Motif ID: BACH2.p2

Z-value: 2.053


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BACH2chr6_-_91006580-0.421.4e-10Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_223889253 129.570 NM_001146068
 CAPN2
calpain 2, (m/II) large subunit
chr17_+_30771520 96.747 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr6_-_31704070 78.399 CLIC1
chloride intracellular channel 1
chr1_-_152009440 76.015 S100A11
S100 calcium binding protein A11
chr1_-_152009406 73.956 S100A11
S100 calcium binding protein A11
chr6_-_31704318 73.616 NM_001288
 CLIC1
chloride intracellular channel 1
chr6_-_31704304 73.044 CLIC1
chloride intracellular channel 1
chr6_-_31704272 72.090 CLIC1
chloride intracellular channel 1
chr6_-_31704281 72.001 CLIC1
chloride intracellular channel 1
chr6_-_31704287 71.843 CLIC1
chloride intracellular channel 1
chr6_-_31704093 71.027 CLIC1
chloride intracellular channel 1
chr11_-_2950593 63.965 NM_003311
 PHLDA2
pleckstrin homology-like domain, family A, member 2
chr1_+_156084541 63.865 LMNA
lamin A/C
chr7_-_96339074 56.889 SHFM1
split hand/foot malformation (ectrodactyly) type 1
chr17_+_30771532 56.419 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr7_-_7758237 55.551 NM_002947
 RPA3
replication protein A3, 14kDa
chr17_+_30771494 55.160 NM_002815
 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_30771485 54.503 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_+_30771522 51.242 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_+_26606621 49.586 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 110 entries
enrichment   p-value GO term description
8.61 1.68e-05 GO:0006521 regulation of cellular amino acid metabolic process
7.48 9.05e-05 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
7.48 9.05e-05 GO:0072395 signal transduction involved in cell cycle checkpoint
7.48 9.05e-05 GO:0072401 signal transduction involved in DNA integrity checkpoint
7.48 9.05e-05 GO:0072404 signal transduction involved in G1/S transition checkpoint
7.48 9.05e-05 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
7.48 9.05e-05 GO:0072422 signal transduction involved in DNA damage checkpoint
7.48 9.05e-05 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
7.48 9.05e-05 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
7.13 1.59e-04 GO:0033238 regulation of cellular amine metabolic process
7.13 1.59e-04 GO:0071158 positive regulation of cell cycle arrest
6.71 3.20e-04 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
6.43 5.24e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.34 1.99e-04 GO:0000216 M/G1 transition of mitotic cell cycle
6.25 2.22e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.98 3.48e-03 GO:0051352 negative regulation of ligase activity
5.98 3.48e-03 GO:0051444 negative regulation of ubiquitin-protein ligase activity
5.93 1.30e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.85 1.51e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
5.85 1.51e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
16.91 1.51e-02 GO:0005838 proteasome regulatory particle
7.85 2.15e-06 GO:0000502 proteasome complex
2.00 2.46e-02 GO:0031967 organelle envelope
1.96 3.48e-02 GO:0031975 envelope
1.53 5.82e-04 GO:0043234 protein complex
1.42 1.18e-14 GO:0005737 cytoplasm
1.39 1.43e-02 GO:0032991 macromolecular complex
1.34 1.01e-04 GO:0044444 cytoplasmic part
1.24 1.95e-10 GO:0044424 intracellular part
1.22 2.59e-09 GO:0005622 intracellular
1.22 9.91e-04 GO:0043227 membrane-bounded organelle
1.21 1.40e-03 GO:0043231 intracellular membrane-bounded organelle
1.18 4.05e-03 GO:0043226 organelle
1.18 5.24e-03 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
5.23 2.65e-03 GO:0070851 growth factor receptor binding
3.14 1.16e-02 GO:0003924 GTPase activity
1.51 1.44e-16 GO:0005515 protein binding
1.18 1.92e-06 GO:0005488 binding