Motif ID: GAUUGUC

Z-value: 1.021


Mature miRNA associated with seed GAUUGUC:

NamemiRBase Accession
hsa-miR-219-5p MIMAT0000276
hsa-miR-4782-3p MIMAT0019945



Activity profile for motif GAUUGUC.

activity profile for motif GAUUGUC


Sorted Z-values histogram for motif GAUUGUC

Sorted Z-values for motif GAUUGUC



Network of associatons between targets according to the STRING database.



First level regulatory network of GAUUGUC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_167298280 13.210 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr16_+_85646923 13.038 NM_014615
 KIAA0182
KIAA0182
chr16_+_85645014 12.751 NM_001134473
 KIAA0182
KIAA0182
chr6_+_47445440 12.744 NM_012120
 CD2AP
CD2-associated protein
chr4_-_109089444 11.771 NM_001130713
NM_001130714
NM_016269
 LEF1


lymphoid enhancer-binding factor 1


chr17_-_29151724 11.238 NM_015986
 CRLF3
cytokine receptor-like factor 3
chr16_-_89007605 9.865 NM_175931
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_-_89043215 9.692 NM_005187
 CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_-_109087876 9.364 NM_001166119
 LEF1
lymphoid enhancer-binding factor 1
chr7_+_101460881 8.999 NM_181552
 CUX1
cut-like homeobox 1
chr5_+_112312392 8.847 NM_001242377
NM_152624
 DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr1_+_167189948 8.729 NM_001198786
NM_002697
 POU2F1

POU class 2 homeobox 1

chr15_-_61521478 8.688 NM_134261
 RORA
RAR-related orphan receptor A
chr4_+_38665587 8.508 NM_016531
 KLF3
Kruppel-like factor 3 (basic)
chr15_-_60884615 8.445 NM_134262
 RORA
RAR-related orphan receptor A
chr3_+_187871473 8.435 NM_001167672
 LPP
LIM domain containing preferred translocation partner in lipoma
chr15_-_60919642 7.761 NM_002943
NM_134260
 RORA

RAR-related orphan receptor A

chr12_-_56652118 7.726 NM_173595
 ANKRD52
ankyrin repeat domain 52
chr3_+_187943192 7.582 NM_001167671
 LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_2985730 7.203 NM_022114
NM_199454
 PRDM16

PR domain containing 16


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 59 entries
enrichment   p-value GO term description
12.81 3.91e-02 GO:0030850 prostate gland development
12.22 2.61e-04 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
4.93 1.17e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
4.31 1.11e-02 GO:0007423 sensory organ development
4.25 2.60e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
4.16 1.70e-04 GO:0032583 regulation of gene-specific transcription
3.88 6.96e-06 GO:0045893 positive regulation of transcription, DNA-dependent
3.72 7.90e-06 GO:0010628 positive regulation of gene expression
3.61 2.80e-05 GO:0051254 positive regulation of RNA metabolic process
3.57 2.31e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.57 4.98e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.50 1.43e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
3.46 9.61e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
3.23 4.26e-05 GO:0031328 positive regulation of cellular biosynthetic process
3.22 4.44e-03 GO:0009887 organ morphogenesis
3.17 6.10e-05 GO:0009891 positive regulation of biosynthetic process
3.09 1.07e-04 GO:0006351 transcription, DNA-dependent
3.06 4.53e-02 GO:0045892 negative regulation of transcription, DNA-dependent
2.94 2.76e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.84 2.79e-02 GO:0031327 negative regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
2.49 7.52e-05 GO:0005654 nucleoplasm
2.16 1.93e-04 GO:0031981 nuclear lumen
1.96 9.80e-04 GO:0044428 nuclear part
1.89 2.66e-03 GO:0070013 intracellular organelle lumen
1.85 4.39e-03 GO:0043233 organelle lumen
1.82 6.57e-03 GO:0031974 membrane-enclosed lumen
1.60 9.53e-06 GO:0005634 nucleus
1.32 1.62e-03 GO:0043231 intracellular membrane-bounded organelle
1.32 1.73e-03 GO:0043227 membrane-bounded organelle
1.30 4.83e-04 GO:0043229 intracellular organelle
1.30 5.47e-04 GO:0043226 organelle
1.23 1.01e-03 GO:0044424 intracellular part
1.22 1.81e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
16.12 1.08e-07 GO:0004879 ligand-dependent nuclear receptor activity
15.37 1.28e-06 GO:0003707 steroid hormone receptor activity
5.61 1.37e-04 GO:0000975 regulatory region DNA binding
5.61 1.37e-04 GO:0001067 regulatory region nucleic acid binding
5.61 1.37e-04 GO:0044212 transcription regulatory region DNA binding
5.39 5.65e-04 GO:0010843 promoter binding
5.16 3.70e-02 GO:0003690 double-stranded DNA binding
4.75 2.74e-02 GO:0000287 magnesium ion binding
4.25 6.26e-03 GO:0003702 RNA polymerase II transcription factor activity
4.24 6.30e-04 GO:0016563 transcription activator activity
4.20 2.60e-09 GO:0043565 sequence-specific DNA binding
3.49 4.15e-02 GO:0016564 transcription repressor activity
3.47 5.72e-09 GO:0001071 nucleic acid binding transcription factor activity
3.47 5.72e-09 GO:0003700 sequence-specific DNA binding transcription factor activity
3.02 2.58e-06 GO:0030528 transcription regulator activity
1.84 5.64e-03 GO:0003677 DNA binding
1.72 1.54e-03 GO:0003676 nucleic acid binding
1.52 5.93e-07 GO:0005515 protein binding
1.23 2.15e-04 GO:0005488 binding