Motif ID: CDC5L.p2

Z-value: 0.959


Transcription factors associated with CDC5L.p2:

Gene SymbolEntrez IDGene Name
CDC5L 988 CDC5 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDC5Lchr6_+_44355440-0.394.1e-09Click!


Activity profile for motif CDC5L.p2.

activity profile for motif CDC5L.p2


Sorted Z-values histogram for motif CDC5L.p2

Sorted Z-values for motif CDC5L.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDC5L.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_21646685 18.935


chr5_-_138210992 18.278 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr16_-_71610948 16.408 NM_000353
 TAT
tyrosine aminotransferase
chr6_-_32557431 15.747 NM_001243965
NM_002124
 HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr12_-_16759939 14.475 NM_001243613
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_-_138211054 14.396 NM_015564
 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr9_-_110252045 13.119 NM_004235
 KLF4
Kruppel-like factor 4 (gut)
chr12_-_91573264 12.924 NM_133503
 DCN
decorin
chr4_+_62362838 12.129 NM_015236
 LPHN3
latrophilin 3
chr17_-_2996289 11.546 NM_002548
 OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr12_-_91398744 11.174 EPYC
epiphycan
chr1_+_198608216 9.910 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_182357757 9.525 GLUL
glutamate-ammonia ligase
chr3_+_122044010 9.268 NM_005213
 CSTA
cystatin A (stefin A)
chr8_+_1952875 9.263 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr3_+_35721115 9.146 NM_001025068
NM_001025069
 ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr12_-_91576579 9.077 DCN
decorin
chr12_-_16759733 8.655 NM_001243610
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr15_+_32933869 8.270 NM_001144757
NM_003020
 SCG5

secretogranin V (7B2 protein)

chr6_-_32497925 8.121 NM_002125
 HLA-DRB5
major histocompatibility complex, class II, DR beta 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
8.15 2.22e-02 GO:0018149 peptide cross-linking
3.15 1.53e-03 GO:0002253 activation of immune response
2.69 3.53e-05 GO:0050776 regulation of immune response
2.55 3.32e-03 GO:0045087 innate immune response
2.51 1.03e-05 GO:0042060 wound healing
2.48 1.38e-07 GO:0006955 immune response
2.47 3.34e-04 GO:0007596 blood coagulation
2.47 3.34e-04 GO:0050817 coagulation
2.45 3.96e-04 GO:0007599 hemostasis
2.26 1.04e-06 GO:0009611 response to wounding
2.26 1.56e-03 GO:0050878 regulation of body fluid levels
2.17 5.48e-04 GO:0002682 regulation of immune system process
2.10 2.70e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
1.99 4.98e-06 GO:0002376 immune system process
1.97 3.89e-03 GO:0006952 defense response
1.66 6.22e-04 GO:0007166 cell surface receptor linked signaling pathway
1.57 1.43e-03 GO:0065008 regulation of biological quality
1.56 1.13e-02 GO:0048583 regulation of response to stimulus
1.54 7.86e-04 GO:0006950 response to stress
1.50 1.68e-06 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.57 1.51e-03 GO:0005578 proteinaceous extracellular matrix
2.39 3.56e-08 GO:0005615 extracellular space
2.35 1.56e-10 GO:0044421 extracellular region part
2.34 4.20e-03 GO:0031012 extracellular matrix
2.16 7.70e-10 GO:0005887 integral to plasma membrane
2.12 2.10e-09 GO:0031226 intrinsic to plasma membrane
1.91 3.25e-11 GO:0005576 extracellular region
1.80 1.60e-09 GO:0044459 plasma membrane part
1.44 6.09e-07 GO:0071944 cell periphery
1.42 5.05e-06 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
29.12 1.64e-02 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor
16.18 2.09e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
6.55 2.48e-03 GO:0003823 antigen binding
2.70 4.57e-02 GO:0005125 cytokine activity
1.95 8.91e-03 GO:0005509 calcium ion binding
1.77 4.40e-03 GO:0005102 receptor binding