Motif ID: FOXD3.p2

Z-value: 2.035


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD3chr1_+_63788729-0.551.7e-18Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_123234462 98.392 STAG2
stromal antigen 2
chr5_+_159436143 91.677 TTC1
tetratricopeptide repeat domain 1
chr11_-_16996559 86.757 RPL36A
ribosomal protein L36a
chr11_-_67450536 80.088 RPL37
ribosomal protein L37
chr12_+_27175482 61.870 NM_004264
 MED21
mediator complex subunit 21
chr6_+_74171610 60.147 MTO1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr2_+_216176808 59.672 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_-_87849341 58.258 SRI
sorcin
chr4_+_146031528 56.972 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr2_-_47134945 56.556 MCFD2
multiple coagulation factor deficiency 2
chr14_+_102276125 53.752 NM_002719
NM_178586
NM_178587
 PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr3_+_172472246 52.583 NM_018098
 ECT2
epithelial cell transforming sequence 2 oncogene
chr2_+_216176678 52.046 NM_004044
 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_159436155 49.728 NM_003314
 TTC1
tetratricopeptide repeat domain 1
chr2_+_216176818 49.619 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr6_-_150057659 49.419 NUP43
nucleoporin 43kDa
chr22_-_43036606 47.743 NM_001165877
 ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_-_25683825 47.395 TOP2B
topoisomerase (DNA) II beta 180kDa
chr16_+_30064410 46.386 NM_000034
 ALDOA
aldolase A, fructose-bisphosphate
chr20_+_19870209 45.230 NM_018993
 RIN2
Ras and Rab interactor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 90 entries
enrichment   p-value GO term description
3.01 5.04e-07 GO:0000082 G1/S transition of mitotic cell cycle
2.64 9.07e-03 GO:0000077 DNA damage checkpoint
2.60 2.22e-03 GO:0007093 mitotic cell cycle checkpoint
2.59 1.31e-02 GO:0000084 S phase of mitotic cell cycle
2.54 1.88e-02 GO:0051320 S phase
2.47 3.17e-02 GO:0031570 DNA integrity checkpoint
2.42 3.00e-05 GO:0000075 cell cycle checkpoint
2.33 1.05e-04 GO:0071156 regulation of cell cycle arrest
2.29 1.39e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.29 1.39e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
2.23 2.84e-03 GO:0000375 RNA splicing, via transesterification reactions
2.18 3.39e-05 GO:0051329 interphase of mitotic cell cycle
2.18 4.91e-03 GO:0071843 cellular component biogenesis at cellular level
2.14 6.54e-05 GO:0051325 interphase
2.13 2.22e-02 GO:0022613 ribonucleoprotein complex biogenesis
2.10 2.86e-05 GO:0010564 regulation of cell cycle process
2.04 3.73e-03 GO:0007346 regulation of mitotic cell cycle
2.01 1.81e-03 GO:0008380 RNA splicing
1.97 1.23e-02 GO:0015980 energy derivation by oxidation of organic compounds
1.95 2.80e-03 GO:0043632 modification-dependent macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 32 entries
enrichment   p-value GO term description
10.74 3.43e-02 GO:0070552 BRISC complex
2.49 6.45e-04 GO:0005681 spliceosomal complex
2.04 5.68e-09 GO:0030529 ribonucleoprotein complex
1.73 3.10e-06 GO:0044451 nucleoplasm part
1.70 1.16e-11 GO:0005654 nucleoplasm
1.64 1.46e-17 GO:0044428 nuclear part
1.64 1.76e-14 GO:0031981 nuclear lumen
1.64 6.46e-03 GO:0005730 nucleolus
1.64 1.47e-02 GO:0044427 chromosomal part
1.59 3.48e-16 GO:0031974 membrane-enclosed lumen
1.58 1.25e-15 GO:0043233 organelle lumen
1.57 9.29e-15 GO:0070013 intracellular organelle lumen
1.56 2.62e-02 GO:0005694 chromosome
1.48 1.75e-18 GO:0032991 macromolecular complex
1.44 8.47e-08 GO:0005829 cytosol
1.40 5.25e-10 GO:0043234 protein complex
1.37 7.64e-21 GO:0044446 intracellular organelle part
1.36 3.06e-20 GO:0044422 organelle part
1.31 1.87e-14 GO:0005634 nucleus
1.29 5.46e-03 GO:0031090 organelle membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
4.07 1.96e-03 GO:0043130 ubiquitin binding
3.86 4.05e-03 GO:0032182 small conjugating protein binding
2.19 2.16e-02 GO:0003735 structural constituent of ribosome
2.06 3.29e-02 GO:0016758 transferase activity, transferring hexosyl groups
1.75 1.05e-07 GO:0003723 RNA binding
1.35 3.36e-31 GO:0005515 protein binding
1.21 2.01e-02 GO:0003676 nucleic acid binding
1.14 7.12e-17 GO:0005488 binding
1.14 3.70e-02 GO:0003824 catalytic activity