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• Activity deltas table
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Motif ID: ESR1.p2

Z-value: 1.511

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_122618098	18.228		ANXA5	annexin A5
chr5_+_150400132	17.435		GPX3	glutathione peroxidase 3 (plasma)
chr4_-_122618129	17.346		ANXA5	annexin A5
chr4_-_122618140	16.964	NM_001154	ANXA5	annexin A5
chr13_+_110959592	16.813	NM_001846	COL4A2	collagen, type IV, alpha 2
chr4_-_57976550	16.598	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr11_+_832965	14.888		CD151	CD151 molecule (Raph blood group)
chr17_-_3571905	13.636	NM_001204698 NM_014604	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chr5_+_150399980	12.952	NM_002084	GPX3	glutathione peroxidase 3 (plasma)
chr12_-_56122124	12.747		CD63	CD63 molecule
chr6_+_7541837	12.692		DSP	desmoplakin
chr11_+_129939792	11.672		APLP2	amyloid beta (A4) precursor-like protein 2
chr5_+_178286913	11.602	NM_058230	ZNF354B	zinc finger protein 354B
chr17_-_74707000	11.556	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr7_-_47621635	11.450		TNS3	tensin 3
chr7_-_47621741	11.346	NM_022748	TNS3	tensin 3
chr17_-_3571819	11.339		TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chr14_+_105941061	11.068	NM_001312	CRIP2	cysteine-rich protein 2
chr1_-_201476248	10.863	NM_001193570 NM_004078	CSRP1	cysteine and glycine-rich protein 1
chr1_-_201476241	10.847		CSRP1	cysteine and glycine-rich protein 1
chr6_+_7541863	10.794	NM_001008844 NM_004415	DSP	desmoplakin
chr6_+_7541892	10.782		DSP	desmoplakin
chr11_+_129939787	10.744		APLP2	amyloid beta (A4) precursor-like protein 2
chr1_-_201476218	10.650		CSRP1	cysteine and glycine-rich protein 1
chr11_+_129939807	10.527		APLP2	amyloid beta (A4) precursor-like protein 2
chr13_-_110959441	10.490	NM_001845	COL4A1	collagen, type IV, alpha 1
chr6_+_148663953	10.394		SASH1	SAM and SH3 domain containing 1
chr1_-_201475966	10.331	NM_001193571	CSRP1	cysteine and glycine-rich protein 1
chr11_-_63381940	10.315	NM_001128203	PLA2G16	phospholipase A2, group XVI
chr16_+_56659584	10.246	NM_175617	MT1E	metallothionein 1E
chr11_-_63381840	10.031		PLA2G16	phospholipase A2, group XVI
chr1_+_19923457	9.915	NM_001204088 NM_001204089 NM_001032363 NM_001204082 NM_001204083	C1orf151-NBL1 MINOS1	C1orf151-NBL1 readthrough mitochondrial inner membrane organizing system 1
chr9_+_123963728	9.892		GSN	gelsolin
chr11_-_63381485	9.862		PLA2G16	phospholipase A2, group XVI
chr8_+_98881277	9.783	NM_002380 NM_030583	MATN2	matrilin 2
chr11_-_63381907	9.747	NM_007069	PLA2G16	phospholipase A2, group XVI
chr11_+_129939667	9.602	NM_001142276 NM_001142277 NM_001142278 NM_001642	APLP2	amyloid beta (A4) precursor-like protein 2
chr11_-_1785190	9.479	NM_001909	CTSD	cathepsin D
chr6_+_148663728	9.477	NM_015278	SASH1	SAM and SH3 domain containing 1
chr17_-_48264039	9.232		COL1A1	collagen, type I, alpha 1
chr18_+_55711890	9.099		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr11_-_33757872	8.966	NM_000611 NM_203329 NM_203330 NM_203331	CD59	CD59 molecule, complement regulatory protein
chr7_+_75931829	8.926	NM_001540	HSPB1	heat shock 27kDa protein 1
chr7_+_75931991	8.923		HSPB1	heat shock 27kDa protein 1
chr16_+_55515468	8.510	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr6_+_31783280	8.465	NM_005345	HSPA1A	heat shock 70kDa protein 1A
chr9_+_97488943	8.459	NM_001193331 NM_032823	C9orf3	chromosome 9 open reading frame 3
chr9_+_97488993	8.444		C9orf3	chromosome 9 open reading frame 3
chr5_-_122372413	8.384	NM_000943	PPIC	peptidylprolyl isomerase C (cyclophilin C)
chr11_+_832909	8.318	NM_001039490 NM_004357 NM_139029 NM_139030	CD151	CD151 molecule (Raph blood group)
chr8_+_38854431	7.942	NM_003816	ADAM9	ADAM metallopeptidase domain 9
chr11_+_833007	7.923		CD151	CD151 molecule (Raph blood group)
