Motif ID: EOMES.p2

Z-value: 1.023


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin



Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_5271035 19.971 NM_000559
HBG1
hemoglobin, gamma A
chr14_+_95078713 16.397 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr11_-_33913835 13.814 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr10_+_114135965 13.271 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_112041253 12.073 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_157189040 12.053 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr12_+_69742130 10.687 NM_000239
LYZ
lysozyme
chr1_+_55464605 10.001 NM_057176
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr12_+_69742140 9.991 LYZ
lysozyme
chr17_+_25958257 9.781 LGALS9
lectin, galactoside-binding, soluble, 9
chr4_-_186732208 9.587 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr17_+_25958217 9.522 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_-_89746238 9.352 DUSP6
dual specificity phosphatase 6
chr12_-_89745997 9.314 DUSP6
dual specificity phosphatase 6
chr12_-_89746244 9.240 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr17_+_25958245 9.164 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 8.542 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr17_+_25958192 8.426 LGALS9
lectin, galactoside-binding, soluble, 9
chr10_+_114135937 8.354 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_-_131132642 8.325 FNIP1
folliculin interacting protein 1
chr5_-_39270708 8.171 NM_001243093
FYB
FYN binding protein
chr16_+_77233348 8.163 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr4_-_186732047 7.952 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr11_-_5275904 7.481 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr10_+_114136014 7.472 ACSL5
acyl-CoA synthetase long-chain family member 5
chr4_-_57547845 7.437 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr2_+_219246751 7.328 NM_000578
SLC11A1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr5_+_54320083 7.327 NM_002104
GZMK
granzyme K (granzyme 3; tryptase II)
chr8_-_120651019 7.166 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr9_+_17134974 7.154 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr7_-_36764000 7.094 NM_001177506
NM_001177507
NM_001637
AOAH


acyloxyacyl hydrolase (neutrophil)


chr4_+_160188997 7.079 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_145438437 7.045 NM_006472
TXNIP
thioredoxin interacting protein
chr1_-_156786500 6.875 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr3_-_49459870 6.747 AMT
aminomethyltransferase
chr19_-_36236291 6.384 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr10_+_70847817 6.339 NM_002727
SRGN
serglycin
chr6_+_99872769 6.331


chr8_-_146202727 6.262 ZNF252
zinc finger protein 252
chr21_-_46340821 6.115 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_34043234 6.043 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr3_-_133748727 6.042 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chrX_+_70443055 6.030 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr16_+_30386097 6.000 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr21_-_46340776 5.999 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr12_-_6233684 5.876 NM_000552
VWF
von Willebrand factor
chr15_+_74421986 5.816 NM_001130137
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr1_+_182758871 5.803 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr1_-_11907741 5.707 NM_006172
NPPA
natriuretic peptide A
chr8_+_1993157 5.498 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr17_+_8213555 5.496 NM_173728
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr14_-_107013474 5.418 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_131894343 5.371 NM_000045
NM_001244438
ARG1

arginase, liver

chr10_+_70847857 5.370 SRGN
serglycin
chr4_-_186578122 5.345 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr7_+_150264457 5.345 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr3_-_187463474 5.253 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr17_-_42345434 5.250 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr14_-_107113943 5.230 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_133748828 5.070 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr5_+_148206155 5.055 NM_000024
ADRB2
adrenergic, beta-2-, receptor, surface
chr1_-_116311161 5.048 CASQ2
calsequestrin 2 (cardiac muscle)
chr14_+_21467413 4.988 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr8_-_11705259 4.940


