Motif ID: CGUGUCU

Z-value: 0.646


Mature miRNA associated with seed CGUGUCU:

NamemiRBase Accession
hsa-miR-187 MIMAT0000262



Activity profile for motif CGUGUCU.

activity profile for motif CGUGUCU


Sorted Z-values histogram for motif CGUGUCU

Sorted Z-values for motif CGUGUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of CGUGUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_9268522 11.832 NM_000014
A2M
alpha-2-macroglobulin
chr1_-_52831817 7.898 NM_032449
CC2D1B
coiled-coil and C2 domain containing 1B
chr19_-_57336373 7.006 NM_001146186
PEG3
paternally expressed 3
chr12_+_7167979 6.778 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr17_-_42992852 5.847 NM_001131019
NM_001242376
NM_002055
GFAP


glial fibrillary acidic protein


chr3_+_101568325 5.798 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_+_16607181 5.434 NM_032207
C19orf44
chromosome 19 open reading frame 44
chr3_+_101546833 4.966 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr17_+_73106028 4.278 NM_024585
ARMC7
armadillo repeat containing 7
chr16_-_19896105 4.241 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr19_-_17799005 4.220 NM_001080421
UNC13A
unc-13 homolog A (C. elegans)
chr9_-_16870719 4.105 NM_017637
BNC2
basonuclin 2
chr1_+_33352071 4.014 NM_002143
HPCA
hippocalcin
chr18_-_74207145 3.836 NM_014643
ZNF516
zinc finger protein 516
chr7_+_99699129 3.793 NM_004722
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr12_-_123451031 3.740 NM_001243013
NM_001243014
NM_019624
NM_019625
NM_203444
ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr1_-_54665670 3.709 NM_001031672
CYB5RL
cytochrome b5 reductase-like
chr20_-_50384899 3.600 NM_006045
ATP9A
ATPase, class II, type 9A
chr6_-_149806116 3.557 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr8_+_11561710 3.474 NM_002052
GATA4
GATA binding protein 4
chr17_-_34308455 3.449 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr4_+_41258895 3.441 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr16_-_15950850 3.432 NM_001040113
NM_001040114
NM_002474
NM_022844
MYH11



myosin, heavy chain 11, smooth muscle



chr19_+_3094266 3.383 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr12_-_6055397 3.374 NM_020373
ANO2
anoctamin 2
chr1_-_202679415 3.304 NM_177402
SYT2
synaptotagmin II
chr20_+_34742656 3.227 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr15_-_29862926 3.176 NM_015307
FAM189A1
family with sequence similarity 189, member A1
chr11_+_126226095 3.164 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_32671235 3.132 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr11_-_75236418 3.111 NM_030792
GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr1_-_24239758 3.109 NM_001841
CNR2
cannabinoid receptor 2 (macrophage)
chr19_-_57352055 3.071 NM_001146326
NM_001146327
NM_015363
NM_001146184
NM_001146185
NM_001146187
NM_006210
ZIM2


PEG3



zinc finger, imprinted 2


paternally expressed 3



chr1_+_35225341 3.036 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr1_-_202612580 2.962 NM_001136504
SYT2
synaptotagmin II
chr7_+_4721722 2.960 NM_001037165
FOXK1
forkhead box K1
chr4_+_124320664 2.937 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr7_+_45614081 2.936 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chrX_-_3264680 2.875 NM_015419
MXRA5
matrix-remodelling associated 5
chr4_+_124317884 2.864 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_+_31799030 2.778 NM_178140
PDZD2
PDZ domain containing 2
chr14_+_24837225 2.777 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr9_-_101470836 2.714 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr19_+_35521591 2.680 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr14_+_24836144 2.673 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr5_+_65017993 2.637 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr17_+_17206626 2.602 NM_020201
NT5M
5',3'-nucleotidase, mitochondrial
chr17_-_71640226 2.592 NM_001144952
SDK2
sidekick cell adhesion molecule 2
chr3_+_195447751 2.579 NM_152673
MUC20
mucin 20, cell surface associated
chr10_+_102222797 2.574 NM_003393
WNT8B
wingless-type MMTV integration site family, member 8B
chr3_+_13590624 2.566 NM_001004019
NM_001998
FBLN2

fibulin 2

chr5_-_101631965 2.548 NM_180991
SLCO4C1
solute carrier organic anion transporter family, member 4C1
chr5_+_71403040 2.521 NM_005909
MAP1B
microtubule-associated protein 1B
chr22_-_19109912 2.500 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr5_-_154230212 2.497 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr19_-_4559713 2.474 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr19_+_19431622 2.429 NM_015329
MAU2
MAU2 chromatid cohesion factor homolog (C. elegans)
chr3_+_13610239 2.429 NM_001165035
FBLN2
fibulin 2
chr20_+_34700257 2.418 NM_177996
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr7_+_4815258 2.405 NM_014855
KIAA0415
KIAA0415
chr19_-_5978225 2.379 NM_003624
NM_007320
NM_007322
RANBP3


