Motif ID: CEBPA,B_DDIT3.p2

Z-value: 1.001


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CEBPAchr19_-_337934410.371.2e-08Click!
DDIT3chr12_-_579142870.187.6e-03Click!
CEBPBchr20_+_488071190.171.1e-02Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_140013285 16.597 NM_001040021
NM_001174104
NM_001174105
 CD14


CD14 molecule


chr5_-_140012730 16.479 CD14
CD14 molecule
chr3_+_186330859 16.077 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330844 16.041 NM_001622
 AHSG
alpha-2-HS-glycoprotein
chr3_+_186330711 13.985 AHSG
alpha-2-HS-glycoprotein
chr19_+_45452427 10.149 APOC2
apolipoprotein C-II
chr3_+_157154579 10.032 NM_002852
 PTX3
pentraxin 3, long
chr2_-_216300770 9.897 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr17_-_64225496 9.490 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_140013034 8.478 NM_000591
 CD14
CD14 molecule
chr9_+_117085302 7.549 NM_000607
 ORM1
orosomucoid 1
chr16_+_56966025 7.324 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr11_+_114167168 7.267 NNMT
nicotinamide N-methyltransferase
chrX_-_13835187 6.705 GPM6B
glycoprotein M6B
chr9_+_117092068 6.701 NM_000608
 ORM2
orosomucoid 2
chr2_-_113594325 6.619 NM_000576
 IL1B
interleukin 1, beta
chr11_-_33913835 6.492 NM_005574
 LMO2
LIM domain only 2 (rhombotin-like 1)
chr11_+_114167197 6.041 NNMT
nicotinamide N-methyltransferase
chr17_-_34524054 6.011 NM_001001437
NM_021006
 CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr9_-_77502262 5.627 NM_001177311
 TRPM6
transient receptor potential cation channel, subfamily M, member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
15.68 1.46e-02 GO:0010574 regulation of vascular endothelial growth factor production
10.08 3.07e-02 GO:0030195 negative regulation of blood coagulation
9.73 3.80e-02 GO:0050819 negative regulation of coagulation
7.71 7.70e-04 GO:0072376 protein activation cascade
6.47 1.30e-03 GO:0006959 humoral immune response
6.05 2.25e-02 GO:0032102 negative regulation of response to external stimulus
5.80 3.18e-02 GO:0050671 positive regulation of lymphocyte proliferation
5.72 3.55e-02 GO:0032946 positive regulation of mononuclear cell proliferation
5.65 3.96e-02 GO:0070665 positive regulation of leukocyte proliferation
4.71 5.42e-03 GO:0001819 positive regulation of cytokine production
4.32 5.83e-05 GO:0032101 regulation of response to external stimulus
4.25 3.51e-06 GO:0006954 inflammatory response
4.15 1.09e-03 GO:0072507 divalent inorganic cation homeostasis
4.14 1.03e-02 GO:0010876 lipid localization
4.05 3.14e-03 GO:0055074 calcium ion homeostasis
4.05 3.14e-03 GO:0072503 cellular divalent inorganic cation homeostasis
3.92 9.62e-03 GO:0006874 cellular calcium ion homeostasis
3.87 2.16e-15 GO:0006955 immune response
3.87 1.42e-03 GO:0008202 steroid metabolic process
3.59 1.15e-03 GO:0055065 metal ion homeostasis

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
9.80 2.46e-02 GO:0043195 terminal button
8.23 3.58e-03 GO:0043679 axon terminus
7.84 4.99e-03 GO:0044306 neuron projection terminus
4.95 3.91e-02 GO:0033267 axon part
3.10 2.84e-10 GO:0005615 extracellular space
2.68 3.47e-09 GO:0044421 extracellular region part
2.37 3.35e-14 GO:0005576 extracellular region
2.22 1.25e-03 GO:0005624 membrane fraction
2.21 1.03e-03 GO:0005626 insoluble fraction
1.95 3.60e-03 GO:0000267 cell fraction
1.83 1.10e-02 GO:0005887 integral to plasma membrane
1.80 1.71e-02 GO:0031226 intrinsic to plasma membrane
1.55 2.97e-02 GO:0044459 plasma membrane part
1.47 3.28e-04 GO:0005886 plasma membrane
1.46 3.99e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
9.41 5.08e-04 GO:0003823 antigen binding
4.24 3.95e-02 GO:0008201 heparin binding
3.85 1.10e-02 GO:0001871 pattern binding
3.85 1.10e-02 GO:0030247 polysaccharide binding
3.40 3.94e-02 GO:0005126 cytokine receptor binding
1.79 1.74e-03 GO:0004872 receptor activity
1.66 4.94e-03 GO:0004871 signal transducer activity
1.66 4.94e-03 GO:0060089 molecular transducer activity