chr4_-_186577858 4.900 SORBS2
sorbin and SH3 domain containing 2
chr6_-_32497925 4.803 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr17_+_18380097 4.652 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr14_-_24036532 4.650 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr17_-_56406120 4.639 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chr11_+_73358593 4.638 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr4_+_124317884 4.594 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr5_+_35856990 4.575 NM_002185
IL7R
interleukin 7 receptor
chr12_-_45269953 4.427 NELL2
NEL-like 2 (chicken)
chr19_+_14017038 4.395 CC2D1A
coiled-coil and C2 domain containing 1A
chr1_+_38022514 4.385 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr19_+_47813074 4.356 NM_001736
C5AR1
complement component 5a receptor 1
chr9_+_102584136 4.336 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr3_+_38347426 4.331 NM_004803
SLC22A14
solute carrier family 22, member 14
chr10_+_114135013 4.253 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_212781969 4.224 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr6_+_39760148 4.214 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_10452939 4.166 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chrX_-_107018889 4.156 TSC22D3
TSC22 domain family, member 3
chr3_+_137728949 4.134 NM_016369
CLDN18
claudin 18
chr17_+_8339135 4.110 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr17_+_8214139 4.097 NM_025014
ARHGEF15
Rho guanine nucleotide exchange factor (GEF) 15
chr17_-_61973870 4.081 NM_001317
CSH1
chorionic somatomammotropin hormone 1 (placental lactogen)
chr5_+_156820161 4.035 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr19_-_14016908 4.015 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr16_+_57702156 4.011 NM_170776
GPR97
G protein-coupled receptor 97
chr3_-_195310985 3.969 NM_001647
APOD
apolipoprotein D
chr17_-_61996135 3.954 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chrX_-_15873094 3.932 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_55034633 3.887 SAMD4A
sterile alpha motif domain containing 4A
chrX_+_69642880 3.884 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr10_+_135051407 3.881 NM_014468
VENTX
VENT homeobox
chr19_-_1020995 3.880 C19orf6
chromosome 19 open reading frame 6
chr1_-_44482996 3.826 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr5_-_1882764 3.816 NM_016358
IRX4
iroquois homeobox 4
chr9_-_79520878 3.801 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr6_-_13487772 3.769 NM_001242629
NM_018988
GFOD1

glucose-fructose oxidoreductase domain containing 1

chr14_-_76447445 3.762 TGFB3
transforming growth factor, beta 3
chr7_-_150652861 3.745 NM_001204798
NM_172057
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr6_+_32132379 3.734 NM_030652
EGFL8
EGF-like-domain, multiple 8
chr6_-_46459710 3.691 NM_001251973
RCAN2
regulator of calcineurin 2
chr8_-_67090690 3.683 NM_000756
CRH
corticotropin releasing hormone
chr1_+_153600859 3.595 NM_006271
S100A1
S100 calcium binding protein A1
chr18_-_24442534 3.566 NM_004028
AQP4
aquaporin 4
chr1_+_212782103 3.551 ATF3
activating transcription factor 3
chr19_+_47524142 3.545 NM_002517
NPAS1
neuronal PAS domain protein 1
chr17_-_20370819 3.508 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr11_+_63606598 3.497 MARK2
MAP/microtubule affinity-regulating kinase 2
chrX_+_37639306 3.492 CYBB
cytochrome b-245, beta polypeptide
chr14_+_21249209 3.489 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr10_-_72362441 3.483 PRF1
perforin 1 (pore forming protein)
chr12_-_111358353 3.464 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr3_+_10857867 3.458 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr5_+_113698304 3.441 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr2_-_183731279 3.415 NM_001463
FRZB
frizzled-related protein
chr14_-_106174914 3.401 IGHA1
immunoglobulin heavy constant alpha 1
chr18_+_72922725 3.387 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr20_-_23062786 3.380 CD93
CD93 molecule
chr17_-_61950997 3.322 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr6_-_46293628 3.318 NM_005822
RCAN2
regulator of calcineurin 2
chr1_+_150230168 3.316 NM_012113
CA14
carbonic anhydrase XIV
chr17_+_56315786 3.291 NM_001160102
NM_006151
LPO