chr20_-_62130390	7.867	NM_001958	EEF1A2	eukaryotic translation elongation factor 1 alpha 2
chr4_-_17513676	7.797	NM_000320	QDPR	quinoid dihydropteridine reductase
chr22_+_33197678	7.776		TIMP3	TIMP metallopeptidase inhibitor 3
chr8_+_38854524	7.662		ADAM9	ADAM metallopeptidase domain 9
chrX_+_134166318	7.644	NM_001078171	FAM127A	family with sequence similarity 127, member A
chr2_-_85641153	7.622		CAPG	capping protein (actin filament), gelsolin-like
chr6_+_31783314	7.622		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr11_-_1785104	7.494		CTSD	cathepsin D
chr21_+_42540054	7.232		BACE2	beta-site APP-cleaving enzyme 2
chr3_-_133748828	7.192	NM_005630	SLCO2A1	solute carrier organic anion transporter family, member 2A1
chr2_-_20425166	7.186	NM_001006946	SDC1	syndecan 1
chr22_+_38142316	6.973		TRIOBP	TRIO and F-actin binding protein
chr11_+_129939847	6.896		APLP2	amyloid beta (A4) precursor-like protein 2
chr21_+_42540092	6.878		BACE2	beta-site APP-cleaving enzyme 2
chr1_-_94702916	6.824		ARHGAP29	Rho GTPase activating protein 29
chr3_+_171757413	6.730	NM_022763	FNDC3B	fibronectin type III domain containing 3B
chr22_+_33197744	6.673		TIMP3	TIMP metallopeptidase inhibitor 3
chr17_-_74707066	6.614		MXRA7	matrix-remodelling associated 7
chr21_-_45196200	6.550	NM_000100	CSTB	cystatin B (stefin B)
chr21_-_45196149	6.505		CSTB	cystatin B (stefin B)
chr9_-_138987096	6.464	NM_144653	NACC2	NACC family member 2, BEN and BTB (POZ) domain containing
chr6_+_148664124	6.415		SASH1	SAM and SH3 domain containing 1
chr3_-_133748727	6.386		SLCO2A1	solute carrier organic anion transporter family, member 2A1
chr5_+_179248089	6.385		SQSTM1	sequestosome 1
chr22_+_38142255	6.332		TRIOBP	TRIO and F-actin binding protein
chr2_-_85641128	6.323		CAPG	capping protein (actin filament), gelsolin-like
chr1_-_167522979	6.307		CREG1	cellular repressor of E1A-stimulated genes 1
chr7_+_75932865	6.260		HSPB1	heat shock 27kDa protein 1
chr1_-_68299047	6.223	NM_018841	GNG12	guanine nucleotide binding protein (G protein), gamma 12
chr20_+_48807365	6.168		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr5_+_179247911	6.140		SQSTM1	sequestosome 1
chr9_+_114393543	6.136	NM_001015882 NM_004125	DNAJC25 DNAJC25-GNG10	DnaJ (Hsp40) homolog, subfamily C , member 25 DNAJC25-GNG10 readthrough
chr1_-_167523016	6.111	NM_003851	CREG1	cellular repressor of E1A-stimulated genes 1
chr15_+_22892699	6.072		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr6_+_30294224	5.846
chr15_+_101420004	5.801	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr19_-_4400470	5.797	NM_001199943 NM_003025	SH3GL1	SH3-domain GRB2-like 1
chr15_+_41136622	5.778	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_-_94703252	5.762	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr11_-_1785087	5.659		CTSD	cathepsin D
chr11_-_1785126	5.617		CTSD	cathepsin D
chr1_-_59042827	5.604		TACSTD2	tumor-associated calcium signal transducer 2
chr1_-_27816542	5.515		WASF2	WAS protein family, member 2
chr15_+_22892683	5.466	NM_014608	CYFIP1	cytoplasmic FMR1 interacting protein 1
chr15_+_101420032	5.433		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr15_+_41136178	5.431	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr3_-_46505077	5.380	NM_001199149	LTF	lactotransferrin
chr1_+_151512760	5.373	NM_001126337 NM_020127	TUFT1	tuftelin 1
chr20_-_23618382	5.366	NM_000099	CST3	cystatin C
chr16_-_3074225	5.358	NM_001002017 NM_001002018 NM_017885	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)
chr14_+_65007163	5.353	NM_021979	HSPA2	heat shock 70kDa protein 2
chr5_+_179247903	5.324		SQSTM1	sequestosome 1
chr1_+_223900061	5.286	NM_001748	CAPN2	calpain 2, (m/II) large subunit
chr2_-_216300770	5.174	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr16_+_56659679	5.169		MT1E	metallothionein 1E
