Motif ID: GGACGGA

Z-value: 0.457


Mature miRNA associated with seed GGACGGA:

NamemiRBase Accession
hsa-miR-184 MIMAT0000454



Activity profile for motif GGACGGA.

activity profile for motif GGACGGA


Sorted Z-values histogram for motif GGACGGA

Sorted Z-values for motif GGACGGA



Network of associatons between targets according to the STRING database.



First level regulatory network of GGACGGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_57045235 5.677 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr20_-_44541002 5.110 NM_001242920
NM_006227
NM_182676
PLTP


phospholipid transfer protein


chr7_+_73442426 4.336 NM_000501
NM_001081752
NM_001081753
NM_001081754
NM_001081755
ELN




elastin




chr20_-_44539597 4.324 NM_001242921
PLTP
phospholipid transfer protein
chr19_+_18794391 3.834 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr1_-_11866079 3.748 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_+_84853585 3.623 NM_031476
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr19_-_4400470 3.322 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr1_-_19229016 3.215 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr1_-_19217384 3.172 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr3_-_58563490 2.762 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chr16_+_66968319 2.632 NM_003869
NM_198061
CES2

carboxylesterase 2

chr11_+_46299161 2.591 NM_052854
CREB3L1
cAMP responsive element binding protein 3-like 1
chr19_-_4400357 2.370 NM_001199944
SH3GL1
SH3-domain GRB2-like 1
chr15_-_79383080 2.335 NM_001145648
NM_002891
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr8_+_102504661 2.261 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr3_+_49506079 2.213 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr3_+_49507470 2.170 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr11_+_117049838 2.043 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr19_-_45909566 1.985 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr17_+_14204326 1.936 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr4_-_174451356 1.877 NM_021973
HAND2
heart and neural crest derivatives expressed 2
chr2_-_157189040 1.839 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_+_2699731 1.804 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr4_+_41362750 1.758 NM_001112717
NM_001112718
NM_014988
LIMCH1


LIM and calponin homology domains 1


chr1_-_44482996 1.726 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr19_-_45908288 1.658 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr1_-_208417635 1.637 NM_025179
PLXNA2
plexin A2
chr8_+_37654395 1.575 NM_032777
GPR124
G protein-coupled receptor 124
chr11_+_66036027 1.565 NM_030981
RAB1B
RAB1B, member RAS oncogene family
chr22_-_41032684 1.431 NM_020831
MKL1
megakaryoblastic leukemia (translocation) 1
chr10_+_131265453 1.389 NM_002412
MGMT
O-6-methylguanine-DNA methyltransferase
chr1_-_21995793 1.388 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr16_-_70323407 1.377 NM_001605
AARS
alanyl-tRNA synthetase
chr11_-_797955 1.366 NM_001191060
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr1_-_44497132 1.306 NM_001024845
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr19_-_42746723 1.291 NM_019884
GSK3A
glycogen synthase kinase 3 alpha
chr5_+_7396030 1.248 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr16_+_1203240 1.248 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr7_+_90893735 1.233 NM_003505
FZD1
frizzled family receptor 1
chr16_-_75590107 1.221 NM_001077416
NM_001077418
NM_001077419
TMEM231


transmembrane protein 231


chr15_+_31619043 1.196 NM_015995
KLF13
Kruppel-like factor 13
chr22_-_39636906 1.118 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide
chr1_-_21978287 1.114 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr5_-_73937248 1.106 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr7_-_44365019 1.083 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr12_-_63328663 1.013 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr10_-_101190201 0.997 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr11_-_798196 0.964 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr2_+_120770602 0.936 NM_001184937
NM_001184939
NM_020909
EPB41L5


erythrocyte membrane protein band 4.1 like 5


chr5_-_171433876 0.900 NM_012300
NM_033644
NM_033645
FBXW11


F-box and WD repeat domain containing 11


chr22_+_22020272 0.883 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr3_+_189349215 0.881 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr5_+_65017993 0.864 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr11_-_64546201 0.838 NM_004630
NM_201995
NM_201997
NM_201998
SF1



