Motif ID: BPTF.p2

Z-value: 2.079


Transcription factors associated with BPTF.p2:

Gene SymbolEntrez IDGene Name
BPTF 2186 bromodomain PHD finger transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
BPTFchr17_+_65822206,
chr17_+_65822242		0.483.2e-14Click!


Activity profile for motif BPTF.p2.

activity profile for motif BPTF.p2


Sorted Z-values histogram for motif BPTF.p2

Sorted Z-values for motif BPTF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BPTF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_216176678 64.286 NM_004044
 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr11_-_77348758 56.345 NM_001293
 CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr11_-_67450536 47.447 RPL37
ribosomal protein L37
chr2_+_216176808 44.223 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr15_-_72501017 43.772 PKM2
pyruvate kinase, muscle
chr15_-_76603806 42.914 NM_000126
NM_001127716
 ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr14_+_67656109 40.658 NM_173526
 FAM71D
family with sequence similarity 71, member D
chr5_+_132428394 39.286 HSPA4
heat shock 70kDa protein 4
chr21_+_30400229 37.346 USP16
ubiquitin specific peptidase 16
chr10_-_98321823 34.794 TM9SF3
transmembrane 9 superfamily member 3
chr7_+_56019552 34.721 NM_015969
 MRPS17
mitochondrial ribosomal protein S17
chr13_+_37574916 34.417 EXOSC8
exosome component 8
chr6_-_30712294 33.860 NM_003897
 IER3
immediate early response 3
chr12_-_58146118 33.721 NM_000075
 CDK4
cyclin-dependent kinase 4
chr15_-_76603791 33.659 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr2_+_85804689 32.583 VAMP8
vesicle-associated membrane protein 8 (endobrevin)
chrX_+_123234462 32.509 STAG2
stromal antigen 2
chr9_+_75766794 32.227 ANXA1
annexin A1
chr14_+_102276125 32.221 NM_002719
NM_178586
NM_178587
 PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr10_-_98336445 30.816 TM9SF3
transmembrane 9 superfamily member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 128 entries
enrichment   p-value GO term description
7.64 1.08e-02 GO:0040001 establishment of mitotic spindle localization
3.15 1.87e-04 GO:0022618 ribonucleoprotein complex assembly
3.08 3.26e-04 GO:0000236 mitotic prometaphase
2.97 1.54e-07 GO:0000082 G1/S transition of mitotic cell cycle
2.97 7.21e-04 GO:0071826 ribonucleoprotein complex subunit organization
2.89 2.80e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.85 1.53e-04 GO:0032984 macromolecular complex disassembly
2.85 1.53e-04 GO:0034623 cellular macromolecular complex disassembly
2.85 2.79e-03 GO:0006415 translational termination
2.84 5.10e-03 GO:0019080 viral genome expression
2.84 5.10e-03 GO:0019083 viral transcription
2.82 1.95e-04 GO:0000084 S phase of mitotic cell cycle
2.79 9.36e-05 GO:0031018 endocrine pancreas development
2.79 1.70e-03 GO:0043241 protein complex disassembly
2.79 1.70e-03 GO:0043624 cellular protein complex disassembly
2.77 3.09e-04 GO:0051320 S phase
2.77 2.15e-02 GO:0000216 M/G1 transition of mitotic cell cycle
2.77 2.15e-02 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.77 2.15e-02 GO:0071779 G1/S transition checkpoint
2.70 7.70e-09 GO:0000075 cell cycle checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
3.80 1.30e-02 GO:0030532 small nuclear ribonucleoprotein complex
2.35 1.65e-03 GO:0005681 spliceosomal complex
2.21 2.89e-02 GO:0044455 mitochondrial membrane part
2.16 1.02e-03 GO:0005840 ribosome
2.09 7.94e-11 GO:0030529 ribonucleoprotein complex
2.07 4.01e-02 GO:0000775 chromosome, centromeric region
2.05 4.02e-04 GO:0005635 nuclear envelope
2.03 1.05e-02 GO:0005819 spindle
1.95 6.92e-09 GO:0005694 chromosome
1.92 6.39e-03 GO:0000785 chromatin
1.92 1.60e-02 GO:0000228 nuclear chromosome
1.90 1.82e-06 GO:0044427 chromosomal part
1.88 2.00e-02 GO:0016604 nuclear body
1.82 1.69e-17 GO:0005654 nucleoplasm
1.77 1.37e-22 GO:0031981 nuclear lumen
1.76 2.88e-27 GO:0044428 nuclear part
1.74 3.95e-07 GO:0044451 nucleoplasm part
1.71 2.39e-06 GO:0031967 organelle envelope
1.71 3.83e-04 GO:0005730 nucleolus
1.70 9.98e-25 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.34 6.77e-03 GO:0051287 NAD binding
2.55 3.37e-02 GO:0016651 oxidoreductase activity, acting on NADH or NADPH
2.34 1.00e-03 GO:0003735 structural constituent of ribosome
2.24 5.64e-03 GO:0003714 transcription corepressor activity
1.86 1.98e-04 GO:0003712 transcription cofactor activity
1.86 2.20e-04 GO:0000988 protein binding transcription factor activity
1.86 2.20e-04 GO:0000989 transcription factor binding transcription factor activity
1.80 8.15e-10 GO:0003723 RNA binding
1.72 1.66e-02 GO:0016887 ATPase activity
1.54 1.74e-03 GO:0019899 enzyme binding
1.45 3.60e-02 GO:0017111 nucleoside-triphosphatase activity
1.44 4.13e-02 GO:0016462 pyrophosphatase activity
1.44 4.88e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.38 9.44e-40 GO:0005515 protein binding
1.33 3.75e-05 GO:0000166 nucleotide binding
1.28 9.65e-06 GO:0003676 nucleic acid binding
1.17 5.86e-25 GO:0005488 binding
1.17 1.67e-03 GO:0003824 catalytic activity