Motif ID: FOSL2.p2

Z-value: 2.025


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
FOSL2 2355 FOS-like antigen 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOSL2chr2_+_286163600.341.8e-07Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_22758538 91.407


chr22_+_22735134 90.076 CYAT1
immunoglobulin lambda light chain-like
chr22_+_23040394 83.849 IGL@
immunoglobulin lambda locus
chr2_-_89292396 72.515 IGKC
immunoglobulin kappa constant
chr22_+_22569155 65.977


chr2_-_89442551 65.191 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr22_+_22735207 60.774 IGLJ3
immunoglobulin lambda joining 3
chr2_-_89513056 55.308 IGKC
immunoglobulin kappa constant
chr7_+_30960914 52.900 NM_001185060
NM_001185061
NM_001185062
 AQP1


aquaporin 1 (Colton blood group)


chr7_+_23286386 52.672 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286277 52.654 NM_001005340
NM_002510
 GPNMB

glycoprotein (transmembrane) nmb

chr7_+_23286384 51.291 GPNMB
glycoprotein (transmembrane) nmb
chr22_+_22723972 50.903


chr7_+_23286390 50.776 GPNMB
glycoprotein (transmembrane) nmb
chr6_+_33043702 50.695 NM_002121
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr22_+_23165273 48.614


chr2_-_89619820 45.614 IGKC
immunoglobulin kappa constant
chr7_+_23286420 40.370 GPNMB
glycoprotein (transmembrane) nmb
chr12_-_15114495 37.832 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr22_+_22735202 34.929



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 86 entries
enrichment   p-value GO term description
8.06 4.13e-03 GO:0030513 positive regulation of BMP signaling pathway
4.27 1.55e-02 GO:0032680 regulation of tumor necrosis factor production
4.12 4.92e-03 GO:0060326 cell chemotaxis
3.63 6.02e-07 GO:0032496 response to lipopolysaccharide
3.54 3.75e-02 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
3.42 1.65e-02 GO:0002576 platelet degranulation
3.40 1.80e-06 GO:0002237 response to molecule of bacterial origin
3.24 2.07e-02 GO:0050730 regulation of peptidyl-tyrosine phosphorylation
2.92 6.89e-04 GO:0030335 positive regulation of cell migration
2.92 6.89e-04 GO:2000147 positive regulation of cell motility
2.82 1.43e-03 GO:0040017 positive regulation of locomotion
2.73 2.85e-03 GO:0051272 positive regulation of cellular component movement
2.53 1.36e-04 GO:0009617 response to bacterium
2.50 1.93e-04 GO:0030334 regulation of cell migration
2.49 3.17e-04 GO:0050865 regulation of cell activation
2.49 2.70e-02 GO:0051251 positive regulation of lymphocyte activation
2.47 2.73e-04 GO:2000145 regulation of cell motility
2.45 9.53e-04 GO:0002694 regulation of leukocyte activation
2.41 6.05e-03 GO:0051249 regulation of lymphocyte activation
2.40 3.16e-03 GO:0030168 platelet activation

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
3.63 2.79e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.49 4.20e-02 GO:0031983 vesicle lumen
2.81 5.23e-03 GO:0044420 extracellular matrix part
2.57 1.23e-04 GO:0030141 stored secretory granule
2.48 2.42e-02 GO:0043235 receptor complex
2.12 8.33e-04 GO:0005578 proteinaceous extracellular matrix
2.09 1.99e-04 GO:0031012 extracellular matrix
2.01 5.62e-09 GO:0005615 extracellular space
1.94 1.66e-10 GO:0044421 extracellular region part
1.59 4.75e-05 GO:0031226 intrinsic to plasma membrane
1.59 5.27e-05 GO:0005887 integral to plasma membrane
1.51 5.64e-07 GO:0005576 extracellular region
1.50 2.40e-07 GO:0044459 plasma membrane part
1.28 4.96e-05 GO:0005886 plasma membrane
1.27 1.05e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
3.04 3.84e-05 GO:0004252 serine-type endopeptidase activity
2.94 4.47e-03 GO:0019955 cytokine binding
2.78 1.88e-05 GO:0005529 sugar binding
2.71 3.17e-04 GO:0008236 serine-type peptidase activity
2.68 4.48e-02 GO:0019838 growth factor binding
2.67 4.70e-04 GO:0017171 serine hydrolase activity
2.44 9.06e-08 GO:0030246 carbohydrate binding
2.43 4.68e-03 GO:0005126 cytokine receptor binding
2.38 2.97e-02 GO:0001871 pattern binding
2.38 2.97e-02 GO:0030247 polysaccharide binding
2.14 6.03e-03 GO:0032403 protein complex binding
1.92 1.32e-02 GO:0004175 endopeptidase activity
1.60 9.65e-04 GO:0005102 receptor binding
1.53 1.42e-02 GO:0001071 nucleic acid binding transcription factor activity
1.53 1.42e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 9.11e-05 GO:0005515 protein binding
1.10 9.35e-05 GO:0005488 binding