36	2.27e-02	GO:0044265	cellular macromolecule catabolic process
1.54	2.28e-02	GO:0044267	cellular protein metabolic process
3.71	2.42e-02	GO:0010498	proteasomal protein catabolic process
3.71	2.42e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.24	2.49e-02	GO:0009057	macromolecule catabolic process
3.68	2.62e-02	GO:0051272	positive regulation of cellular component movement
4.81	3.02e-02	GO:0031397	negative regulation of protein ubiquitination
2.22	3.20e-02	GO:0051726	regulation of cell cycle
4.35	3.57e-02	GO:0090068	positive regulation of cell cycle process
3.78	3.76e-02	GO:0031396	regulation of protein ubiquitination
4.31	3.93e-02	GO:0000077	DNA damage checkpoint
3.99	4.14e-02	GO:0007093	mitotic cell cycle checkpoint
5.07	4.55e-02	GO:0002576	platelet degranulation
1.82	4.82e-02	GO:0031325	positive regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.42	1.18e-14	GO:0005737	cytoplasm
1.24	1.95e-10	GO:0044424	intracellular part
1.22	2.59e-09	GO:0005622	intracellular
7.85	2.15e-06	GO:0000502	proteasome complex
1.34	1.01e-04	GO:0044444	cytoplasmic part
1.53	5.82e-04	GO:0043234	protein complex
1.22	9.91e-04	GO:0043227	membrane-bounded organelle
1.21	1.40e-03	GO:0043231	intracellular membrane-bounded organelle
1.18	4.05e-03	GO:0043226	organelle
1.18	5.24e-03	GO:0043229	intracellular organelle
1.39	1.43e-02	GO:0032991	macromolecular complex
16.91	1.51e-02	GO:0005838	proteasome regulatory particle
2.00	2.46e-02	GO:0031967	organelle envelope
1.96	3.48e-02	GO:0031975	envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.51	1.44e-16	GO:0005515	protein binding
1.18	1.92e-06	GO:0005488	binding
5.23	2.65e-03	GO:0070851	growth factor receptor binding
3.14	1.16e-02	GO:0003924	GTPase activity