Motif ID: CDX1,2,4.p2

Z-value: 1.095


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
CDX1 1044 caudal type homeobox 1
CDX2 1045 caudal type homeobox 2
CDX4 1046 caudal type homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CDX2chr13_-_28543290-0.135.6e-02Click!
CDX1chr5_+_149546340-0.045.8e-01Click!
CDX4chrX_+_726670890.036.9e-01Click!


Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_23054862 21.901 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr18_-_47814691 20.055 NM_001101654
NM_014593
 CXXC1

CXXC finger protein 1

chr19_-_39826676 16.200 NM_004877
 GMFG
glia maturation factor, gamma
chr12_-_10282680 15.110 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
 CLEC7A





C-type lectin domain family 7, member A





chr19_-_36399120 14.838 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_-_36399183 14.620 TYROBP
TYRO protein tyrosine kinase binding protein
chr19_-_36399205 14.093 NM_001173514
NM_001173515
NM_003332
NM_198125
 TYROBP



TYRO protein tyrosine kinase binding protein



chr12_+_54892567 13.676 NM_001184976
 NCKAP1L
NCK-associated protein 1-like
chr10_+_70847857 12.485 SRGN
serglycin
chr11_+_63304272 12.235 NM_004585
 RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr11_-_104905849 12.180 CASP1
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
chr22_+_37678565 11.672 CYTH4
cytohesin 4
chr1_+_198608136 11.498 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_+_198608216 10.403 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_10562744 9.995 NM_001199805
 KLRC4-KLRK1
KLRC4-KLRK1 readthrough
chr13_-_99959649 9.620 NM_004951
 GPR183
G protein-coupled receptor 183
chr11_-_104972147 9.523 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
 CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr12_-_10542616 9.426 NM_007360
 KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr3_-_105421044 9.215 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr14_-_107179043 9.023 IGHA1
immunoglobulin heavy constant alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
3.84 2.21e-02 GO:0006968 cellular defense response
2.93 2.58e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.82 4.72e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.57 3.75e-06 GO:0050778 positive regulation of immune response
2.57 1.99e-04 GO:0002253 activation of immune response
2.51 8.14e-03 GO:0002757 immune response-activating signal transduction
2.46 1.31e-02 GO:0002764 immune response-regulating signaling pathway
2.41 2.43e-08 GO:0050776 regulation of immune response
2.40 1.42e-02 GO:0046649 lymphocyte activation
2.40 2.06e-02 GO:0050867 positive regulation of cell activation
2.38 1.46e-03 GO:0045321 leukocyte activation
2.36 4.15e-02 GO:0002696 positive regulation of leukocyte activation
2.22 1.89e-11 GO:0006955 immune response
2.18 1.64e-05 GO:0002684 positive regulation of immune system process
2.17 7.88e-03 GO:0006954 inflammatory response
2.07 1.50e-09 GO:0006952 defense response
2.03 5.59e-03 GO:0045087 innate immune response
2.02 1.68e-04 GO:0001775 cell activation
2.00 1.02e-06 GO:0002682 regulation of immune system process
1.97 4.92e-13 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.41 3.11e-02 GO:0031226 intrinsic to plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
6.91 1.35e-02 GO:0008329 pattern recognition receptor activity
5.56 1.04e-05 GO:0003823 antigen binding
3.44 3.65e-02 GO:0004896 cytokine receptor activity
2.34 5.47e-03 GO:0005529 sugar binding
1.91 6.82e-03 GO:0030246 carbohydrate binding
1.08 6.00e-04 GO:0005488 binding