Motif ID: EOMES.p2

Z-value: 1.023


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin



Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_5271035 19.971 NM_000559
 HBG1
hemoglobin, gamma A
chr14_+_95078713 16.397 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr11_-_33913835 13.814 NM_005574
 LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_114135965 13.271 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_112041253 12.073 NM_153047
 FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_157189040 12.053 NM_006186
 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_69742130 10.687 NM_000239
 LYZ
lysozyme
chr1_+_55464605 10.001 NM_057176
 BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr12_+_69742140 9.991 LYZ
lysozyme
chr17_+_25958257 9.781 LGALS9
lectin, galactoside-binding, soluble, 9
chr4_-_186732208 9.587 NM_001145671
 SORBS2
sorbin and SH3 domain containing 2
chr17_+_25958217 9.522 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_-_89746238 9.352 DUSP6
dual specificity phosphatase 6
chr12_-_89745997 9.314 DUSP6
dual specificity phosphatase 6
chr12_-_89746244 9.240 NM_001946
NM_022652
 DUSP6

dual specificity phosphatase 6

chr17_+_25958245 9.164 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 8.542 NM_002308
NM_009587
 LGALS9

lectin, galactoside-binding, soluble, 9

chr17_+_25958192 8.426 LGALS9
lectin, galactoside-binding, soluble, 9
chr10_+_114135937 8.354 NM_016234
 ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_-_131132642 8.325 FNIP1
folliculin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 84 entries
enrichment   p-value GO term description
14.17 1.06e-02 GO:0002456 T cell mediated immunity
3.89 5.99e-03 GO:0016049 cell growth
3.70 2.39e-02 GO:0050708 regulation of protein secretion
3.54 4.12e-02 GO:0022612 gland morphogenesis
3.48 1.45e-02 GO:0030879 mammary gland development
3.14 2.10e-02 GO:0061138 morphogenesis of a branching epithelium
3.07 6.12e-03 GO:0001763 morphogenesis of a branching structure
2.76 1.50e-02 GO:0050900 leukocyte migration
2.74 2.69e-02 GO:0042445 hormone metabolic process
2.63 6.71e-03 GO:0048732 gland development
2.47 1.83e-03 GO:0008361 regulation of cell size
2.46 3.73e-02 GO:0010817 regulation of hormone levels
2.35 8.63e-06 GO:0007268 synaptic transmission
2.28 1.78e-10 GO:0007267 cell-cell signaling
2.28 5.09e-06 GO:0019226 transmission of nerve impulse
2.28 5.09e-06 GO:0035637 multicellular organismal signaling
2.20 6.14e-03 GO:0044057 regulation of system process
2.19 2.30e-03 GO:0090066 regulation of anatomical structure size
2.19 1.23e-02 GO:0051046 regulation of secretion
2.17 1.20e-02 GO:0032535 regulation of cellular component size

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
2.55 7.97e-04 GO:0030141 stored secretory granule
2.29 1.34e-02 GO:0034702 ion channel complex
2.19 1.32e-04 GO:0009986 cell surface
2.15 3.03e-02 GO:0016323 basolateral plasma membrane
1.97 4.98e-12 GO:0005887 integral to plasma membrane
1.93 2.14e-11 GO:0031226 intrinsic to plasma membrane
1.90 4.77e-06 GO:0005615 extracellular space
1.76 5.13e-04 GO:0031410 cytoplasmic vesicle
1.74 4.69e-04 GO:0031982 vesicle
1.74 1.54e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.73 1.55e-03 GO:0031988 membrane-bounded vesicle
1.72 3.52e-13 GO:0044459 plasma membrane part
1.72 2.84e-05 GO:0044421 extracellular region part
1.62 9.98e-03 GO:0005626 insoluble fraction
1.60 1.91e-02 GO:0005624 membrane fraction
1.54 9.10e-07 GO:0005576 extracellular region
1.53 1.03e-02 GO:0000267 cell fraction
1.38 1.99e-08 GO:0005886 plasma membrane
1.37 7.06e-08 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
5.67 2.86e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
4.10 7.07e-03 GO:0004879 ligand-dependent nuclear receptor activity
4.07 3.58e-02 GO:0001948 glycoprotein binding
4.00 1.97e-02 GO:0003707 steroid hormone receptor activity
3.36 5.85e-03 GO:0015294 solute:cation symporter activity
2.86 7.95e-03 GO:0015276 ligand-gated ion channel activity
2.86 7.95e-03 GO:0022834 ligand-gated channel activity
2.39 7.73e-07 GO:0015267 channel activity
2.38 8.49e-07 GO:0022803 passive transmembrane transporter activity
2.37 1.09e-04 GO:0022836 gated channel activity
2.29 1.36e-05 GO:0022838 substrate-specific channel activity
2.23 5.42e-05 GO:0005216 ion channel activity
2.19 9.43e-03 GO:0005261 cation channel activity
1.96 4.33e-03 GO:0008289 lipid binding
1.94 3.67e-04 GO:0008324 cation transmembrane transporter activity
1.88 2.46e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.88 3.35e-05 GO:0015075 ion transmembrane transporter activity
1.85 3.57e-07 GO:0005102 receptor binding
1.84 2.84e-06 GO:0022857 transmembrane transporter activity
1.74 3.17e-05 GO:0022892 substrate-specific transporter activity