Motif ID: FOXO1,3,4.p2

Z-value: 1.208


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXO4chrX_+_703156370.504.7e-15Click!
FOXO3chr6_+_1088821040.357.9e-08Click!
FOXO1chr13_-_412406070.221.2e-03Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_57044980 36.892 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_57045235 31.880 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_9268440 29.691 A2M
alpha-2-macroglobulin
chr12_-_9268522 28.439 NM_000014
 A2M
alpha-2-macroglobulin
chr12_-_9268513 28.231 A2M
alpha-2-macroglobulin
chr5_-_42811959 26.021 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr1_-_57045129 25.401 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_9268475 21.227 A2M
alpha-2-macroglobulin
chr4_-_88450601 19.344 NM_001128310
NM_004684
 SPARCL1

SPARC-like 1 (hevin)

chr8_-_110655418 17.946 NM_001099756
 SYBU
syntabulin (syntaxin-interacting)
chr1_-_57045214 17.602 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_182360889 17.550 GLUL
glutamate-ammonia ligase
chr4_-_88450243 17.308 SPARCL1
SPARC-like 1 (hevin)
chr17_+_1665306 15.753 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1665233 15.180 NM_002615
 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr22_+_33196801 14.903 NM_000362
 TIMP3
TIMP metallopeptidase inhibitor 3
chr1_-_182360181 14.515 GLUL
glutamate-ammonia ligase
chr14_-_21271002 13.881 NM_002933
NM_198234
NM_198235
 RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr14_+_94577078 12.817 NM_001130080
NM_005532
 IFI27

interferon, alpha-inducible protein 27

chr1_-_182360400 12.587 NM_001033056
 GLUL
glutamate-ammonia ligase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
3.85 1.12e-02 GO:0045444 fat cell differentiation
2.45 3.14e-02 GO:0006936 muscle contraction
1.61 1.56e-02 GO:0040011 locomotion
1.58 9.57e-03 GO:0009605 response to external stimulus
1.45 1.39e-02 GO:0009653 anatomical structure morphogenesis
1.42 2.44e-04 GO:0042221 response to chemical stimulus
1.40 1.80e-03 GO:0048869 cellular developmental process
1.38 9.59e-03 GO:0030154 cell differentiation
1.37 3.48e-02 GO:0048583 regulation of response to stimulus
1.35 3.94e-06 GO:0023052 signaling
1.31 1.01e-03 GO:0007165 signal transduction
1.30 6.17e-03 GO:0048856 anatomical structure development
1.29 8.25e-07 GO:0032501 multicellular organismal process
1.29 3.37e-02 GO:0048731 system development
1.26 7.25e-03 GO:0032502 developmental process
1.26 2.62e-02 GO:0007275 multicellular organismal development
1.24 1.51e-02 GO:0051716 cellular response to stimulus
1.19 4.21e-03 GO:0050896 response to stimulus
1.14 3.10e-02 GO:0065007 biological regulation
1.13 2.32e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.08 4.99e-02 GO:0030141 stored secretory granule
1.60 4.68e-03 GO:0005615 extracellular space
1.56 8.70e-05 GO:0005887 integral to plasma membrane
1.56 1.10e-03 GO:0044421 extracellular region part
1.55 1.41e-04 GO:0031226 intrinsic to plasma membrane
1.47 1.33e-06 GO:0044459 plasma membrane part
1.39 4.20e-04 GO:0005576 extracellular region

Nothing significant found in function category.