RAN binding protein 3


chr12_-_115121939 2.347 NM_005996
NM_016569
TBX3

T-box 3

chr19_+_2841432 2.331 NM_001172775
NM_152791
ZNF555

zinc finger protein 555

chr3_-_185826748 2.316 NM_004454
ETV5
ets variant 5
chr13_+_28712379 2.308 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chrX_-_47342344 2.282 NM_007130
NM_153380
ZNF41

zinc finger protein 41

chr5_+_150827138 2.270 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr2_-_237076613 2.227 NM_001485
GBX2
gastrulation brain homeobox 2
chr17_-_31203889 2.185 NM_015194
MYO1D
myosin ID
chr17_-_10101854 2.163 NM_201433
GAS7
growth arrest-specific 7
chr3_-_14583587 2.138 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr1_-_31381436 2.120 NM_014654
SDC3
syndecan 3
chr19_-_46142662 2.085 NM_012155
EML2
echinoderm microtubule associated protein like 2
chr11_-_74109417 2.068 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr19_+_55281262 2.059 NM_014218
KIR2DL1
KIR2DS4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chrX_+_122318095 2.019 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr8_+_1922030 2.018 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr14_+_24838301 2.007 NM_001198966
NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
chr4_+_72052354 2.007 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr2_-_240322620 1.977 NM_006037
HDAC4
histone deacetylase 4
chr2_-_145090038 1.953 NM_001164629
GTDC1
glycosyltransferase-like domain containing 1
chr15_-_33360084 1.941 NM_001103184
FMN1
formin 1
chr19_-_46148606 1.910 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr22_-_44708730 1.887 NM_001099294
KIAA1644
KIAA1644
chr19_-_18335302 1.864 NM_001098819
PDE4C
phosphodiesterase 4C, cAMP-specific
chrX_+_49178508 1.804 NM_001098406
GAGE1
GAGE4
GAGE5
GAGE6
GAGE12J
G antigen 1
G antigen 4
G antigen 5
G antigen 6
G antigen 12J
chr16_+_55689541 1.786 NM_001172501
SLC6A2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr16_+_55705582 1.771 NM_001172502
SLC6A2
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr22_+_41957011 1.757 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr17_+_54911452 1.723 NM_003647
DGKE
diacylglycerol kinase, epsilon 64kDa
chr19_-_18337234 1.721 NM_001098818
PDE4C
phosphodiesterase 4C, cAMP-specific
chr14_-_75422466 1.719 NM_001207012
NM_002632
PGF

placental growth factor

chr17_-_9862765 1.717 NM_003644
GAS7
growth arrest-specific 7
chr13_+_113344354 1.693 NM_015205
NM_032189
ATP11A

ATPase, class VI, type 11A

chr3_+_195451097 1.689 NM_001098516
MUC20
mucin 20, cell surface associated
chr11_-_44331612 1.683 NM_021926
ALX4
ALX homeobox 4
chr5_-_39425297 1.657 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr20_+_60813577 1.644 NM_014835
NM_144498
OSBPL2

oxysterol binding protein-like 2

chr16_+_55690351 1.641 NM_001043
NM_001172504
SLC6A2

solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

chr19_-_11591439 1.639 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr12_+_72666462 1.633 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr19_+_55344130 1.609 NM_012314
KIR2DS4
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr19_+_55249973 1.603 NM_015868
KIR2DL3
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr7_-_6312137 1.566 NM_004227
CYTH3
cytohesin 3
chr17_-_48546174 1.565 NM_001267
CHAD
chondroadherin
chr19_-_7293876 1.482 NM_000208
NM_001079817
INSR

insulin receptor

chr3_+_121613170 1.472 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr16_+_1756161 1.467 NM_001040439
NM_015133
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr2_-_127963342 1.428 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr7_+_128470462 1.385 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr16_-_4166185 1.382 NM_001116
ADCY9
adenylate cyclase 9
chr14_-_92506284 1.376 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr19_-_46146984 1.373 NM_001193269
EML2
echinoderm microtubule associated protein like 2
chr3_+_185000714 1.370 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr17_-_46651809 1.327 NM_002146
HOXB3
homeobox B3
chr4_+_72204769 1.326 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr1_+_178062829 1.302 NM_170692
RASAL2
RAS protein activator like 2
chr3_+_11267666 1.272 NM_001098211
HRH1
histamine receptor H1
chr7_-_100860991 1.259 NM_001084
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr18_-_24442534 1.243 NM_004028
AQP4
aquaporin 4
chr3_+_11178778 1.197 NM_001098213
HRH1
histamine receptor H1
chrX_-_57936853 1.186 NM_007156
ZXDA
zinc finger, X-linked, duplicated A
chr20_-_35374530 1.153 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr1_+_207226594 1.151 NM_001018053
NM_006212
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr19_+_18942742 1.104 NM_002911
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr12_-_118541655 1.071 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr21_-_43786602 1.058 NM_003225
TFF1
trefoil factor 1
chr18_+_59992519 1.030 NM_003839
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr1_+_57110745 1.007 NM_006252
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chrX_+_135614310 0.997 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr11_-_85376159 0.962 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chr2_-_69870976 0.949 NM_014911
AAK1
AP2 associated kinase 1
chr19_+_55315065 0.944 NM_001080770
NM_001080772
NM_002255
KIR2DL4


killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4


chr17_-_2304217 0.931 NM_020310
MNT
MAX binding protein
chr3_-_183145854 0.923 NM_015078
MCF2L2
MCF.2 cell line derived transforming sequence-like 2
chrX_+_49188092 0.902 NM_012196
NM_001127200
NM_001098412
GAGE8
GAGE2C
GAGE2E
GAGE13
GAGE2A
G antigen 8
G antigen 2C
G antigen 2E
G antigen 13
G antigen 2A
chr8_+_143545376 0.888 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr3_-_46037299 0.866 NM_024513
FYCO1
FYVE and coiled-coil domain containing 1
chr2_+_5832778 0.843 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr1_+_24829299 0.836 NM_001251977
NM_001251981
NM_001251983
NM_013441
RCAN3



RCAN family member 3



chr13_+_77566043 0.820 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr20_-_32274154 0.812 NM_005225
E2F1
E2F transcription factor 1
chr5_-_1445510 0.809 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr12_+_3186520 0.790 NM_001168320
NM_006675
TSPAN9

tetraspanin 9

chr19_+_2164119 0.761 NM_032482
DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chrX_+_49160124 0.751 NM_001098413
GAGE10
G antigen 10
chr10_+_103113807 0.720 NM_003939
NM_033637
BTRC

beta-transducin repeat containing

chr17_-_73257703 0.712 NM_014001
NM_138619
GGA3

golgi-associated, gamma adaptin ear containing, ARF binding protein 3

chr20_-_32700082 0.682 NM_003908
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr9_-_126692184 0.666 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr1_+_26758772 0.650 NM_001243564
NM_001243565
NM_024887
NM_205861
DHDDS



dehydrodolichyl diphosphate synthase



chr1_+_178310605 0.639 NM_004841
RASAL2
RAS protein activator like 2
chr7_-_71877359 0.639 NM_031468
CALN1
calneuron 1
chr19_-_36054559 0.618 NM_000704
ATP4A
ATPase, H+/K+ exchanging, alpha polypeptide
chr1_+_23037329 0.617 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr16_+_811049 0.610 NM_013404
MSLN
mesothelin
chr3_+_11294384 0.594 NM_000861
HRH1
histamine receptor H1
chr1_-_179112178 0.581 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr11_-_119599253 0.578 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr11_-_35441099 0.578 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_-_179198814 0.559 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr9_+_129089092 0.482 NM_001011703
NM_033446
FAM125B

family with sequence similarity 125, member B

chr19_+_48325098 0.472 NM_000554
CRX
cone-rod homeobox
chr3_+_185080835 0.429 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr14_-_100070442 0.428 NM_001144995
CCDC85C
coiled-coil domain containing 85C
chr2_-_144994905 0.426 NM_024659
GTDC1
glycosyltransferase-like domain containing 1
chr19_+_54466289 0.409 NM_031895
CACNG8
calcium channel, voltage-dependent, gamma subunit 8
chr17_-_9940004 0.407 NM_201432
GAS7
growth arrest-specific 7
chr2_+_191745546 0.404 NM_014905
GLS
glutaminase
chr11_+_3666357 0.366 NM_004314
ART1
ADP-ribosyltransferase 1
chr17_+_35294771 0.325 NM_005568
LHX1
LIM homeobox 1
chr19_-_18359009 0.294 NM_000923
PDE4C
phosphodiesterase 4C, cAMP-specific
chr7_-_72298752 0.286 NM_001145440
NM_001145441
TYW1B

tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)

chr18_-_24445652 0.225 NM_001650
AQP4
aquaporin 4
chr9_+_21802631 0.219 NM_002451
MTAP
methylthioadenosine phosphorylase
chr2_-_145052059 0.197 NM_001006636
GTDC1
glycosyltransferase-like domain containing 1
chrX_+_153626570 0.183 NM_006013
RPL10
ribosomal protein L10
chr17_-_2614926 0.179 NM_015229
KIAA0664
KIAA0664
chr11_+_32914359 0.178 NM_001076786
QSER1
glutamine and serine rich 1
chr16_+_810764 0.158 NM_005823
NM_001177355
MSLN

mesothelin

chr1_+_11249344 0.125 NM_021146
ANGPTL7
angiopoietin-like 7
chr12_+_10460416 0.096 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr8_-_116681103 0.071 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr7_+_101928390 0.044 NM_020979
SH2B2
SH2B adaptor protein 2
chr19_+_10196757 0.024 NM_018381
C19orf66
chromosome 19 open reading frame 66
chr6_+_31543340 0.017 NM_000594
TNF
tumor necrosis factor
chr19_-_3985460 0.015 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr2_+_166428845 0.001 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.82 1.41e-05 GO:0007267 cell-cell signaling
3.24 5.04e-05 GO:0007154 cell communication
4.38 7.13e-04 GO:0007268 synaptic transmission
3.90 3.20e-03 GO:0019226 transmission of nerve impulse
3.90 3.20e-03 GO:0035637 multicellular organismal signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.98 4.77e-03 GO:0044459 plasma membrane part

Nothing significant found in function category.