lactoperoxidase

chr2_+_219724545 3.284 NM_006522
WNT6
wingless-type MMTV integration site family, member 6
chr3_-_12941547 3.272 IQSEC1
IQ motif and Sec7 domain 1
chr14_-_24036939 3.253 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr1_+_45266048 3.242 PLK3
polo-like kinase 3
chr11_+_45907198 3.226 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr19_+_48867650 3.196 NM_012451
SYNGR4
synaptogyrin 4
chr6_-_97731051 3.194 NM_198468
MMS22L
MMS22-like, DNA repair protein
chr3_-_187463227 3.176 BCL6
B-cell CLL/lymphoma 6
chr10_+_11047274 3.160 CELF2
CUGBP, Elav-like family member 2
chr14_+_24584009 3.142 DCAF11
DDB1 and CUL4 associated factor 11
chr1_+_174769034 3.135 NM_001243765
RABGAP1L
RAB GTPase activating protein 1-like
chr20_+_17207669 3.119 PCSK2
proprotein convertase subtilisin/kexin type 2
chr16_+_2587989 3.115 PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_+_27282163 3.025 NM_001989
EVX1
even-skipped homeobox 1
chr5_-_112630557 3.009 NM_002387
MCC
mutated in colorectal cancers
chr11_-_114466397 2.998 FAM55D
family with sequence similarity 55, member D
chr14_+_24583979 2.974 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_240775388 2.972 GREM2
gremlin 2
chr10_-_126432893 2.965 NM_014661
FAM53B
family with sequence similarity 53, member B
chr14_-_106774311 2.961 IGHA1
immunoglobulin heavy constant alpha 1
chr2_-_197036262 2.943 STK17B
serine/threonine kinase 17b
chrX_+_152770083 2.918 BGN
biglycan
chrX_+_16804531 2.883 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr10_+_11047253 2.877 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr7_+_5920426 2.870 NM_001097622
OCM
oncomodulin
chr17_-_61988614 2.852 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chrX_-_135749436 2.845 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr16_+_1583657 2.823 TMEM204
transmembrane protein 204
chr6_+_42788793 2.813 NM_015349
KIAA0240
KIAA0240
chr12_+_54943176 2.792 NM_000924
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr15_-_35087748 2.790 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr3_+_50654868 2.786 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chrX_-_107019001 2.784 NM_198057
TSC22D3
TSC22 domain family, member 3
chr1_+_150245182 2.736 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr19_+_55591759 2.699 NM_017729
EPS8L1
EPS8-like 1
chr1_+_27114409 2.699 NM_017837
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr14_-_106110894 2.697 IGHG2
immunoglobulin heavy constant gamma 2 (G2m marker)
chr21_+_40823779 2.693 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr17_+_38230678 2.691 THRA
thyroid hormone receptor, alpha
chr8_-_82395401 2.663 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr19_-_46285746 2.662 DMPK
dystrophia myotonica-protein kinase
chr7_-_64023444 2.656


chr2_-_25468909 2.650 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr20_+_55904814 2.643 NM_012444
NM_198265
SPO11

SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)

chr1_-_46598250 2.633 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr3_+_52811601 2.628 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr19_-_39390168 2.623 NM_012237
NM_001193286
NM_030593
SIRT2


sirtuin 2


chr1_-_169555624 2.621 F5
coagulation factor V (proaccelerin, labile factor)
chr5_+_74807580 2.597 NM_016218
POLK
polymerase (DNA directed) kappa
chr12_-_45270071 2.596 NELL2
NEL-like 2 (chicken)
chr10_+_118305427 2.593 NM_000936
PNLIP
pancreatic lipase
chr1_+_203444955 2.569 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr16_-_18937722 2.557 NM_015092
SMG1
smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr1_+_151584514 2.555 NM_030918
SNX27
sorting nexin family member 27
chr16_+_72097124 2.555 NM_020995
HPR
haptoglobin-related protein
chr1_-_12677347 2.548 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_-_156399183 2.546 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr19_+_50713823 2.534 MYH14
myosin, heavy chain 14, non-muscle
chr9_-_117267710 2.515 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chr2_+_16081945 2.510 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_-_46505077 2.494 NM_001199149
LTF
lactotransferrin
chr14_-_23288912 2.486 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_25799024 2.482 NM_014238
KSR1
kinase suppressor of ras 1
chr15_-_58357848 2.481 ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr16_+_2653350 2.455 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr17_+_34640030 2.447 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr7_-_99766191 2.447 GAL3ST4
galactose-3-O-sulfotransferase 4
chr1_+_28199053 2.389 NM_001039477
NM_001105556
NM_004848
C1orf38


chromosome 1 open reading frame 38


chr10_-_123356158 2.387 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr11_-_46408105 2.381 NM_000741
CHRM4
cholinergic receptor, muscarinic 4
chr12_+_54943358 2.366 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr1_+_17846818 2.337 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_31271277 2.317 NM_000632
NM_001145808
ITGAM

