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• Activity deltas table
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Motif ID: FEV.p2

Z-value: 1.782

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_6798419	46.096		ZNF384	zinc finger protein 384
chr12_-_6798619	45.236	NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr11_+_61129831	36.560		TMEM138	transmembrane protein 138
chr11_-_46722160	35.841		ARHGAP1	Rho GTPase activating protein 1
chr12_-_6798528	35.535	NM_133476	ZNF384	zinc finger protein 384
chr16_-_31085503	34.584	NM_024706	ZNF668	zinc finger protein 668
chr11_+_46722564	30.667	NM_001184751	ZNF408	zinc finger protein 408
chr16_+_31085722	29.201	NM_014699	ZNF646	zinc finger protein 646
chr11_+_61197574	28.782	NM_017841	SDHAF2	succinate dehydrogenase complex assembly factor 2
chr16_+_31085751	28.527		ZNF646	zinc finger protein 646
chr11_-_46722139	27.837		ARHGAP1	Rho GTPase activating protein 1
chr18_-_72264808	26.085		LOC400657	uncharacterized LOC400657
chr11_+_46722316	25.633	NM_024741	ZNF408	zinc finger protein 408
chr3_-_121379701	24.580		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr3_-_121379757	24.376	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr8_-_38034168	24.187		LSM1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_17935379	23.695	NM_001130009	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr16_-_31085073	23.283		ZNF668	zinc finger protein 668
chr18_-_72265038	23.277		LOC400657	uncharacterized LOC400657
chr14_+_69865095	22.703	NM_001252151 NM_001252152	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr14_+_69865380	22.319	NM_001252148 NM_001252150 NM_018375	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr6_+_111303240	22.133	NM_032194	RPF2	ribosome production factor 2 homolog (S. cerevisiae)
chr17_-_29641068	22.004		EVI2B	ecotropic viral integration site 2B
chr19_+_47759730	21.955	NM_015603	CCDC9	coiled-coil domain containing 9
chr19_+_47759802	21.568		CCDC9	coiled-coil domain containing 9
chr6_-_33239585	20.827	NM_022553	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr2_+_17935124	20.825	NM_182625	GEN1	Gen endonuclease homolog 1 (Drosophila)
chr22_-_19512859	20.793	NM_001130861 NM_003277	CLDN5	claudin 5
chr19_+_50879681	20.019	NM_007121	NR1H2	nuclear receptor subfamily 1, group H, member 2
chr4_-_88450601	19.242	NM_001128310 NM_004684	SPARCL1	SPARC-like 1 (hevin)
chr4_-_88450243	19.011		SPARCL1	SPARC-like 1 (hevin)
chr6_-_33239439	18.968		VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae)
chr1_-_183559669	18.615	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr6_-_33168448	18.077		RXRB	retinoid X receptor, beta
chr3_-_15468981	17.326	NM_152396	METTL6	methyltransferase like 6
chr16_+_1583657	17.282		TMEM204	transmembrane protein 204
chr11_+_71791376	17.273	NM_001145307 NM_001145308 NM_001205138 NM_145309	LRTOMT	leucine rich transmembrane and 0-methyltransferase domain containing
chr18_-_53177999	17.162	NM_001243231	TCF4	transcription factor 4
chr5_+_87564840	17.090		LOC100505894	uncharacterized LOC100505894
chr8_+_38034066	16.973	NM_001204878 NM_004874	BAG4	BCL2-associated athanogene 4
chr1_+_198608216	16.970		PTPRC	protein tyrosine phosphatase, receptor type, C
chrX_-_70288155	16.938	NM_013346	SNX12	sorting nexin 12
chr16_+_30710461	16.789	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr18_+_11851388	16.686	NM_020412	CHMP1B	charged multivesicular body protein 1B
chrX_+_128913881	16.192	NM_018990	SASH3	SAM and SH3 domain containing 3
chr11_-_46722115	16.159	NM_004308	ARHGAP1	Rho GTPase activating protein 1