chr19_+_45349560	5.146		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr22_+_19929310	5.108		COMT	catechol-O-methyltransferase
chr22_-_19166276	5.005		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr3_-_81810816	4.961		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr2_-_110371669	4.953	NM_144710 NM_178584	SEPT10	septin 10
chr2_-_47168902	4.942	NM_001171508 NM_001171511	MCFD2	multiple coagulation factor deficiency 2
chr14_-_21493858	4.934		NDRG2	NDRG family member 2
chr14_-_21493910	4.930	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr15_+_22892723	4.883		CYFIP1	cytoplasmic FMR1 interacting protein 1
chr12_-_123756164	4.802	NM_004642	CDK2AP1	cyclin-dependent kinase 2 associated protein 1
chr2_+_182756468	4.799	NM_001130445 NM_006751	SSFA2	sperm specific antigen 2
chr7_+_143079354	4.795		ZYX	zyxin
chr22_-_19166133	4.763		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr1_+_223900212	4.746		CAPN2	calpain 2, (m/II) large subunit
chr14_-_69445772	4.700		ACTN1	actinin, alpha 1
chr14_+_65007418	4.660		HSPA2	heat shock 70kDa protein 2
chr17_+_57785011	4.656		VMP1	vacuole membrane protein 1
chr17_-_1303402	4.643		YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr19_-_4400357	4.641	NM_001199944	SH3GL1	SH3-domain GRB2-like 1
chr12_+_66218879	4.627		HMGA2	high mobility group AT-hook 2
chr8_+_82192717	4.626	NM_001444	FABP5	fatty acid binding protein 5 (psoriasis-associated)
chr12_+_19282402	4.602	NM_001143821 NM_001190860 NM_019012	PLEKHA5	pleckstrin homology domain containing, family A member 5
chr15_-_72523713	4.597	NM_001206796 NM_001206797 NM_001206798 NM_002654 NM_182470 NM_182471	PKM2	pyruvate kinase, muscle
chr11_+_842821	4.584	NM_001025238 NM_001025239 NM_003271 NM_001025235 NM_001025236	TSPAN4	tetraspanin 4
chr15_-_79237320	4.564		CTSH	cathepsin H
chr2_-_1748317	4.548		PXDN	peroxidasin homolog (Drosophila)
chr11_-_82611358	4.536	NM_005040 NM_199418	PRCP	prolylcarboxypeptidase (angiotensinase C)
chr11_-_62314291	4.484	NM_001620 NM_024060	AHNAK	AHNAK nucleoprotein
chr10_-_97050671	4.480	NM_020992	PDLIM1	PDZ and LIM domain 1
chr18_+_29078026	4.438	NM_001943	DSG2	desmoglein 2
chr19_+_15218141	4.434	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr6_+_17393610	4.430	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr1_+_223900226	4.430		CAPN2	calpain 2, (m/II) large subunit
chr22_-_19166296	4.402	NM_005984	SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_+_119981389	4.394		STEAP3	STEAP family member 3, metalloreductase
chr16_+_66400524	4.365	NM_001795	CDH5	cadherin 5, type 2 (vascular endothelium)
chr6_-_47277354	4.344		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr10_-_79686279	4.343	NM_004747	DLG5	discs, large homolog 5 (Drosophila)
chr9_+_112810877	4.329	NM_001004065 NM_001198656	AKAP2	A kinase (PRKA) anchor protein 2
chr9_+_137533643	4.288	NM_000093	COL5A1	collagen, type V, alpha 1
chr5_-_10761341	4.286		DAP	death-associated protein
chr1_-_150241210	4.279		APH1A	anterior pharynx defective 1 homolog A (C. elegans)
chr17_+_35849997	4.270		DUSP14	dual specificity phosphatase 14
chr17_+_35849950	4.252	NM_007026	DUSP14	dual specificity phosphatase 14
chrX_+_135229536	4.242	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr5_+_131593388	4.226		PDLIM4	PDZ and LIM domain 4
chr9_-_99382073	4.219	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr18_-_21977785	4.211	NM_080597	OSBPL1A	oxysterol binding protein-like 1A
chr7_+_44143945	4.196	NM_001129	AEBP1	AE binding protein 1
chr12_-_50677238	4.183	NM_001113546 NM_016357	LIMA1	LIM domain and actin binding 1
chr14_-_103988829	4.157		CKB	creatine kinase, brain
chr19_+_676346	4.156	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr11_+_394238	4.155		PKP3	plakophilin 3
