Motif ID: GGCAGUG

Z-value: 2.332


Mature miRNA associated with seed GGCAGUG:

NamemiRBase Accession
hsa-miR-34a MIMAT0000255
hsa-miR-34c-5p MIMAT0000686
hsa-miR-449a MIMAT0001541
hsa-miR-449b MIMAT0003327



Activity profile for motif GGCAGUG.

activity profile for motif GGCAGUG


Sorted Z-values histogram for motif GGCAGUG

Sorted Z-values for motif GGCAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GGCAGUG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_79257772 68.498 NM_001135805
 SYT1
synaptotagmin I
chr12_+_79439432 62.348 NM_001135806
 SYT1
synaptotagmin I
chr12_+_79258448 59.261 NM_005639
 SYT1
synaptotagmin I
chr18_-_74729049 56.855 NM_001025081
NM_001025090
NM_001025092
NM_002385
 MBP



myelin basic protein



chr10_+_105036783 51.361 NM_032727
 INA
internexin neuronal intermediate filament protein, alpha
chr17_-_8066254 46.928 NM_014232
 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr20_+_10199455 39.828 NM_003081
NM_130811
 SNAP25

synaptosomal-associated protein, 25kDa

chr3_-_58563490 38.723 NM_001076778
NM_007177
 FAM107A

family with sequence similarity 107, member A

chr6_-_6007632 38.298 NM_016588
 NRN1
neuritin 1
chr2_+_203499819 34.908 NM_173511
 FAM117B
family with sequence similarity 117, member B
chr5_-_11903964 34.307 NM_001332
 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr10_-_62149487 33.394 NM_020987
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr10_+_126150340 32.742 NM_001167880
NM_022126
 LHPP

phospholysine phosphohistidine inorganic pyrophosphate phosphatase

chr17_+_40834571 32.021 NM_003632
 CNTNAP1
contactin associated protein 1
chr14_+_23299083 31.598 NM_178336
NM_180982
NM_181304
NM_181305
NM_181306
NM_181307
 MRPL52





mitochondrial ribosomal protein L52





chr20_+_37434294 30.597 NM_001172735
NM_015568
 PPP1R16B

protein phosphatase 1, regulatory subunit 16B

chr10_-_62493282 30.519 NM_001204403
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr7_-_73133917 30.477 NM_001165903
NM_004603
 STX1A

syntaxin 1A (brain)

chr17_-_37764165 30.105 NM_006160
 NEUROD2
neurogenic differentiation 2
chr17_+_43971655 29.876 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
 MAPT







microtubule-associated protein tau








Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
enrichment   p-value GO term description
17.01 2.88e-02 GO:0032329 serine transport
7.56 8.83e-03 GO:0016079 synaptic vesicle exocytosis
5.85 2.82e-03 GO:0048489 synaptic vesicle transport
4.86 3.24e-05 GO:0007269 neurotransmitter secretion
4.02 3.35e-02 GO:0007612 learning
3.90 2.32e-07 GO:0007156 homophilic cell adhesion
3.87 3.50e-04 GO:0001505 regulation of neurotransmitter levels
3.69 1.04e-04 GO:0003001 generation of a signal involved in cell-cell signaling
3.69 1.04e-04 GO:0023061 signal release
3.50 1.02e-03 GO:0006836 neurotransmitter transport
3.02 3.50e-02 GO:0007611 learning or memory
2.91 3.78e-02 GO:0050890 cognition
2.68 5.32e-06 GO:0016337 cell-cell adhesion
2.52 2.84e-07 GO:0007409 axonogenesis
2.47 4.06e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.44 1.02e-04 GO:0007411 axon guidance
2.43 1.15e-06 GO:0007268 synaptic transmission
2.40 1.55e-07 GO:0000904 cell morphogenesis involved in differentiation
2.39 8.30e-09 GO:0048666 neuron development
2.39 2.68e-07 GO:0019226 transmission of nerve impulse

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
3.95 3.82e-06 GO:0019717 synaptosome
2.67 6.71e-10 GO:0045202 synapse
2.42 5.12e-05 GO:0044456 synapse part
2.21 3.42e-02 GO:0034702 ion channel complex
2.13 2.28e-04 GO:0043005 neuron projection
1.98 3.23e-05 GO:0030054 cell junction
1.64 3.61e-10 GO:0044459 plasma membrane part
1.58 1.89e-02 GO:0042995 cell projection
1.56 9.61e-04 GO:0031226 intrinsic to plasma membrane
1.51 5.66e-03 GO:0005887 integral to plasma membrane
1.44 6.28e-11 GO:0005886 plasma membrane
1.43 9.27e-11 GO:0071944 cell periphery
1.19 1.02e-04 GO:0016020 membrane
1.17 1.46e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.88 1.07e-02 GO:0030695 GTPase regulator activity
1.87 1.05e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.84 5.23e-04 GO:0005509 calcium ion binding
1.70 3.62e-02 GO:0004672 protein kinase activity
1.65 2.46e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.26 1.04e-02 GO:0046872 metal ion binding
1.24 2.41e-02 GO:0043169 cation binding
1.24 2.89e-02 GO:0043167 ion binding
1.19 2.33e-04 GO:0005515 protein binding
1.11 2.00e-04 GO:0005488 binding