chr15_-_71184611	16.119	NM_020147	THAP10	THAP domain containing 10
chr3_+_150264514	16.076	NM_032025	EIF2A	eukaryotic translation initiation factor 2A, 65kDa
chr3_+_15469052	15.841	NM_033083	EAF1	ELL associated factor 1
chr9_-_133454818	15.380		LOC100272217	uncharacterized LOC100272217
chr14_-_77923888	15.374	NM_001193314 NM_001193315 NM_001193316 NM_001193317 NM_022067	C14orf133	chromosome 14 open reading frame 133
chr17_-_29641094	15.309	NM_006495	EVI2B	ecotropic viral integration site 2B
chr15_+_71184781	15.259	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr1_+_169337193	15.243	NM_003666	BLZF1	basic leucine zipper nuclear factor 1
chr6_+_31515391	15.074		NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_+_171810611	15.023	NM_001136127 NM_015569	DNM3	dynamin 3
chr7_+_106505696	14.883		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr19_-_39826625	14.789		GMFG	glia maturation factor, gamma
chrX_+_128913897	14.719		SASH3	SAM and SH3 domain containing 3
chr11_-_71791734	14.637		NUMA1	nuclear mitotic apparatus protein 1
chr2_+_234160317	14.630		ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)
chr19_-_36505102	14.602		ALKBH6	alkB, alkylation repair homolog 6 (E. coli)
chr3_+_133494275	14.466		TF	transferrin
chr16_-_30366681	14.404	NM_006110	CD2BP2	CD2 (cytoplasmic tail) binding protein 2
chr21_-_46340874	14.334	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr16_+_2653350	14.146		LOC652276	potassium channel tetramerisation domain containing 5 pseudogene
chr19_+_3178735	14.145	NM_003775	S1PR4	sphingosine-1-phosphate receptor 4
chr16_+_69166538	14.133		CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)
chr11_-_75141015	14.052		KLHL35	kelch-like 35 (Drosophila)
chr11_+_63606535	14.026		MARK2	MAP/microtubule affinity-regulating kinase 2
chr8_+_38034296	13.981		BAG4	BCL2-associated athanogene 4
chr17_-_29641087	13.966		EVI2B	ecotropic viral integration site 2B
chr5_-_149535138	13.791		PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr1_-_183560010	13.588	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr10_-_72362441	13.558		PRF1	perforin 1 (pore forming protein)
chr3_-_128879873	13.427	NM_001204890 NM_001199469 NM_020701	ISY1-RAB43 ISY1	ISY1-RAB43 readthrough ISY1 splicing factor homolog (S. cerevisiae)
chr11_-_72433379	13.423	NM_001135190 NM_015242	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr1_-_183559463	13.337		NCF2	neutrophil cytosolic factor 2
chr1_+_156698270	13.307		RRNAD1	ribosomal RNA adenine dimethylase domain containing 1
chr1_+_198608136	13.284	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_-_62389571	13.251	NM_012200	B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr2_-_69870837	13.090		AAK1	AP2 associated kinase 1
chr1_-_160313056	13.063		COPA	coatomer protein complex, subunit alpha
chr4_-_46911223	13.035	NM_130902	COX7B2	cytochrome c oxidase subunit VIIb2
chr8_+_27182995	12.962	NM_173176	PTK2B	PTK2B protein tyrosine kinase 2 beta
chr6_-_32160289	12.931		GPSM3	G-protein signaling modulator 3
chr7_+_106505739	12.911		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_198608244	12.831		PTPRC	protein tyrosine phosphatase, receptor type, C
chr2_+_103035148	12.784	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr10_-_72362513	12.732	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr8_+_121457642	12.720	NM_022045	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr11_-_236833	12.674		SIRT3	sirtuin 3
chr22_+_37257004	12.632	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr5_-_1634099	12.615		LOC728613	programmed cell death 6 pseudogene
chr16_+_77225107	12.608		MON1B	MON1 homolog B (yeast)
