Motif ID: FOXP3.p2

Z-value: 1.807


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXP3chrX_-_491211710.704.5e-33Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_29641068 56.464 EVI2B
ecotropic viral integration site 2B
chr1_-_93399531 56.125


chr6_+_88117689 51.843 NM_001031743
 C6orf165
chromosome 6 open reading frame 165
chr6_-_32497925 36.128 NM_002125
 HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr22_+_21986968 35.315 NM_152612
 CCDC116
coiled-coil domain containing 116
chr16_-_70099755 35.017 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr18_-_74728963 29.932 MBP
myelin basic protein
chr1_-_153029987 28.997 NM_005988
 SPRR2A
small proline-rich protein 2A
chr18_-_74729049 28.069 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein



chr5_+_140213968 25.856 NM_018910
NM_031852
 PCDHA7

protocadherin alpha 7

chr1_+_15990300 25.677


chr11_+_124824076 25.112 CCDC15
coiled-coil domain containing 15
chr16_+_31085722 24.443 NM_014699
 ZNF646
zinc finger protein 646
chr1_+_66798095 24.148 PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_62475165 23.992 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr11_+_62475113 23.890 NM_012202
 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chrX_-_100641143 23.673 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chr17_-_29641087 23.018 EVI2B
ecotropic viral integration site 2B
chr1_-_153044083 22.635 NM_001017418
 SPRR2B
small proline-rich protein 2B
chrX_+_103031797 22.602 PLP1
proteolipid protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 39 entries
enrichment   p-value GO term description
13.99 2.68e-02 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
7.93 3.26e-02 GO:0006956 complement activation
6.92 2.41e-02 GO:0016064 immunoglobulin mediated immune response
6.80 2.77e-02 GO:0019724 B cell mediated immunity
6.60 3.31e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
6.35 5.48e-05 GO:0002768 immune response-regulating cell surface receptor signaling pathway
5.95 8.79e-03 GO:0006959 humoral immune response
5.79 3.20e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
5.64 3.97e-02 GO:0002250 adaptive immune response
5.63 5.26e-03 GO:0050851 antigen receptor-mediated signaling pathway
4.69 6.14e-06 GO:0002253 activation of immune response
4.39 8.21e-07 GO:0050778 positive regulation of immune response
4.18 4.45e-03 GO:0002757 immune response-activating signal transduction
4.08 5.92e-03 GO:0002764 immune response-regulating signaling pathway
4.06 6.35e-03 GO:0002696 positive regulation of leukocyte activation
4.06 1.29e-02 GO:0051251 positive regulation of lymphocyte activation
3.99 7.81e-03 GO:0050867 positive regulation of cell activation
3.91 1.21e-03 GO:0008202 steroid metabolic process
3.81 6.05e-08 GO:0050776 regulation of immune response
3.50 3.67e-06 GO:0002684 positive regulation of immune system process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
13.59 3.38e-02 GO:0042613 MHC class II protein complex
3.05 2.76e-02 GO:0005792 microsome
2.95 3.99e-02 GO:0042598 vesicular fraction
2.68 1.16e-06 GO:0005615 extracellular space
2.29 3.54e-04 GO:0005626 insoluble fraction
2.24 1.11e-03 GO:0005624 membrane fraction
2.21 9.33e-05 GO:0044421 extracellular region part
2.10 7.69e-05 GO:0005887 integral to plasma membrane
2.07 1.10e-08 GO:0005576 extracellular region
2.07 6.01e-04 GO:0000267 cell fraction
2.06 1.36e-04 GO:0031226 intrinsic to plasma membrane
1.87 3.39e-06 GO:0044459 plasma membrane part
1.74 7.02e-11 GO:0005886 plasma membrane
1.73 9.86e-11 GO:0071944 cell periphery
1.39 3.51e-04 GO:0031224 intrinsic to membrane
1.39 5.27e-04 GO:0016021 integral to membrane
1.35 2.81e-04 GO:0044425 membrane part
1.33 1.69e-05 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.09 9.73e-05 GO:0004888 transmembrane receptor activity
1.95 1.64e-02 GO:0005102 receptor binding
1.93 6.04e-05 GO:0004872 receptor activity
1.68 3.61e-03 GO:0004871 signal transducer activity
1.68 3.61e-03 GO:0060089 molecular transducer activity