chr2_+_85360373	4.109	NM_031283	TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)
chr9_+_706744	4.099	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr14_-_93214873	4.095	NM_001008530 NM_005606	LGMN	legumain
chr20_+_55204307	4.080	NM_003222	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr15_-_79237353	4.079	NM_004390	CTSH	cathepsin H
chr6_+_29894105	4.064
chr11_+_120206903	4.056		ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12
chr9_+_19049424	4.004		RRAGA	Ras-related GTP binding A
chr16_+_66968319	3.991	NM_003869 NM_198061	CES2	carboxylesterase 2
chr21_-_43373938	3.976	NM_015500	C2CD2	C2 calcium-dependent domain containing 2
chr6_-_47277246	3.963		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr22_+_38302296	3.935		MICALL1	MICAL-like 1
chr20_-_23030141	3.897	NM_000361	THBD	thrombomodulin
chr17_-_1303548	3.886	NM_006761	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr5_-_151138139	3.877	NM_004045	ATOX1	ATX1 antioxidant protein 1 homolog (yeast)
chr7_+_44144002	3.851		AEBP1	AE binding protein 1
chr1_-_95392501	3.845	NM_001839	CNN3	calponin 3, acidic
chr16_+_66968360	3.834		CES2	carboxylesterase 2
chr9_+_133589267	3.833	NM_007313	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr22_-_19165872	3.826		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr15_+_90808833	3.792	NM_001033088	NGRN	neugrin, neurite outgrowth associated
chr21_+_34775740	3.771		IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)
chr5_-_10761344	3.757	NM_004394	DAP	death-associated protein
chr16_+_66968390	3.739		CES2	carboxylesterase 2
chr2_-_175869910	3.704	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr1_-_23857711	3.678	NM_004091	E2F2	E2F transcription factor 2
chr5_-_10761179	3.669		DAP	death-associated protein
chr12_-_56709831	3.668	NM_001190991 NM_014255	CNPY2	canopy 2 homolog (zebrafish)
chr11_+_64001974	3.663	NM_001243733 NM_003377	VEGFB	vascular endothelial growth factor B
chr19_+_40872709	3.661		PLD3	phospholipase D family, member 3
chr1_-_21978287	3.645	NM_001145658	RAP1GAP	RAP1 GTPase activating protein
chr19_-_17356022	3.603	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr3_+_52529370	3.581		STAB1	stabilin 1
chr9_-_89562103	3.574	NM_002048	GAS1	growth arrest-specific 1
chr10_-_126849556	3.556	NM_001083914	CTBP2	C-terminal binding protein 2
chr19_+_35607218	3.533		FXYD3	FXYD domain containing ion transport regulator 3
chr10_+_75670861	3.532	NM_001145031 NM_002658	PLAU	plasminogen activator, urokinase
chr20_+_62372436	3.530		SLC2A4RG	SLC2A4 regulator
chr16_+_15068832	3.530	NM_015027	PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr2_-_224903933	3.527	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	6.61e-13	GO:0009987	cellular process
1.22	5.00e-08	GO:0065007	biological regulation
1.23	2.49e-07	GO:0050794	regulation of cellular process
1.50	3.19e-07	GO:0042221	response to chemical stimulus
1.36	6.13e-07	GO:0023052	signaling
1.50	8.74e-07	GO:0065008	regulation of biological quality
1.37	3.46e-06	GO:0007165	signal transduction
1.21	4.73e-06	GO:0050789	regulation of biological process
1.32	5.11e-06	GO:0051716	cellular response to stimulus
1.59	1.55e-05	GO:0009966	regulation of signal transduction
1.36	2.49e-05	GO:0048856	anatomical structure development
1.59	3.13e-05	GO:0035556	intracellular signal transduction
1.22	4.94e-05	GO:0050896	response to stimulus
1.52	9.09e-05	GO:0023051	regulation of signaling
1.31	1.15e-04	GO:0032502	developmental process
1.19	1.50e-04	GO:0008152	metabolic process
1.40	2.61e-04	GO:0048519	negative regulation of biological process
1.36	2.97e-04	GO:0048731	system development
1.38	4.25e-04	GO:0048522	positive regulation of cellular process
1.65	4.81e-04	GO:0032879	regulation of localization
2.26	5.71e-04	GO:0030029	actin filament-based process
