Motif ID: FOXN1.p2

Z-value: 1.643


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXN1chr17_+_26850958-0.622.6e-24Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_8938745 28.961 ENO1
enolase 1, (alpha)
chr1_-_8938727 26.185 ENO1
enolase 1, (alpha)
chr1_-_8939150 26.005 NM_001428
ENO1
enolase 1, (alpha)
chr14_+_52456322 23.692 C14orf166
chromosome 14 open reading frame 166
chr19_-_42806928 21.767 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr4_-_174255454 20.957 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr1_-_8938691 20.468 ENO1
enolase 1, (alpha)
chrX_-_153775427 20.380 G6PD
glucose-6-phosphate dehydrogenase
chr2_-_61764661 19.848 XPO1
exportin 1 (CRM1 homolog, yeast)
chr2_+_113403433 19.297 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr2_+_187351032 19.117 ZC3H15
zinc finger CCCH-type containing 15
chr15_-_23034307 19.105 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr1_+_44440595 18.947 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr18_+_29672568 18.813 NM_001191324
NM_198128
RNF138

ring finger protein 138

chr1_+_44440623 18.561 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr12_+_104609501 18.545 NM_001093771
TXNRD1
thioredoxin reductase 1
chr19_-_41859519 18.435 TGFB1
transforming growth factor, beta 1
chr4_-_1713914 17.842 NM_006527
SLBP
stem-loop binding protein
chr4_-_103748254 17.767 NM_181892
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr14_+_52456192 17.684 NM_016039
C14orf166
chromosome 14 open reading frame 166

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 93 entries
enrichment   p-value GO term description
19.78 1.41e-02 GO:0046796 viral genome transport in host cell
4.08 2.89e-02 GO:0031124 mRNA 3'-end processing
3.38 1.61e-06 GO:0000375 RNA splicing, via transesterification reactions
3.26 1.29e-05 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.26 1.29e-05 GO:0000398 nuclear mRNA splicing, via spliceosome
3.08 2.62e-02 GO:0006403 RNA localization
2.79 9.93e-06 GO:0008380 RNA splicing
2.75 9.92e-03 GO:0022411 cellular component disassembly
2.75 9.92e-03 GO:0071845 cellular component disassembly at cellular level
2.68 3.65e-02 GO:0006913 nucleocytoplasmic transport
2.65 1.54e-06 GO:0006397 mRNA processing
2.65 4.42e-02 GO:0051169 nuclear transport
2.60 7.88e-04 GO:0010608 posttranscriptional regulation of gene expression
2.59 5.53e-09 GO:0016071 mRNA metabolic process
2.59 2.85e-02 GO:0006457 protein folding
2.50 2.75e-03 GO:0032446 protein modification by small protein conjugation
2.48 3.76e-04 GO:0070647 protein modification by small protein conjugation or removal
2.46 2.05e-03 GO:0048285 organelle fission
2.44 1.34e-02 GO:0016567 protein ubiquitination
2.42 7.21e-07 GO:0044265 cellular macromolecule catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
7.69 6.01e-03 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
4.56 4.19e-02 GO:0005876 spindle microtubule
3.51 1.42e-02 GO:0071013 catalytic step 2 spliceosome
3.34 4.46e-02 GO:0000779 condensed chromosome, centromeric region
3.25 3.76e-04 GO:0005681 spliceosomal complex
3.15 4.80e-02 GO:0000776 kinetochore
2.70 2.84e-02 GO:0000793 condensed chromosome
2.65 4.77e-03 GO:0005819 spindle
2.59 1.03e-09 GO:0030529 ribonucleoprotein complex
2.26 4.78e-02 GO:0016604 nuclear body
2.19 4.55e-16 GO:0005654 nucleoplasm
2.07 9.57e-04 GO:0044427 chromosomal part
2.06 5.55e-19 GO:0031981 nuclear lumen
2.03 8.47e-04 GO:0005730 nucleolus
2.00 1.75e-21 GO:0070013 intracellular organelle lumen
1.99 4.33e-20 GO:0044428 nuclear part
1.98 6.46e-03 GO:0005768 endosome
1.96 2.26e-20 GO:0043233 organelle lumen
1.96 1.09e-03 GO:0005694 chromosome
1.95 1.31e-20 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.67 3.28e-04 GO:0019787 small conjugating protein ligase activity
2.50 6.26e-04 GO:0016881 acid-amino acid ligase activity
2.46 7.62e-03 GO:0004842 ubiquitin-protein ligase activity
2.39 8.97e-04 GO:0016879 ligase activity, forming carbon-nitrogen bonds
2.20 9.94e-05 GO:0016874 ligase activity
2.18 3.15e-09 GO:0003723 RNA binding
1.84 6.27e-04 GO:0019899 enzyme binding
1.69 2.48e-02 GO:0017111 nucleoside-triphosphatase activity
1.68 2.15e-02 GO:0016462 pyrophosphatase activity
1.67 2.43e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.66 2.73e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.56 8.27e-07 GO:0000166 nucleotide binding
1.49 1.58e-29 GO:0005515 protein binding
1.49 8.52e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.47 1.66e-03 GO:0017076 purine nucleotide binding
1.47 2.01e-03 GO:0032553 ribonucleotide binding
1.47 2.01e-03 GO:0032555 purine ribonucleotide binding
1.41 9.53e-06 GO:0003676 nucleic acid binding
1.26 5.80e-04 GO:0003824 catalytic activity
1.18 3.95e-12 GO:0005488 binding