Motif ID: EP300.p2

Z-value: 1.750


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_41487787-0.211.6e-03Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_4851688 32.663 PFN1
profilin 1
chr17_-_4851797 28.459 NM_005022
 PFN1
profilin 1
chr6_-_86352656 27.280 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr12_+_6309475 26.621 NM_001769
 CD9
CD9 molecule
chr6_-_86352696 25.782 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr17_-_4851827 25.320 PFN1
profilin 1
chr6_-_86352650 24.533 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr6_-_86352564 23.074 NM_001159674
NM_001253771
 SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr6_-_86352635 19.353 NM_001159673
 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr14_-_69446038 18.989 NM_001102
NM_001130004
NM_001130005
 ACTN1


actinin, alpha 1


chr1_+_156084579 18.174 LMNA
lamin A/C
chr1_-_108742963 17.798 NM_013386
 SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr14_-_69446008 17.243 ACTN1
actinin, alpha 1
chr11_+_1968586 17.160 MRPL23
mitochondrial ribosomal protein L23
chr14_-_69445948 17.069 ACTN1
actinin, alpha 1
chr14_-_69445989 17.061 ACTN1
actinin, alpha 1
chr14_-_69445978 16.998 ACTN1
actinin, alpha 1
chr13_-_99229037 16.843 STK24
serine/threonine kinase 24
chr14_-_69445974 16.203 ACTN1
actinin, alpha 1
chr1_-_20987881 15.969 DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 171 entries
enrichment   p-value GO term description
3.00 3.62e-02 GO:0050434 positive regulation of viral transcription
2.97 1.41e-02 GO:0046782 regulation of viral transcription
2.77 2.98e-02 GO:0048524 positive regulation of viral reproduction
2.75 1.64e-04 GO:0043241 protein complex disassembly
2.75 1.64e-04 GO:0043624 cellular protein complex disassembly
2.67 9.18e-05 GO:0032984 macromolecular complex disassembly
2.67 9.18e-05 GO:0034623 cellular macromolecular complex disassembly
2.66 2.48e-03 GO:0006415 translational termination
2.66 3.97e-03 GO:0019080 viral genome expression
2.66 3.97e-03 GO:0019083 viral transcription
2.58 1.32e-03 GO:0006414 translational elongation
2.54 6.38e-08 GO:0022411 cellular component disassembly
2.54 6.38e-08 GO:0071845 cellular component disassembly at cellular level
2.35 1.05e-03 GO:0019058 viral infectious cycle
2.32 7.93e-04 GO:0034330 cell junction organization
2.28 4.64e-04 GO:0022415 viral reproductive process
2.25 3.57e-03 GO:0031016 pancreas development
2.25 9.23e-03 GO:0034329 cell junction assembly
2.25 2.39e-02 GO:0031018 endocrine pancreas development
2.23 2.26e-02 GO:0042254 ribosome biogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
4.67 4.37e-02 GO:0030684 preribosome
2.91 1.91e-03 GO:0030496 midbody
2.57 8.50e-04 GO:0042470 melanosome
2.57 8.50e-04 GO:0048770 pigment granule
2.54 8.94e-03 GO:0022626 cytosolic ribosome
2.23 2.39e-02 GO:0005925 focal adhesion
2.20 2.24e-02 GO:0005924 cell-substrate adherens junction
2.19 1.74e-02 GO:0030055 cell-substrate junction
2.03 3.72e-03 GO:0070161 anchoring junction
2.03 1.04e-02 GO:0005912 adherens junction
2.00 1.77e-11 GO:0030529 ribonucleoprotein complex
1.97 4.23e-02 GO:0031965 nuclear membrane
1.95 3.64e-04 GO:0005635 nuclear envelope
1.87 2.92e-02 GO:0031252 cell leading edge
1.83 1.70e-07 GO:0005730 nucleolus
1.74 5.71e-03 GO:0015629 actin cytoskeleton
1.64 1.01e-22 GO:0005829 cytosol
1.63 4.50e-25 GO:0031974 membrane-enclosed lumen
1.63 1.42e-24 GO:0043233 organelle lumen
1.63 8.47e-24 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.55 8.99e-03 GO:0003729 mRNA binding
2.00 2.99e-02 GO:0003735 structural constituent of ribosome
1.78 8.50e-03 GO:0032403 protein complex binding
1.70 4.10e-09 GO:0003723 RNA binding
1.59 4.32e-02 GO:0003712 transcription cofactor activity
1.59 4.73e-02 GO:0000988 protein binding transcription factor activity
1.59 4.73e-02 GO:0000989 transcription factor binding transcription factor activity
1.54 8.96e-03 GO:0008092 cytoskeletal protein binding
1.46 4.51e-02 GO:0005198 structural molecule activity
1.43 2.16e-02 GO:0019899 enzyme binding
1.41 1.79e-56 GO:0005515 protein binding
1.24 7.48e-03 GO:0000166 nucleotide binding
1.18 4.61e-05 GO:0003824 catalytic activity
1.16 4.48e-27 GO:0005488 binding