chr8_+_27183047	12.481		PTK2B	PTK2B protein tyrosine kinase 2 beta
chr1_-_154193044	12.463		C1orf43	chromosome 1 open reading frame 43
chr5_-_130970851	12.460		RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr19_+_16222706	12.456		RAB8A	RAB8A, member RAS oncogene family
chr5_-_88178964	12.389		MEF2C	myocyte enhancer factor 2C
chr1_+_168148215	12.206		TIPRL	TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr5_-_93447237	12.058	NM_001163417 NM_001163418 NM_032042	FAM172A	family with sequence similarity 172, member A
chr2_-_69870705	12.055		AAK1	AP2 associated kinase 1
chr5_-_149535420	11.951	NM_002609	PDGFRB	platelet-derived growth factor receptor, beta polypeptide
chr6_+_31553955	11.858	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr19_+_56186426	11.796	NM_001130072 NM_013333	EPN1	epsin 1
chr12_+_58138663	11.627	NM_005981	TSPAN31	tetraspanin 31
chr19_+_57752051	11.621	NM_001023563 NM_001145078	ZNF805	zinc finger protein 805
chr19_-_4723791	11.616		DPP9	dipeptidyl-peptidase 9
chr10_+_75545363	11.422	NM_001242487 NM_001242488 NM_015037	KIAA0913	KIAA0913
chr11_+_63606598	11.407		MARK2	MAP/microtubule affinity-regulating kinase 2
chr16_+_30484049	11.385		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_150738255	11.361		CTSS	cathepsin S
chr1_+_111415791	11.357		CD53	CD53 molecule
chr20_+_10199455	11.356	NM_003081 NM_130811	SNAP25	synaptosomal-associated protein, 25kDa
chr19_-_36246411	11.325		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr5_-_130970907	11.321	NM_001164386 NM_001164387 NM_001164388 NM_001164389 NM_001164390 NM_016340	RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6
chr12_+_112856701	11.314		PTPN11	protein tyrosine phosphatase, non-receptor type 11
chr3_-_58563490	11.268	NM_001076778 NM_007177	FAM107A	family with sequence similarity 107, member A
chr6_+_31515352	11.267	NM_001144961 NM_005007	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr11_+_35684418	11.257		TRIM44	tripartite motif containing 44
chr17_+_18218569	11.216	NM_144775	SMCR8	Smith-Magenis syndrome chromosome region, candidate 8
chr17_-_19880991	11.204	NM_007202	AKAP10	A kinase (PRKA) anchor protein 10
chr6_+_31554475	11.193	NM_205837	LST1	leukocyte specific transcript 1
chr3_+_133465098	11.133		TF	transferrin
chr1_+_111415721	11.105	NM_000560	CD53	CD53 molecule
chrX_+_16737732	11.098		SYAP1	synapse associated protein 1
chr19_-_17375522	11.082	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chr14_-_93651242	11.076	NM_022151	MOAP1	modulator of apoptosis 1
chr20_-_48532036	11.024		SPATA2	spermatogenesis associated 2
chr19_+_16999871	10.937		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr19_-_4723755	10.911		DPP9	dipeptidyl-peptidase 9
chr8_+_24772454	10.822	NM_001105541	NEFM	neurofilament, medium polypeptide
chr19_+_56186610	10.766		EPN1	epsin 1
chr6_+_122793061	10.751	NM_181794	PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr9_-_130186491	10.741
chr19_+_15218141	10.728	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_-_29648631	10.717	NM_001003927 NM_014210	EVI2A	ecotropic viral integration site 2A
chr19_+_56186580	10.690		EPN1	epsin 1
chr11_-_3862183	10.687	NM_001665	RHOG	ras homolog gene family, member G (rho G)
chr16_+_29674564	10.679		SPN	sialophorin
chrY_+_2709596	10.675	NM_001008	RPS4Y1	ribosomal protein S4, Y-linked 1
chr2_-_136873740	10.617	NM_001008540	CXCR4	chemokine (C-X-C motif) receptor 4
chrY_+_2709630	10.613		RPS4Y1	ribosomal protein S4, Y-linked 1
chr11_+_63606346	10.597	NM_001039469 NM_001163296 NM_001163297 NM_004954	MARK2	MAP/microtubule affinity-regulating kinase 2
