Motif ID: CRX.p2

Z-value: 0.821


Transcription factors associated with CRX.p2:

Gene SymbolEntrez IDGene Name
CRX 1406 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CRXchr19_+_48325098-0.091.7e-01Click!


Activity profile for motif CRX.p2.

activity profile for motif CRX.p2


Sorted Z-values histogram for motif CRX.p2

Sorted Z-values for motif CRX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CRX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_47655603 8.089 PDZK1IP1
PDZK1 interacting protein 1
chr1_-_47655723 7.557 NM_005764
 PDZK1IP1
PDZK1 interacting protein 1
chr9_-_75567915 7.123 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr8_+_86376130 6.338 NM_000067
 CA2
carbonic anhydrase II
chr12_-_89746244 5.581 NM_001946
NM_022652
 DUSP6

dual specificity phosphatase 6

chr14_-_61748510 5.166 NM_001017970
 TMEM30B
transmembrane protein 30B
chr4_+_88896868 4.980 SPP1
secreted phosphoprotein 1
chr4_+_88896838 4.925 SPP1
secreted phosphoprotein 1
chr4_+_88896899 4.819 SPP1
secreted phosphoprotein 1
chr12_-_89746238 4.777 DUSP6
dual specificity phosphatase 6
chr2_-_20251788 4.695 NM_014713
 LAPTM4A
lysosomal protein transmembrane 4 alpha
chr17_-_39092714 4.465 KRT23
keratin 23 (histone deacetylase inducible)
chr17_+_68100994 4.403 NM_170742
 KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr14_-_61747956 4.398 TMEM30B
transmembrane protein 30B
chr3_+_149192367 4.377 NM_004617
 TM4SF4
transmembrane 4 L six family member 4
chr16_+_31539202 4.150 NM_016633
 AHSP
alpha hemoglobin stabilizing protein
chr8_-_80993009 3.847 NM_001025252
 TPD52
tumor protein D52
chr21_-_43187265 3.811 RIPK4
receptor-interacting serine-threonine kinase 4
chr3_+_122044010 3.618 NM_005213
 CSTA
cystatin A (stefin A)
chr9_-_104198045 3.555 NM_000035
 ALDOB
aldolase B, fructose-bisphosphate

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
4.49 2.05e-02 GO:0006690 icosanoid metabolic process
4.23 3.95e-02 GO:0033559 unsaturated fatty acid metabolic process
2.82 2.18e-02 GO:0042445 hormone metabolic process
2.48 1.83e-02 GO:0006631 fatty acid metabolic process
2.25 1.04e-02 GO:0032787 monocarboxylic acid metabolic process
1.94 2.28e-04 GO:0006082 organic acid metabolic process
1.87 2.02e-03 GO:0019752 carboxylic acid metabolic process
1.87 2.02e-03 GO:0043436 oxoacid metabolic process
1.83 4.30e-03 GO:0042180 cellular ketone metabolic process
1.65 9.33e-04 GO:0002376 immune system process
1.41 1.02e-02 GO:0042221 response to chemical stimulus
1.39 3.04e-02 GO:0065008 regulation of biological quality
1.27 1.39e-02 GO:0051716 cellular response to stimulus
1.23 1.11e-05 GO:0008152 metabolic process
1.21 3.59e-03 GO:0044238 primary metabolic process
1.20 1.17e-02 GO:0050896 response to stimulus
1.19 2.48e-02 GO:0044237 cellular metabolic process
1.16 8.39e-08 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.75 9.93e-04 GO:0005615 extracellular space
1.65 8.36e-04 GO:0044421 extracellular region part
1.63 1.33e-02 GO:0005626 insoluble fraction
1.58 4.88e-02 GO:0005624 membrane fraction
1.52 1.99e-02 GO:0000267 cell fraction
1.44 5.84e-04 GO:0005576 extracellular region
1.37 9.25e-03 GO:0044459 plasma membrane part
1.34 4.48e-02 GO:0005829 cytosol
1.19 4.57e-03 GO:0044444 cytoplasmic part
1.14 1.61e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
14.67 2.36e-02 GO:0032052 bile acid binding
5.24 4.95e-02 GO:0016229 steroid dehydrogenase activity
4.00 1.78e-02 GO:0042562 hormone binding
1.98 5.25e-03 GO:0008289 lipid binding
1.17 3.76e-03 GO:0005515 protein binding