Motif ID: GATA1..3.p2

Z-value: 2.415


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
GATA1 2623 GATA binding protein 1 (globin transcription factor 1)
GATA2 2624 GATA binding protein 2
GATA3 2625 GATA binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GATA2chr3_-_1282067040.276.1e-05Click!
GATA1chrX_+_48644961-0.126.9e-02Click!
GATA3chr10_+_8097350-0.111.1e-01Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_91769329 62.850 SV2B
synaptic vesicle glycoprotein 2B
chrX_+_38420690 42.645 NM_004615
 TSPAN7
tetraspanin 7
chr5_-_141993691 40.447 NM_033137
 FGF1
fibroblast growth factor 1 (acidic)
chr19_+_54376975 37.790 MYADM
myeloid-associated differentiation marker
chr12_+_79258588 36.835 SYT1
synaptotagmin I
chr5_+_156820161 35.930 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_111782447 33.257 NM_001885
 CRYAB
crystallin, alpha B
chrX_-_13835187 32.776 GPM6B
glycoprotein M6B
chr6_-_32095974 31.717 ATF6B
activating transcription factor 6 beta
chr12_+_79258517 31.405 SYT1
synaptotagmin I
chr14_+_65007418 30.953 HSPA2
heat shock 70kDa protein 2
chr7_-_31380507 30.734 NM_022728
 NEUROD6
neurogenic differentiation 6
chr6_-_32095993 30.560 NM_001136153
NM_004381
 ATF6B

activating transcription factor 6 beta

chr3_-_195310985 30.004 NM_001647
 APOD
apolipoprotein D
chr2_+_149632772 28.198 NM_004522
 KIF5C
kinesin family member 5C
chr3_+_133494275 27.871 TF
transferrin
chrX_-_153236621 27.318 NM_005334
 HCFC1
host cell factor C1 (VP16-accessory protein)
chr4_+_76439653 26.594 NM_144721
 THAP6
THAP domain containing 6
chrX_-_13835012 25.195 GPM6B
glycoprotein M6B
chr12_+_79258448 24.584 NM_005639
 SYT1
synaptotagmin I

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 168 entries
enrichment   p-value GO term description
4.18 2.09e-04 GO:0021795 cerebral cortex cell migration
3.92 4.02e-05 GO:0022029 telencephalon cell migration
3.75 1.26e-04 GO:0021885 forebrain cell migration
3.72 4.61e-02 GO:0014047 glutamate secretion
3.32 2.11e-03 GO:0007632 visual behavior
2.95 1.33e-04 GO:0003073 regulation of systemic arterial blood pressure
2.86 1.86e-03 GO:0021987 cerebral cortex development
2.66 1.64e-02 GO:0051899 membrane depolarization
2.28 1.03e-03 GO:0008016 regulation of heart contraction
2.16 1.37e-05 GO:0042391 regulation of membrane potential
2.14 7.19e-04 GO:0006836 neurotransmitter transport
2.12 1.77e-03 GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger
2.09 1.06e-02 GO:0021537 telencephalon development
2.08 1.66e-02 GO:0001505 regulation of neurotransmitter levels
2.07 1.67e-03 GO:0019933 cAMP-mediated signaling
2.02 2.12e-17 GO:0007268 synaptic transmission
2.01 7.32e-03 GO:0003001 generation of a signal involved in cell-cell signaling
2.01 7.32e-03 GO:0023061 signal release
2.00 6.52e-31 GO:0007267 cell-cell signaling
1.99 9.94e-19 GO:0019226 transmission of nerve impulse

Gene overrepresentation in compartment category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
3.14 1.61e-02 GO:0005891 voltage-gated calcium channel complex
2.80 1.44e-02 GO:0034704 calcium channel complex
2.62 4.25e-02 GO:0043204 perikaryon
2.47 7.19e-06 GO:0033267 axon part
2.33 1.34e-02 GO:0044309 neuron spine
2.33 2.16e-02 GO:0043197 dendritic spine
2.08 4.12e-08 GO:0030424 axon
2.05 9.78e-04 GO:0019717 synaptosome
2.03 2.39e-05 GO:0034703 cation channel complex
1.99 2.61e-16 GO:0043005 neuron projection
1.98 3.97e-16 GO:0045202 synapse
1.95 4.87e-05 GO:0045211 postsynaptic membrane
1.94 1.35e-06 GO:0030425 dendrite
1.93 3.55e-02 GO:0008021 synaptic vesicle
1.92 2.68e-10 GO:0044456 synapse part
1.85 1.36e-04 GO:0043025 neuronal cell body
1.83 1.34e-05 GO:0034702 ion channel complex
1.80 4.36e-04 GO:0044297 cell body
1.57 1.60e-12 GO:0042995 cell projection
1.57 2.83e-05 GO:0044463 cell projection part

Gene overrepresentation in function category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
3.81 3.16e-03 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
3.38 8.25e-04 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
3.25 1.87e-03 GO:0004112 cyclic-nucleotide phosphodiesterase activity
1.96 1.92e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
1.93 3.31e-04 GO:0022843 voltage-gated cation channel activity
1.90 9.85e-04 GO:0005516 calmodulin binding
1.78 1.94e-04 GO:0000975 regulatory region DNA binding
1.78 1.94e-04 GO:0001067 regulatory region nucleic acid binding
1.78 1.94e-04 GO:0044212 transcription regulatory region DNA binding
1.78 3.95e-04 GO:0010843 promoter binding
1.70 8.92e-06 GO:0022836 gated channel activity
1.69 1.13e-04 GO:0005261 cation channel activity
1.66 2.11e-02 GO:0005244 voltage-gated ion channel activity
1.66 2.11e-02 GO:0022832 voltage-gated channel activity
1.65 5.75e-07 GO:0015267 channel activity
1.65 6.89e-07 GO:0022803 passive transmembrane transporter activity
1.60 1.75e-05 GO:0022838 substrate-specific channel activity
1.60 2.42e-05 GO:0005216 ion channel activity
1.52 6.55e-12 GO:0005102 receptor binding
1.50 7.54e-07 GO:0043565 sequence-specific DNA binding