chr4_+_40198526	10.500	NM_004310	RHOH	ras homolog gene family, member H
chr17_-_79269082	10.395	NM_001037984 NM_138570	SLC38A10	solute carrier family 38, member 10
chr1_+_156698250	10.337	NM_001142560 NM_015997	RRNAD1	ribosomal RNA adenine dimethylase domain containing 1
chr11_+_124492770	10.300		TBRG1	transforming growth factor beta regulator 1
chr5_+_80597401	10.290	NM_001131035 NM_001131036 NM_032280	ZCCHC9	zinc finger, CCHC domain containing 9
chr12_-_6233684	10.250	NM_000552	VWF	von Willebrand factor
chr17_-_34313685	10.231	NM_032962 NM_032963	CCL14	chemokine (C-C motif) ligand 14
chr18_-_29522988	10.212		TRAPPC8	trafficking protein particle complex 8
chr16_+_30483959	10.148	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chrX_+_103031797	10.119		PLP1	proteolipid protein 1
chr16_+_77224827	10.117	NM_014940	MON1B	MON1 homolog B (yeast)
chr19_+_56186569	10.056		EPN1	epsin 1
chr6_-_153323787	10.049		MTRF1L	mitochondrial translational release factor 1-like
chr2_+_175260455	10.028	NM_001193528 NM_024583	SCRN3	secernin 3
chr11_+_60739114	10.004	NM_006725	CD6	CD6 molecule
chr1_+_10003485	10.004	NM_022787	NMNAT1	nicotinamide nucleotide adenylyltransferase 1
chr8_-_82395401	9.990	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr1_-_160312959	9.941
chr11_-_64885124	9.932	NM_014205	ZNHIT2	zinc finger, HIT-type containing 2
chr19_-_42746743	9.897		GSK3A	glycogen synthase kinase 3 alpha
chr1_+_160313061	9.866	NM_015331	NCSTN	nicastrin
chr5_+_130506656	9.837		LYRM7	Lyrm7 homolog (mouse)
chr1_-_79472360	9.826	NM_022159	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr5_+_156820161	9.785		CYFIP2	cytoplasmic FMR1 interacting protein 2
chr7_+_108210308	9.727		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_+_233925035	9.652	NM_001017915 NM_005541	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr1_-_150738232	9.641		CTSS	cathepsin S
chrX_+_70586113	9.633	NM_004606 NM_138923	TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr5_+_153418544	9.632		MFAP3	microfibrillar-associated protein 3
chr7_+_156742402	9.624	NM_138400	NOM1	nucleolar protein with MIF4G domain 1
chr9_-_88969323	9.609	NM_001185059 NM_001185074 NM_024617	ZCCHC6	zinc finger, CCHC domain containing 6
chr19_-_39826676	9.609	NM_004877	GMFG	glia maturation factor, gamma
chr14_-_80677839	9.604	NM_001007023 NM_001242502 NM_001242503 NM_013989	DIO2	deiodinase, iodothyronine, type II
chr6_+_111580481	9.589	NM_153369	KIAA1919	KIAA1919
chr19_-_6481765	9.553	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr2_+_233925104	9.522		INPP5D	inositol polyphosphate-5-phosphatase, 145kDa
chr19_-_36236291	9.522	NM_001040425 NM_144987	U2AF1L4	U2 small nuclear RNA auxiliary factor 1-like 4
chr16_+_75681634	9.510	NM_018975	TERF2IP	telomeric repeat binding factor 2, interacting protein
chr19_-_4559713	9.489	NM_032108	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr11_+_1874199	9.487	NM_002339	LSP1	lymphocyte-specific protein 1
chr17_-_37844266	9.433	NM_033419	PGAP3	post-GPI attachment to proteins 3
chr19_-_36399205	9.421	NM_001173514 NM_001173515 NM_003332 NM_198125	TYROBP	TYRO protein tyrosine kinase binding protein
chr8_+_22462286	9.415		KIAA1967	KIAA1967
chr5_-_79286793	9.350	NM_001010891 NM_001167741	MTX3	metaxin 3
chr19_-_36246206	9.343		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr8_+_22462273	9.329		KIAA1967	KIAA1967
chr7_+_108210291	9.312		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr19_-_36399183	9.289		TYROBP	TYRO protein tyrosine kinase binding protein
chr5_-_58652671	9.267	NM_001197219	PDE4D	phosphodiesterase 4D, cAMP-specific
