Motif ID: EBF1.p2

Z-value: 1.604


Transcription factors associated with EBF1.p2:

Gene SymbolEntrez IDGene Name
EBF1 1879 early B-cell factor 1



Activity profile for motif EBF1.p2.

activity profile for motif EBF1.p2


Sorted Z-values histogram for motif EBF1.p2

Sorted Z-values for motif EBF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EBF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_170102098 48.115 NM_001202550
NM_182552
WDR27

WD repeat domain 27

chr11_+_73359734 24.647 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_-_117747331 24.072 FXYD6
FXYD domain containing ion transport regulator 6
chr11_-_117747618 20.071 NM_001204268
NM_001243598
NM_001164832
NM_001164836
NM_001164837
NM_022003
FXYD6-FXYD2

FXYD6



FXYD6-FXYD2 readthrough

FXYD domain containing ion transport regulator 6



chr8_-_22089517 19.836 PHYHIP
phytanoyl-CoA 2-hydroxylase interacting protein
chr2_+_17935379 18.749 NM_001130009
GEN1
Gen endonuclease homolog 1 (Drosophila)
chr8_-_22089850 18.419 NM_001099335
NM_014759
PHYHIP

phytanoyl-CoA 2-hydroxylase interacting protein

chr4_+_4388804 17.541 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr16_+_22825481 17.361 HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr4_+_128651518 17.324 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr1_+_2005424 17.294 NM_001242874
PRKCZ
protein kinase C, zeta
chr4_+_4388717 17.212 D4S234E
DNA segment on chromosome 4 (unique) 234 expressed sequence
chr16_+_58498216 16.921 NDRG4
NDRG family member 4
chr14_+_92790151 16.597 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr19_+_50936159 16.133 NM_004533
MYBPC2
myosin binding protein C, fast type
chr16_+_58534045 16.101 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr13_-_30881556 14.715 NM_032116
KATNAL1
katanin p60 subunit A-like 1
chr1_+_152647770 14.586 NM_178429
LCE2C
late cornified envelope 2C
chr16_-_19896105 14.537 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr8_-_33424642 14.049 NM_024787
RNF122
ring finger protein 122

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
2.78 2.53e-02 GO:0007269 neurotransmitter secretion
2.37 1.96e-02 GO:0006836 neurotransmitter transport
1.86 1.23e-05 GO:0007268 synaptic transmission
1.76 1.30e-02 GO:0044057 regulation of system process
1.75 1.11e-04 GO:0019226 transmission of nerve impulse
1.75 1.11e-04 GO:0035637 multicellular organismal signaling
1.58 1.91e-04 GO:0007267 cell-cell signaling
1.51 1.23e-03 GO:0040011 locomotion
1.47 9.61e-04 GO:0007154 cell communication
1.42 1.11e-06 GO:0007166 cell surface receptor linked signaling pathway
1.41 1.56e-08 GO:0042221 response to chemical stimulus
1.39 1.63e-15 GO:0023052 signaling
1.38 1.52e-04 GO:0023051 regulation of signaling
1.38 1.57e-03 GO:0009966 regulation of signal transduction
1.37 4.22e-05 GO:0048583 regulation of response to stimulus
1.36 4.16e-11 GO:0007165 signal transduction
1.36 2.64e-02 GO:0010033 response to organic substance
1.31 5.91e-11 GO:0051716 cellular response to stimulus
1.29 3.05e-03 GO:0065008 regulation of biological quality
1.23 1.88e-10 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
4.77 3.09e-02 GO:0042613 MHC class II protein complex
3.04 1.27e-02 GO:0030173 integral to Golgi membrane
2.84 3.23e-02 GO:0031228 intrinsic to Golgi membrane
2.74 4.78e-03 GO:0031256 leading edge membrane
2.10 1.45e-02 GO:0031253 cell projection membrane
2.06 1.81e-02 GO:0031301 integral to organelle membrane
2.05 3.23e-04 GO:0030141 stored secretory granule
1.98 1.54e-02 GO:0031300 intrinsic to organelle membrane
1.82 8.26e-03 GO:0016323 basolateral plasma membrane
1.51 4.42e-02 GO:0000139 Golgi membrane
1.49 1.29e-02 GO:0030054 cell junction
1.48 3.05e-13 GO:0044459 plasma membrane part
1.47 1.57e-06 GO:0031226 intrinsic to plasma membrane
1.47 2.38e-06 GO:0005887 integral to plasma membrane
1.39 1.42e-03 GO:0000267 cell fraction
1.19 4.28e-04 GO:0005886 plasma membrane
1.19 4.44e-04 GO:0071944 cell periphery
1.12 1.94e-02 GO:0044425 membrane part
1.10 2.93e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.34 5.51e-03 GO:0003823 antigen binding
2.29 4.07e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
2.26 1.52e-04 GO:0005085 guanyl-nucleotide exchange factor activity
2.07 4.78e-02 GO:0015276 ligand-gated ion channel activity
2.07 4.78e-02 GO:0022834 ligand-gated channel activity
1.77 1.18e-02 GO:0005261 cation channel activity
1.74 2.64e-04 GO:0015267 channel activity
1.73 2.95e-04 GO:0022803 passive transmembrane transporter activity
1.68 2.14e-03 GO:0022838 substrate-specific channel activity
1.67 4.27e-03 GO:0005216 ion channel activity
1.66 4.16e-02 GO:0022836 gated channel activity
1.54 3.59e-02 GO:0030695 GTPase regulator activity
1.43 2.61e-03 GO:0022857 transmembrane transporter activity
1.39 3.32e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.35 1.19e-02 GO:0005215 transporter activity
1.35 4.65e-02 GO:0022892 substrate-specific transporter activity
1.11 2.60e-02 GO:0005515 protein binding
1.08 5.06e-05 GO:0005488 binding