Motif ID: CREB1.p2

Z-value: 1.534


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2083948230.591.3e-21Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_17104266 36.214 NM_013354
NM_054026
 CNOT7

CCR4-NOT transcription complex, subunit 7

chr8_-_17104103 34.043 CNOT7
CCR4-NOT transcription complex, subunit 7
chr3_-_49066858 34.033 NM_000884
 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_49066760 33.510 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_49066813 31.594 IMPDH2
IMP (inosine 5'-monophosphate) dehydrogenase 2
chr3_-_156877882 29.235 CCNL1
cyclin L1
chr12_-_123380608 24.120


chr2_-_10588273 23.163 ODC1
ornithine decarboxylase 1
chr3_+_52719935 22.468 NM_014366
NM_206825
NM_206826
 GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr2_-_10588451 22.314 NM_002539
 ODC1
ornithine decarboxylase 1
chr3_+_170075521 19.999 SKIL
SKI-like oncogene
chr3_+_127317271 19.714 MCM2
minichromosome maintenance complex component 2
chr3_+_127317274 19.088 MCM2
minichromosome maintenance complex component 2
chr1_-_245025958 17.991 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr7_+_56019552 17.798 NM_015969
 MRPS17
mitochondrial ribosomal protein S17
chr17_-_685385 17.264 NM_016080
 GLOD4
glyoxalase domain containing 4
chr19_-_40336944 17.119 FBL
fibrillarin
chr19_-_40337018 15.990 NM_001436
 FBL
fibrillarin
chr12_-_76478347 15.969 NAP1L1
nucleosome assembly protein 1-like 1
chr5_+_10353980 15.882



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 119 entries
enrichment   p-value GO term description
5.15 1.13e-02 GO:0006888 ER to Golgi vesicle-mediated transport
5.07 1.56e-10 GO:0051028 mRNA transport
4.95 4.81e-11 GO:0050657 nucleic acid transport
4.95 4.81e-11 GO:0050658 RNA transport
4.95 4.81e-11 GO:0051236 establishment of RNA localization
4.79 1.34e-10 GO:0006403 RNA localization
4.78 2.48e-02 GO:0006369 termination of RNA polymerase II transcription
4.70 1.39e-04 GO:0006405 RNA export from nucleus
4.64 4.18e-04 GO:0031124 mRNA 3'-end processing
4.64 9.91e-04 GO:0006406 mRNA export from nucleus
4.40 7.52e-10 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
4.27 2.70e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
4.27 2.70e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
4.26 1.41e-13 GO:0000375 RNA splicing, via transesterification reactions
4.01 7.93e-04 GO:0051168 nuclear export
3.90 5.24e-03 GO:0031123 RNA 3'-end processing
3.79 7.81e-16 GO:0008380 RNA splicing
3.79 7.56e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
3.58 6.51e-04 GO:0006401 RNA catabolic process
3.53 1.08e-02 GO:0006364 rRNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
9.13 5.33e-05 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
5.04 4.80e-02 GO:0000152 nuclear ubiquitin ligase complex
4.62 2.43e-06 GO:0071013 catalytic step 2 spliceosome
3.95 6.01e-08 GO:0005681 spliceosomal complex
3.32 8.24e-03 GO:0000776 kinetochore
2.89 2.71e-03 GO:0000793 condensed chromosome
2.89 1.12e-02 GO:0016607 nuclear speck
2.80 1.61e-13 GO:0030529 ribonucleoprotein complex
2.70 1.25e-02 GO:0000775 chromosome, centromeric region
2.67 1.57e-04 GO:0016604 nuclear body
2.59 3.48e-02 GO:0031965 nuclear membrane
2.56 5.01e-10 GO:0005730 nucleolus
2.49 7.62e-04 GO:0005635 nuclear envelope
2.44 4.25e-25 GO:0005654 nucleoplasm
2.41 2.40e-02 GO:0005840 ribosome
2.35 2.26e-32 GO:0031981 nuclear lumen
2.34 6.24e-39 GO:0044428 nuclear part
2.27 2.26e-07 GO:0005694 chromosome
2.25 8.98e-06 GO:0044427 chromosomal part
2.15 7.25e-31 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 28 entries
enrichment   p-value GO term description
5.87 6.10e-03 GO:0003727 single-stranded RNA binding
5.15 2.73e-03 GO:0019783 small conjugating protein-specific protease activity
4.70 4.41e-02 GO:0004843 ubiquitin-specific protease activity
3.96 9.24e-03 GO:0004221 ubiquitin thiolesterase activity
3.84 2.62e-02 GO:0003697 single-stranded DNA binding
3.34 1.76e-03 GO:0008026 ATP-dependent helicase activity
3.34 1.76e-03 GO:0070035 purine NTP-dependent helicase activity
2.93 2.83e-03 GO:0004386 helicase activity
2.58 1.12e-17 GO:0003723 RNA binding
2.23 7.28e-04 GO:0016887 ATPase activity
2.17 1.70e-02 GO:0042623 ATPase activity, coupled
1.83 4.77e-02 GO:0016874 ligase activity
1.71 1.94e-12 GO:0000166 nucleotide binding
1.68 1.29e-02 GO:0017111 nucleoside-triphosphatase activity
1.67 1.23e-02 GO:0016462 pyrophosphatase activity
1.67 1.39e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.66 1.58e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.65 6.40e-08 GO:0035639 purine ribonucleoside triphosphate binding
1.64 7.86e-06 GO:0005524 ATP binding
1.62 1.80e-07 GO:0017076 purine nucleotide binding