1.50	7.48e-04	GO:0009653	anatomical structure morphogenesis
1.61	8.28e-04	GO:0010646	regulation of cell communication
1.40	1.02e-03	GO:0048523	negative regulation of cellular process
2.23	1.20e-03	GO:0001944	vasculature development
1.54	1.40e-03	GO:0010033	response to organic substance
1.92	1.79e-03	GO:0072358	cardiovascular system development
1.92	1.79e-03	GO:0072359	circulatory system development
1.43	2.18e-03	GO:0044281	small molecule metabolic process
2.24	2.72e-03	GO:0001568	blood vessel development
1.33	3.32e-03	GO:0048518	positive regulation of biological process
2.24	3.32e-03	GO:0030334	regulation of cell migration
2.17	3.38e-03	GO:0051270	regulation of cellular component movement
1.29	3.38e-03	GO:0007275	multicellular organismal development
2.22	4.58e-03	GO:2000145	regulation of cell motility
1.40	5.31e-03	GO:0048583	regulation of response to stimulus
1.59	7.61e-03	GO:0070887	cellular response to chemical stimulus
2.21	8.48e-03	GO:0030036	actin cytoskeleton organization
1.27	1.20e-02	GO:0016043	cellular component organization
1.45	1.26e-02	GO:0007399	nervous system development
1.81	1.26e-02	GO:0044283	small molecule biosynthetic process
1.18	1.38e-02	GO:0044237	cellular metabolic process
1.61	1.54e-02	GO:0051128	regulation of cellular component organization
1.95	1.58e-02	GO:0090066	regulation of anatomical structure size
2.08	1.82e-02	GO:0040012	regulation of locomotion
1.58	1.84e-02	GO:0051704	multi-organism process
2.00	1.91e-02	GO:0032535	regulation of cellular component size
1.57	1.95e-02	GO:0050793	regulation of developmental process
1.55	2.08e-02	GO:0042127	regulation of cell proliferation
1.17	2.54e-02	GO:0044238	primary metabolic process
1.67	3.74e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.70	3.79e-02	GO:0042060	wound healing
1.25	4.43e-02	GO:0071840	cellular component organization or biogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.29	4.78e-20	GO:0005737	cytoplasm
1.33	3.31e-14	GO:0044444	cytoplasmic part
1.15	3.90e-12	GO:0005622	intracellular
1.16	4.35e-12	GO:0044424	intracellular part
2.28	2.74e-05	GO:0015629	actin cytoskeleton
1.70	7.13e-05	GO:0005624	membrane fraction
1.68	9.15e-05	GO:0005626	insoluble fraction
1.06	1.71e-04	GO:0044464	cell part
1.57	1.72e-04	GO:0000267	cell fraction
1.06	1.76e-04	GO:0005623	cell
1.12	2.34e-04	GO:0043229	intracellular organelle
1.12	2.45e-04	GO:0043226	organelle
1.45	4.54e-04	GO:0005856	cytoskeleton
2.55	5.02e-04	GO:0070161	anchoring junction
1.36	1.63e-03	GO:0005829	cytosol
1.72	1.68e-03	GO:0030054	cell junction
1.35	2.00e-03	GO:0044459	plasma membrane part
1.18	4.17e-03	GO:0044446	intracellular organelle part
2.46	4.81e-03	GO:0005912	adherens junction
1.18	5.19e-03	GO:0044422	organelle part
1.91	5.21e-03	GO:0048471	perinuclear region of cytoplasm
2.22	7.36e-03	GO:0005911	cell-cell junction
1.48	7.79e-03	GO:0005783	endoplasmic reticulum
1.50	1.05e-02	GO:0005794	Golgi apparatus
1.12	1.08e-02	GO:0043231	intracellular membrane-bounded organelle
1.12	1.28e-02	GO:0043227	membrane-bounded organelle
2.75	3.09e-02	GO:0042470	melanosome
2.75	3.09e-02	GO:0048770	pigment granule
1.39	3.68e-02	GO:0005739	mitochondrion
4.11	3.70e-02	GO:0042641	actomyosin
2.61	4.16e-02	GO:0005925	focal adhesion
1.19	4.42e-02	GO:0071944	cell periphery

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.35	4.76e-23	GO:0005515	protein binding
1.14	1.16e-11	GO:0005488	binding
1.90	7.09e-05	GO:0008092	cytoskeletal protein binding
1.75	8.30e-05	GO:0019899	enzyme binding
3.35	8.17e-04	GO:0019199	transmembrane receptor protein kinase activity
1.99	4.12e-03	GO:0003779	actin binding
1.62	4.73e-03	GO:0042802	identical protein binding
3.06	1.11e-02	GO:0005201	extracellular matrix structural constituent
2.67	2.10e-02	GO:0019838	growth factor binding
1.60	3.00e-02	GO:0046983	protein dimerization activity