Motif ID: FEV.p2

Z-value: 1.782


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_2198502730.484.3e-14Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_6798419 46.096 ZNF384
zinc finger protein 384
chr12_-_6798619 45.236 NM_001039920
NM_001135734
 ZNF384

zinc finger protein 384

chr11_+_61129831 36.560 TMEM138
transmembrane protein 138
chr11_-_46722160 35.841 ARHGAP1
Rho GTPase activating protein 1
chr12_-_6798528 35.535 NM_133476
 ZNF384
zinc finger protein 384
chr16_-_31085503 34.584 NM_024706
 ZNF668
zinc finger protein 668
chr11_+_46722564 30.667 NM_001184751
 ZNF408
zinc finger protein 408
chr16_+_31085722 29.201 NM_014699
 ZNF646
zinc finger protein 646
chr11_+_61197574 28.782 NM_017841
 SDHAF2
succinate dehydrogenase complex assembly factor 2
chr16_+_31085751 28.527 ZNF646
zinc finger protein 646
chr11_-_46722139 27.837 ARHGAP1
Rho GTPase activating protein 1
chr18_-_72264808 26.085 LOC400657
uncharacterized LOC400657
chr11_+_46722316 25.633 NM_024741
 ZNF408
zinc finger protein 408
chr3_-_121379701 24.580 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_121379757 24.376 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr8_-_38034168 24.187 LSM1
LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_+_17935379 23.695 NM_001130009
 GEN1
Gen endonuclease homolog 1 (Drosophila)
chr16_-_31085073 23.283 ZNF668
zinc finger protein 668
chr18_-_72265038 23.277 LOC400657
uncharacterized LOC400657
chr14_+_69865095 22.703 NM_001252151
NM_001252152
 SLC39A9

solute carrier family 39 (zinc transporter), member 9


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 154 entries
enrichment   p-value GO term description
2.63 3.61e-02 GO:0030888 regulation of B cell proliferation
2.56 3.76e-02 GO:0050871 positive regulation of B cell activation
2.55 1.48e-02 GO:0002274 myeloid leukocyte activation
2.52 2.31e-07 GO:0050851 antigen receptor-mediated signaling pathway
2.46 5.87e-05 GO:0050852 T cell receptor signaling pathway
2.38 8.85e-07 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.37 2.21e-06 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.35 3.59e-02 GO:0045580 regulation of T cell differentiation
2.33 8.63e-03 GO:0031294 lymphocyte costimulation
2.33 8.63e-03 GO:0031295 T cell costimulation
2.33 1.37e-02 GO:0050864 regulation of B cell activation
2.28 6.30e-11 GO:0002764 immune response-regulating signaling pathway
2.28 1.55e-10 GO:0002757 immune response-activating signal transduction
2.25 3.01e-02 GO:0030217 T cell differentiation
2.24 1.00e-04 GO:0007202 activation of phospholipase C activity
2.23 5.95e-05 GO:0010518 positive regulation of phospholipase activity
2.22 1.46e-04 GO:0010863 positive regulation of phospholipase C activity
2.20 1.13e-06 GO:0050870 positive regulation of T cell activation
2.18 7.26e-05 GO:0060193 positive regulation of lipase activity
2.17 1.13e-04 GO:0010517 regulation of phospholipase activity

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
3.74 3.90e-02 GO:0042101 T cell receptor complex
1.82 4.36e-02 GO:0005924 cell-substrate adherens junction
1.81 4.52e-03 GO:0009897 external side of plasma membrane
1.47 9.17e-04 GO:0005768 endosome
1.42 3.98e-02 GO:0009986 cell surface
1.30 2.45e-02 GO:0031982 vesicle
1.29 3.08e-02 GO:0005615 extracellular space
1.29 4.28e-02 GO:0031410 cytoplasmic vesicle
1.26 5.18e-07 GO:0044459 plasma membrane part
1.26 4.06e-03 GO:0005887 integral to plasma membrane
1.24 1.92e-02 GO:0031226 intrinsic to plasma membrane
1.21 1.36e-03 GO:0005829 cytosol
1.14 3.27e-04 GO:0005886 plasma membrane
1.14 6.08e-04 GO:0071944 cell periphery
1.08 2.96e-03 GO:0005737 cytoplasm
1.05 2.43e-03 GO:0005622 intracellular
1.05 3.31e-03 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.74 1.21e-03 GO:0003823 antigen binding
2.60 1.42e-03 GO:0008009 chemokine activity
2.45 3.81e-03 GO:0042379 chemokine receptor binding
2.34 2.29e-02 GO:0005070 SH3/SH2 adaptor activity
2.25 1.20e-02 GO:0035591 signaling adaptor activity
1.85 1.55e-02 GO:0030674 protein binding, bridging
1.81 1.86e-02 GO:0060090 binding, bridging
1.68 1.59e-04 GO:0032403 protein complex binding
1.40 1.23e-06 GO:0001071 nucleic acid binding transcription factor activity
1.40 1.23e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.35 4.34e-03 GO:0019899 enzyme binding
1.19 3.30e-20 GO:0005515 protein binding
1.09 2.45e-15 GO:0005488 binding