chr7_+_86781869	9.259	NM_021145	DMTF1	cyclin D binding myb-like transcription factor 1
chr9_-_91793375	9.253		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr12_+_69742130	9.236	NM_000239	LYZ	lysozyme
chr7_+_86273951	9.229		GRM3	glutamate receptor, metabotropic 3
chr8_+_104427590	9.087		DCAF13	DDB1 and CUL4 associated factor 13
chr17_-_62084282	9.071	NM_000873	ICAM2	intercellular adhesion molecule 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.72	4.28e-28	GO:0002376	immune system process
1.92	5.03e-26	GO:0006955	immune response
1.20	4.59e-25	GO:0065007	biological regulation
1.13	1.42e-23	GO:0009987	cellular process
1.20	2.86e-22	GO:0050789	regulation of biological process
1.21	1.35e-20	GO:0050794	regulation of cellular process
1.32	5.86e-20	GO:0023052	signaling
1.34	2.01e-19	GO:0007165	signal transduction
1.29	1.36e-18	GO:0051716	cellular response to stimulus
1.80	1.09e-17	GO:0002682	regulation of immune system process
2.01	1.65e-17	GO:0002684	positive regulation of immune system process
1.44	2.58e-16	GO:0048583	regulation of response to stimulus
1.96	3.92e-16	GO:0050776	regulation of immune response
1.89	3.21e-15	GO:0001775	cell activation
1.65	4.58e-14	GO:0006952	defense response
1.19	1.15e-13	GO:0050896	response to stimulus
1.34	6.03e-13	GO:0006950	response to stress
2.08	1.10e-12	GO:0050778	positive regulation of immune response
1.39	6.03e-12	GO:0007166	cell surface receptor linked signaling pathway
2.10	6.09e-11	GO:0045321	leukocyte activation
2.28	6.30e-11	GO:0002764	immune response-regulating signaling pathway
1.55	8.05e-11	GO:0009611	response to wounding
2.28	1.55e-10	GO:0002757	immune response-activating signal transduction
2.13	1.57e-10	GO:0002253	activation of immune response
1.29	2.88e-10	GO:0048518	positive regulation of biological process
1.42	8.67e-10	GO:0035556	intracellular signal transduction
2.10	1.75e-09	GO:0051249	regulation of lymphocyte activation
2.00	4.40e-09	GO:0050865	regulation of cell activation
2.01	6.39e-09	GO:0002694	regulation of leukocyte activation
1.22	7.51e-09	GO:0019222	regulation of metabolic process
1.51	1.05e-08	GO:0006351	transcription, DNA-dependent
2.12	2.88e-08	GO:0050867	positive regulation of cell activation
1.47	3.33e-08	GO:0032774	RNA biosynthetic process
2.16	4.68e-08	GO:0051251	positive regulation of lymphocyte activation
1.78	5.28e-08	GO:0045087	innate immune response
2.10	9.56e-08	GO:0002696	positive regulation of leukocyte activation
1.50	1.89e-07	GO:0048584	positive regulation of response to stimulus
2.52	2.31e-07	GO:0050851	antigen receptor-mediated signaling pathway
1.27	5.26e-07	GO:0042221	response to chemical stimulus
1.17	8.02e-07	GO:0043170	macromolecule metabolic process
2.38	8.85e-07	GO:0002768	immune response-regulating cell surface receptor signaling pathway
2.20	1.13e-06	GO:0050870	positive regulation of T cell activation
1.82	1.43e-06	GO:0006954	inflammatory response
2.37	2.21e-06	GO:0002429	immune response-activating cell surface receptor signaling pathway
2.04	2.38e-06	GO:0050863	regulation of T cell activation
1.25	3.68e-06	GO:0048522	positive regulation of cellular process
1.36	3.85e-06	GO:0010033	response to organic substance
1.33	3.86e-06	GO:0065009	regulation of molecular function
1.97	4.17e-06	GO:0046649	lymphocyte activation
1.43	5.98e-06	GO:0051704	multi-organism process
1.20	6.31e-06	GO:0060255	regulation of macromolecule metabolic process
1.41	1.31e-05	GO:0042127	regulation of cell proliferation
1.33	1.40e-05	GO:0009966	regulation of signal transduction
1.19	1.66e-05	GO:0031323	regulation of cellular metabolic process