splicing factor 1



chr20_+_57414794 0.742 NM_016592
GNAS
GNAS complex locus
chr5_-_172756505 0.736 NM_003714
STC2
stanniocalcin 2
chr9_-_101470836 0.727 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr22_+_21771661 0.694 NM_015094
HIC2
hypermethylated in cancer 2
chr12_+_121124922 0.656 NM_014730
MLEC
malectin
chr18_+_47088400 0.637 NM_006033
LIPG
lipase, endothelial
chr9_+_34958171 0.624 NM_015297
KIAA1045
KIAA1045
chr4_+_41614911 0.621 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr16_+_1664640 0.583 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr6_+_108882068 0.562 NM_001455
FOXO3
forkhead box O3
chr6_+_27782793 0.560 NM_003521
HIST1H2BM
histone cluster 1, H2bm
chr19_+_56124958 0.560 NM_001195605
ZNF865
zinc finger protein 865
chr9_+_140033588 0.550 NM_000832
NM_001185090
NM_001185091
NM_007327
NM_021569
GRIN1




glutamate receptor, ionotropic, N-methyl D-aspartate 1




chr5_-_139422805 0.539 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chr21_-_36260972 0.528 NM_001001890
NM_001122607
RUNX1

runt-related transcription factor 1

chr1_+_110453232 0.512 NM_000757
NM_172210
NM_172212
CSF1


colony stimulating factor 1 (macrophage)


chr15_-_79298001 0.497 NM_153815
RASGRF1
Ras protein-specific guanine nucleotide-releasing factor 1
chr6_+_160769365 0.470 NM_021977
SLC22A3
solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr5_+_176560627 0.399 NM_022455
NSD1
nuclear receptor binding SET domain protein 1
chr1_-_179112178 0.374 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr8_-_145550536 0.342 NM_012079
DGAT1
diacylglycerol O-acyltransferase 1
chr19_+_10764896 0.336 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr2_+_206547131 0.327 NM_003872
NM_018534
NM_201264
NM_201266
NM_201267
NM_201279
NRP2





neuropilin 2





chr22_-_32146119 0.322 NM_173566
PRR14L
proline rich 14-like
chr12_-_125052009 0.319 NM_001077261
NM_001206654
NM_006312
NCOR2


nuclear receptor corepressor 2


chr11_+_118978087 0.308 NM_014807
C2CD2L
C2CD2-like
chr21_-_36421586 0.269 NM_001754
RUNX1
runt-related transcription factor 1
chr6_+_108881010 0.267 NM_201559
FOXO3
forkhead box O3
chr20_-_3687774 0.248 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr20_+_51801821 0.235 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr1_-_179198814 0.221 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr1_+_22778343 0.187 NM_001083621
NM_014870
ZBTB40

zinc finger and BTB domain containing 40

chr7_-_72722786 0.154 NM_001168347
NM_001168348
NM_018044
NM_148956
NSUN5



NOP2/Sun domain family, member 5



chr16_-_3068161 0.153 NM_021195
CLDN6
claudin 6
chr19_+_11071792 0.101 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr3_+_189507448 0.085 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr22_-_39640956 0.072 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide
chr4_-_96470350 0.070 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chr20_+_51588945 0.056 NM_173485
TSHZ2
teashirt zinc finger homeobox 2
chr12_+_109915430 0.015 NM_130466
NM_183415
UBE3B

ubiquitin protein ligase E3B

chr4_-_1242882 0.004 NM_001012614
NM_001328
CTBP1

C-terminal binding protein 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.56 9.93e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.43 1.42e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
3.65 1.45e-03 GO:0010604 positive regulation of macromolecule metabolic process
4.76 1.55e-03 GO:0010628 positive regulation of gene expression
3.54 2.13e-03 GO:0031325 positive regulation of cellular metabolic process
4.76 3.91e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.42 4.38e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.31 4.51e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.35 4.58e-03 GO:0009893 positive regulation of metabolic process
2.35 7.59e-03 GO:0051171 regulation of nitrogen compound metabolic process
4.43 7.94e-03 GO:0051254 positive regulation of RNA metabolic process
3.83 1.57e-02 GO:0031328 positive regulation of cellular biosynthetic process
3.77 1.88e-02 GO:0009891 positive regulation of biosynthetic process
5.71 4.32e-02 GO:0043434 response to peptide hormone stimulus
2.43 4.37e-02 GO:0048523 negative regulation of cellular process
4.04 4.39e-02 GO:0009719 response to endogenous stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
6.51 1.19e-03 GO:0016563 transcription activator activity