integrin, alpha M (complement component 3 receptor 3 subunit)

chr11_-_62521533 2.315 NM_024784
ZBTB3
zinc finger and BTB domain containing 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.57 4.95e-15 GO:0023052 signaling
1.43 8.93e-14 GO:0032501 multicellular organismal process
1.76 6.53e-13 GO:0065008 regulation of biological quality
1.35 1.12e-11 GO:0050896 response to stimulus
1.28 1.33e-11 GO:0065007 biological regulation
2.09 1.14e-10 GO:0007154 cell communication
2.28 1.78e-10 GO:0007267 cell-cell signaling
1.49 3.54e-09 GO:0007165 signal transduction
1.16 4.74e-09 GO:0009987 cellular process
1.41 1.62e-08 GO:0051716 cellular response to stimulus
1.42 9.99e-08 GO:0032502 developmental process
1.65 3.16e-07 GO:0007166 cell surface receptor linked signaling pathway
1.42 9.42e-07 GO:0007275 multicellular organismal development
1.94 1.16e-06 GO:0009611 response to wounding
1.24 2.03e-06 GO:0050789 regulation of biological process
1.41 2.45e-06 GO:0051179 localization
1.24 2.99e-06 GO:0050794 regulation of cellular process
2.28 5.09e-06 GO:0019226 transmission of nerve impulse
2.28 5.09e-06 GO:0035637 multicellular organismal signaling
1.46 5.38e-06 GO:0048731 system development
1.59 5.89e-06 GO:0048583 regulation of response to stimulus
1.52 7.13e-06 GO:0042221 response to chemical stimulus
1.74 8.56e-06 GO:0002376 immune system process
2.35 8.63e-06 GO:0007268 synaptic transmission
2.14 1.31e-05 GO:0050878 regulation of body fluid levels
1.71 1.90e-05 GO:0051239 regulation of multicellular organismal process
1.41 3.06e-05 GO:0048856 anatomical structure development
1.83 3.66e-05 GO:0070887 cellular response to chemical stimulus
1.92 6.28e-05 GO:0006955 immune response
1.40 1.01e-04 GO:0006810 transport
1.60 1.71e-04 GO:0009653 anatomical structure morphogenesis
1.45 2.17e-04 GO:0006950 response to stress
1.39 2.18e-04 GO:0051234 establishment of localization
1.56 2.83e-04 GO:0023051 regulation of signaling
2.08 5.19e-04 GO:0007596 blood coagulation
2.08 5.19e-04 GO:0050817 coagulation
1.97 6.43e-04 GO:0042060 wound healing
2.07 6.46e-04 GO:0007599 hemostasis
1.72 9.26e-04 GO:0032879 regulation of localization
1.49 1.12e-03 GO:0048513 organ development
1.57 1.67e-03 GO:0009966 regulation of signal transduction
1.88 1.70e-03 GO:0007167 enzyme linked receptor protein signaling pathway
2.47 1.83e-03 GO:0008361 regulation of cell size
2.19 2.30e-03 GO:0090066 regulation of anatomical structure size
1.73 3.22e-03 GO:0040011 locomotion
1.72 3.39e-03 GO:0006811 ion transport
1.93 3.81e-03 GO:0006928 cellular component movement
1.48 4.47e-03 GO:0003008 system process
1.64 4.64e-03 GO:0010646 regulation of cell communication
2.05 4.85e-03 GO:0032583 regulation of gene-specific transcription
3.89 5.99e-03 GO:0016049 cell growth
1.82 6.08e-03 GO:0042325 regulation of phosphorylation
3.07 6.12e-03 GO:0001763 morphogenesis of a branching structure
2.20 6.14e-03 GO:0044057 regulation of system process
2.63 6.71e-03 GO:0048732 gland development
1.73 6.79e-03 GO:0006952 defense response
2.06 7.17e-03 GO:0016477 cell migration
1.38 7.48e-03 GO:0048522 positive regulation of cellular process
1.79 8.16e-03 GO:0019220 regulation of phosphate metabolic process
1.79 8.16e-03 GO:0051174 regulation of phosphorus metabolic process
1.99 8.55e-03 GO:0048870 cell motility
1.99 8.55e-03 GO:0051674 localization of cell
1.52 8.66e-03 GO:0065009 regulation of molecular function
14.17 1.06e-02 GO:0002456 T cell mediated immunity
2.17 1.20e-02 GO:0032535 regulation of cellular component size
2.19 1.23e-02 GO:0051046 regulation of secretion
3.48 1.45e-02 GO:0030879 mammary gland development
2.76 1.50e-02 GO:0050900 leukocyte migration
1.41 1.55e-02 GO:0030154 cell differentiation
1.89 1.93e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
3.14 2.10e-02 GO:0061138 morphogenesis of a branching epithelium
1.96 2.31e-02 GO:0051094 positive regulation of developmental process
3.70 2.39e-02 GO:0050708 regulation of protein secretion
1.78 2.56e-02 GO:0001932 regulation of protein phosphorylation
2.74 2.69e-02 GO:0042445 hormone metabolic process
1.64 2.69e-02 GO:0050793 regulation of developmental process
1.39 2.94e-02 GO:0048869 cellular developmental process
1.52 3.29e-02 GO:0010033 response to organic substance
2.46 3.73e-02 GO:0010817 regulation of hormone levels
1.79 3.96e-02 GO:0009887 organ morphogenesis
3.54 4.12e-02 GO:0022612 gland morphogenesis
1.74 4.18e-02 GO:0009719 response to endogenous stimulus
2.07 4.53e-02 GO:0043434 response to peptide hormone stimulus
1.75 4.57e-02 GO:0071310 cellular response to organic substance

