Motif ID: ELF1,2,4.p2

Z-value: 4.580


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF4chrX_-_129244471,
chrX_-_129244652		0.714.8e-35Click!
ELF1chr13_-_416350720.516.7e-16Click!
ELF2chr4_-_1400606010.322.0e-06Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_119738542 100.401 NM_001137554
 MCTS1
malignant T cell amplified sequence 1
chrX_+_119737984 95.119 MCTS1
malignant T cell amplified sequence 1
chr9_-_35103144 86.792 NM_013442
 STOML2
stomatin (EPB72)-like 2
chr2_-_73964427 85.558 NM_016058
 TPRKB
TP53RK binding protein
chr11_-_67169309 85.058 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr1_+_32688053 80.690 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32687970 77.001 NM_003757
 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr1_+_32688013 76.244 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr17_-_4851688 75.897 PFN1
profilin 1
chr1_+_32688010 73.493 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr11_-_67169340 73.113 NM_001008709
NM_002708
NM_206873
 PPP1CA


protein phosphatase 1, catalytic subunit, alpha isozyme


chr12_-_110888134 72.045 ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_-_67169252 71.886 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_-_230786618 71.265 NM_004238
 TRIP12
thyroid hormone receptor interactor 12
chr3_-_32544319 68.575 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chrX_-_153775427 67.661 G6PD
glucose-6-phosphate dehydrogenase
chr1_+_203830763 66.741 SNRPE
small nuclear ribonucleoprotein polypeptide E
chr12_+_7080077 66.702 EMG1
EMG1 nucleolar protein homolog (S. cerevisiae)
chr1_+_110091218 65.219 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr12_+_69979202 64.567 NM_006431
 CCT2
chaperonin containing TCP1, subunit 2 (beta)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 329 entries
enrichment   p-value GO term description
5.15 4.51e-02 GO:0045136 development of secondary sexual characteristics
4.36 3.40e-03 GO:0042255 ribosome assembly
3.87 1.04e-02 GO:0042274 ribosomal small subunit biogenesis
3.64 2.89e-02 GO:0070972 protein localization in endoplasmic reticulum
3.48 2.13e-07 GO:0006413 translational initiation
3.35 4.71e-02 GO:0048199 vesicle targeting, to, from or within Golgi
3.29 4.50e-15 GO:0019080 viral genome expression
3.29 4.50e-15 GO:0019083 viral transcription
3.26 7.62e-04 GO:0006903 vesicle targeting
3.24 6.53e-15 GO:0006415 translational termination
3.24 2.46e-13 GO:0000216 M/G1 transition of mitotic cell cycle
3.09 7.12e-12 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.09 5.12e-03 GO:0000387 spliceosomal snRNP assembly
3.09 5.12e-03 GO:0009452 RNA capping
3.09 4.06e-02 GO:0006900 membrane budding
3.08 2.02e-09 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.07 5.35e-05 GO:0006369 termination of RNA polymerase II transcription
3.05 2.05e-14 GO:0006414 translational elongation
3.05 8.22e-10 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.04 9.95e-14 GO:0043241 protein complex disassembly

Gene overrepresentation in compartment category:

Showing 1 to 20 of 83 entries
enrichment   p-value GO term description
4.36 5.38e-04 GO:0005852 eukaryotic translation initiation factor 3 complex
3.49 8.75e-07 GO:0022627 cytosolic small ribosomal subunit
3.32 3.61e-05 GO:0030532 small nuclear ribonucleoprotein complex
3.06 2.68e-11 GO:0022626 cytosolic ribosome
2.94 1.21e-10 GO:0071013 catalytic step 2 spliceosome
2.93 3.83e-04 GO:0022625 cytosolic large ribosomal subunit
2.86 1.51e-07 GO:0000502 proteasome complex
2.72 4.15e-05 GO:0015935 small ribosomal subunit
2.69 1.41e-14 GO:0005681 spliceosomal complex
2.62 2.71e-05 GO:0015934 large ribosomal subunit
2.52 1.94e-16 GO:0005840 ribosome
2.45 7.42e-04 GO:0030496 midbody
2.40 1.70e-40 GO:0030529 ribonucleoprotein complex
2.39 2.50e-04 GO:0005643 nuclear pore
2.27 2.42e-09 GO:0044445 cytosolic part
2.24 3.73e-04 GO:0046930 pore complex
2.24 8.65e-03 GO:0016363 nuclear matrix
2.20 6.87e-03 GO:0034399 nuclear periphery
2.16 5.36e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.15 8.50e-03 GO:0000777 condensed chromosome kinetochore

Gene overrepresentation in function category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
3.01 3.51e-06 GO:0003743 translation initiation factor activity
2.86 6.72e-10 GO:0008135 translation factor activity, nucleic acid binding
2.64 9.52e-03 GO:0032182 small conjugating protein binding
2.59 4.21e-14 GO:0003735 structural constituent of ribosome
2.51 2.48e-02 GO:0043021 ribonucleoprotein binding
2.46 2.38e-02 GO:0004812 aminoacyl-tRNA ligase activity
2.46 2.38e-02 GO:0016875 ligase activity, forming carbon-oxygen bonds
2.46 2.38e-02 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
2.13 2.38e-03 GO:0035257 nuclear hormone receptor binding
2.09 1.46e-02 GO:0031625 ubiquitin protein ligase binding
2.05 3.90e-38 GO:0003723 RNA binding
2.03 3.92e-03 GO:0051427 hormone receptor binding
2.01 1.39e-03 GO:0051082 unfolded protein binding
1.68 6.33e-03 GO:0003924 GTPase activity
1.64 1.10e-02 GO:0003713 transcription coactivator activity
1.59 1.55e-04 GO:0003712 transcription cofactor activity
1.58 1.81e-04 GO:0000988 protein binding transcription factor activity
1.58 1.81e-04 GO:0000989 transcription factor binding transcription factor activity
1.50 2.40e-07 GO:0019899 enzyme binding
1.44 1.60e-02 GO:0019904 protein domain specific binding