Motif ID: GFI1B.p2

Z-value: 0.826


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GFI1Bchr9_+_135854097-0.171.1e-02Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_119737905 10.553 MCTS1
malignant T cell amplified sequence 1
chrX_+_119738542 10.192 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr5_+_134209426 10.164 NM_024715
TXNDC15
thioredoxin domain containing 15
chr22_+_22735134 8.299 CYAT1
immunoglobulin lambda light chain-like
chr7_-_56101830 7.316 PSPH
phosphoserine phosphatase
chr1_+_211500147 7.245 NM_001033910
TRAF5
TNF receptor-associated factor 5
chr1_+_211500166 6.842 TRAF5
TNF receptor-associated factor 5
chr17_+_70117168 6.811 SOX9
SRY (sex determining region Y)-box 9
chr17_-_56494930 6.624 NM_017763
RNF43
ring finger protein 43
chr10_-_91011516 6.208 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr17_+_70117177 6.157 SOX9
SRY (sex determining region Y)-box 9
chr4_-_186877869 5.842 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr3_+_142375738 5.787 NM_001172312
PLS1
plastin 1
chr1_+_211499956 5.718 NM_004619
TRAF5
TNF receptor-associated factor 5
chr9_+_97521930 5.550 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr22_+_22735207 5.549 IGLJ3
immunoglobulin lambda joining 3
chr4_-_186733372 5.451 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr10_-_91011562 5.398 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr2_+_170662044 5.219 SSB
Sjogren syndrome antigen B (autoantigen La)
chr17_-_56494889 4.763 RNF43
ring finger protein 43

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
2.76 5.09e-03 GO:0044283 small molecule biosynthetic process
2.10 2.00e-02 GO:0032774 RNA biosynthetic process
1.97 2.16e-04 GO:0016070 RNA metabolic process
1.96 1.90e-07 GO:0009058 biosynthetic process
1.93 1.41e-06 GO:0044249 cellular biosynthetic process
1.93 1.94e-04 GO:0010467 gene expression
1.92 9.74e-04 GO:0009059 macromolecule biosynthetic process
1.92 1.44e-03 GO:0034645 cellular macromolecule biosynthetic process
1.91 5.11e-04 GO:0044281 small molecule metabolic process
1.69 1.28e-02 GO:0090304 nucleic acid metabolic process
1.67 1.46e-04 GO:0034641 cellular nitrogen compound metabolic process
1.67 1.40e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.65 1.98e-04 GO:0006807 nitrogen compound metabolic process
1.55 3.08e-03 GO:0071840 cellular component organization or biogenesis
1.53 1.40e-02 GO:0016043 cellular component organization
1.50 1.69e-07 GO:0044237 cellular metabolic process
1.49 1.26e-03 GO:0044260 cellular macromolecule metabolic process
1.43 2.32e-05 GO:0044238 primary metabolic process
1.40 1.14e-02 GO:0043170 macromolecule metabolic process
1.39 1.29e-05 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
2.43 3.54e-02 GO:0044427 chromosomal part
2.01 3.94e-04 GO:0005654 nucleoplasm
1.74 3.53e-03 GO:0031981 nuclear lumen
1.71 1.89e-03 GO:0005829 cytosol
1.69 9.66e-04 GO:0031974 membrane-enclosed lumen
1.69 1.03e-03 GO:0043233 organelle lumen
1.67 3.47e-03 GO:0044428 nuclear part
1.61 1.22e-02 GO:0070013 intracellular organelle lumen
1.51 2.68e-07 GO:0044446 intracellular organelle part
1.50 2.20e-07 GO:0044422 organelle part
1.43 2.62e-02 GO:0032991 macromolecular complex
1.40 7.95e-05 GO:0044444 cytoplasmic part
1.34 1.03e-06 GO:0005737 cytoplasm
1.31 1.78e-13 GO:0044424 intracellular part
1.29 9.99e-13 GO:0005622 intracellular
1.28 5.20e-05 GO:0043231 intracellular membrane-bounded organelle
1.28 5.78e-05 GO:0043227 membrane-bounded organelle
1.27 3.52e-06 GO:0043229 intracellular organelle
1.27 4.31e-06 GO:0043226 organelle
1.09 2.67e-03 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.43 1.10e-04 GO:0003723 RNA binding
1.32 2.54e-04 GO:0005515 protein binding