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.72 3.52e-13 GO:0044459 plasma membrane part
1.97 4.98e-12 GO:0005887 integral to plasma membrane
1.93 2.14e-11 GO:0031226 intrinsic to plasma membrane
1.38 1.99e-08 GO:0005886 plasma membrane
1.37 7.06e-08 GO:0071944 cell periphery
1.54 9.10e-07 GO:0005576 extracellular region
1.90 4.77e-06 GO:0005615 extracellular space
1.72 2.84e-05 GO:0044421 extracellular region part
2.19 1.32e-04 GO:0009986 cell surface
1.74 4.69e-04 GO:0031982 vesicle
1.76 5.13e-04 GO:0031410 cytoplasmic vesicle
2.55 7.97e-04 GO:0030141 stored secretory granule
1.74 1.54e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.73 1.55e-03 GO:0031988 membrane-bounded vesicle
1.62 9.98e-03 GO:0005626 insoluble fraction
1.53 1.03e-02 GO:0000267 cell fraction
2.29 1.34e-02 GO:0034702 ion channel complex
1.60 1.91e-02 GO:0005624 membrane fraction
2.15 3.03e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 3.57e-07 GO:0005102 receptor binding
2.39 7.73e-07 GO:0015267 channel activity
2.38 8.49e-07 GO:0022803 passive transmembrane transporter activity
1.88 2.46e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.84 2.84e-06 GO:0022857 transmembrane transporter activity
1.71 6.34e-06 GO:0005215 transporter activity
2.29 1.36e-05 GO:0022838 substrate-specific channel activity
1.74 3.17e-05 GO:0022892 substrate-specific transporter activity
1.88 3.35e-05 GO:0015075 ion transmembrane transporter activity
2.23 5.42e-05 GO:0005216 ion channel activity
2.37 1.09e-04 GO:0022836 gated channel activity
1.94 3.67e-04 GO:0008324 cation transmembrane transporter activity
1.96 4.33e-03 GO:0008289 lipid binding
3.36 5.85e-03 GO:0015294 solute:cation symporter activity
4.10 7.07e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.86 7.95e-03 GO:0015276 ligand-gated ion channel activity
2.86 7.95e-03 GO:0022834 ligand-gated channel activity
2.19 9.43e-03 GO:0005261 cation channel activity
1.16 1.33e-02 GO:0005515 protein binding
4.00 1.97e-02 GO:0003707 steroid hormone receptor activity
5.67 2.86e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
4.07 3.58e-02 GO:0001948 glycoprotein binding