1.56	2.07e-05	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.84	2.42e-05	GO:0030168	platelet activation
1.30	3.43e-05	GO:0023051	regulation of signaling
1.16	4.31e-05	GO:0044260	cellular macromolecule metabolic process
1.42	4.65e-05	GO:0040011	locomotion
1.27	5.55e-05	GO:0006464	protein modification process
2.46	5.87e-05	GO:0050852	T cell receptor signaling pathway
2.23	5.95e-05	GO:0010518	positive regulation of phospholipase activity
2.18	7.26e-05	GO:0060193	positive regulation of lipase activity
1.37	9.97e-05	GO:0006793	phosphorus metabolic process
1.37	9.97e-05	GO:0006796	phosphate metabolic process
2.24	1.00e-04	GO:0007202	activation of phospholipase C activity
1.67	1.03e-04	GO:0031347	regulation of defense response
2.17	1.13e-04	GO:0010517	regulation of phospholipase activity
1.50	1.40e-04	GO:0050878	regulation of body fluid levels
2.22	1.46e-04	GO:0010863	positive regulation of phospholipase C activity
1.53	1.51e-04	GO:0007599	hemostasis
2.05	1.63e-04	GO:0060191	regulation of lipase activity
1.97	2.14e-04	GO:0002697	regulation of immune effector process
1.32	2.20e-04	GO:0051239	regulation of multicellular organismal process
1.22	2.53e-04	GO:0048519	negative regulation of biological process
2.10	2.84e-04	GO:0042110	T cell activation
1.25	2.89e-04	GO:0043412	macromolecule modification
1.52	3.18e-04	GO:0007596	blood coagulation
1.52	3.18e-04	GO:0050817	coagulation
1.21	3.36e-04	GO:0009889	regulation of biosynthetic process
1.47	3.52e-04	GO:0042060	wound healing
1.97	3.68e-04	GO:0002252	immune effector process
1.17	3.78e-04	GO:0080090	regulation of primary metabolic process
1.56	4.22e-04	GO:0007243	intracellular protein kinase cascade
1.56	4.22e-04	GO:0023014	signal transduction via phosphorylation event
1.45	4.89e-04	GO:0007167	enzyme linked receptor protein signaling pathway
1.41	5.39e-04	GO:0006468	protein phosphorylation
1.20	6.18e-04	GO:0031326	regulation of cellular biosynthetic process
1.23	6.42e-04	GO:0065008	regulation of biological quality
1.50	7.36e-04	GO:0006935	chemotaxis
1.50	7.36e-04	GO:0042330	taxis
1.68	1.04e-03	GO:0001817	regulation of cytokine production
1.43	1.38e-03	GO:0071310	cellular response to organic substance
1.20	1.42e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.11	1.49e-03	GO:0044238	primary metabolic process
1.20	2.07e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.47	2.20e-03	GO:0080134	regulation of response to stress
1.20	2.40e-03	GO:0010468	regulation of gene expression
1.30	2.43e-03	GO:0050790	regulation of catalytic activity
1.98	2.45e-03	GO:0045089	positive regulation of innate immune response
1.25	2.66e-03	GO:0009059	macromolecule biosynthetic process
1.33	4.17e-03	GO:0009605	response to external stimulus
1.24	4.82e-03	GO:0016070	RNA metabolic process
1.24	5.05e-03	GO:0034645	cellular macromolecule biosynthetic process
1.35	5.17e-03	GO:0016310	phosphorylation
1.67	5.89e-03	GO:0030097	hemopoiesis
1.21	6.04e-03	GO:0090304	nucleic acid metabolic process
1.21	7.01e-03	GO:0048523	negative regulation of cellular process
1.59	8.14e-03	GO:0034097	response to cytokine stimulus
2.33	8.63e-03	GO:0031294	lymphocyte costimulation
2.33	8.63e-03	GO:0031295	T cell costimulation
1.36	8.66e-03	GO:0007155	cell adhesion
1.36	8.66e-03	GO:0022610	biological adhesion
1.53	8.77e-03	GO:0044419	interspecies interaction between organisms
1.35	8.89e-03	GO:0044093	positive regulation of molecular function
1.59	9.36e-03	GO:0019932	second-messenger-mediated signaling
2.05	1.01e-02	GO:0030098	lymphocyte differentiation
1.18	1.03e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.80	1.03e-02	GO:0051272	positive regulation of cellular component movement
