Motif ID: FOXL1.p2

Z-value: 1.118


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXL1chr16_+_866121140.391.7e-09Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_39899749 37.318


chr17_-_29641068 30.144 EVI2B
ecotropic viral integration site 2B
chr17_-_29641087 29.895 EVI2B
ecotropic viral integration site 2B
chr3_-_12941547 27.498 IQSEC1
IQ motif and Sec7 domain 1
chr17_-_29641094 23.831 NM_006495
 EVI2B
ecotropic viral integration site 2B
chr4_+_74269971 20.757 NM_000477
 ALB
albumin
chr4_-_71532206 16.693 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr4_-_71532341 15.111 NM_144646
 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_+_143886898 14.675 NM_018460
 ARHGAP15
Rho GTPase activating protein 15
chr7_+_80267972 14.404 CD36
CD36 molecule (thrombospondin receptor)
chr4_-_84035888 14.377 PLAC8
placenta-specific 8
chr1_+_198608136 13.467 NM_002838
NM_080921
NM_080923
 PTPRC


protein tyrosine phosphatase, receptor type, C


chr2_-_89165652 12.931


chr14_+_92788924 12.927 NM_153648
 SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr4_-_84035908 12.212 NM_001130715
NM_016619
 PLAC8

placenta-specific 8

chr12_+_69742140 12.133 LYZ
lysozyme
chrX_+_37639246 10.877 NM_000397
 CYBB
cytochrome b-245, beta polypeptide
chr2_+_143886969 10.531 ARHGAP15
Rho GTPase activating protein 15
chr14_+_21249209 10.245 NM_005615
 RNASE6
ribonuclease, RNase A family, k6
chr7_+_80267922 9.932 CD36
CD36 molecule (thrombospondin receptor)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 73 entries
enrichment   p-value GO term description
7.05 1.71e-02 GO:0019835 cytolysis
6.50 7.23e-05 GO:0030049 muscle filament sliding
6.50 7.23e-05 GO:0033275 actin-myosin filament sliding
6.33 1.04e-04 GO:0070252 actin-mediated cell contraction
5.97 7.07e-03 GO:0006958 complement activation, classical pathway
5.81 3.03e-03 GO:0002455 humoral immune response mediated by circulating immunoglobulin
5.29 3.14e-03 GO:0006956 complement activation
4.85 2.09e-04 GO:0072376 protein activation cascade
4.72 4.78e-03 GO:0030048 actin filament-based movement
4.37 1.19e-02 GO:0016064 immunoglobulin mediated immune response
4.29 1.48e-02 GO:0019724 B cell mediated immunity
4.16 4.25e-04 GO:0006959 humoral immune response
4.02 7.03e-03 GO:0002449 lymphocyte mediated immunity
3.86 6.84e-04 GO:0051216 cartilage development
3.75 1.76e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
3.65 2.48e-02 GO:0002250 adaptive immune response
3.40 1.29e-05 GO:0006936 muscle contraction
3.33 6.12e-06 GO:0003012 muscle system process
2.95 2.70e-05 GO:0002253 activation of immune response
2.87 1.32e-06 GO:0050778 positive regulation of immune response

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
15.85 5.23e-05 GO:0005579 membrane attack complex
9.25 3.75e-05 GO:0032982 myosin filament
7.40 1.58e-03 GO:0016460 myosin II complex
7.19 7.89e-03 GO:0005859 muscle myosin complex
3.91 2.69e-02 GO:0031983 vesicle lumen
3.19 1.16e-03 GO:0030016 myofibril
3.16 7.82e-04 GO:0043292 contractile fiber
2.95 1.07e-02 GO:0044449 contractile fiber part
2.88 2.36e-23 GO:0005615 extracellular space
2.83 1.05e-29 GO:0044421 extracellular region part
2.72 2.59e-07 GO:0005578 proteinaceous extracellular matrix
2.56 2.49e-07 GO:0031012 extracellular matrix
2.11 3.18e-26 GO:0005576 extracellular region
2.06 2.84e-13 GO:0005887 integral to plasma membrane
2.02 1.23e-12 GO:0031226 intrinsic to plasma membrane
1.80 5.48e-15 GO:0044459 plasma membrane part
1.73 7.22e-04 GO:0005626 insoluble fraction
1.71 3.53e-05 GO:0000267 cell fraction
1.69 3.05e-03 GO:0005624 membrane fraction
1.49 6.15e-13 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
5.16 9.90e-04 GO:0008307 structural constituent of muscle
4.42 1.34e-02 GO:0008009 chemokine activity
3.99 3.73e-02 GO:0042379 chemokine receptor binding
3.62 1.72e-09 GO:0005125 cytokine activity
3.24 4.66e-02 GO:0005201 extracellular matrix structural constituent
2.98 6.17e-05 GO:0005126 cytokine receptor binding
2.00 4.72e-02 GO:0003779 actin binding
1.96 1.81e-04 GO:0005198 structural molecule activity
1.86 9.38e-07 GO:0005102 receptor binding
1.77 6.23e-03 GO:0005509 calcium ion binding
1.53 6.65e-03 GO:0004888 transmembrane receptor activity
1.49 1.21e-03 GO:0004872 receptor activity
1.41 3.90e-03 GO:0004871 signal transducer activity
1.41 3.90e-03 GO:0060089 molecular transducer activity