Motif ID: EHF.p2

Z-value: 3.273


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_34642587,
chr11_+_34654010		-0.027.2e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_203830723 90.557 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_+_203830732 87.440 NM_003094
 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_+_32688013 82.817 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32687970 82.531 NM_003757
 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_203830763 81.657 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr1_+_32688053 80.942 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32688010 80.058 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr12_-_110888079 78.743 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_-_110888106 77.080 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_-_110888098 71.099 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr12_-_110888160 66.967 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr1_+_84944919 66.787 NM_025065
 RPF1
ribosome production factor 1 homolog (S. cerevisiae)
chr2_-_230786618 66.754 NM_004238
 TRIP12
thyroid hormone receptor interactor 12
chr11_+_65769956 63.571 BANF1
barrier to autointegration factor 1
chr10_+_12238208 63.203 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr7_+_141438122 63.178 NM_003143
 SSBP1
single-stranded DNA binding protein 1
chr12_-_110888134 61.313 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr20_-_2451355 59.893 SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr11_+_65769886 58.757 BANF1
barrier to autointegration factor 1
chr5_-_140070888 57.848 HARS
histidyl-tRNA synthetase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 256 entries
enrichment   p-value GO term description
6.80 2.20e-02 GO:0048194 Golgi vesicle budding
6.80 2.20e-02 GO:0048200 Golgi transport vesicle coating
6.80 2.20e-02 GO:0048205 COPI coating of Golgi vesicle
5.24 7.62e-04 GO:0048199 vesicle targeting, to, from or within Golgi
4.73 1.23e-03 GO:0006901 vesicle coating
4.54 2.29e-03 GO:0006900 membrane budding
4.37 5.86e-06 GO:0006413 translational initiation
4.37 6.25e-04 GO:0006903 vesicle targeting
4.37 6.25e-04 GO:0009452 RNA capping
4.22 2.76e-03 GO:0006370 mRNA capping
4.12 2.84e-07 GO:0006521 regulation of cellular amino acid metabolic process
4.10 1.81e-06 GO:0050434 positive regulation of viral transcription
4.08 4.63e-03 GO:0000387 spliceosomal snRNP assembly
3.97 7.70e-07 GO:0046782 regulation of viral transcription
3.96 3.17e-08 GO:0071158 positive regulation of cell cycle arrest
3.87 3.17e-07 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.87 3.17e-07 GO:0072395 signal transduction involved in cell cycle checkpoint
3.87 3.17e-07 GO:0072401 signal transduction involved in DNA integrity checkpoint
3.87 3.17e-07 GO:0072404 signal transduction involved in G1/S transition checkpoint
3.87 3.17e-07 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 69 entries
enrichment   p-value GO term description
6.05 8.69e-04 GO:0005852 eukaryotic translation initiation factor 3 complex
4.51 2.61e-05 GO:0030532 small nuclear ribonucleoprotein complex
4.37 3.45e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.16 5.31e-10 GO:0000502 proteasome complex
3.78 5.69e-04 GO:0022625 cytosolic large ribosomal subunit
3.65 3.68e-09 GO:0071013 catalytic step 2 spliceosome
3.55 1.34e-02 GO:0030660 Golgi-associated vesicle membrane
3.44 1.12e-05 GO:0015934 large ribosomal subunit
3.33 7.12e-13 GO:0005681 spliceosomal complex
3.18 8.39e-03 GO:0015030 Cajal body
3.14 3.36e-02 GO:0030120 vesicle coat
3.07 4.47e-05 GO:0022626 cytosolic ribosome
3.07 2.39e-03 GO:0005798 Golgi-associated vesicle
2.91 1.22e-03 GO:0030117 membrane coat
2.91 1.22e-03 GO:0048475 coated membrane
2.79 6.70e-32 GO:0030529 ribonucleoprotein complex
2.69 5.34e-06 GO:0016607 nuclear speck
2.67 3.82e-02 GO:0030496 midbody
2.54 4.03e-08 GO:0005840 ribosome
2.41 1.98e-05 GO:0044445 cytosolic part

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
3.82 1.37e-05 GO:0003743 translation initiation factor activity
3.38 2.61e-03 GO:0004812 aminoacyl-tRNA ligase activity
3.38 2.61e-03 GO:0016875 ligase activity, forming carbon-oxygen bonds
3.38 2.61e-03 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
3.24 1.63e-06 GO:0008135 translation factor activity, nucleic acid binding
2.62 9.38e-07 GO:0003735 structural constituent of ribosome
2.27 1.21e-27 GO:0003723 RNA binding
1.72 6.55e-03 GO:0016887 ATPase activity
1.65 2.53e-03 GO:0016874 ligase activity
1.64 3.93e-06 GO:0017111 nucleoside-triphosphatase activity
1.63 2.69e-06 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.62 3.52e-06 GO:0016817 hydrolase activity, acting on acid anhydrides
1.62 3.80e-06 GO:0016462 pyrophosphatase activity
1.43 1.17e-10 GO:0000166 nucleotide binding
1.42 1.57e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.41 1.08e-50 GO:0005515 protein binding
1.40 5.87e-07 GO:0032553 ribonucleotide binding
1.40 5.87e-07 GO:0032555 purine ribonucleotide binding
1.40 6.82e-07 GO:0017076 purine nucleotide binding
1.38 1.22e-04 GO:0005524 ATP binding