Motif ID: GCUACAU

Z-value: 0.685


Mature miRNA associated with seed GCUACAU:

NamemiRBase Accession
hsa-miR-221 MIMAT0000278
hsa-miR-222 MIMAT0000279



Activity profile for motif GCUACAU.

activity profile for motif GCUACAU


Sorted Z-values histogram for motif GCUACAU

Sorted Z-values for motif GCUACAU



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUACAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_176923572 11.623 NM_005277
NM_201592
 GPM6A

glycoprotein M6A

chr4_-_176734181 10.979 NM_201591
 GPM6A
glycoprotein M6A
chr12_+_12869818 9.150 NM_004064
 CDKN1B
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr1_+_169075869 8.760 NM_001677
 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_-_41131323 7.479 NM_014747
 RIMS3
regulating synaptic membrane exocytosis 3
chr16_+_15596122 6.787 NM_001142469
 C16orf45
chromosome 16 open reading frame 45
chr5_+_161277702 6.357 NM_001127648
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161274196 6.157 NM_000806
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr16_+_15528324 6.114 NM_033201
 C16orf45
chromosome 16 open reading frame 45
chr5_+_141488314 6.071 NM_030571
 NDFIP1
Nedd4 family interacting protein 1
chr12_-_118498893 5.801 NM_018639
 WSB2
WD repeat and SOCS box containing 2
chr5_+_161275541 5.600 NM_001127645
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161274684 5.572 NM_001127643
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161277391 5.480 NM_001127647
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_161274939 5.325 NM_001127644
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_-_176057324 4.920 NM_001001502
NM_003085
 SNCB

synuclein, beta

chr5_+_161275897 4.500 NM_001127646
 GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_+_140345746 4.369 NM_018899
 PCDHAC2
protocadherin alpha subfamily C, 2
chr13_-_67804432 4.322 NM_020403
NM_203487
 PCDH9

protocadherin 9

chr3_+_147127151 4.294 NM_003412
 ZIC1
Zic family member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
6.02 1.09e-04 GO:0007156 homophilic cell adhesion
2.68 4.91e-10 GO:0007399 nervous system development
2.57 1.86e-04 GO:0031324 negative regulation of cellular metabolic process
2.50 3.41e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.47 1.92e-02 GO:0031327 negative regulation of cellular biosynthetic process
2.42 2.78e-02 GO:0009890 negative regulation of biosynthetic process
2.41 5.86e-04 GO:0009892 negative regulation of metabolic process
2.40 1.93e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.27 1.35e-02 GO:0022008 neurogenesis
2.26 2.70e-02 GO:0048699 generation of neurons
1.94 3.41e-02 GO:0035556 intracellular signal transduction
1.77 1.66e-04 GO:0048731 system development
1.75 1.33e-02 GO:0048523 negative regulation of cellular process
1.63 3.46e-03 GO:0048856 anatomical structure development
1.62 1.42e-03 GO:0007275 multicellular organismal development
1.56 3.57e-03 GO:0032502 developmental process
1.31 3.43e-02 GO:0050794 regulation of cellular process
1.30 3.44e-02 GO:0050789 regulation of biological process
1.24 2.30e-05 GO:0009987 cellular process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
22.52 5.22e-03 GO:0045295 gamma-catenin binding
15.01 3.16e-02 GO:0030291 protein serine/threonine kinase inhibitor activity
14.08 4.15e-02 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
14.08 4.15e-02 GO:0019198 transmembrane receptor protein phosphatase activity
7.51 3.78e-02 GO:0008013 beta-catenin binding
3.92 3.47e-02 GO:0004721 phosphoprotein phosphatase activity
1.42 6.14e-07 GO:0005515 protein binding
1.16 9.40e-03 GO:0005488 binding