1.60	1.06e-02	GO:0051345	positive regulation of hydrolase activity
1.32	1.09e-02	GO:0070887	cellular response to chemical stimulus
1.61	1.19e-02	GO:0048534	hemopoietic or lymphoid organ development
1.82	1.27e-02	GO:0030335	positive regulation of cell migration
1.82	1.27e-02	GO:2000147	positive regulation of cell motility
2.33	1.37e-02	GO:0050864	regulation of B cell activation
1.17	1.39e-02	GO:0051171	regulation of nitrogen compound metabolic process
1.78	1.40e-02	GO:0031349	positive regulation of defense response
1.89	1.44e-02	GO:0002521	leukocyte differentiation
2.55	1.48e-02	GO:0002274	myeloid leukocyte activation
1.09	1.65e-02	GO:0008152	metabolic process
1.80	1.75e-02	GO:0040017	positive regulation of locomotion
1.33	1.80e-02	GO:0009891	positive regulation of biosynthetic process
1.74	1.98e-02	GO:0045088	regulation of innate immune response
1.30	2.17e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.35	2.23e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.28	2.41e-02	GO:0010604	positive regulation of macromolecule metabolic process
1.79	2.56e-02	GO:0050900	leukocyte migration
1.36	2.76e-02	GO:0019220	regulation of phosphate metabolic process
1.36	2.76e-02	GO:0051174	regulation of phosphorus metabolic process
1.61	2.95e-02	GO:0000165	MAPKKK cascade
2.25	3.01e-02	GO:0030217	T cell differentiation
2.01	3.20e-02	GO:0002758	innate immune response-activating signal transduction
1.40	3.53e-02	GO:0006928	cellular component movement
2.35	3.59e-02	GO:0045580	regulation of T cell differentiation
2.63	3.61e-02	GO:0030888	regulation of B cell proliferation
2.02	3.63e-02	GO:0002221	pattern recognition receptor signaling pathway
1.38	3.65e-02	GO:0009725	response to hormone stimulus
1.40	3.69e-02	GO:0051336	regulation of hydrolase activity
2.56	3.76e-02	GO:0050871	positive regulation of B cell activation
1.34	3.87e-02	GO:0016192	vesicle-mediated transport
1.34	3.99e-02	GO:2000026	regulation of multicellular organismal development
1.95	4.38e-02	GO:0050670	regulation of lymphocyte proliferation
1.26	4.54e-02	GO:0009893	positive regulation of metabolic process
1.55	4.55e-02	GO:0002520	immune system development

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	5.18e-07	GO:0044459	plasma membrane part
1.14	3.27e-04	GO:0005886	plasma membrane
1.14	6.08e-04	GO:0071944	cell periphery
1.47	9.17e-04	GO:0005768	endosome
1.21	1.36e-03	GO:0005829	cytosol
1.05	2.43e-03	GO:0005622	intracellular
1.08	2.96e-03	GO:0005737	cytoplasm
1.05	3.31e-03	GO:0044424	intracellular part
1.26	4.06e-03	GO:0005887	integral to plasma membrane
1.81	4.52e-03	GO:0009897	external side of plasma membrane
1.24	1.92e-02	GO:0031226	intrinsic to plasma membrane
1.30	2.45e-02	GO:0031982	vesicle
1.29	3.08e-02	GO:0005615	extracellular space
3.74	3.90e-02	GO:0042101	T cell receptor complex
1.42	3.98e-02	GO:0009986	cell surface
1.29	4.28e-02	GO:0031410	cytoplasmic vesicle
1.82	4.36e-02	GO:0005924	cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.19	3.30e-20	GO:0005515	protein binding
1.09	2.45e-15	GO:0005488	binding
1.40	1.23e-06	GO:0001071	nucleic acid binding transcription factor activity
1.40	1.23e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.68	1.59e-04	GO:0032403	protein complex binding
2.74	1.21e-03	GO:0003823	antigen binding
2.60	1.42e-03	GO:0008009	chemokine activity
2.45	3.81e-03	GO:0042379	chemokine receptor binding
1.35	4.34e-03	GO:0019899	enzyme binding
2.25	1.20e-02	GO:0035591	signaling adaptor activity
1.85	1.55e-02	GO:0030674	protein binding, bridging
1.81	1.86e-02	GO:0060090	binding, bridging
2.34	2.29e-02	GO:0005070	SH3/SH2 adaptor activity